Prevention and Treatment of Lower Limb Deep Vein Thrombosis after Radiofrequency Catheter Ablation: Results of a Prospective active controlled Study
Clinical trial published in Scientific reports (2016)
Abstract
We conducted a prospective, single-center, active controlled study from July 2013 to January 2015, in Chinese patients with rapid ventricular arrhythmia who had received radiofrequency catheter ablation (RFCA) treatment to determine formation of lower extremity deep vein thrombosis (LDVT) post RFCA procedure, and evaluated the effect of rivaroxaban on LDVT. Patients with asymptomatic pulmonary thromboembolism who had not received any other anticoagulant and had received no more than 36 hours of treatment with unfractionated heparin were included. Post RFCA procedure, patients received either rivaroxaban (10 mg/d for 14 days beginning 2-3 hours post-operation; n = 86) or aspirin (100 mg/d for 3 months beginning 2-3 hours post-operation; n = 90). The primary outcome was a composite of LDVT occurrence, change in diameter of femoral veins, and safety outcomes that were analyzed based on major or minor bleeding events. In addition, blood flow velocity was determined. No complete occlusive thrombus or bleeding events were reported with either of the group. The lower incidence rate of non-occluded thrombus in rivaroxaban (5.8%) compared to the aspirin group (16.7%) indicates rivaroxaban may be administered post-RFCA to prevent and treat femoral venous thrombosis in a secure and effective way with a faster inset of action than standard aspirin therapy.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Резюме
We conducted a prospective, single-center, active controlled study from July 2013 to January 2015, in Chinese patients with rapid ventricular arrhythmia who had received radiofrequency catheter ablation (RFCA) treatment to determine formation of lower extremity deep vein thrombosis (LDVT) post RFCA procedure, and evaluated the effect of rivaroxaban on LDVT.
Почему это важно для гирудотерапии
This prospective, active controlled study evaluated the effectiveness and safety of rivaroxaban versus aspirin in preventing lower extremity deep vein thrombosis (LDVT) in 176 Chinese patients following radiofrequency catheter ablation. The study found that rivaroxaban resulted in a lower incidence of non-occluded thrombus compared to aspirin, without any complete occlusive thrombi or bleeding events. There is no direct relevance to the American Society of Hirudotherapy, leech therapy, or the leech secretome, as the abstract does not mention leeches, hirudin, or any leech-derived compounds. The research is solely focused on comparing standard pharmaceutical anticoagulants and antiplatelets to manage post-procedural venous thrombosis, offering no applicable data for hirudotherapy research.
Цитирование
Prevention and Treatment of Lower Limb Deep Vein Thrombosis after Radiofrequency Catheter Ablation: Results of a Prospective active controlled Study
Li L et al. · Scientific reports, 2016
Связанный клинический контекст
Узнайте, как это исследование связано с клинической практикой
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