Evolving Antibiotic Resistance of Aeromonas Species in Finger Replantation
Case series published in Surgical Infections (2019)
Abstract
Background: Infections with Aeromonas spp. are a recognized complication of leech therapy for circulatory complications in replanted digits. Ciprofloxacin is commonly used empirically for Aeromonas coverage in such cases. Evolving resistance patterns of Aeromonas should be considered in designing an antibiotic strategy. Methods: Three consecutive patients with complicated replantations had site cultures yielding Aeromonas isolates resistant to ciprofloxacin. These cultures were analyzed to identify effective antibiotic agents. Results: Each Aeromonas isolate, and each additional site organism, was sensitive to cefepime. Conclusion: Our routine antibiotic coverage for leech application has been changed to cefepime. Aeromonas sensitivities and resistances should be monitored to adapt to future changes in appropriate antibiotics.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Zusammenfassung
Three consecutive replantations with leech application yielded ciprofloxacin-resistant Aeromonas isolates sensitive to cefepime, motivating change of routine antibiotic coverage for leech therapy to cefepime.
Warum dies für die Hirudotherapie relevant ist
This article reports on three consecutive patients with complicated finger replantations whose site cultures yielded Aeromonas isolates resistant to ciprofloxacin, the antibiotic commonly used empirically for Aeromonas coverage during leech therapy for circulatory complications in replanted digits. All Aeromonas isolates and additional site organisms were sensitive to cefepime, prompting the authors to change their routine antibiotic coverage for leech application to cefepime. This is relevant to hirudotherapy practice because Aeromonas infection is a recognized complication of leech therapy, and evolving resistance patterns directly affect antibiotic strategy. The authors recommend ongoing monitoring of Aeromonas sensitivities and resistances. However, the findings are based on only three patients and may not establish the prevalence of resistance patterns in the broader population.
Zitation
Evolving Antibiotic Resistance of Aeromonas Species in Finger Replantation.
Mokhtar K, Culnan DM, Lineaweaver WC · Surgical infections, 2019
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