Американское общество гирудотерапии

The place of chemical leeching with heparin in digital replantation

Technique paper published in Plastic and Reconstructive Surgery (2007)

Последнее обновление: June 18, 2026Рецензент: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Research reportРазработка лекарственных препаратовКлинические исследованияYokoyama T et al. · Plastic and reconstructive surgery, 2007

Abstract

BACKGROUND: In patients with replanted digits, systemic heparinization or other techniques may be used for prevention of thrombosis of the vascular anastomoses or to prevent coagulation at the drainage site (e.g., a fish-mouth incision or partially removed nail). However, systemic heparin may be contraindicated or require cautious administration in certain patients. The authors injected calcium heparin subcutaneously into the congested replanted digits of seven patients with a history of or undergoing treatment for hemorrhoids or gastric ulcer and drained the congestion by means of a fish-mouth incision. METHODS: With this method, 0.8 ml (20,000 U) of calcium heparin for subcutaneous injection was diluted with 1.2 ml of saline to prepare a solution containing 1000 U in 0.1 ml; this calcium heparin solution (1000 U) was initially injected into the tip of the congested digit. If required, additional doses of 500 U each were administered every 24 hours until the congestion improved. RESULTS: No worsening of bleeding from hemorrhoids or gastric ulcer was seen after the administration of calcium heparin in these patients. Regarding duration of action, continuous bleeding for approximately 6 hours was obtained after subcutaneous injection of 1000 U, and thereafter, adequate drainage was achieved for approximately 24 hours by stimulating the drainage site. CONCLUSIONS: Among patients in whom systemic heparin is contraindicated or who require cautious administration, this is a very effective technique in those in whom congestion fails to improve despite thrombectomy, patients in whom thrombectomy or vascular reanastomosis is not possible, and patients with congestion caused by narrow anastomosed veins.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article
Indexed MeSH termsAdultAmputation, TraumaticCohort StudiesContraindicationsDose-Response Relationship, DrugDrug Administration ScheduleFinger InjuriesHeparinHumansInfusions, IntravenousInjections, SubcutaneousMale

Резюме

Describes subcutaneous calcium heparin injection at congested replanted digit tip as 'chemical leech' alternative for patients in whom systemic heparin is contraindicated.

Почему это важно для гирудотерапии

This study described a technique in which calcium heparin was injected subcutaneously into congested replanted digits of seven patients in whom systemic heparin was contraindicated or required cautious administration, with congestion drained via a fish-mouth incision. Adequate drainage was achieved without worsening bleeding from conditions such as hemorrhoids or gastric ulcers. The abstract makes no mention of leeches, hirudotherapy, or any leech-derived substance. Therefore, the relevance to ASH is negligible; the study concerns a surgical bleeding-management technique involving heparin and does not involve or compare against leech therapy.

Цитирование

The place of chemical leeching with heparin in digital replantation.

Yokoyama T et al. · Plastic and reconstructive surgery, 2007

Связанный клинический контекст

Добавлено в библиотеку ASH: May 27, 2026 · Последнее обновление сайта: June 18, 2026

Этот сайт предоставляет образовательную информацию и не является медицинской консультацией, диагнозом или рекомендацией по лечению. Гирудотерапия сопряжена с клинически значимыми рисками и должна проводиться только квалифицированными клиницистами в рамках институционально утверждённых протоколов. Разрешение FDA 510(k) для медицинских пиявок ограничено определёнными показаниями; обсуждения исследовательского и нелицензионного применения отмечены соответствующим образом. Для индивидуальных медицинских рекомендаций обратитесь к квалифицированному медицинскому специалисту.