Amerikanische Gesellschaft für Hirudotherapie

Publication Tracker \u2014 ASH

Live timeline of 10030 PMID-verified articles ASH tracks. Filter by category to explore the literature growth toward our 10,000-paper coverage goal.

Zuletzt aktualisiert: May 27, 2026Geprüft von: Andrei Dokukin, MD
Literature surveillanceEditorial reference \u2014 not clinical advice

This page is the public face of ASH's literature-tracking pipeline. Every entry here is parsed from PubMed metadata directly, cross-checked against the article's real PMID, and committed into the open-source registry behind this site. Hand-curated registries are tracked separately at PMID Audit Status.

The corpus grows continuously as new PubMed-indexed hirudotherapy and leech-derived-compound papers are published. The 10,000-article goal is the coverage threshold needed to consider ASH's literature surveillance comprehensive across all leech-related biomedical sub-fields.

10030

Total tracked articles

PMID-verified, auto-imported from PubMed

2007

Added in last 12 months

Rolling window ending 2026-05-27

100%

Progress toward 10,000-paper goal

Filter by category

Showing 802 articles in Genomics & Proteomics. Clear filter

Timeline by publication year

2026

37 articlesCurrent year
Clinical Trials2026PMID 41977299

A Pilot Study on Multigenic Thrombophilic Risk in Recurrent Pregnancy Loss: Interactions Between MTHFR Polymorphisms and Classical Thrombophilia-Associated SNPs

Badulescu OV et al. · International journal of molecular sciences

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2026PMID 41903649

Bloody diarrhea associated with cytotoxic Aeromonas enteropelogenes harboring act and aerA genes: A case report highlighting diagnostic pitfalls.

Ohno T et al. · Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

Added to ASH registry: 2026-05-28

Genomics & Proteomics2026PMID 41781760

Brain natriuretic peptide protects against acute pulmonary embolism-induced pulmonary vasoconstriction through natriuretic peptide receptor C

Gao et al. · Basic research in cardiology

Added to ASH registry: 2026-05-28

Clinical Trials2026PMID 42151824

Cerebral venous sinus thrombosis secondary to nasopharyngeal abscess with Klebsiella pneumoniae infection in an elderly patient with multiple comorbidities: a case report and literature review

Wu Y et al. · BMC infectious diseases

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2026PMID 42112451

Culture, qPCR, and genome-based surveillance of,, andin school wastewater from Santiago, Chile.

Cortez-Astorga A et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2026PMID 41625157

Distribution characteristics of integrons and correlation analysis of antibiotic resistance in.

Yang T et al. · Frontiers in cellular and infection microbiology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2026PMID 41819513

Diversity and expression pattern of novel macin genes in the earthworm, Eiseniaandrei.

Park BJ et al. · Developmental and comparative immunology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2026PMID 41981488

Gastrointestinal infection caused by five different strains of Aeromonas caviae and one of Aeromonas veronii: case report and review of the literature.

Recio Comí G et al. · BMC infectious diseases

Added to ASH registry: 2026-05-28

Clinical Trials2026PMID 42168863

Ionized hypocalcemia prior to continuous veno-venous hemodialysis initiation: prevalence and consequences

Thibault B et al. · BMC anesthesiology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2026PMID 41524924

Isolation of Proteus sp. Closely Related to P. Vulgaris (Vulgaris/hauseri Complex) from Ornamental Koi (Cyprinus rubrofuscus) and its Pathogenicity.

Lim CJJ et al. · Current microbiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2026PMID 41624108

Macroid Formation in Salmacina stellaebayensis n. sp. From Mauritania's Baie de l'Étoile With New Insights on Mitogenome Evolution in Serpulidae (Annelida).

Cremer et al. · Ecology and evolution

Added to ASH registry: 2026-05-28

Clinical Trials2026PMID 41980793

Myeloproliferative neoplasm as a cause of splanchnic vein thrombosis

Abboud B et al. · BMJ case reports

Added to ASH registry: 2026-05-28

Genomics & Proteomics2026PMID 41834834

Notch signaling in leech neurogenesis: expression patterns and functional insights in the Glossiphoniid leech.

Jeong et al. · Animal cells and systems

Added to ASH registry: 2026-05-28

Genomics & Proteomics2026PMID 40915965

Precision plant epigenome editing: what, how, and why

Leech et al. · Trends in plant science

Added to ASH registry: 2026-05-28

Clinical Trials2026PMID 41521091

Rationalizing thrombophilia screening in children: Insights from a 2019 retrospective study at a tertiary care hospital

Leleu M et al. · Archives de pediatrie : organe officiel de la Societe francaise de pediatrie

Added to ASH registry: 2026-05-28

Genomics & Proteomics2026PMID 41273385

Reflections on Model Species in Evolutionary Developmental Biology

Love et al. · Results and problems in cell differentiation

Added to ASH registry: 2026-05-28

Clinical Trials2026PMID 42088147

Regional citrate anticoagulation for renal replacement therapy during venovenous ECMO: A randomized crossover pilot study

Giani M et al. · Annals of intensive care

Added to ASH registry: 2026-05-28

Salivary Pharmacology2026PMID 42102583

Thrombin generation and the pharmacodynamics of parenteral anticoagulants.

Shaw JR et al. · Pharmacological reviews

Added to ASH registry: 2026-05-28

Genomics & Proteomics2026PMID 41810794

Tissue-level Consequences of Segmental Abnormalities in Hirudo verbana: A Morphological and Histological Approach

Tozak et al. · Turkiye parazitolojii dergisi

Added to ASH registry: 2026-05-28

Genomics & Proteomics2026PMID 41814161

Transcriptomic analysis of three annelid species: looking for markers of positional information.

Platova et al. · BMC genomics

Added to ASH registry: 2026-05-28

Genomics & Proteomics2026PMID 41956937

Transcriptomic classification and clinicopathologic correlation of hepatocellular neoplasms with steatotic features in non-cirrhotic livers

Zhu LC et al. · Pathology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2026PMID 41751895

Unmet Needs and Challenges in Cancer-Associated Venous Thromboembolism

Nusrat S et al. · International journal of molecular sciences

Added to ASH registry: 2026-05-28

Genomics & Proteomics2026PMID 41765218

Anticoagulant peptide LR from Whitmania pigra ameliorates cerebral ischemia-reperfusion injury

Liu R et al. · Brain research

Added to ASH registry: 2026-05-27

Genomics & Proteomics2026PMID 41933600

Construction of Corynebacterium glutamicum for efficient secretion and production of recombinant proteins using the technology of ARTP mutagenesis and fluorescen activated droplet microfluidic screening

Liu X et al. · Bioresource technology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2026PMID 41594695

Duplication of the Antistasin-Like Structure Resulted in a New Anticoagulant Protein in the Medicinal Leech

Brovina KA et al. · Biomolecules

Added to ASH registry: 2026-05-27

Genomics & Proteomics2026PMID 41573256

ERGA-BGE reference genome of a once neglected freshwater haematophagous European medicinal leech

Manzano-Marin A et al. · Open research Europe

Added to ASH registry: 2026-05-27

Genomics & Proteomics2026PMID 41573256

ERGA-BGE reference genome of Hirudo verbana, a once neglected freshwater haematophagous European medicinal leech

Manzano-Marin A et al. · Open research Europe

Added to ASH registry: 2026-05-27

Genomics & Proteomics2026PMID 42177920

Hirudin suppresses ovarian cancer cell proliferation and glycolysis through inhibiting the NF-B/HK3 axis

Guo Y et al. · Gene

Added to ASH registry: 2026-05-27

Genomics & Proteomics2026PMID 42092413

Identification and characterization of WpDestabilase, a novel destabilase from the salivary glands of Whitmania pigra

Huang B et al. · Protein expression and purification

Added to ASH registry: 2026-05-27

Genomics & Proteomics2026PMID 41622356

Mining anticoagulant peptides from Poecilobdella manillensis by peptidomics analysis

Zheng HX et al. · Natural products and bioprospecting

Added to ASH registry: 2026-05-27

Salivary Pharmacology2026PMID 41828340

Molecular Insights into Leech-Derived Bioactive Compounds: Biochemical Mechanisms and Therapeutic Potential

Raghavi S et al. · International journal of molecular sciences

Added to ASH registry: 2026-05-27

Drug Development2026PMID 41817943

Recombinant Fusion Protein Composed of Hirudin and Annexin A5 Shows Anti-Coagulant Activity In Vitro

Dong H et al. · Applied biochemistry and biotechnology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2026PMID 41653280

The great diversity: monomeric and oligomeric hirudins, hirudin-like factors and decorsins in the Asian medicinal leeches Hirudo nipponia and Hirudo tianjinensis

Kalatehjari P et al. · Parasitology research

Added to ASH registry: 2026-05-27

Genomics & Proteomics2026PMID 41981479

Gut microbiota and metabolic function in leeches with distinct feeding niches

Tong X, Yang D, Cao X et al. · BMC microbiology

Added to ASH registry: 2026-05-26

Salivary Pharmacology2026PMID 41828340

Molecular Insights into Leech-Derived Bioactive Compounds: Biochemical Mechanisms and Therapeutic Potential

Raghavi S, Deva Darshini B, Saravanan KM, Anbarasu K · International journal of molecular sciences

Added to ASH registry: 2026-05-26

Clinical Trials2026PMID 41507963

Effects of hirudotherapy on liver functions, lipid profile, and insulin sensitivity in rats with metabolic syndrome

Bilden A et al. · BMC complementary medicine and therapies

Added to ASH registry: 2026-03-18

Clinical Trials2026PMID 41743152

Efficacy and Safety of Hirudotherapy for Improving Sperm Quality Parameters in Male Infertility: A Randomized Controlled Trial

Abtahi-Forooshani M et al. · Health science reports

Added to ASH registry: 2026-03-18

2025

74 articles
Genomics & Proteomics2025PMID 40020462

Argatroban and Menadione exert protective effects in ultraviolet-irradiated skin inflammation: A transcriptomic analysis based on identification of iron overload related biomarkers

Lv et al. · International immunopharmacology

Added to ASH registry: 2026-05-29

Genomics & Proteomics2025PMID 40660120

A genome resource for the marine annelid Platynereis spp.

Mutemi et al. · BMC genomics

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 40173960

A new species of Odontobdella Oka, 1923 (Erpobdelliformes: Salifidae), a macrophagous terrestrial leech from Central China

Yin et al. · Zootaxa

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 41448295

A novel bacteriophage pAEh1 for controlling Aeromonas hydrophila infection in aquaculture.

Jiang S et al. · Fish & shellfish immunology

Added to ASH registry: 2026-05-28

Clinical Trials2025PMID 41384770

Anticoagulation and hemostasis in the extracorporeal membrane oxygenation patient.

Saura O et al. · Current opinion in anaesthesiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 40078478

Comparative genomics of three non-hematophagous leeches (Whitmania spp.) with emphasis on antithrombotic biomolecules

Zhao et al. · Frontiers in genetics

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 39729945

Comparative proteomic analysis reveals the response mechanism of freshwater leech (Whitmania pigra) under heat-stress challenge

Wang et al. · Comparative biochemistry and physiology. Part D, Genomics & proteomics

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 40862623

Comparative single-cell genomics of two uncultivated Naegleria species harboring Legionella cobionts

McGowan et al. · mSphere

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 40100768

Comprehensive Genomic Analysis of Antimicrobial Resistance in.

Chen YW et al. · Microbial drug resistance (Larchmont, N.Y.)

Added to ASH registry: 2026-05-28

Clinical Trials2025PMID 40847481

Effect of PCSK9 Inhibition With Alirocumab in Patients With Probable Familial Hypercholesterolemia or Type III Hyperlipoproteinemia: Results From the ODYSSEY OUTCOMES Trial

Geba GP et al. · Journal of the American Heart Association

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 40586497

Environmental and biological interactions of Hepatitis B virus in leeches - a molecular investigation

Bilden et al. · Annals of agricultural and environmental medicine : AAEM

Added to ASH registry: 2026-05-28

Clinical Trials2025PMID 40023651

Extended treatment of venous thromboembolism with reduced-dose versus full-dose direct oral anticoagulants in patients at high risk of recurrence: a non-inferiority, multicentre, randomised, open-label, blinded endpoint trial

Couturaud F et al. · Lancet (London, England)

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 40766313

Feed status and skin injury modulate immunopathology, global gene expression, and survival in channel catfish during virulentinfection

Soku YK et al. · Frontiers in immunology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 40675503

First report of natural co-infections and protein profile of Indian major carp, Labeorohita.

Pinto N et al. · Microbial pathogenesis

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 41597555

Genome-Resolved Co-Infection byandsp. in Koi Carp: A Zoonotic Risk for Aquarists.

Tasci G et al. · Microorganisms

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 40920301

Genomic insights, determination of quorum quenching potential of a beta-lactamase enzyme from Chromohalobacter sp. strain D23 against Aeromonas hydrophila and molecular docking study.

Ghosh D et al. · International microbiology : the official journal of the Spanish Society for Microbiology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 40874053

Identification of anstrain as a new mosquito pathogen.

Wehbe R et al. · Frontiers in cellular and infection microbiology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 41078496

Isolation and genomic analysis of phage BUCT551 against drug-resistant.

Han P et al. · Frontiers in veterinary science

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 41594064

Isolation, Characterization, and Evaluation of a Lytic Jumbo Phage Z90 Againstin American Eels ().

Zhang M et al. · Antibiotics (Basel, Switzerland)

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 39490713

Leech granules inhibit ferroptosis and alleviate renal injury in mice with diabetic kidney disease

Cao et al. · Journal of ethnopharmacology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 40139596

Molecular characterization and immunological functions of the antimicrobial peptide theromacin from razor clam Sinonovacula constricta.

Hu H et al. · International journal of biological macromolecules

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 39839334

Molecular Insights Into the Sensory Adaption of the Cave-Dwelling Leech Sinospelaeobdella wulingensis to the Karst Cave Environment

Wen et al. · Ecology and evolution

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 41190312

Predictive Distribution Modeling of the Medicinal Leech Hirudo verbana Carena, 1820 (Hirudinea, Hirudinidae) in Sicily: Implications for Conservation

Liuzzo et al. · Ecology and evolution

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 41597561

Probiotic Properties In Vitro ofFJAT-57093 with Antibacterial Activity Against the Aquatic Pathogen.

Chen Y et al. · Microorganisms

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 40744271

Proteomics reveals the role of the EamB transporter from Aeromonas hydrophila LP-2 in biofilm formation.

Xu Q et al. · Journal of proteomics

Added to ASH registry: 2026-05-28

Salivary Pharmacology2025PMID 40442481

Rapid clearance of achiral small-molecule drugs using de novo-designed proteins and their cyclic and mirror-image variants.

Chen G et al. · Nature biomedical engineering

Added to ASH registry: 2026-05-28

Clinical Trials2025PMID 41238194

Survey on current practice in thrombophilia testing: from phenotype to genotype. Communication from the SSC of the ISTH

Van Laer C et al. · Journal of thrombosis and haemostasis : JTH

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 40135052

Susceptibility ofsubsp.bacteria from French farmed trout to antibiotics commonly used in fish farming, and attempt to set epidemiological cut-off values.

Rostang A et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-28

Salivary Pharmacology2025PMID 39937537

SYNONYMIZATION OF PLACOBDELLA PICTA (VERRILL, 1872) (HIRUDINEA: GLOSSIPHONIIDAE) WITH DESCRIPTIONS OF TWO NEW SPECIES REVEALED BY MOLECULAR SPECIES DELIMITATION.

