Американское общество гирудотерапии

Prophylactic versus reactive leech therapy for venous congestion after fingertip replantation: A retrospective comparative study and literature review

Comparative cohort study published in JPRAS Open (2025)

Последнее обновление: June 18, 2026Рецензент: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Research reportКлинические исследованияKameda Y, Motomiya M, Watanabe N, Ota M, Iwasaki N · JPRAS open, 2025

Abstract

INTRODUCTION: Although the efficacy of medicinal leech therapy for managing venous congestion after fingertip replantation is well recognized, an optimal, standardized application protocol remains undefined. This study evaluated clinical outcomes under two application strategies and conducted a literature review to explore optimal protocols. MATERIALS AND METHODS: We retrospectively analyzed 25 digits that received leech therapy after fingertip replantation or revascularization at our institution (April 2015-March 2023). Group A (n = 12) underwent reactive leeching in response to clinical congestion, whereas Group B (n = 13) received prophylactic leeching two to three times daily from the early postoperative period, prior to any clinical signs of congestion. A literature search was conducted in accordance with PRISMA 2020 guidelines. RESULTS: Complete survival was achieved in 8/12 digits (67 %) in Group A and 12/13 (92 %) in Group B. Early postoperative complications occurred in 6/12 versus 1/13 digits, and re-operations in 6/12 versus 1/13 digits, both significantly more frequent in Group A (p = 0.030). Only one Group A patient required transfusion owing to preexisting anemia. One case of Aeromonas hydrophila infection was identified. Functional and aesthetic outcomes were satisfactory in both groups. Combining our data with 129 digits from the literature yielded an overall survival rate of 81 % (124/154), although few reports detailed specific leech protocols. CONCLUSIONS: Effective bleeding control and timely congestion prevention are essential in artery-only fingertip replantation. A prophylactic, regularly scheduled leeching protocol appears to improve outcomes and may be adopted as a standard approach given its favorable risk-benefit profile.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article

Резюме

Retrospective comparison of 25 fingertip replantation digits: prophylactic scheduled leeching achieved 92% complete survival versus 67% for reactive leeching, with significantly fewer early postoperative complications and re-operations.

Почему это важно для гирудотерапии

This retrospective study analyzed 25 digits that received leech therapy after fingertip replantation or revascularization, comparing reactive leeching in response to clinical congestion (Group A, n=12) versus prophylactic leeching two to three times daily from the early postoperative period before any clinical signs of congestion (Group B, n=13). Complete survival was 67% in Group A versus 92% in Group B, with significantly fewer early postoperative complications and re-operations in the prophylactic group. One Group A patient required transfusion due to preexisting anemia, and one Aeromonas hydrophila infection was identified. Combining their data with literature cases yielded an overall survival rate of 81% across 154 digits, though the authors note that few reports detailed specific leech protocols. The authors suggest a prophylactic leeching protocol may improve outcomes, which is relevant to hirudotherapy protocol standardization, though this is a retrospective analysis.

Цитирование

Prophylactic versus reactive leech therapy for venous congestion after fingertip replantation: A retrospective comparative study and literature review.

Kameda Y, Motomiya M, Watanabe N, Ota M, Iwasaki N · JPRAS open, 2025

Связанный клинический контекст

Узнайте, как это исследование связано с клинической практикой

Добавлено в библиотеку ASH: May 26, 2026 · Последнее обновление сайта: June 18, 2026

Этот сайт предоставляет образовательную информацию и не является медицинской консультацией, диагнозом или рекомендацией по лечению. Гирудотерапия сопряжена с клинически значимыми рисками и должна проводиться только квалифицированными клиницистами в рамках институционально утверждённых протоколов. Разрешение FDA 510(k) для медицинских пиявок ограничено определёнными показаниями; обсуждения исследовательского и нелицензионного применения отмечены соответствующим образом. Для индивидуальных медицинских рекомендаций обратитесь к квалифицированному медицинскому специалисту.