Submassive Pulmonary Embolism.

Pulmonary embolism (PE) presents a spectrum of hemodynamic consequences, ranging from being asymptomatic to a life-threatening medical emergency. Management of submassive and massive PE often involves clinicians from multiple specialties, which can potentially delay the development of a unified treatment plan. In addition, patients with submassive PE can deteriorate after their presentation and require escalation of care. Underlying comorbidities such as chronic obstructive pulmonary disease, cancer, congestive heart failure, and interstitial lung disease can impact the patient's hemodynamic ability to tolerate submassive PE. In this review, we address the definitions, risk stratification (clinical, laboratory, and imaging), management approaches, and long-term outcomes of submassive PE. We also discuss the role of the PE response team in management of patients with PE.

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This review covers definitions, risk stratification with clinical, laboratory and imaging tools, management and long-term outcomes of submassive pulmonary embolism, noting that comorbidities such as COPD, cancer and heart failure affect hemodynamic tolerance and that multispecialty care can potentially delay unified treatment planning.

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