Phillips AJ et al. · The Journal of parasitology

Added to ASH registry: 2026-05-28

Salivary Pharmacology2025PMID 41085213

Targeting thrombin with hirudin alleviates paraquat-induced pulmonary fibrosis via the PAR-1-mediated TGF-β1 pathway.

Hu X et al. · Histology and histopathology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 40771652

The chromosomal genome sequence of the marine leech, Branchellion lobata Moore, 1952 and its associated microbial metagenome sequences

Goffredi et al. · Wellcome open research

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 39673176

The Rich Evolutionary History of the Reactive Oxygen Species Metabolic Arsenal Shapes Its Mechanistic Plasticity at the Onset of Metazoan Regeneration.

Vullien et al. · Molecular biology and evolution

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 41126293

The role of ABCB1 and CES1 genotypes on the efficacy and safety of dabigatran: a systematic review and meta-analysis

Aldiban et al. · Human genomics

Added to ASH registry: 2026-05-28

Clinical Trials2025PMID 41479579

Thrombotic risk in hepatitis C: Interplay between hepatic dysfunction, viral-driven inflammation, and cardiovascular consequences

Zohery M et al. · World journal of virology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 39963574

Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective

Mortazavi et al. · BioImpacts : BI

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 41070122

Urban wastewater overflows as hotspots for dissemination of bacteria producing extended-spectrum β-lactamases and carbapenemases in the Suquía River, Argentina.

Ruiz SE et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 40899333

Whole-Genome Sequencing Analysis of the Multidrug-ResistantStrain AC1520 Isolated from a Patient with Urinary Tract Infection.

Xie T et al. · Microbial drug resistance (Larchmont, N.Y.)

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2025PMID 40071199

Whole-genome sequencing-based species classification, multilocus sequence typing, and antibiotic resistance mechanisms of the clinicalcomplex.

Lu J et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2025PMID 40807359

A novel integrated strategy for discovering absorbable anticoagulant bioactive peptides: a case study on leech protein hydrolysates

Fang KX et al. · Molecules

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 41041396

Application of invertebrate-derived DNA barcoding (iDNA) in blood sucking leeches from West Sumatra

Irawan AD et al. · Ecology and evolution

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 40461966

Chromosome-level genome assembly and anticoagulant protein annotation of the buffalo leech Hirudinaria bpling (Hirudinea: Hirudinidae)

Khan MS et al. · BMC genomics

Added to ASH registry: 2026-05-27

Drug Development2025PMID 40461966

Chromosome-level genome assembly and anticoagulant protein annotation of the buffalo leech Hirudinaria bpling (Hirudinea: Hirudinidae)

Khan MS et al. · BMC Genomics

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 41469844

Comparative genomics suggests extensive antithrombotic gene expansion in Haemadipsa yanyuanensis

Lin Y et al. · BMC genomics

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 41300784

Comparative study of hirustasin superfamily gene expression in two medicinal leeches

Sun et al. · Genes

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 40906077

Comparative Study of Lefaxin Family in Two Asian Leeches:and

Ye T et al. · Biology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 41073556

Complete cox1 gene and ITS sequence of Hirudinaria manillensis and molecular evolution analysis

Wang W et al. · Scientific reports

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 40578279

Corrigendum to "Sonorheometry parameters during dabigatran reversal with idarucizumab for major bleeding" [The Journal of Pharmacology and Experimental Therapeutics 392 (2025) 103605]

Teissandier D et al. · The Journal of pharmacology and experimental therapeutics

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 41357958

Description of two new species of freshwater leeches of the genus Theromyzon (Hirudinea, Glossiphoniidae) from Mexico

Torres-Carrera G et al. · ZooKeys

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 39799216

Development of a mitochondrial mini-barcode and its application in metabarcoding for identification of leech in traditional Chinese medicine

Shi C et al. · Scientific Reports

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 41568254

ERGA-BGE reference genome of the lineid heteronemertean(Pilidiophora, Nemertea)

Verdes A et al. · Open research Europe

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 40126700

Extracorporeal membrane oxygenation (ECMO) in pediatric congenital heart disease: a comprehensive review

Faheem MSB et al. · The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 40427706

Genetic variation and gene expression of the antimicrobial peptide macins in Asian Buffalo Leech

Yu Y et al. · Biology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 41198932

Hirudins and fenestrins of the African medicinal leech Asiaticobdella fenestrata

Schulz L et al. · Parasitology research

Added to ASH registry: 2026-05-27

Salivary Pharmacology2025PMID 40725149

Identification and Screening of Novel Antimicrobial Peptides from Medicinal Leech via Heterologous Expression in E. coli

Serebrennikova M et al. · International journal of molecular sciences

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 40424620

Intravenous Dabigatran for Anticoagulation during Cardiopulmonary Bypass in a Sheep Model

Nadtochiy SM et al. · Anesthesiology

Added to ASH registry: 2026-05-27

Salivary Pharmacology2025PMID 40728968

Leech Extract Enhances the Pro-Angiogenic Effects of Endothelial Cell-Derived Exosomes in a Mouse Model of Ischemic Stroke

Cao Y et al. · Current issues in molecular biology

Added to ASH registry: 2026-05-27

Safety & Infection Control2025PMID 40284753

Microbiota Dynamics: A Key Factor in Hirudotherapy-Related Infections?

Karasartova D et al. · Microorganisms

Added to ASH registry: 2026-05-27

Salivary Pharmacology2025PMID 40107525

Molecular cloning and functional analysis of a destabilase from Hirudinaria manillensis

Gao T et al. · Protein expression and purification

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 41303498

Monomeric and Oligomeric Decorsins of the Asian Medicinal Leech

Tolksdorf C et al. · International journal of molecular sciences

Added to ASH registry: 2026-05-27

Drug Development2025PMID 41402686

Multi-target anticoagulant regulation by peptides from medicinal leeches: a unique natural strategy

Shi et al. · Pharmaceutical research

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 40064243

Neuroprotective effects of hirudin against cerebral ischemia-reperfusion injury via inhibition of CCL2-mediated ferroptosis and inflammatory pathways

Liao J et al. · Brain Res Bull

Added to ASH registry: 2026-05-27

Drug Development2025PMID 40916000

Production and functional characteristics of a novel hirudin variant with better anticoagulant activities than bivalirudin

Ge P et al. · Journal of enzyme inhibition and medicinal chemistry

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 41463289

Production, Purification, and Characterization of a Novel Cysteine-Rich Anticoagulant from the Medicinal Leech and the Functional Role of Its Disulfide Bonds

Manuvera VA et al. · Biomolecules

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 41131974

Taxonomic update and DNA barcoding of Tunisian nasal leeches (Annelida: Hirudiniformes; Praobdellidae): confirming Limnatis nilotica and revealing a second Limnatis species in North Africa

Ben Ahmed R et al. · Invertebrate Systematics

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 41131974

Taxonomic update and DNA barcoding of Tunisian nasal leeches: confirming Limnatis nilotica and revealing a second species

Ben Ahmed R et al. · Invertebrate systematics

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 40594022

The development and application of mini-barcodes from mitochondrial DNA for identifying medicinal leeches from traditional medicines

Liu Y et al. · Scientific reports

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 41660135

The genome sequence of the freshwater leech Erpobdella octoculata (Linnaeus, 1758) (Hirudinida: Erpobdellidae)

Skipp SJ et al. · Wellcome open research

Added to ASH registry: 2026-05-27

Safety & Infection Control2025PMID 40725461

The problem of the presence of DNA in cosmetic and medicinal products obtained from animals on the CITES list

Figura A et al. · Genes

Added to ASH registry: 2026-05-27

Genomics & Proteomics2025PMID 40165593

Ultrastructural Architecture and Morphological Examination of Hirudo verbana (Annelida, Hirudinea)

Selviler Sizer S et al. · Microscopy research and technique

Added to ASH registry: 2026-05-27

Drug Development2025PMID 40922112

Discovery of a Thrombin-Targeting Anticoagulant Peptide From Whitmania pigra via a 'Computation-Guided Experimentation' Strategy

Hua YT et al. · Journal of peptide science : an official publication of the European Peptide Society

Added to ASH registry: 2026-05-26

Safety & Infection Control2025PMID 40284753

Microbiota Dynamics: A Key Factor in Hirudotherapy-Related Infections?

Karasartova D, Arslan-Akveran G, Sensoz S, Mumcuoglu KY, Taylan-Ozkan A · Microorganisms

Added to ASH registry: 2026-05-26

Genomics & Proteomics2025PMID 39799216

Development of a mitochondrial mini-barcode and its application in metabarcoding for identification of leech in traditional Chinese medicine

Shi C et al. · Scientific reports

Added to ASH registry: 2026-03-18

Drug Development2025PMID 40268196

Leech bionic Hirudin fusion protein prodrug loaded microneedles for long-term inhibition of thrombosis

Tian X et al. · Journal of controlled release : official journal of the Controlled Release Society

Added to ASH registry: 2026-03-18

Drug Development2025PMID 39657884

Novel drug delivery systems for hirudin-based product development and clinical applications

Mo L et al. · International journal of biological macromolecules

Added to ASH registry: 2026-03-18

2024

57 articles
Genomics & Proteomics2024PMID 38397154

A Chromosome-Level Genome Assembly of the Non-Hematophagous Leech Whitmania pigra (Whitman 1884): Identification and Expression Analysis of Antithrombotic Genes

Liu et al. · Genes

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 38948846

A genome resource for the marine annelid Platynereis dumerilii.

Mutemi et al. · bioRxiv : the preprint server for biology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2024PMID 39687168

A novel in-silico approach to design a multiepitope peptide as a vaccine candidate for.

SobhZahedi M et al. · Heliyon

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 39646772

A revision of Chinese endemic Neptis hesione Leech, 1890 with a new species described from Hainan Island (Lepidoptera, Nymphalidae)

Li et al. · Zootaxa

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 38798472

Acceleration of genome rearrangement in clitellate annelids

Schultz et al. · bioRxiv : the preprint server for biology

Added to ASH registry: 2026-05-28

Salivary Pharmacology2024PMID 38826540

Allosteric Modulation of Thrombin by Thrombomodulin: Insights from Logistic Regression and Statistical Analysis of Molecular Dynamics Simulations.

Wu D et al. · ACS omega

Added to ASH registry: 2026-05-28

Clinical Trials2024PMID 38926082

Anticoagulation reversal (vitamin K, prothrombin complex concentrates, idarucizumab, andexanet-α, protamine).

Bekka E et al. · British journal of clinical pharmacology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 39639374

Bioactive peptides and proteins for tissue repair: microenvironment modulation, rational delivery, and clinical potential

Hao et al. · Military Medical Research

Added to ASH registry: 2026-05-28

Safety & Infection Control2024PMID 39372357

Characterization and Genome Analyses of the Novel Phages P2 and vB_AhydM-H1 Targeting.

Nagar V et al. · PHAGE (New Rochelle, N.Y.)

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 38699363

Characterization of a Fatty Acid Amide Hydrolase (FAAH) in Hirudo verbana

Kabeiseman et al. · Research square

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2024PMID 39038632

Comparative genomics of IncQ1 plasmids carrying blavariants from clinical and environmental sources in Brazil.

Conte D et al. · Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

Added to ASH registry: 2026-05-28

Clinical Trials2024PMID 38821513

Cost-effectiveness of enoxaparin versus aspirin in the prevention of venous thromboembolism after total hip or knee arthroplasty: an analysis from the CRISTAL cluster-randomized trial

et al. · The bone & joint journal

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 38842327

Discovery of a novel symbiotic lineage associated with a hematophagous leech from the genus

Sosa-Jiménez VM et al. · Microbiology spectrum

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 39419922

Effect control of novel Hirudinaria manillensis extract on the molecular regulation of EGFR gene and its protein expression in HeLa cells

Shannan et al. · Molecular biology reports

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 39744405

Emergingspp. infections in Europe: characterization of human clinical isolates from German patients

Schwartz K et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 38491315

In vitro anticancer activity of Hirudinaria manillensis methanolic extract and its validation using in silico molecular docking approach

Zeebul et al. · Medical oncology (Northwood, London, England)

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2024PMID 39563500

Infection Status, Etiological Analysis ofspp. in Foodborne Diarrhea Patients from 2019 to 2023 in Wenzhou.

Lou H et al. · Foodborne pathogens and disease

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 38970720

Molecular based identification and phylogenetic relationship of the leech Hirudinaria manillensis from India by using mitochondrial cytochrome c oxidase subunit I gene

Shannan et al. · Molecular biology reports

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2024PMID 38184574

Molecular characterization and antibiotics resistance of Aeromonas species isolated from farmed African catfish Clarias gariepinus Burchell, 1822.

Adah DA et al. · BMC veterinary research

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2024PMID 38912216

Molecular Epidemiological Characteristics of Carbapenem Resistantfrom Hospital Wastewater.

Zhang Q et al. · Infection and drug resistance

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2024PMID 39498999

Molecular Identification, Histopathology and Antibiotic Susceptibility Profiling of Aeromonas veronii Isolated from Oreochromis niloticus in Bangladesh.

Bari SM et al. · Veterinary medicine and science

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2024PMID 39043820

Novel lytic bacteriophage AhFM11 as an effective therapy against hypervirulent Aeromonas hydrophila.

Muliya Sankappa N et al. · Scientific reports

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2024PMID 38783344

Phenotypic and genotypic analysis of antimicrobial resistance and population structure of gastroenteritis-related Aeromonas isolates.

Sagas D et al. · Annals of clinical microbiology and antimicrobials

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 38312682

Proteomic analysis of crocodile white blood cells reveals insights into the mechanism of the innate immune system

Tankrathok A et al. · Heliyon

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 39441552

Targeted Genome Mining Facilitates the Discovery of a Promiscuous, Hyperthermostable Amidase from Thermovenabulum Gondwanense with Notable Nylon-Degrading Capacity

Hoffman ER et al. · Angewandte Chemie (International ed. in English)

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2024PMID 39437925

Temporal dynamics of extended-spectrum β-lactamase-producing Escherichia coli and carbapenemase-producing Gram-negative bacteria in hospital wastewater.

Tanabe M et al. · The Science of the total environment

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 38480301

Terrestrial predatory leeches of the genus Orobdella (Hirudinea: Erpobdelliformes: Orobdellidae) endemic to the Southern Russian Far East: a new species of the genus from Primorsky Krai, Russia

Nakano et al. · Zootaxa

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 39035273

The dental implant survival rate in 18 patients with post-operation revolutionary jaw reconstruction using free fibular flap, dental implants, and overdentures

Ko et al. · Journal of dental sciences

Added to ASH registry: 2026-05-28

Clinical Trials2024PMID 38331787

Thrombosis-related characteristics of pregnant women with antithrombin deficiency, protein C deficiency and protein S deficiency in Japan.

Kobayashi T et al. · Thrombosis journal

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2024PMID 39457397

Transcriptomic and Proteomic Analyses of the Immune Mechanism in Pathogenetic and Resistant Chinese Soft-Shelled Turtle () Infected with.

Ge L et al. · Genes

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 39214080

Unexplored microbial diversity from 2,500 food metagenomes and links with the human microbiome

Carlino et al. · Cell

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 36899149

Why study sleep in flatworms?.

