Is colour Doppler ultrasound a sensitive screening method in diagnosing deep vein thrombosis after hip surgery?

Comparative study published in Thromb Haemost (1996)

Zuletzt aktualisiert: 18. Juni 2026Geprüft von: ASH Editorial Board

Forschungsartikel – EvidenzreviewArtikelreferenz

Evidence: Observational studySpeichel-PharmakologieArzneimittelentwicklungMagnusson M et al. · Thromb Haemost, 1996

Abstract

Patients under going orthopedic surgery are at high risk of developing deep vein thrombosis. One hundred and thirty-eight consecutive patients undergoing total hip replacement or hip fracture surgery were included in this study. They were surveilled with colour Doppler ultrasound (CDU) and bilateral ascending contrast phlebography. The prevalence of proximal and distal DVT in this study was 5.8% and 20.3% respectively. CDU has a satisfactory sensitivity in patients with symptomatic deep vein thrombosis, especially in the proximal region. These results could not be confirmed in the present study of asymptomatic patients. The sensitivity was 62.5% (95% confidence interval: C.I. 24-91%) and the specificity 99.6% (C.I. 98-100%) for proximal DVT; 53.6% (C.I. 34-73%) and 98% (C.I. 96-99%) respectively for distal thrombi. the overall sensitivity was 58.1% (C.I. 39-75%) and the specificity 98% (C.I. 96-99%). The positive predictive value was 83.3% (C.I. 36-99%) and 75% (C.I. 51-91%) for proximal and distal DVT respectively. The negative predictive value was 98.9% (C.I. 98-100%) and 94.9% (C.I. 92-98%) for proximal and distal DVT respectively. The results of this study showed that even with a highly specialised and experienced investigator the sensitivity of CDU was too low to make it suitable for screening purposes in a high risk surgical population.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeComparative StudyJournal Article

Indexed MeSH termsAnticoagulantsDalteparinDextransHip FracturesHip ProsthesisHirudin TherapyHirudinsHumansIncidencePhlebographyPostoperative CarePostoperative Complications

Zusammenfassung

138 patients with total hip replacement; CDU sensitivity 58.1% vs phlebography; insufficient sensitivity for routine asymptomatic screening despite use of hirudin DVT prophylaxis.

Warum dies für die Hirudotherapie relevant ist

Diese Studie evaluierte den Farbdoppler-Ultraschall (FDU) als Screening-Verfahren für tiefe Venenthrombosen bei 138 konsekutiven Patienten, die sich einer Totalendoprothese des Hüftgelenks oder einer Hüftfraktur-Operation unterzogen, und verglich ihn mit der beidseitigen aszendierenden Kontrastphlebographie. Sie berichtete eine Gesamtsensitivität von 58,1 % und eine Spezifität von 98 % und kam zu dem Schluss, dass die FDU-Sensitivität für das Screening in dieser Hochrisiko-chirurgischen Population zu niedrig war. Ihre Relevanz für ASH ist nur indirekt: Die Studie betrifft diagnostische Bildgebung nach Hüftoperationen und untersucht weder Hirudotherapie, Blutegel-Sekretom noch irgendeine antikoagulatorische Intervention. Im Abstract werden keine blutegelbezogenen Befunde, Schlussfolgerungen oder Wirkstoffe diskutiert.