The Complete Mitochondrial Genome of(Annelida: Hirudinea: Glossiphoniidae).
Research article published in Genes (2023)
Abstract
Torix tukubana is a poorly understood proboscidate leech species, generally an ectoparasite on amphibian species. In this study, the complete mitochondrial genome (mitogenome) of T. tukubana was sequenced using next-generation sequencing (NGS), and the essential characteristics, gene arrangement, and phylogenetic relationship were analyzed. The results showed that the T. tukubana mitogenome was 14,814 bp in length, consisting of 13 protein-coding genes (PCGs), 22 tRNAs, 2 rRNAs, and 1 control region (CR). The mitogenome composition presented a strong A + T bias (73.6%). All tRNAs had the typical clover structure except the trnS1 (TCT), whose dihydrouridine (DHU) arm was short, having only one complementary base pair. Additionally, 8 gene order patterns were identified among 25 known Hirudinea species, and T. tukubana was identical to the Hirudinea ground pattern. A phylogenetic analysis based on 13 PCGs indicated that all the studied species clustered into three main clades. The relationships among Hirudinea species were basically consistent with their gene arrangement results, but different from their morphological taxonomy. T. tukubana was in the monophyletic group of Glossiphoniidae, a finding consistent with previous research. Our results provided the essential characteristics of the T. tukubana mitogenome. As the first complete mitogenome of Torix, it could offer valuable information for a systematic understanding of the Hirudinea species.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Resumen
is a poorly understood proboscidate leech species, generally an ectoparasite on amphibian species. In this study, the complete mitochondrial genome (mitogenome) ofwas sequenced using next-generation sequencing (NGS), and the essential characteristics, gene arrangement, and phylogenetic relationship were analyzed.
Por qué esto importa para la hirudoterapia
Este estudio secuenció y caracterizó el genoma mitocondrial completo (14,814 pb; 13 genes codificantes de proteínas, 22 tRNAs, 2 rRNAs, una región de control, con un fuerte sesgo A+T) de Torix tukubana, una sanguijuela con probóscide descrita como ectoparásito de anfibios, y utilizó 13 genes codificantes de proteínas para ubicarla dentro de la familia Glossiphoniidae. Para la hirudoterapia, esto representa un contexto filogenético y taxonómico de base sobre la biodiversidad de las sanguijuelas en lugar de evidencia clínicamente aplicable: Torix no es la sanguijuela medicinal Hirudo medicinalis utilizada en terapia, y el resumen no reporta compuestos salivales, actividad anticoagulante ni aplicación médica. El trabajo es un artículo descriptivo de genómica comparativa y filogenética, por lo que su valor para ASH se limita a la sistemática de las sanguijuelas, y no debe extraerse ninguna inferencia clínica sobre la hirudoterapia a partir del mismo.
Citación
The Complete Mitochondrial Genome of(Annelida: Hirudinea: Glossiphoniidae).
Zhu X et al. · Genes, 2023
Contexto clínico relacionado
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Añadido a la biblioteca ASH: May 28, 2026 · Última actualización del sitio: June 18, 2026