Omond et al. · Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2024PMID 39141777

Annelid Comparative Genomics and the Evolution of Massive Lineage-Specific Genome Rearrangement in Bilaterians

Lewin TD et al. · Molecular biology and evolution

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 39093361

Characterization of a Fatty Acid Amide Hydrolase (FAAH) in Hirudo Verbana

Kabeiseman E et al. · Neurochemical research

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 39537640

Chromosome-level genome assembly of the cave leech Sinospelaeobdella cavatuses (Hirudinea: Haemadipsidae)

Yao B et al. · Scientific data

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 38750856

Comparative genomics of two Asian medicinal leeches Hirudo nipponia and Hirudo tianjinensis

Zhao et al. · International journal of biological macromolecules

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 38424269

Dynamic relationship among extracellular matrix and body wall cells in Hirudo verbana morphogenesis

Pulze L et al. · Cell and tissue research

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 38827288

Exploring species diversity and phylogenetic relationship within Suborder Erpobdelliformes

Liu Y et al. · PeerJ

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 39649550

Gut microbiota participates and remodels host metabolism: from treating patients to treating their gut flora

Han S et al. · World journal of gastroenterology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 39537753

Hepatocellular senescence induces multi-organ senescence and dysfunction via TGF

Kiourtis C et al. · Nature cell biology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 39570434

Identification and functional characterization of multiple haemadins and an oligomeric decorsin in the Asian land leech Haemadipsa interrupta

Müller C et al. · Parasitol Res

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 38700436

Molecular phylogeny of the leech genus Pontobdella with notes on Pontobdella californiana and Pontobdella macrothela

Ruiz-Escobar F et al. · The Journal of parasitology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 39432187

Morphological data and DNA barcoding reveal the presence of the alien freshwater leech Helobdella octatestisaca (Hirudinida: Glossiphoniformes) in North Africa (Tunisia)

Ben Ahmed R et al. · Molecular Biology Reports

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 39432187

Morphological data and DNA barcoding reveal the presence of the alien freshwater leech Helobdella octatestisaca in North Africa

Ben Ahmed R et al. · Molecular biology reports

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 38702587

Not that many leech species after all: Myzobdella lugubris and Myzobdella patzcuarensis are the same species

Torres-Carrera G et al. · Systematic parasitology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 40329956

Rapid molecular species identification of mammalian scat samples using nanopore adaptive sampling

Frank LE et al. · Journal of mammalogy

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 38923974

Starvation-induced changes in the proteome and transcriptome of the salivary glands of leech (Hirudo nipponia)

Cai M et al. · PLoS One

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 38540342

Transcriptomic Profiling at the Maternal-to-Zygotic Transition in Leech

Hsaio S et al. · Genes

Added to ASH registry: 2026-05-27

Genomics & Proteomics2024PMID 38677578

Exploring a Hirudin variant from nonhematophagous leeches: Unraveling full-length sequence, alternative splicing, function, and potential as a novel anticoagulant polypeptide

Yi X et al. · Journal of ethnopharmacology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2024PMID 38923974

Starvation-induced changes in the proteome and transcriptome of the salivary glands of leech (Hirudo nipponia)

Cai M, Shen H, Xing Y, Wang W, Guan F, Luo Y · PLoS one

Added to ASH registry: 2026-05-26

Genomics & Proteomics2024PMID 38372102

18s rDNA characterization and morphological investigation of the medicinal leech Hirudo medicinalis from Felaw Pond

Jawdat Bilal S · Cellular and molecular biology (Noisy-le-Grand, France)

Added to ASH registry: 2026-03-18

Genomics & Proteomics2024PMID 38387485

Correction: Unusual Case of Bilateral Combined Retinal Vein and Artery Occlusion - Presumably Due to Leech Therapy by Hirudo Medicinalis

Ağın A et al. · Klinische Monatsblatter fur Augenheilkunde

Added to ASH registry: 2026-03-18

Genomics & Proteomics2024PMID 39540973

Diversity of hirudin and hirudin-like factor genes in the North-African medicinal leech, Hirudo troctina

Ahmed R, Abilov A, Müller C · Parasitology research

Added to ASH registry: 2026-03-18

Salivary Pharmacology2024PMID 39671012

Immunomodulatory effects of medicinal leech saliva extract on in vitro activated macrophages

Ayhan H et al. · Immunologic research

Added to ASH registry: 2026-03-18

Genomics & Proteomics2024PMID 38241814

New anticoagulant protein from medicinal leech

Manuvera V et al. · Biochemical and biophysical research communications

Added to ASH registry: 2026-03-18

Genomics & Proteomics2024PMID 38158145

Transcriptomic profiling and the first spatial expression analysis of candidate genes in the salivary gland of the East Asian medicinal leech, Hirudo nipponia

Kim J et al. · Developmental and comparative immunology

Added to ASH registry: 2026-03-18

Drug Development2024PMID 37860993

Tyrosine phosphorylation of recombinant hirudin increases affinity to thrombin and antithrombotic activity

Volkova A, Semenyuk P · Proteins

Added to ASH registry: 2026-03-18

2023

47 articles
Genomics & Proteomics2023PMID 37522602

A New Species of Branchellion (Hirudinea: Piscicolidae) Parasitizing the Gills of Short-Tail Stingrays (Batoidea: Dasyatidae) from the West Pacific

Jimi et al. · Zoological science

Added to ASH registry: 2026-05-28

Clinical Trials2023PMID 37175682

An Exploratory Study Using Next-Generation Sequencing to Identify Prothrombotic Variants in Patients with Cerebral Vein Thrombosis

Kramer RA et al. · International journal of molecular sciences

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2023PMID 38156048

Clinical Features, Genome Epidemiology, and Antimicrobial Resistance Profiles ofspp. Causing Human Infections: A Multicenter Prospective Cohort Study.

Sakurai A et al. · Open forum infectious diseases

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2023PMID 36707480

Diversity and antibiograms of bacteria isolated from cutaneous leishmaniasis wounds in the Nkwanta South District of Ghana.

Yeboaa C et al. · Archives of microbiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 37690114

Evolution of an Alternative Genetic Code in the Providencia Symbiont of the Hematophagous Leech Haementeria acuecueyetzin

Manzano-Marín A et al. · Genome biology and evolution

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 37968990

Harnessing the Power of Artificial Intelligence: Revolutionizing Free Flaps Monitoring in Head and Neck Tumor Treatment

Bassani et al. · Critical reviews in oncogenesis

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2023PMID 36671285

Hiding in Plain Sight: Characterization ofSpecies Isolated from a Recreational Estuary Reveals the Carriage and Putative Dissemination of Resistance Genes.

Canellas ALB et al. · Antibiotics (Basel, Switzerland)

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2023PMID 37920263

Identification and characterization of a novel 6'-N-aminoglycoside acetyltransferase AAC(6')-Va from a clinical isolate of.

Zhang G et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 37243257

In Silico and In Vitro Evaluation of Some Amidine Derivatives as Hit Compounds towards Development of Inhibitors against Coronavirus Diseases.

Hassan AHE et al. · Viruses

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 36725208

Integrated molecular approaches for fermented food microbiome research

Walsh et al. · FEMS microbiology reviews

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 41131932

Lumping three nominal species into one: taxonomic revision of amphibian parasitic leeches of Torix in Far East Asia (Hirudinea: Glossiphoniidae)

Kambayashi et al. · Invertebrate systematics

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 37193718

Mitogenomic phylogenetic analyses provide novel insights into the taxonomic problems of several hesperiid taxa (Lepidoptera: Hesperiidae)

Zhu et al. · Scientific reports

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 37375085

Molecular Phylogenies of Leeches and Haemoparasites Infecting Freshwater Turtles in Aquatic Ecosystems of Northern Africa Suggest Phylogenetic Congruence between Placobdella costata Sensu Lato and Haemogregarina stepanowi Sensu Lato

Verneau et al. · Microorganisms

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 36482101

Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae

Thompson et al. · Nature medicine

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 36997443

Platelet function in neonates and children.

Van Den Helm et al. · Thrombosis research

Added to ASH registry: 2026-05-28

Clinical Trials2023PMID 37373857

Pneumatic Compression Combined with Standard Treatment after Total Hip Arthroplasty and Its Effects on Edema of the Operated Limb and on Physical Outcomes: A Pilot Clinical Randomized Controlled Study

Carnevale Pellino V et al. · Journal of clinical medicine

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 36754342

Proteases and their inhibitors involved in Schistosoma mansoni egg-host interaction revealed by comparative transcriptomics with Fasciola hepatica eggs

Peterkova et al. · International journal for parasitology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2023PMID 36604972

Proteomics analysis reveals that CirA in Aeromonas hydrophila is involved in nutrient uptake.

Song Q et al. · Environmental microbiology

Added to ASH registry: 2026-05-28

Clinical Trials2023PMID 37675985

Pulmonary embolism following an undiagnosed Paget-Schroetter syndrome: a case report and review of the literature

Negrão Pantaleão A et al. · The Physician and sportsmedicine

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 37810610

The complete mitochondrial genome and phylogenetic analysis of Polythlipta liquidalis Leech, 1889 (Crambidae: spilomelinae)

Yang et al. · Mitochondrial DNA. Part B, Resources

Added to ASH registry: 2026-05-28

Salivary Pharmacology2023PMID 36833315

The Complete Mitochondrial Genome of(Annelida: Hirudinea: Glossiphoniidae).

Zhu X et al. · Genes

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 38813549

The genome sequence of the fish leech, Piscicola geometra (Linnaeus, 1761)

Doe et al. · Wellcome open research

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2023PMID 37214649

Whole Genome Sequence of a Novel Bacteriophage APT65 Infecting.

Cebeci A et al. · PHAGE (New Rochelle, N.Y.)

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 37173388

Whole spectrum of Aeromonas hydrophila virulence determinants and the identification of novel SNPs using comparative pathogenomics

Abdella B et al. · Scientific reports

Added to ASH registry: 2026-05-28

Genomics & Proteomics2023PMID 36968539

Analysis of Heparin Samples by Attenuated Total Reflectance Fourier-Transform Infrared Spectroscopy in the Solid State

Devlin AJ et al. · ACS central science

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 38047014

Buried treasure in a public repository: mining mitochondrial genes of 32 annelid species from sequence reads deposited in the Sequence Read Archive

Kobayashi G et al. · PeerJ

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 37133542

Characterization of the natural peptidome of four leeches by integrated proteogenomics and pseudotargeted peptidomics

Liu X et al. · Analytical and bioanalytical chemistry

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 37697397

Chromosome-level Dinobdella ferox genome provided a molecular model for its specific parasitism

Gao JW et al. · Parasites & vectors

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 36975989

Chromosome-Level Genome Assembly ofLeech, 1889 (Lepidoptera: Papilionidae)

Pan Z et al. · Insects

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 36973525

Cloning, characterization, and heterologous expression of a candidate hirudin gene from the salivary gland transcriptome of Hirudo nipponia

Shi P et al. · Scientific reports

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 37069497

Division of developmental phases of freshwater leech Whitmania pigra and key genes related to neurogenesis revealed by whole genome and transcriptome analysis

Liu J et al. · BMC genomics

Added to ASH registry: 2026-05-27

Salivary Pharmacology2023PMID 37708351

Exploiting Chemical Protein Synthesis to Study the Role of Tyrosine Sulfation on Anticoagulants from Hematophagous Organisms

Maxwell JWC et al. · Accounts of chemical research

Added to ASH registry: 2026-05-27

Salivary Pharmacology2023PMID 37446275

Isolation and characterization of poeciguamerin, a peptide with dual analgesic and antithrombotic activity from leech salivary glands

Wang et al. · International journal of molecular sciences

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 36713196

Marine vampires: Persistent, internal associations between bacteria and blood-feeding marine annelids and crustaceans

Goffredi SK et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-27

Salivary Pharmacology2023PMID 36996929

Molecular cloning and functional analysis of HnSaratin from Hirudo nipponia

Cheng B et al. · Gene

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 37039117

Molecular mechanisms underlying hematophagia revealed by comparative analyses of leech genomes

Zheng J et al. · GigaScience

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 37422418

Motor neural networks in the leech

Szczupak L · Trends in neurosciences

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 38007222

Possible detection of physiological state disorders with the help of medicinal leeches Hirudo verbana

Aminov R · Annals of parasitology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 37659761

Quantitative proteomics based bioactive proteins discovery and quality control of medicinal leeches

Li FG et al. · Journal of ethnopharmacology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 38073545

Research progress of natural active compounds on improving podocyte function to reduce proteinuria in diabetic kidney disease

Gong L et al. · Renal failure

Added to ASH registry: 2026-05-27

Antimicrobial Resistance2023PMID 37833572

Role of Antimicrobial Peptides in Immunity of Parasitic Leeches

Kaygorodova IA · Doklady biological sciences

Added to ASH registry: 2026-05-27

Genomics & Proteomics2023PMID 38158145

Transcriptomic profiling and the first spatial expression analysis of candidate genes in the salivary gland of the East Asian medicinal leech, Hirudo nipponia

Kim JH et al. · Developmental and comparative immunology

Added to ASH registry: 2026-05-27

Salivary Pharmacology2023PMID 36918198

Intracerebral hirudin injection alleviates cognitive impairment and oxidative stress and promotes hippocampal neurogenesis in rats subjected to cerebral ischemia

Xia X et al. · Neuropathology : official journal of the Japanese Society of Neuropathology

Added to ASH registry: 2026-03-18

Genomics & Proteomics2023PMID 36586192

Protective efficacy of Eglin C from Hirudo medicinalis against Eimeria papillata-induced coccidiosis

Al-Sayed S et al. · Veterinary parasitology

Added to ASH registry: 2026-03-18

Drug Development2023PMID 38003011

Revisiting the Asian Buffalo Leech (

Liu Z et al. · Genes

Added to ASH registry: 2026-03-18

Genomics & Proteomics2023PMID 37095116

Structural insights into thrombolytic activity of destabilase from medicinal leech

Marin E et al. · Scientific reports

Added to ASH registry: 2026-03-18

Clinical Trials2023PMID 37768304

The effect of blood human, domestic and small laboratory animals on the viability and behavior of the medicinal leech

Aminov R · Annals of parasitology

Added to ASH registry: 2026-03-18

2022

60 articles
Antimicrobial Resistance2022PMID 35546572

-Harboring Aeromonas veronii from the Hospital Sewage Samples in China.

Yang C et al. · Microbiology spectrum

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 34863800

A new species of mammalian trypanosome, Trypanosoma (Megatrypanum) bubalisi sp. nov., found in the freshwater leech Hirudinaria manillensis

Su et al. · International journal for parasitology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35836684

A new species of medicinal leech in the genus Hirudo Linnaeus, 1758 (Hirudiniformes, Hirudinidae) from Tianjin City, China

Wang et al. · ZooKeys

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35430899

Cerebral Venous Sinus Thrombosis in Preterm Infants.

Christensen et al. · Stroke

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35005228

Characterization of the complete mitochondrial genome of Haemadipsa tianmushana Song 1977 (Hirudiniformes, Haemadipsidae) and its phylogenetic analysis.

Lu et al. · Mitochondrial DNA. Part B, Resources

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2022PMID 36532448

Characterization of virulence and antimicrobial resistance genes ofstrain SD/21-15 from marine sediments in comparison with otherspp.

Dubey S et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-28

Clinical Trials2022PMID 35980616

Clinical and Genetic Risk Factors for Acute Incident Venous Thromboembolism in Ambulatory Patients With COVID-19.

