Standardized protocol for artery-only fingertip replantation
Prospective cohort published in J Hand Surg Am (2010)
Abstract
PURPOSE: Artery-only fingertip replantation can be reliable if low-resistance flow through the replant is maintained until venous outflow is restored naturally. Injuring the tip of the replant to promote ongoing bleeding augmented with anticoagulation usually accomplishes this; however, such management results in prolonged hospitalization. In this study, we analyzed the outcomes of artery-only fingertip replantation using a standardized postoperative protocol consisting of dextran-40, heparin, and leech therapy. METHODS: Between 2001 and 2008, we performed 19 artery-only fingertip replants for 17 patients. All patients had the replanted nail plate removed and received intravenous dextran-40, heparin, and aspirin to promote fingertip bleeding and vascular outflow. Anticoagulation was titrated to promote a controlled bleed until physiologic venous outflow was restored by neovascularization. We used medicinal leeches and mechanical heparin scrubbing for acute decongestion. By postoperative day 6, bleeding was no longer promoted. We initiated fluorescent dye perfusion studies to assess circulatory competence and direct further anticoagulant intervention if necessary. The absence of bleeding associated with an initial rise followed by an appropriate fall in fluorescent dye concentration would trigger a weaning of anticoagulation. RESULTS: All of the 19 replants survived. The average length of hospital stay was 9 days (range, 7-17 d). Eleven patients received blood transfusions. The average transfusion was 1.8 units (range, 0-9 units). All patients were happy with the decision to replant, and the cosmetic result. CONCLUSIONS: A protocol that promotes temporary, controlled bleeding from the fingertip is protective of artery-only replants distal to the distal interphalangeal joint until physiologic venous outflow is restored. The protocol described is both safe and reliable. The patient should be informed that such replant attempts may result in the need for transfusions and extended hospital stays, factors that can help the physician and patient decide whether to proceed with replantation. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Zusammenfassung
Nineteen artery-only fingertip replants managed with dextran-40, heparin, aspirin, and medicinal leech therapy plus mechanical heparin scrubbing. 100% replant survival; mean hospital stay 9 days; 11/17 patients required transfusion.
Warum dies für die Hirudotherapie relevant ist
This study reports outcomes of a standardized postoperative protocol for 19 artery-only fingertip replants in 17 patients, using dextran-40, heparin, aspirin, and medicinal leech therapy for acute decongestion. All 19 replants survived, with an average hospital stay of 9 days (range 7-17 days). Eleven patients required blood transfusions (average 1.8 units, range 0-9 units). For ASH's domain, this study describes leech therapy as one component of a multi-modal protocol promoting temporary controlled bleeding from the fingertip until physiologic venous outflow is restored by neovascularization. The honest caveat is that this involves a small number of patients, and leech therapy was one element of a multi-modal protocol, so its independent contribution to outcomes cannot be isolated. The substantial transfusion requirements highlight morbidity associated with this approach, which includes but is not limited to leeching.
Zitation
Standardized protocol for artery-only fingertip replantation.
Buntic RF, Brooks D · The Journal of hand surgery, 2010
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