Bivalirudin as a Systemic Anticoagulant and Flush Solution Additive for Sequential Mitral and Tricuspid Valve Percutaneous Edge-to-Edge Repair in a Patient With Heparin-Induced Thrombocytopenia
Research article published in Journal of cardiothoracic and vascular anesthesia (2021)
Abstract
Herein the case of a patient with a prior history of heparin-induced thrombocytopenia who underwent percutaneous mitral valve edge-to-edge repair that was followed by a tricuspid edge-to-edge repair two months later is presented. Recommendations exist for systemic anticoagulant alternatives for percutaneous mitral valve edge-to-edge repair with the MitraClip device (Abbott, Chicago, IL), but minimal guidance and experience are present regarding alternative systemic anticoagulation during the performance of right-sided interventions, including tricuspid edge-to-edge repair (TriClip; Abbott). Notably, there is no clear consensus regarding the use of an alternative anticoagulant in the catheter flush solution for the delivery systems used during these procedures, particularly for right-sided interventions.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Resumen
Bivalirudin as a Systemic Anticoagulant and Flush Solution Additive for Sequential Mitral and Tricuspid Valve Percutaneous Edge-to-Edge Repair in a Patient With Heparin-Induced Thrombocytopenia.
Por qué esto importa para la hirudoterapia
Este reporte de caso describe un paciente con antecedentes de trombocitopenia inducida por heparina que fue sometido a una reparación percutánea borde a borde de la válvula mitral seguida de una reparación borde a borde de la válvula tricúspide dos meses después. Los autores destacan la falta de directrices establecidas y de experiencia clínica respecto a la anticoagulación sistémica alternativa, así como la falta de consenso sobre anticoagulantes alternativos en las soluciones de irrigación de catéteres, particularmente para intervenciones del lado derecho. El resumen no especifica qué anticoagulantes alternativos se utilizaron ni menciona ninguna conexión con sanguijuelas, hirudina ni terapia con sanguijuelas. Por lo tanto, este artículo no tiene una relevancia defendible para el ámbito de la ASH.
Citación
Bivalirudin as a Systemic Anticoagulant and Flush Solution Additive for Sequential Mitral and Tricuspid Valve Percutaneous Edge-to-Edge Repair in a Patient With Heparin-Induced Thrombocytopenia
Colbaugh Z et al. · Journal of cardiothoracic and vascular anesthesia, 2021
Contexto clínico relacionado
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Añadido a la biblioteca ASH: May 27, 2026 · Última actualización del sitio: 18 de junio de 2026