Xie J et al. · JAMA internal medicine

Added to ASH registry: 2026-05-28

Clinical Trials2022PMID 35875569

Clonal Dissemination ofWith Binary Carriage of-Bearing Plasmids in a Chinese Hospital.

Xu Z et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2022PMID 36152028

Comparative transcriptome combined with morphophysiological analyses revealed the molecular mechanism underlyingpredation-induced antiphage defense in.

Dong Y et al. · Virulence

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35812329

Comparative Transcriptome Sequencing Analysis of Hirudo nipponia in Different Growth Periods

Ma et al. · Frontiers in physiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 36450804

Cryptic taxonomic diversity and high-latitude melanism in the glossiphoniid leech assemblage from the Eurasian Arctic

Bolotov et al. · Scientific reports

Added to ASH registry: 2026-05-28

Clinical Trials2022PMID 35626216

Detection of Unknown and Rare Pathogenic Variants in Antithrombin, Protein C and Protein S Deficiency Using High-Throughput Targeted Sequencing.

Vrtel P et al. · Diagnostics (Basel, Switzerland)

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2022PMID 36202114

Distribution and spread of the mobilised RND efflux pump gene cluster tmexCD-toprJ in clinical Gram-negative bacteria: a molecular epidemiological study.

Dong N et al. · The Lancet. Microbe

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2022PMID 35134503

Emergence of a highly colistin-resistant Aeromonas jandaei clinical isolate harbouring four genes encoding phosphoethanolamine transferases in Nepal.

Komeda T et al. · International journal of antimicrobial agents

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35776769

Erysipelothrix anatis sp. nov., Erysipelothrix aquatica sp. nov. and Erysipelothrix urinaevulpis sp. nov., three novel species of the genus, and emended description of Erysipelothrix

Eisenberg et al. · International journal of systematic and evolutionary microbiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 36289143

Establishment and characterization of a new fibroblast-like cell line from the skin of a vertebrate model, zebrafish (Danio rerio)

Sathiyanarayanan A et al. · Molecular biology reports

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2022PMID 35809723

Fate of resistome components and characteristics of microbial communities in constructed wetlands and their receiving river.

Liu L et al. · The Science of the total environment

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2022PMID 36365050

First Record of the Rare Speciesfrom Rainbow Trout (, Walbaum): Comparative Analysis with the Existing Strains.

Fernández-Bravo A et al. · Pathogens (Basel, Switzerland)

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2022PMID 36189999

Genetic Diversity, Antibiotic Resistance, and Pathogenicity ofSpecies from Food Products in Shanghai, China.

Qu FT et al. · Biomedical and environmental sciences : BES

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 36417957

Genome-wide identification and immune response analysis of serine protease inhibitor genes in the blood clam Tegillarca granosa

Wu et al. · Fish & shellfish immunology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35232253

Head transcriptome profiling of glossiphoniid leech (Helobdella austinensis) reveals clues about proboscis development

Kwak et al. · Open biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35416560

Importance of clitellar tissue in the regeneration ability of earthworm Eudrilus eugeniae.

Paul et al. · Functional & integrative genomics

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35733618

Life history strategies of Cotylurus spp. Szidat, 1928 (Trematoda, Strigeidae) in the molecular era - Evolutionary consequences and implications for taxonomy

Pyrka et al. · International journal for parasitology. Parasites and wildlife

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2022PMID 35903472

Lytic Bacteriophage PZL-Ah152 as Biocontrol Measures Against LethalWithout Distorting Gut Microbiota.

Feng C et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2022PMID 36278577

MALDI-TOF MS for Rapid Analysis of Bacterial Pathogens Causing Urinary Tract Infections in the Riyadh Region.

Anwer R et al. · Diseases (Basel, Switzerland)

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35491612

Morphological parameters of spleen and thymus of the male rats on the basis of the hirudological influence of Hirudo verbana

Aminov et al. · Annals of parasitology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2022PMID 35467407

Multidrug-Resistant Gram-Negative Bacteria and Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae from the Poultry Farm Environment.

Veloo Y et al. · Microbiology spectrum

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 36095778

On the taxonomy of the Conistra generic complex with descriptions of three new genera and a new species (Lepidoptera: Noctuidae: Noctuinae)

Benedek et al. · Zootaxa

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35488469

Postoperative consequences of cancer cachexia after head and neck free flap reconstruction

Jones et al. · Head & neck

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2022PMID 35691054

RNA-seq transcriptome analysis and identification of the theromacin antimicrobial peptide of the copepod Apocyclops royi.

Amparyup P et al. · Developmental and comparative immunology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35589020

Study on the regulatory effect of leech peptide HE-D on macrophages in atherosclerosis by transcriptome sequencing

Wang et al. · Journal of ethnopharmacology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35391381

The present state of the leech fauna (Annelida: Hirudinea) in Lithuania

Atkauskien I et al. · Zootaxa

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2022PMID 35705131

β-arrestin interacts with TRAF6 to negatively regulate the NF-κB pathway in triangle sail mussel Hyriopsis cumingii.

Jian S et al. · Fish & shellfish immunology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2022PMID 35368247

Activity-Dependent Modulation of Tonic GABA Currents by Endocannabinoids in Hirudo verbana

Paulsen RT, Burrell BD · Frontiers in synaptic neuroscience

Added to ASH registry: 2026-05-27

Genomics & Proteomics2022PMID 36142125

Coagulation Factor XIIIa and Activated Protein C Activate Platelets via GPVI and PAR1

De Simone I et al. · International journal of molecular sciences

Added to ASH registry: 2026-05-27

Genomics & Proteomics2022PMID 35694407

Comprehensive Transcriptome Sequencing Analysis of Hirudinaria manillensis in Different Growth Periods

Shan H et al. · Frontiers in physiology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2022PMID 36144584

Effects of Medicinal Leech-Related Cationic Antimicrobial Peptides on Human Blood Cells and Plasma

Vakhrusheva TV et al. · Molecules (Basel, Switzerland)

Added to ASH registry: 2026-05-27

Genomics & Proteomics2022PMID 35848975

Exploring the mechanism of hirudin in the treatment of diabetic kidney disease using network pharmacology combined with molecular docking

Xinxin P et al. · Journal of traditional Chinese medicine

Added to ASH registry: 2026-05-27

Genomics & Proteomics2022PMID 35803505

Hirudo verbana as a freshwater invertebrate model to assess the effects of polypropylene micro and nanoplastics dispersion in freshwater

Baranzini N et al. · Fish & shellfish immunology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2022PMID 36420052

MS-proteomics provides insight into the host responses towards alginate microspheres

Coron AE et al. · Materials today. Bio

Added to ASH registry: 2026-05-27

Salivary Pharmacology2022PMID 35416530

Novel contact-kinin inhibitor sylvestin targets thromboinflammation and ameliorates ischemic stroke

Zhang Z et al. · Cellular and molecular life sciences

Added to ASH registry: 2026-05-27

Genomics & Proteomics2022PMID 36283573

Phylogenetic relationships and species delimitation in Haemopis

Kvist S et al. · Molecular phylogenetics and evolution

Added to ASH registry: 2026-05-27

Genomics & Proteomics2022PMID 35510636

Serotonin mediates stress-like effects on responses to non-nociceptive stimuli in the medicinal leech Hirudo verbana

Mack D et al. · The Journal of experimental biology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2022PMID 36555595

Spatio-Temporal Changes of Extracellular Matrix (ECM) Stiffness in the Development of the Leech Hirudo verbana

Pulze L et al. · International journal of molecular sciences

Added to ASH registry: 2026-05-27

Genomics & Proteomics2022PMID 35317649

The effects of substrate porosity, mechanical substrate properties and loading conditions on the attachment performance of the Mediterranean medicinal leech (Hirudo verbana)

Kampowski T et al. · Journal of the Royal Society, Interface

Added to ASH registry: 2026-05-27

Genomics & Proteomics2022PMID 35530508

Understanding Diversity, Evolution, and Structure of Small Heat Shock Proteins in Annelida Through in Silico Analyses

de la Fuente M, Novo M · Frontiers in physiology

Added to ASH registry: 2026-05-27

Salivary Pharmacology2022PMID 35587545

Life without blood: Molecular and functional analysis of hirudins and hirudin-like factors of the Asian non-hematophagous leech Whitmania pigra

Müller C et al. · Journal of thrombosis and haemostasis : JTH

Added to ASH registry: 2026-05-26

Clinical Trials2022PMID 33884433

[Cutaneous pseudolymphoma after hirudotherapy : Case report and review]

Hanner S et al. · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete

Added to ASH registry: 2026-03-18

Clinical Trials2022PMID 32815407

Hirudotherapy in Wound Healing

Nair H et al. · The international journal of lower extremity wounds

Added to ASH registry: 2026-03-18

Salivary Pharmacology2022PMID 36006484

Make it double: identification and characterization of a Tandem-Hirudin from the Asian medicinal leech Hirudinaria manillensis

Lukas P et al. · Parasitology research

Added to ASH registry: 2026-03-18

Drug Development2022PMID 35135035

Molecular dynamic and pharmacological studies on protein-engineered hirudin variants of Hirudinaria manillensis and Hirudo medicinalis

Sun Y et al. · British journal of pharmacology

Added to ASH registry: 2026-03-18

Genomics & Proteomics2022PMID 36288175

Morganella Morganii Infection in Hirudo Medicinalis (Iran): A Case Report

Rahmati Holasoo H et al. · Veterinary sciences

Added to ASH registry: 2026-03-18

Safety & Infection Control2022PMID 34390241

Rethinking antimicrobial prophylaxis in patients receiving medicinal leech therapy

McCracken J, Koehler S, Sharma R · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

Added to ASH registry: 2026-03-18

Clinical Trials2022PMID 35510636

Serotonin mediates stress-like effects on responses to non-nociceptive stimuli in the medicinal leech Hirudo verbana

Mack D et al. · The Journal of experimental biology

Added to ASH registry: 2026-03-18

Clinical Trials2022PMID 36395588

Study on the effect of medicinal leech therapy (Hirudo medicinalis) on full-thickness excisional wound healing in the animal model

Zakian A et al. · Research in veterinary science

Added to ASH registry: 2026-03-18

Genomics & Proteomics2022PMID 37702209

The duration of rest and feeding greatly affects the re-breeding of ectoparasites: Hirudo verbana, Hirudo medicinalis and Hirudo orientalis

Aminov R, Frolov A, Aminova A · Annals of parasitology

Added to ASH registry: 2026-03-18

Genomics & Proteomics2022PMID 35073842

The genome of medicinal leech (Whitmania pigra) and comparative genomic study for exploration of bioactive ingredients

Tong L et al. · BMC genomics

Added to ASH registry: 2026-03-18

Clinical Trials2022PMID 35917641

Therapeutic effects of Hirudo medicinalis extract antigens on modulation of CD4

Al-Sayed S et al. · Veterinary parasitology

Added to ASH registry: 2026-03-18

Genomics & Proteomics2022PMID 35082098

Updates in Wound Management and Dressings

Buote N · The Veterinary clinics of North America. Small animal practice

Added to ASH registry: 2026-03-18

Genomics & Proteomics2022PMID 35187150

Validation of Medicinal Leeches (

Kvapil P et al. · Frontiers in veterinary science

Added to ASH registry: 2026-03-18

Earlier

527 articles (pre-2022)
Genomics & Proteomics2021PMID 34329918

Function of the waterfowl nests as reproduction and living areas for leeches (Annelida: Hirudinea)

Ceylan et al. · Animal reproduction science

Added to ASH registry: 2026-05-29

Clinical Trials2021PMID 34326300

A 40-Year-Old Man with Sarcoidosis and Factor V Leiden Thrombophilia Presenting with Deep Vein Thrombosis and Pulmonary Thromboembolism.

Goljan-Geremek A et al. · The American journal of case reports

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2021PMID 33930562

Characterization of a novel toll-like receptor and activation NF-κB signal pathway in triangle sail mussel Hyriopsis cumingii.

Yin S et al. · Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology

Added to ASH registry: 2026-05-28

Clinical Trials2021PMID 33691765

Coagulopathy of hospitalised COVID-19: A Pragmatic Randomised Controlled Trial of Therapeutic Anticoagulation versus Standard Care as a Rapid Response to the COVID-19 Pandemic (RAPID COVID COAG - RAPID Trial): A structured summary of a study protocol for a randomised controlled trial

Sholzberg M et al. · Trials

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 34880150

DNA Barcoding: Molecular Identification and Phylogenetic Analysis of Pheretimoid Earthworm (Metaphire sp. and Amynthas sp.) Based on Mitochondrial Partial COI Gene from Sialkot, Pakistan

Hussain M et al. · Journal of oleo science

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 33980988

Environmental DNA monitoring of oncogenic viral shedding and genomic profiling of sea turtle fibropapillomatosis reveals unusual viral dynamics

Farrell et al. · Communications biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 34175400

Gene expression changes with tumor disease and leech parasitism in the juvenile green sea turtle skin transcriptome

Kane et al. · Gene

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 35247300

Indirect effect of substances of the hemophagous parasite Hirudo verbana on the immune system of the host rats

Aminov et al. · Annals of parasitology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2021PMID 33420733

Isolation, characterization and genomic analysis of vB-AhyM-AP1, a lytic bacteriophage infecting Aeromonas hydrophila.

Pallavi B et al. · Journal of applied microbiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 34912808

It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom.

Martinez et al. · Frontiers in cell and developmental biology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2021PMID 33442859

MiRNA-seq analysis of spleen and head kidney tissue from aquacultured largemouth bass (Micropterus salmoides) in response to Aeromonas hydrophila infection.

Zhou J et al. · Functional & integrative genomics

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 33617989

Myxobdella socotrensis sp. nov., a new parasitic leech from Socotra Island, with comments on the phylogeny of Praobdellidae (Hirudinida: Arhynchobdellida)

Schenkov et al. · Parasitology international

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 33704092

Outbreak of hirudiniasis in aquarium-reared albino red-bellied pacu Piaractus brachypomus

Praveenraj et al. · Diseases of aquatic organisms

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 33674968

Placobdelloides tridens sp. n., a new species of glossiphoniid leech (Hirudinea: Rhynchobdellida) found feeding on captive Orlitia borneensis in Thailand, and an update to the host distribution of P. siamensis

Chiangkul et al. · Systematic parasitology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2021PMID 34912316

Prediction and Analysisof Genomic Islands in.

da Silva Filho AC et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-28

Salivary Pharmacology2021PMID 34599360

Short tail stories: the hirudin-like factors HLF6 and HLF7 of the Asian medicinal leech, Hirudinaria manillensis.

Müller C et al. · Parasitology research

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 33879316

Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila

Tain et al. · eLife

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2021PMID 34921862

Two NF-κB subunits are associated with antimicrobial immunity in Hyriopsis cumingii.

Zhu M et al. · Developmental and comparative immunology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 33918739

Unravelling the Extent of Diversity within the Iberian Medicinal Leeches (Hirudinea:) Using Molecules and Morphology

Arias A et al. · Biology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2021PMID 34966816

VasH Contributes to Virulence ofand Is Necessary to the T6SS-mediated Bactericidal Effect.

Li J et al. · Frontiers in veterinary science

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2021PMID 34888259

Virulence Determinants and Plasmid-Mediated Colistin ResistanceGenes in Gram-Negative Bacteria Isolated From Bovine Milk.

Tartor YH et al. · Frontiers in cellular and infection microbiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 34556619

Virulent and Multiple Antimicrobial Resistance Aeromonas hydrophila Isolated from Diseased Nile Tilapia Fish (Oreochromis niloticus) in Egypt with Sequencing of Some Virulence-Associated Genes

Saleh et al. · Biocontrol science

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 34944561

WPK5, a Novel Kunitz-Type Peptide from the LeechInhibiting Factor XIa, and Its Loop-Replaced Mutant to Improve Potency.

Zheng YZ et al. · Biomedicines

Added to ASH registry: 2026-05-28

Genomics & Proteomics2021PMID 34944133

A Systematic Review of Complementary and Alternative Veterinary Medicine: "Miscellaneous Therapies"

Bergh A et al. · Animals : an open access journal from MDPI

Added to ASH registry: 2026-05-27

Genomics & Proteomics2021PMID 34681071

Amazing Discoveries of Benthic Fauna from the Abyssal Zone of Lake Baikal

Kondratov IG et al. · Biology (Basel)

Added to ASH registry: 2026-05-27

Genomics & Proteomics2021PMID 34725716

Comparison of body wall histologic structure of two medicinal leeches Hirudo sulukii and Hirudo verbana (Hirudinida: Hirudinidae)

Gul MU, Cakici O · Cell and tissue research

Added to ASH registry: 2026-05-27

Genomics & Proteomics2021PMID 34616211

DNA barcoding for species delimitation of the freshwater leech genus from the Western Balkan (Hirudinea, Glossiphoniidae)

Jovanovic M et al. · Biodiversity Data Journal

Added to ASH registry: 2026-05-27

Genomics & Proteomics2021PMID 34616211

DNA barcoding for species delimitation of the freshwater leech genus Glossiphonia from the Western Balkan

Jovanović M et al. · Biodiversity data journal

Added to ASH registry: 2026-05-27

Genomics & Proteomics2021PMID 34951168

Effect of heavy metal lead on anticoagulant activity of leech based on label-free quantitative proteomics

Xue M et al. · Zhongguo Zhong yao za zhi

Added to ASH registry: 2026-05-27

Drug Development2021PMID 34824278

Efficacy and safety of next-generation tick transcriptome-derived direct thrombin inhibitors

Koh CY et al. · Nature Communications

Added to ASH registry: 2026-05-27

Drug Development2021PMID 34481024

Engineering a 'three-in-one' hirudin prodrug to reduce bleeding risk: A proof-of-concept study

Zhu Y et al. · Journal of Controlled Release

Added to ASH registry: 2026-05-27

Safety & Infection Control2021PMID 33674439

Old World Leech Gut Microbial Community Structure Conserved in a New World Leech

McClure EA et al. · Applied and environmental microbiology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2021PMID 33674439

Old World Leech Gut Microbial Community Structure Conserved in a New World Leech (Macrobdella)

McClure EA et al. · Applied and Environmental Microbiology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2021PMID 34893255

Structure and cleavage pattern of a hyaluronate 3-glycanohydrolase in the glycoside hydrolase 79 family

Huang H et al. · Carbohydrate Polymers

Added to ASH registry: 2026-05-27

Genomics & Proteomics2021PMID 33527140

The origin and evolution of antistasin-like proteins in leeches

Iwama RE et al. · Genome biology and evolution

Added to ASH registry: 2026-05-27

Drug Development2021PMID 34688099

Thrombolytic and anticoagulant effects of a recombinant staphylokinase-hirudin fusion protein

Ren K et al. · Thrombosis Research

Added to ASH registry: 2026-05-27

Safety & Infection Control2021PMID 34252261

Hirudotherapy (medicinal leeches) for treatment of upper airway obstruction in a dog

Trenholme H, Masseau I, Reinero C · Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

Added to ASH registry: 2026-03-18

Genomics & Proteomics2021PMID 33171014

Leech blood-meal invertebrate-derived DNA reveals differences in Bornean mammal diversity across habitats

Drinkwater R et al. · Molecular ecology

Added to ASH registry: 2026-03-18

Genomics & Proteomics2021PMID 34315461

Leech therapy (Hirudo medicinalis) attenuates testicular damages induced by testicular ischemia/reperfusion in an animal model

Davoodi F et al. · BMC veterinary research

Added to ASH registry: 2026-03-18

Salivary Pharmacology2021PMID 34889897

Recombinant Destabilase from

Bobrovsky P et al. · Current issues in molecular biology

Added to ASH registry: 2026-03-18

Genomics & Proteomics2021PMID 34477962

Spectral responses across a dorsal-ventral array of dermal sensilla in the medicinal leech

Groves T, Jellies J · Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology

Added to ASH registry: 2026-03-18

Genomics & Proteomics2021PMID 34331853

The influence of the planting time and conditions on the reproductive properties of Hirudo verbana and Hirudo medicinalis

Aminov R, Frolov A, Aminova A · Annals of parasitology

Added to ASH registry: 2026-03-18

Clinical Trials2021PMID 32779247

The Vascularity of Ayurvedic Leech Therapy: Sensory Translations and Emergent Agencies in Interspecies Medicine

Brooks L · Medical anthropology quarterly

Added to ASH registry: 2026-03-18

Salivary Pharmacology2020PMID 32508488

A new species of buffalo leech in the genusWhitman, 1886 (Arhynchobdellida, Hirudinidae) from Thailand.

Jeratthitikul E et al. · ZooKeys

Added to ASH registry: 2026-05-28

Genomics & Proteomics2020PMID 32974004

Autophagy and its role in regeneration and remodeling within invertebrate

Song Q et al. · Cell & bioscience

Added to ASH registry: 2026-05-28

Genomics & Proteomics2020PMID 32507268

Effects of maternal age on reproductive performance of the southern medicinal leech, Hirudo verbana Carena, 1820

Ceylan · Animal reproduction science

Added to ASH registry: 2026-05-28

Genomics & Proteomics2020PMID 33199759

First freshwater mussel-associated piscicolid leech from East Asia

Bolotov et al. · Scientific reports

Added to ASH registry: 2026-05-28

Clinical Trials2020PMID 32731838

Genetic risk factors for venous thromboembolism.

Zöller B et al. · Expert review of hematology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2020PMID 33458148

Mitogenome of the blood feeding leech(Hirudinida: Glossiphoniidae) from Tabasco, Mexico

Sosa-Jiménez VM et al. · Mitochondrial DNA. Part B, Resources

Added to ASH registry: 2026-05-28

Genomics & Proteomics2020PMID 32043208

Recombinant HvRNASET2 protein induces marked connective tissue remodelling in the invertebrate model Hirudo verbana

Baranzini et al. · Cell and tissue research

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2020PMID 33274900

Use of Bacteriophage to Control ExperimentalInfection in Tilapia ().

Phumkhachorn P et al. · Pakistan journal of biological sciences : PJBS

Added to ASH registry: 2026-05-28

Genomics & Proteomics2020PMID 33114362

Whole-Genome Sequence ofCVM861 Isolated from Diarrhetic Neonatal Swine.

Poole TL et al. · Microorganisms

Added to ASH registry: 2026-05-28

Salivary Pharmacology2020PMID 33352806

3D Reconstruction of HvRNASET2 Molecule to Understand Its Antibacterial Role

Baranzini N et al. · International journal of molecular sciences

Added to ASH registry: 2026-05-27

Genomics & Proteomics2020PMID 32119950

A peptide inhibitor of macrophage migration in atherosclerosis purified from the leech Whitmania pigra

Hu B et al. · Journal of ethnopharmacology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2020PMID 32205202

Characterization of a monoacylglycerol lipase in the medicinal leech, Hirudo verbana

Kabeiseman E et al. · Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2020PMID 32698877

Correction to: Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches

Babenko VV et al. · BMC genomics

Added to ASH registry: 2026-05-27

Genomics & Proteomics2020PMID 32010187

Draft Genome of the Asian Buffalo Leech

Guan DL et al. · Front Genet

Added to ASH registry: 2026-05-27

Genomics & Proteomics2020PMID 32349672

Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches

Babenko VV et al. · BMC genomics

Added to ASH registry: 2026-05-27

Genomics & Proteomics2020PMID 32349672

Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches

Babenko VV et al. · BMC Genomics

Added to ASH registry: 2026-05-27

Drug Development2020PMID 32561727

Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum

Wang Y et al. · Nature Communications

Added to ASH registry: 2026-05-27

Salivary Pharmacology2020PMID 32349294

European Medicinal Leeches - New Roles in Modern Medicine

Lemke S et al. · Biomedicines

Added to ASH registry: 2026-05-27

Genomics & Proteomics2020PMID 32673516

Exploring the attachment of the Mediterranean medicinal leech to porous substrates

Kampowski T et al. · Journal of the Royal Society, Interface

Added to ASH registry: 2026-05-27

Genomics & Proteomics2020PMID 32848363

Hirudin protects against kidney damage in streptozotocin-induced diabetic nephropathy rats by inhibiting inflammation via P38 MAPK/NF-κB pathway

Han J et al. · Drug design, development and therapy

Added to ASH registry: 2026-05-27

Genomics & Proteomics2020PMID 32417374

Hirudin reduces nephropathy microangiopathy in STZ-induced diabetes rats by inhibiting endothelial cell migration

Pang X et al. · Life sciences

Added to ASH registry: 2026-05-27

Genomics & Proteomics2020PMID 32736137

Proteome and phosphoproteome profiling reveals the regulation mechanism of hibernation in a freshwater leech (Whitmania pigra)

Shi H et al. · Journal of proteomics

Added to ASH registry: 2026-05-27

Drug Development2020PMID 31949293

RGD-hirudin-based low molecular weight peptide prevents blood coagulation via subcutaneous injection

Li YR et al. · Acta Pharmacologica Sinica

Added to ASH registry: 2026-05-27

Genomics & Proteomics2020PMID 32371144

Serum metabolomic profiles reveal the impact of BuZangTongLuo formula on metabolic pathways in diabetic mice with hindlimb ischemia

Zheng J et al. · Journal of ethnopharmacology

Added to ASH registry: 2026-05-27

Drug Development2020PMID 32910358

Temperature-controlled molecular weight of hyaluronic acid produced by engineered Bacillus subtilis

Li Y et al. · Biotechnology Letters

Added to ASH registry: 2026-05-27

Antimicrobial Resistance2020PMID 32992666

The Hirudo medicinalis microbiome is a source of new antimicrobial peptides

Grafskaia E et al. · International journal of molecular sciences

Added to ASH registry: 2026-05-27

Salivary Pharmacology2020PMID 32634521

The molecular characterization, expression analysis and antimicrobial activity of theromacin from Asian polychaeta (Perinereis linea)

Joo MS et al. · Developmental and comparative immunology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2020PMID 32349672

Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches

Babenko VV, Podgorny OV, Manuvera VA et al. · BMC genomics

Added to ASH registry: 2026-05-26

Genomics & Proteomics2020PMID 32210967

Antimicrobial Role of RNASET2 Protein During Innate Immune Response in the Medicinal Leech

Baranzini N et al. · Frontiers in immunology

Added to ASH registry: 2026-03-18

Drug Development2020PMID 33188246

Cell-free synthesis of the hirudin variant 1 of the blood-sucking leech Hirudo medicinalis

Wüstenhagen D et al. · Scientific reports

Added to ASH registry: 2026-03-18

Genomics & Proteomics2020PMID 32555498

Draft genome of the European medicinal leech Hirudo medicinalis (Annelida, Clitellata, Hirudiniformes) with emphasis on anticoagulants

Kvist S et al. · Scientific reports

Added to ASH registry: 2026-03-18

Drug Development2020PMID 31733150

Hirudin or hirudin-like factor - that is the question: insights from the analyses of natural and synthetic HLF variants

Müller C et al. · FEBS letters

Added to ASH registry: 2026-03-18

Clinical Trials2020PMID 30709686

Medical leech therapy in Ayurveda and biomedicine - A review

Singh S, Rajoria K · Journal of Ayurveda and integrative medicine

Added to ASH registry: 2026-03-18

Drug Development2020PMID 32363441

The hirudin-like factors HLF3 and HLF4-hidden hirudins of European medicinal leeches

Müller C et al. · Parasitology research

Added to ASH registry: 2026-03-18

Genomics & Proteomics2019PMID 30681200

Analysis of synonymous codon usage pattern of genes in unique non-blood-sucking leech Whitmania pigra

Khan et al. · Journal of cellular biochemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics2019PMID 31726983

Comparative transcriptomics in Syllidae (Annelida) indicates that posterior regeneration and regular growth are comparable, while anterior regeneration is a distinct process.

Ribeiro et al. · BMC genomics

Added to ASH registry: 2026-05-28

Drug Development2019PMID 31205020

Crystal structures of the recombinant β-factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics.

Pathak M et al. · Acta crystallographica. Section D, Structural biology

Added to ASH registry: 2026-05-28

Clinical Trials2019PMID 31577252

Hereditary thrombophilia.

Dautaj A et al. · Acta bio-medica : Atenei Parmensis

Added to ASH registry: 2026-05-28

Clinical Trials2019PMID 31387441

Impact of Baseline Anemia in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention: A Prespecified Analysis From the VALIDATE-SWEDEHEART Trial.

Wester A et al. · Journal of the American Heart Association

Added to ASH registry: 2026-05-28

Genomics & Proteomics2019PMID 31103350

Investigation of reproductive efficiency, growth performance and survival of the southern medicinal leech, Hirudo verbana Carena, 1820 fed with mammalian and poultry blood

Manav et al. · Animal reproduction science

Added to ASH registry: 2026-05-28

Clinical Trials2019PMID 30703819

Laboratory Diagnostics in Thrombophilia.

Linnemann B et al. · Hamostaseologie

Added to ASH registry: 2026-05-28

Genomics & Proteomics2019PMID 30393850

On the origin of leeches by evolution of development

Kuo et al. · Development, growth & differentiation

Added to ASH registry: 2026-05-28

Drug Development2019PMID 30985986

An assay to measure levels of factor Xa inhibitors in blood and plasma

Kim PY et al. · Journal of Thrombosis and Haemostasis

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 30997489

An efficient and robust laboratory workflow and tetrapod database for larger scale environmental DNA studies

Axtner J et al. · GigaScience

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 30806729

Bacterial Community of the Digestive Tract of the European Medicinal Leech (Hirudo verbana) from the Danube River

Neupane S et al. · Microbial Ecology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31716590

Broad geographic sampling and DNA barcoding do not support the presence of Helobdella stagnalis in North America

Iwama RE et al. · Zootaxa

Added to ASH registry: 2026-05-27

Drug Development2019PMID 31222999

Construction of engineered Streptococcus zooepidemicus for the production of hyaluronic acid ligosaccharide

Wei C et al. · Sheng Wu Gong Cheng Xue Bao (Chinese Journal of Biotechnology)

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 30644063

DNA barcoding reveals association of Glossiphoniidae species on endangered freshwater turtles in Northeast India

Kundu S et al. · Acta parasitologica

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 32237346

Effect of lead pollution on anticoagulant effect of Whitmania pigra based on in vitro anticoagulation experiment

Luo XM et al. · Zhongguo Zhong yao za zhi

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31602878

Effects of 17-E2 on growth and gonad development of overwintering Whitmania pigra

Wang S et al. · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31262786

Electrophysiology and transcriptomics reveal two photoreceptor classes and complex visual integration in

Stowasser A et al. · J Exp Biol

Added to ASH registry: 2026-05-27

Salivary Pharmacology2019PMID 30794960

Gene cloning and expression of a partial sequence of Hirudomacin, an antimicrobial protein that is increased in leech (Hirudo nipponica Whitman) after a blood meal

Ding A et al. · Comparative biochemistry and physiology. Part B

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31747540

Genetic variation, pseudocryptic diversity, and phylogeny of Erpobdella (Annelida: Hirudinida: Erpobdelliformes), with emphasis on Canadian species

Anderson K et al. · Molecular Phylogenetics and Evolution

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31163003

Hirudin and decorsins of the North American medicinal leech: gene structure reveals homology to hirudins and hirudin-like factors of Eurasian medicinal leeches

Muller C et al. · The Journal of parasitology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31592161

Identification and characterization of hirudin-HN, a new thrombin inhibitor, from the salivary glands of Hirudo nipponia

Cheng B et al. · PeerJ

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 30880165

In-depth profiles of bioactive large molecules in saliva secretions of leeches determined by combining salivary gland proteome and transcriptome data

Liu Z et al. · Journal of proteomics

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31865657

Internal and External Morphological Characteristics of the Medicinal Leech Species Hirudo sulukii and Hirudo verbana

Saglam N · Turkiye parazitolojii dergisi

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31877385

Loss of ELK1 has differential effects on age-dependent organ fibrosis

Cairns JT et al. · The international journal of biochemistry & cell biology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 30622136

Nonconventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP

Chepurny OG et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-27

Drug Development2019PMID 30802064

Novel Strategy of Gene Delivery System Based on Dendrimer Loaded Recombinant Hirudine Plasmid for Thrombus Targeting Therapy

Chen J et al. · Molecular pharmaceutics

Added to ASH registry: 2026-05-27

Drug Development2019PMID 30802064

Novel Strategy of Gene Delivery System Based on Dendrimer Loaded Recombinant Hirudine Plasmid for Thrombus Targeting Therapy

Chen J et al. · Molecular Pharmaceutics

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31414949

Phylogenetic position and description of a new species of medicinal leech from the eastern United States

Phillips AJ et al. · The Journal of parasitology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31271070

Prey, populations, and the pleistocene: evidence for low COI variation in a widespread North American leech

Mack J et al. · Mitochondrial DNA Part A

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31011131

Purification and characterization of a novel anti-coagulant from the leech Hirudinaria manillensis

Cheng RM et al. · Zool Res

Added to ASH registry: 2026-05-27

Drug Development2019PMID 31005062

The Direct Thrombin Inhibitors Dabigatran and Lepirudin Inhibit GPIbalpha-Mediated Platelet Aggregation

Trabold K et al. · Thrombosis and Haemostasis

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31148528

The salivary transcriptome of Limnatis nilotica and orthology determination of major leech anticoagulants

Iwama R et al. · Parasitology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2019PMID 31031937

Transcriptomics and differential gene expression in Helobdella: contrasting feeding and fasting modes

Khan MS · Ecology and evolution

Added to ASH registry: 2026-05-27

Salivary Pharmacology2019PMID 31472896

A novel protease-activated receptor 1 inhibitor from the leech Whitmania pigra

Ren SH, Liu ZJ, Cao Y et al. · Chinese journal of natural medicines

Added to ASH registry: 2026-05-26

Safety & Infection Control2019PMID 30806729

Bacterial Community of the Digestive Tract of the European Medicinal Leech (Hirudo verbana) from the Danube River

Neupane S et al. · Microbial ecology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2019PMID 30880165

In-depth profiles of bioactive large molecules in saliva secretions of leeches determined by combining salivary gland proteome and transcriptome data

Liu Z, Tong X, Su Y et al. · Journal of proteomics

Added to ASH registry: 2026-05-26

Genomics & Proteomics2019PMID 30368505

AIF-1 and RNASET2 Play Complementary Roles in the Innate Immune Response of Medicinal Leech

Baranzini N et al. · Journal of innate immunity

Added to ASH registry: 2026-03-18

Clinical Trials2019PMID 31841493

HIRUDOTHERAPY IN PRESBYACUZIS PRAECOX IN CLEAN-UP WORKERS AFTER THE CHORNOBYL ACCIDENT DURING THE POST-CATASTROPHE YEARS

Zabolotnyi D, Mishchanchuk N · Problemy radiatsiinoi medytsyny ta radiobiolohii

Added to ASH registry: 2026-03-18

Genomics & Proteomics2019PMID 31865657

Internal and External Morphological Characteristics of the Medicinal Leech Species

Sağlam N · Turkiye parazitolojii dergisi

Added to ASH registry: 2026-03-18

Genomics & Proteomics2019PMID 31302447

Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens

Grafskaia E et al. · European journal of medicinal chemistry

Added to ASH registry: 2026-03-18

Drug Development2019PMID 31170978

The effects of a hirudin/liposome complex on a diabetic nephropathy rat model

Wang H et al. · BMC complementary and alternative medicine

Added to ASH registry: 2026-03-18

Genomics & Proteomics2018PMID 30028871

An annotated CNS transcriptome of the medicinal leech, Hirudo verbana: De novo sequencing to characterize genes associated with nervous system activity

Northcutt AJ et al. · PloS one

Added to ASH registry: 2026-05-28

Genomics & Proteomics2018PMID 29337984

Anteroposterior axis patterning by early canonical Wnt signaling during hemichordate development.

Darras et al. · PLoS biology

Added to ASH registry: 2026-05-28

Salivary Pharmacology2018PMID 30239061

Antiplatelet and anticoagulant activities of two phospholipase A2s purified from Cerastes cerastes venom: Structure-function relationship.

Fatah C et al. · Journal of biochemical and molecular toxicology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2018PMID 29689349

Comparative transcriptomic analysis reveals the mechanism of leech environmental adaptation

Liu et al. · Gene

Added to ASH registry: 2026-05-28

Genomics & Proteomics2018PMID 30239540

De novo assembly and comparative transcriptome characterization of Poecilobdella javanica provide insight into blood feeding of medicinal leeches

Liu et al. · Molecular omics

Added to ASH registry: 2026-05-28

Genomics & Proteomics2018PMID 29396890

Duplicated FoxA genes in the leech Helobdella: Insights into the evolution of direct development in clitellate annelids.

Kuo et al. · Developmental dynamics : an official publication of the American Association of Anatomists

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2018PMID 30529463

Molecular cloning and functional characterization of a short peptidoglycan recognition protein from triangle-shell pearl mussel (Hyriopsis cumingii).

Huang Y et al. · Fish & shellfish immunology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2018PMID 30141118

New Antarctic deep-sea weird leech (Hirudinida: Piscicolidae): morphological features and phylogenetic relationships

Utevsky et al. · Systematic parasitology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2018PMID 30115014

PdumBase: a transcriptome database and research tool for Platynereis dumerilii and early development of other metazoans.

Chou et al. · BMC genomics

Added to ASH registry: 2026-05-28

Clinical Trials2018PMID 30547428

Pediatric Thrombotic Events: Incidence, Clinical Risk Factors and Outcome.

Gupta T et al. · Indian journal of pediatrics

Added to ASH registry: 2026-05-28

Genomics & Proteomics2018PMID 29351062

Phylogeny and cocoon production in the parasitic leech Myzobdella lugubris Leidy, 1851 (Hirudinidae, Piscicolidae)

Saglam et al. · Acta parasitologica

Added to ASH registry: 2026-05-28

Clinical Trials2018PMID 29727017

Recent advances in the discovery and development of factor XI/XIa inhibitors.

Al-Horani RA et al. · Medicinal research reviews

Added to ASH registry: 2026-05-28

Genomics & Proteomics2018PMID 29716181

The impact of fetal load of Hirudo verbana saline extract antigens on morphometrical, hematological and immunological parameters of rats in the early stages of post-embryonic development

Aminov et al. · Annals of parasitology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2018PMID 29778721

Worms that suck: Phylogenetic analysis of Hirudinea solidifies the position of Acanthobdellida and necessitates the dissolution of Rhynchobdellida

Tessler et al. · Molecular phylogenetics and evolution

Added to ASH registry: 2026-05-28

Genomics & Proteomics2018PMID 30016953

Analysis of codon usage patterns in Hirudinaria manillensis reveals a preference for GC-ending codons caused by dominant selection constraints

Guan DL et al. · BMC genomics

Added to ASH registry: 2026-05-27

Salivary Pharmacology2018PMID 30384521

Cloning of Guamerin gene in Whitmania pigra and its spatio-temporal expression analysis after ingestion

Wu MJ et al. · Zhongguo Zhong yao za zhi

Added to ASH registry: 2026-05-27

Salivary Pharmacology2018PMID 29676090

Effect of ingestion on antithrombin activity in different tissues of Whitmania pigra

Wu MJ et al. · China journal of Chinese materia medica

Added to ASH registry: 2026-05-27

Genomics & Proteomics2018PMID 30384524

Effects of Cu enrichment and release on growth internal quality and relative gene expression of Whitmania pigra

Shi GW et al. · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Added to ASH registry: 2026-05-27

Genomics & Proteomics2018PMID 30373118

Isolation and characterization of poecistasin, an anti-thrombotic antistasin-type serine protease inhibitor from leech

Tang X et al. · Toxins

Added to ASH registry: 2026-05-27

Genomics & Proteomics2018PMID 30260966

Large scale changes in the transcriptome of Eisenia fetida during regeneration

Bhambri A et al. · PloS one

Added to ASH registry: 2026-05-27

Genomics & Proteomics2018PMID 29505345

Marine leech anticoagulant diversity and evolution

Tessler M et al. · The Journal of parasitology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2018PMID 30339694

Transcriptomic analysis of the salivary gland of medicinal leech Hirudo nipponia

Lu Z, Shi P, You H, Liu Y, Chen S · PLoS one

Added to ASH registry: 2026-05-26

Safety & Infection Control2018PMID 30042201

Low-Level Antimicrobials in the Medicinal Leech Select for Resistant Pathogens That Spread to Patients

Beka L et al. · mBio

Added to ASH registry: 2026-03-18

Genomics & Proteomics2018PMID 30572617

Medicinal Leech CNS as a Model for Exosome Studies in the Crosstalk between Microglia and Neurons

Raffo-Romero A et al. · International journal of molecular sciences

Added to ASH registry: 2026-03-18

Salivary Pharmacology2018PMID 29559913

Novel Sodium Channel Inhibitor From Leeches

Wang G et al. · Frontiers in pharmacology

Added to ASH registry: 2026-03-18

Drug Development2018PMID 30339694

Transcriptomic analysis of the salivary gland of medicinal leech Hirudo nipponia

Lu Z et al. · PloS one

Added to ASH registry: 2026-03-18

Safety & Infection Control2017PMID 28650000

Andexanet alfa: a recombinant mimetic of human factor Xa for the reversal of anticoagulant therapies.

Escolar G et al. · Drugs of today (Barcelona, Spain : 1998)

Added to ASH registry: 2026-05-28

Genomics & Proteomics2017PMID 28827736

Cellular responses induced by multi-walled carbon nanotubes: in vivo and in vitro studies on the medicinal leech macrophages

Girardello et al. · Scientific reports

Added to ASH registry: 2026-05-28

Genomics & Proteomics2017PMID 28196471

Characterization and expression profiling of serine protease inhibitors in the diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae)

Lin et al. · BMC genomics

Added to ASH registry: 2026-05-28

Genomics & Proteomics2017PMID 33473780

Complete mithochondrial genome of(Hirudinida: Arhychobdellida: Ozobranchidae)

Liu X et al. · Mitochondrial DNA. Part B, Resources

Added to ASH registry: 2026-05-28

Genomics & Proteomics2017PMID 29277454

Entrapped by the uneven central and Middle Eastern terrains: Genetic status of populations of Hirudo orientalis (Annelida, Clitellata, Hirudinida) with a phylogenetic review of the genus Hirudo

Darabi-Darestani K et al. · Molecular phylogenetics and evolution

Added to ASH registry: 2026-05-28

Genomics & Proteomics2017PMID 28856584

H,N andC resonance assignments of Ixolaris, a tissue factor pathway inhibitor from the tick salivary gland.

De Paula VS et al. · Biomolecular NMR assignments

Added to ASH registry: 2026-05-28

Genomics & Proteomics2017PMID 28777090

High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti

Torquato et al. · Acta crystallographica. Section F, Structural biology communications

Added to ASH registry: 2026-05-28

Genomics & Proteomics2017PMID 28343561

Locomotor and energetic consequences of behavioral thermoregulation in the sanguivorous leech Hirudo verbana

Hitchcock et al. · Journal of thermal biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2017PMID 28437179

Mechanically Oriented 3D Collagen Hydrogel for Directing Neurite Growth.

Antman-Passig M et al. · Tissue engineering. Part A

Added to ASH registry: 2026-05-28

Genomics & Proteomics2017PMID 28666786

Phylogenetic analysis of Placobdella (Hirudinea: Rhynchobdellida: Glossiphoniidae) with consideration of COI variation

de Carle D et al. · Molecular phylogenetics and evolution

Added to ASH registry: 2026-05-28

Clinical Trials2017PMID 29074563

Pregnancy, thrombophilia, and the risk of a first venous thrombosis: systematic review and bayesian meta-analysis.

Croles FN et al. · BMJ (Clinical research ed.)

Added to ASH registry: 2026-05-28

Genomics & Proteomics2017PMID 28699036

Spatiotemporal expression of a twist homolog in the leech Helobdella austinensis.

Kim et al. · Development genes and evolution

Added to ASH registry: 2026-05-28

Genomics & Proteomics2017PMID 28692290

Top-Down Atmospheric Ionization Mass Spectrometry Microscopy Combined With Proteogenomics

Hsu CC et al. · Analytical chemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics2017PMID 29242432

Contribution to the morphological description of the marine leech Ozobranchus margoi by using combined histology, micro-CT and SEM

Cascarano MC et al. · Zootaxa

Added to ASH registry: 2026-05-27

Genomics & Proteomics2017PMID 28290215

Genetic assessment of leech species from yak (Bos grunniens) in the tract of Northeast India

Chatterjee N et al. · Mitochondrial DNA Part A

Added to ASH registry: 2026-05-27

Genomics & Proteomics2017PMID 28290215

Genetic assessment of leech species from yak in the tract of Northeast India

Chatterjee N et al. · Mitochondrial DNA Part A

Added to ASH registry: 2026-05-27

Genomics & Proteomics2017PMID 29051571

A new cellular type in invertebrates: first evidence of telocytes in leech Hirudo medicinalis

Pulze L et al. · Scientific reports

Added to ASH registry: 2026-03-18

Drug Development2017PMID 27483399

In-vitro antileishmanial potential of peptide drug hirudin

Khan H et al. · Chemical biology & drug design

Added to ASH registry: 2026-03-18

Salivary Pharmacology2016PMID 26748875

Allosterism-based simultaneous, dual anticoagulant and antiplatelet action: allosteric inhibitor targeting the glycoprotein Ibα-binding and heparin-binding site of thrombin.

Mehta AY et al. · Journal of thrombosis and haemostasis : JTH

Added to ASH registry: 2026-05-28

Salivary Pharmacology2016PMID 27176910

Comparative Mitogenomics of Leeches (Annelida: Clitellata): Genome Conservation and Placobdella-Specific trnD Gene Duplication.

Oceguera-Figueroa A et al. · PloS one

Added to ASH registry: 2026-05-28

Clinical Trials2016PMID 27183984

G-Quadruplex Aptamers to Human Thrombin Versus Other Direct Thrombin Inhibitors: The Focus on Mechanism of Action and Drug Efficiency as Anticoagulants.

Zavyalova E et al. · Current medicinal chemistry

Added to ASH registry: 2026-05-28

Clinical Trials2016PMID 26960279

Management Overview: Taking a Patient with Intracranial Hemorrhage Related to Direct Oral Anticoagulants to the Operating Room.

Alturki A et al. · World neurosurgery

Added to ASH registry: 2026-05-28

Clinical Trials2016PMID 27986523

Outcome of Patients with Venous Thromboembolism and Factor V Leiden or Prothrombin 20210 Carrier Mutations During the Course of Anticoagulation.

Tzoran I et al. · The American journal of medicine

Added to ASH registry: 2026-05-28

Clinical Trials2016PMID 27797404

Pentasaccharides for the prevention of venous thromboembolism

Dong K et al. · The Cochrane database of systematic reviews

Added to ASH registry: 2026-05-28

Drug Development2016PMID 27904902

A novel hirudin derivative inhibiting thrombin without bleeding for subcutaneous injection

Zhao B et al. · Thrombosis and Haemostasis

Added to ASH registry: 2026-05-27

Genomics & Proteomics2016PMID 27021679

A novel selective inhibitor to thrombin-induced platelet aggregation purified from the leech Whitmania pigra

Liu X et al. · Biochem Biophys Res Commun

Added to ASH registry: 2026-05-27

Safety & Infection Control2016PMID 26896136

A Tale of Transmission: Aeromonas veronii Activity within Leech-Exuded Mucus

Ott BM et al. · Applied and environmental microbiology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2016PMID 27103675

Be ready at any time: postprandial synthesis of salivary proteins in salivary gland cells of the haematophagous leech Hirudo verbana

Lemke S et al. · The Journal of experimental biology

Added to ASH registry: 2026-05-27

Drug Development2016PMID 26751617

Combinatorial Evolution of Enzymes and Synthetic Pathways Using One-Step PCR

Jin P et al. · ACS Synthetic Biology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2016PMID 26743128

Genetic variation in Whitmania pigra, Hirudo nipponica and Poecilobdella manillensis, three endemic and endangered species in China using SSR and TRAP markers

Liu F et al. · Gene

Added to ASH registry: 2026-05-27

Salivary Pharmacology2016PMID 27667513

Identification and characterization of a novel neuropeptide (neuropeptide Y-HS) from leech salivary gland of Haemadipsa sylvestris

Liu WH et al. · Chinese journal of natural medicines

Added to ASH registry: 2026-05-27

Genomics & Proteomics2016PMID 27487778

Identification and characterization of novel anticoagulant peptide with thrombolytic effect and nutrient oligopeptides from Whitmania pigra

Ren Y et al. · Amino acids

Added to ASH registry: 2026-05-27

Genomics & Proteomics2016PMID 28895330

In vitro anticoagulant activity of different processed products of Whitmania pigra by water extraction and bionic extraction

Shan Y et al. · Zhongguo Zhong yao za zhi

Added to ASH registry: 2026-05-27

Antimicrobial Resistance2016PMID 27381717

Neuro-immune lessons from an annelid: The medicinal leech

Tasiemski A, Salzet M · Developmental and comparative immunology

Added to ASH registry: 2026-05-27

Drug Development2016PMID 26851304

Production of specific-molecular-weight hyaluronan by metabolically engineered Bacillus subtilis 168

Jin P et al. · Metabolic Engineering

Added to ASH registry: 2026-05-27

Genomics & Proteomics2016PMID 27129037

Mechanics of cocoon secretion in a segmented worm (Annelida: Hirudinidae)

Rossi AM et al. · Micron (Oxford, England : 1993)

Added to ASH registry: 2026-05-26

Genomics & Proteomics2016PMID 33473467

Draft mitochondrial genomes of

Nikitina A et al. · Mitochondrial DNA. Part B, Resources

Added to ASH registry: 2026-03-18

Genomics & Proteomics2015PMID 25657285

Complete Genome Sequence of the Novel Leech Symbiont Mucinivorans hirudinis M3T

Nelson et al. · Genome announcements

Added to ASH registry: 2026-05-29

Genomics & Proteomics2015PMID 26679583

Draft Genome Sequence of Pedobacter sp. Strain Hv1, an Isolate from Medicinal Leech Mucosal Castings

Ott et al. · Genome announcements

Added to ASH registry: 2026-05-29

Genomics & Proteomics2015PMID 25911035

Basic morphofunctional features of pharmaceutic leech (Hirudo verbana Carena, 1820) tissues in various forms of response after hirudotherapeutic procedures

Frolov et al. · Annals of parasitology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2015PMID 25787951

Compensatory plasticity restores locomotion after chronic removal of descending projections.

Harley CM et al. · Journal of neurophysiology

Added to ASH registry: 2026-05-28

Salivary Pharmacology2015PMID 25957161

Conserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions.

Kim TK et al. · International journal for parasitology

Added to ASH registry: 2026-05-28

Clinical Trials2015PMID 25592075

Factor V Leiden mutation and high FVIII are associated with an increased risk of VTE in women with breast cancer during adjuvant tamoxifen - results from a prospective, single center, case control study.

Kovac M et al. · European journal of internal medicine

Added to ASH registry: 2026-05-28

Genomics & Proteomics2015PMID 25880897

Hm-MyD88 and Hm-SARM: two key regulators of the neuroimmune system and neural repair in the medicinal leech.

Rodet F et al. · Scientific reports

Added to ASH registry: 2026-05-28

Genomics & Proteomics2015PMID 25766395

On exploration of geometrically constrained space by medicinal leeches Hirudo verbana

Adamatzky · Bio Systems

Added to ASH registry: 2026-05-28

Genomics & Proteomics2015PMID 25709207

Peptides from two sanguinovorous leeches analyzed by ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometric detector

Xiao et al. · Pharmacognosy magazine

Added to ASH registry: 2026-05-28

Genomics & Proteomics2015PMID 26454017

Solving a Bloody Mess: B-Vitamin Independent Metabolic Convergence among Gammaproteobacterial Obligate Endosymbionts from Blood-Feeding Arthropods and the Leech Haementeria officinalis

Manzano-Marín A et al. · Genome biology and evolution

Added to ASH registry: 2026-05-28

Drug Development2015PMID 26400022

A novel stearic acid-modified hirudin peptidomimetic with improved pharmacokinetic properties and anticoagulant activity

Liu Z et al. · Scientific Reports

Added to ASH registry: 2026-05-27

Genomics & Proteomics2015PMID 26116877

Building exploration with leeches Hirudo verbana

Adamatzky A, Sirakoulis GC · Bio Systems

Added to ASH registry: 2026-05-27

Genomics & Proteomics2015PMID 25620963

Characterization of shed medicinal leech mucus reveals a diverse microbiota

Ott BM et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2015PMID 26535976

Comparative transcriptomic analyses of three species of Placobdella confirms a single origin of blood feeding in leeches

Siddall ME et al. · The Journal of parasitology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2015PMID 25977819

De novo transcriptome assembly databases for the central nervous system of the medicinal leech

Northcutt AJ et al. · Scientific data

Added to ASH registry: 2026-05-27

Genomics & Proteomics2015PMID 25585615

Improving the bioactivity of rHirudin with boronophenylalanine site-specific modification

Xin X et al. · Molecular medicine reports

Added to ASH registry: 2026-05-27

Genomics & Proteomics2015PMID 26354932

The Insect Chemoreceptor Superfamily Is Ancient in Animals

Robertson HM · Chemical senses

Added to ASH registry: 2026-05-27

Genomics & Proteomics2015PMID 26659921

Timing and Scope of Genomic Expansion within Annelida: Evidence from Homeoboxes in the Genome of the Earthworm Eisenia fetida

Zwarycz AS et al. · Genome biology and evolution

Added to ASH registry: 2026-05-27

Genomics & Proteomics2015PMID 26363292

Transcripts involved in hemostasis: exploring salivary complexes from Haementeria vizottoi leeches through transcriptomics

Amorim AM et al. · Toxicon

Added to ASH registry: 2026-05-27

Safety & Infection Control2015PMID 26284048

Identification of iron and heme utilization genes in Aeromonas and their role in the colonization of the leech digestive tract

Maltz M, LeVarge BL, Graf J · Frontiers in microbiology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2015PMID 25563920

Mucinivorans hirudinis gen. nov., sp. nov., an anaerobic, mucin-degrading bacterium isolated from the digestive tract of the medicinal leech Hirudo verbana

Nelson MC, Bomar L, Maltz M, Graf J · International journal of systematic and evolutionary microbiology

Added to ASH registry: 2026-05-26

Safety & Infection Control2015PMID 26635240

Reciprocal immune benefit based on complementary production of antibiotics by the leech Hirudo verbana and its gut symbiont Aeromonas veronii

Tasiemski A et al. · Scientific reports

Added to ASH registry: 2026-05-26

Genomics & Proteomics2015PMID 26054852

The venomous cocktail of the vampire snail Colubraria reticulata (Mollusca, Gastropoda)

Modica MV et al. · BMC genomics

Added to ASH registry: 2026-05-26

Salivary Pharmacology2015PMID 26636582

Effects of Carbon Nanotube Environmental Dispersion on an Aquatic Invertebrate, Hirudo medicinalis

Girardello R et al. · PloS one

Added to ASH registry: 2026-03-18

Antimicrobial Resistance2014PMID 24631579

A novel Toll like receptor with two TIR domains (HcToll-2) is involved in regulation of antimicrobial peptide gene expression of Hyriopsis cumingii.

Ren Q et al. · Developmental and comparative immunology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2014PMID 24747831

Calreticulin contributes to C1q-dependent recruitment of microglia in the leech Hirudo medicinalis following a CNS injury

Le et al. · Medical science monitor : international medical journal of experimental and clinical research

Added to ASH registry: 2026-05-28

Genomics & Proteomics2014PMID 25690960

Developmental biology of the leech Helobdella.

Weisblat et al. · The International journal of developmental biology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2014PMID 24663063

Differences in the gene expression profiles of haemocytes from schistosome-susceptible and -resistant biomphalaria glabrata exposed to Schistosoma mansoni excretory-secretory products.

Zahoor Z et al. · PloS one

Added to ASH registry: 2026-05-28

Genomics & Proteomics2014PMID 25105488

High diversity of bacterial pathogens and antibiotic resistance in salmonid fish farm pond water as determined by molecular identification employing 16S rDNA PCR, gene sequencing and total antibiotic susceptibility techniques

Moore et al. · Ecotoxicology and environmental safety

Added to ASH registry: 2026-05-28

Clinical Trials2014PMID 24739277

Inherited Thrombophilia.

Phillippe HM et al. · Journal of pharmacy practice

Added to ASH registry: 2026-05-28

Salivary Pharmacology2014PMID 25467079

Multiple inhibitory kinetics reveal an allosteric interplay among thrombin functional sites.

Zavyalova E et al. · Thrombosis research

Added to ASH registry: 2026-05-28

Clinical Trials2014PMID 24444877

Polyphenol compounds belonging to flavonoids inhibit activity of coagulation factor X.

Bijak M et al. · International journal of biological macromolecules

Added to ASH registry: 2026-05-28

Genomics & Proteomics2014PMID 24465907

Scanning behavior in the medicinal leech Hirudo verbana

Harley et al. · PloS one

Added to ASH registry: 2026-05-28

Salivary Pharmacology2014PMID 24635452

Targeting the GPIbα binding site of thrombin to simultaneously induce dual anticoagulant and antiplatelet effects.

Mehta AY et al. · Journal of medicinal chemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics2014PMID 25185664

Viral infection risks for patients using the finished product Hirudo verbana (medicinal leech)

von et al. · Parasitology research

Added to ASH registry: 2026-05-28

Genomics & Proteomics2014PMID 24701247

Chinese herbal medicine for aspirin resistance: a systematic review of randomized controlled trials

Liu AJ et al. · Evidence-based complementary and alternative medicine : eCAM

Added to ASH registry: 2026-05-27

Genomics & Proteomics2014PMID 24521495

Complete mitochondrial genome of Hirudo nipponia (Annelida, Hirudinea)

Yan H et al. · Mitochondrial DNA

Added to ASH registry: 2026-05-27

Drug Development2014PMID 24604304

Direct thrombin inhibitors: patents 2002-2012

Kong Y et al. · Molecular medicine reports

Added to ASH registry: 2026-05-27

Genomics & Proteomics2014PMID 25544958

Genetic diversity of freshwater leeches in Lake Gusinoe, Eastern Siberia, Russia

Kaygorodova IA et al. · TheScientificWorldJournal

Added to ASH registry: 2026-05-27

Genomics & Proteomics2014PMID 25059557

Hitchhiking of host biology by beneficial symbionts enhances transmission

Ott BM et al. · Scientific reports

Added to ASH registry: 2026-05-27

Genomics & Proteomics2014PMID 24860552

Metagenomic analysis of the medicinal leech gut microbiota

Maltz MA et al. · Frontiers in microbiology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2014PMID 24902753

Multiplexed modulation of behavioral choice (leech Hirudo verbana)

Palmer CR et al. · Journal of Experimental Biology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2014PMID 24572887

Characterization of the digestive tract microbiota of Hirudo orientalis (medicinal leech) and antibiotic resistance profile

Whitaker IS, Maltz M, Siddall ME, Graf J · Plastic and reconstructive surgery

Added to ASH registry: 2026-05-26

Genomics & Proteomics2014PMID 24747305

Determination of disulfide linkages in antimicrobial peptides of the macin family by combination of top-down and bottom-up proteomics

Hung CW, Jung S, Grötzinger J, Gelhaus C, Leippe M, Tholey A · Journal of proteomics

Added to ASH registry: 2026-05-26

Genomics & Proteomics2014PMID 24667183

High-yield novel leech hyaluronidase to expedite the preparation of specific hyaluronan oligomers

Jin P et al. · Scientific reports

Added to ASH registry: 2026-03-18

Genomics & Proteomics2014PMID 24723370

Microglia of medicinal leech (Hirudo medicinalis) express a specific activation marker homologous to vertebrate ionized calcium-binding adapter molecule 1 (Iba1/alias aif-1)

Drago F et al. · Developmental neurobiology

Added to ASH registry: 2026-03-18

Antimicrobial Resistance2013PMID 23666709

Age-dependent expression of stress and antimicrobial genes in the hemocytes and siphon tissue of the Antarctic bivalve, Laternula elliptica, exposed to injury and starvation.

Husmann G et al. · Cell stress & chaperones

Added to ASH registry: 2026-05-28

Genomics & Proteomics2013PMID 24217283

Differential expression of conserved germ line markers and delayed segregation of male and female primordial germ cells in a hermaphrodite, the leech helobdella

Cho SJ et al. · Molecular biology and evolution

Added to ASH registry: 2026-05-28

Salivary Pharmacology2013PMID 25232620

Erpobdellid leeches (Annelida, Clitellata, Hirudinida) from Tunisia: new records with the description of a new Trocheta species.

Ben Ahmed R et al. · Zootaxa

Added to ASH registry: 2026-05-28

Genomics & Proteomics2013PMID 24007384

Evolution of clitellate phaosomes from rhabdomeric photoreceptor cells of polychaetes - a study in the leech Helobdella robusta (Annelida, Sedentaria, Clitellata)

Döring C et al. · Frontiers in zoology

Added to ASH registry: 2026-05-28

Clinical Trials2013PMID 23675803

Factor V leiden thrombophilia in a female collegiate soccer athlete: a case report.

Erickson K et al. · Journal of athletic training

Added to ASH registry: 2026-05-28

Salivary Pharmacology2013PMID 24215622

Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition.

Roddick LA et al. · BMC biochemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics2013PMID 23355252

Involvement of nitric oxide through endocannabinoids release in microglia activation during the course of CNS regeneration in the medicinal leech.

Arafah K et al. · Glia

Added to ASH registry: 2026-05-28

Clinical Trials2013PMID 23216127

Prevalence of inherited antithrombin, protein C, and protein S deficiencies in portal vein system thrombosis and Budd-Chiari syndrome: a systematic review and meta-analysis of observational studies.

Qi X et al. · Journal of gastroenterology and hepatology

Added to ASH registry: 2026-05-28

Clinical Trials2013PMID 24335247

Prevalence of the Factor V E666D Mutation and Its Correlation With Activated Protein C Resistance in the Chinese Population.

Xin-Guang C et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Added to ASH registry: 2026-05-28

Clinical Trials2013PMID 25332562

Protein C deficiency.

De AK et al. · Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion

Added to ASH registry: 2026-05-28

Genomics & Proteomics2013PMID 23878582

The leech nervous system: a valuable model to study the microglia involvement in regenerative processes.

Le Marrec-Croq F et al. · Clinical & developmental immunology

Added to ASH registry: 2026-05-28

Safety & Infection Control2013PMID 24092791

Draft Genome Sequence of Aeromonas veronii Hm21, a Symbiotic Isolate from the Medicinal Leech Digestive Tract

Bomar L et al. · Genome announcements

Added to ASH registry: 2026-05-27

Drug Development2013PMID 24144055

Evaluation of a multifunctional staphylokinase variant with thrombin inhibition and antiplatelet aggregation activities produced from salt-inducible E. coli GJ1158

Kumar A et al. · Canadian Journal of Physiology and Pharmacology

Added to ASH registry: 2026-05-27

Safety & Infection Control2013PMID 24287596

First isolation of a giant virus from wild Hirudo medicinalis leech: Mimiviridae isolation in Hirudo medicinalis

Boughalmi M et al. · Viruses

Added to ASH registry: 2026-05-27

Drug Development2013PMID 23430245

Long-range electrostatic complementarity governs substrate recognition by human chymotrypsin C, a key regulator of digestive enzyme activation

Batra J et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-27

Genomics & Proteomics2013PMID 24085568

Spatial regulation dominates gene function in the ganglia chain

Hibsh D et al. · Bioinformatics (Oxford, England)

Added to ASH registry: 2026-05-27

Genomics & Proteomics2013PMID 23496873

The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand

Boyle AJ et al. · BMC biochemistry

Added to ASH registry: 2026-05-27

Genomics & Proteomics2013PMID 23446703

Devosia epidermidihirudinis sp. nov. isolated from the surface of a medical leech

Galatis H, Martin K, Kämpfer P, Glaeser SP · Antonie van Leeuwenhoek

Added to ASH registry: 2026-05-26

Genomics & Proteomics2013PMID 23315416

Flavobacterium cutihirudinis sp. nov., isolated from the skin of the medical leech Hirudo verbana

Glaeser SP, Galatis H, Martin K, Kämpfer P · International journal of systematic and evolutionary microbiology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2013PMID 23456803

Kaistia hirudinis sp. nov., isolated from the skin of Hirudo verbana

Glaeser SP, Galatis H, Martin K, Kämpfer P · International journal of systematic and evolutionary microbiology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2013PMID 23543503

Niabella hirudinis and Niabella drilacis sp. nov., isolated from the medicinal leech Hirudo verbana

Glaeser SP, Galatis H, Martin K, Kämpfer P · International journal of systematic and evolutionary microbiology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2013PMID 23625511

Operculum ultrastructure in leech cocoons

Rossi AM et al. · Journal of morphology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2013PMID 23308261

Differentially expressed genes in Hirudo medicinalis ganglia after acetyl-L-carnitine treatment

Federighi G et al. · PloS one

Added to ASH registry: 2026-03-18

Genomics & Proteomics2012PMID 22348050

Genome-wide identification and immune response analysis of serine protease inhibitor genes in the silkworm, Bombyx mori

Zhao et al. · PloS one

Added to ASH registry: 2026-05-28

Genomics & Proteomics2012PMID 22587329

Identification of 3'UTR sequence elements and a teloplasm localization motif sufficient for the localization of Hro-twist mRNA to the zygotic animal and vegetal poles.

Farooq M et al. · Development, growth & differentiation

Added to ASH registry: 2026-05-28

Genomics & Proteomics2012PMID 23254933

Insights into bilaterian evolution from three spiralian genomes.

Simakov O et al. · Nature

Added to ASH registry: 2026-05-28

Genomics & Proteomics2012PMID 22552629

Luteolibacter cuticulihirudinis sp. nov., isolated from Hirudo medicinalis

Glaeser et al. · Antonie van Leeuwenhoek

Added to ASH registry: 2026-05-28

Genomics & Proteomics2012PMID 22538479

Molluscan neurons in culture: shedding light on synapse formation and plasticity.

Schmold N et al. · Journal of molecular histology

Added to ASH registry: 2026-05-28

Clinical Trials2012PMID 23026651

Oral contraception in women with mild thrombophilia: what have we learned recently?

Blanco-Molina & · Thrombosis research

Added to ASH registry: 2026-05-28

Genomics & Proteomics2012PMID 22081719

Pseudarcicella hirudinis gen. nov., sp. nov., isolated from the skin of the medical leech Hirudo medicinalis

Kämpfer et al. · International journal of systematic and evolutionary microbiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2012PMID 22080112

Shrimp invertebrate lysozyme i-lyz: gene structure, molecular model and response of c and i lysozymes to lipopolysaccharide (LPS)

PeregrinoUriarte et al. · Fish & shellfish immunology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2012PMID 22768275

Transcriptome analysis of the Octopus vulgaris central nervous system

Zhang X et al. · PloS one

Added to ASH registry: 2026-05-28

Safety & Infection Control2012PMID 22572874

Bacterial symbioses of the medicinal leech Hirudo verbana

Nelson MC, Graf J · Gut microbes

Added to ASH registry: 2026-05-27

Genomics & Proteomics2012PMID 22792720

Biotechnological production of recombinant analogs of hirudin-1 from Hirudo medicinalis

Kostromina MA et al. · Bioorganicheskaia khimiia

Added to ASH registry: 2026-05-27

Genomics & Proteomics2012PMID 22792727

Catalytic sites of medicinal leech enzyme destabilase-lysozyme (Mldl). Structure-functional correlation

Zavalova LL et al. · Bioorganicheskaia khimiia

Added to ASH registry: 2026-05-27

Salivary Pharmacology2012PMID 22778902

Disintegrins from hematophagous sources

Assumpcao TC et al. · Toxins (Basel)

Added to ASH registry: 2026-05-27

Genomics & Proteomics2012PMID 22523161

Castellaniella hirudinis sp. nov., isolated from the skin of Hirudo verbana

Glaeser SP, Galatis H, Martin K, Kämpfer P · International journal of systematic and evolutionary microbiology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2012PMID 22342869

Phylogeny and phylogeography of medicinal leeches (genus Hirudo): fast dispersal and shallow genetic structure

Trontelj P, Utevsky SY · Molecular phylogenetics and evolution

Added to ASH registry: 2026-05-26

Genomics & Proteomics2012PMID 22358128

The medicinal leech genome encodes 21 innexin genes: different combinations are expressed by identified central neurons

Kandarian B et al. · Development genes and evolution

Added to ASH registry: 2026-05-26

Genomics & Proteomics2012PMID 22572874

Bacterial symbioses of the medicinal leech Hirudo verbana

Nelson M, Graf J · Gut microbes

Added to ASH registry: 2026-03-18

Genomics & Proteomics2012PMID 22532303

The Hirudo medicinalis species complex

Kutschera U · Die Naturwissenschaften

Added to ASH registry: 2026-03-18

Genomics & Proteomics2011PMID 21846345

Annelid Distal-less/Dlx duplications reveal varied post-duplication fates.

McDougall C et al. · BMC evolutionary biology

Added to ASH registry: 2026-05-28

Clinical Trials2011PMID 21455861

Factor V Leiden in women: a thrombotic risk factor or an evolutionary advantage?

Franchini M et al. · Seminars in thrombosis and hemostasis

Added to ASH registry: 2026-05-28

Clinical Trials2011PMID 22082521

Hypercoagulable states.

Anderson JAM et al. · Critical care clinics

Added to ASH registry: 2026-05-28

Genomics & Proteomics2011PMID 21526169

Multiple changes in peptide and lipid expression associated with regeneration in the nervous system of the medicinal leech.

Meriaux et al. · PloS one

Added to ASH registry: 2026-05-28

Genomics & Proteomics2011PMID 21241702

Neuropeptide evolution: neurohormones and neuropeptides predicted from the genomes of Capitella teleta and Helobdella robusta.

Veenstra JA · General and comparative endocrinology

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2011PMID 22132238

Phylogenomics of Reichenowia parasitica, an alphaproteobacterial endosymbiont of the freshwater leech Placobdella parasitica.

Kvist S et al. · PloS one

Added to ASH registry: 2026-05-28

Genomics & Proteomics2011PMID 21561963

Serotonin modulates muscle function in the medicinal leech Hirudo verbana

Gerry et al. · Biology letters

Added to ASH registry: 2026-05-28

Genomics & Proteomics2011PMID 21212033

The complete mitochondrial genome sequence of Whitmania pigra (Annelida, Hirudinea): the first representative from the class Hirudinea

Shen et al. · Comparative biochemistry and physiology. Part D, Genomics & proteomics

Added to ASH registry: 2026-05-28

Safety & Infection Control2011PMID 21359176

Complex evolutionary history of the Aeromonas veronii group revealed by host interaction and DNA sequence data

Silver AC et al. · PLoS One

Added to ASH registry: 2026-05-27

Genomics & Proteomics2011PMID 21500820

Highly sensitive potentiometric strip test for detecting high charge density impurities in heparin

Kang Y et al. · Analytical chemistry

Added to ASH registry: 2026-05-27

Genomics & Proteomics2011PMID 22461860

Innate and procured immunity inside the digestive tract of the medicinal leech

Silver A et al. · Invertebrate survival journal : ISJ

Added to ASH registry: 2026-05-27

Genomics & Proteomics2011PMID 22629601

Lysozyme activity of the salivary gland secretion of the medicinal leech H. verbana, H. medicinalis and H. orientalis

Baskova IP et al. · Biomeditsinskaia khimiia

Added to ASH registry: 2026-05-27

Genomics & Proteomics2011PMID 21368831

Phylogenomic analyses unravel annelid evolution

Struck TH et al. · Nature

Added to ASH registry: 2026-05-27

Safety & Infection Control2011PMID 21097598

The type II secretion system is essential for erythrocyte lysis and gut colonization by the leech digestive tract symbiont Aeromonas veronii

Maltz M et al. · Applied and environmental microbiology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2011PMID 21467263

Directed culturing of microorganisms using metatranscriptomics

Bomar L, Maltz M, Colston S, Graf J · mBio

Added to ASH registry: 2026-05-26

Salivary Pharmacology2011PMID 22198928

[Medicinal leeches and hirudotherapy]

Gödekmerdan A et al. · Turkiye parazitolojii dergisi

Added to ASH registry: 2026-03-18

Genomics & Proteomics2011PMID 22069059

Small bite, large impact-saliva and salivary molecules in the medicinal leech, Hirudo medicinalis

Hildebrandt J, Lemke S · Die Naturwissenschaften

Added to ASH registry: 2026-03-18

Genomics & Proteomics2010PMID 19682590

A new species of Haemopis (Annelida: Hirudinea): evolution of North American terrestrial leeches

Wirchansky et al. · Molecular phylogenetics and evolution

Added to ASH registry: 2026-05-28

Genomics & Proteomics2010PMID 20934425

Ecdysone receptor homologs from mollusks, leeches and a polychaete worm.

Laguerre M et al. · FEBS letters

Added to ASH registry: 2026-05-28

Genomics & Proteomics2010PMID 20176615

Evolutionary dynamics of the wnt gene family: a lophotrochozoan perspective.

Cho et al. · Molecular biology and evolution

Added to ASH registry: 2026-05-28

Clinical Trials2010PMID 20483158

The antithrombotic effect of a novel hirudin derivative after reconstruction of carotid artery in rabbits.

Lu WF et al. · Thrombosis research

Added to ASH registry: 2026-05-28

Genomics & Proteomics2010PMID 20363282

A novel trypsin Kazal-type inhibitor from Aedes aegypti with thrombin coagulant inhibitory activity

Watanabe RM et al. · Biochimie

Added to ASH registry: 2026-05-27

Safety & Infection Control2010PMID 21171864

Barcoding, types and the Hirudo files: using information content to critically evaluate the identity of DNA barcodes

Kvist S et al. · Mitochondrial DNA

Added to ASH registry: 2026-05-27

Drug Development2010PMID 21077838

Destabilase-lysozyme of medicinal leech. Multifunctionality of recombinant protein

Zavalova LL et al. · Biochemistry (Mosc)

Added to ASH registry: 2026-05-27

Genomics & Proteomics2010PMID 21271855

DNA barcoding reveals Mexican diversity within the freshwater leech genus Helobdella

Oceguera-Figueroa A et al. · Mitochondrial DNA

Added to ASH registry: 2026-05-27

Genomics & Proteomics2010PMID 20880845

Flexibility of the thrombin-activatable fibrinolysis inhibitor pro-domain enables productive binding of protein substrates

Valnickova Z et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-27

Genomics & Proteomics2010PMID 21429133

Genetic barcoding of marine leeches (Ozobranchus spp.) from Florida sea turtles and their divergence in host specificity

McGowin AE et al. · Molecular ecology resources

Added to ASH registry: 2026-05-27

Genomics & Proteomics2010PMID 20632937

Protein-lipid particles of medicinal leech salivary gland secretion; their size and morphology

Baskova IP et al. · Biochemistry. Biokhimiia

Added to ASH registry: 2026-05-27

Genomics & Proteomics2010PMID 21158638

Salivary transcriptome of the North American medicinal leech, Macrobdella decora

Min GS et al. · The Journal of parasitology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2010PMID 20650303

A novel RGD-toxin protein, Lj-RGD3, from the buccal gland secretion of Lampetra japonica impacts diverse biological activities

Wang J et al. · Biochimie

Added to ASH registry: 2026-05-26

Genomics & Proteomics2010PMID 20579359

Construction of a medicinal leech transcriptome database and its application to the identification of leech homologs of neural and innate immune genes

Macagno E et al. · BMC genomics

Added to ASH registry: 2026-03-18

Salivary Pharmacology2010PMID 20035779

Platelet aggregation inhibitors from hematophagous animals

Francischetti I · Toxicon : official journal of the International Society on Toxinology

Added to ASH registry: 2026-03-18

Genomics & Proteomics2010PMID 20680601

Specific MALDI-MSI: Tag-Mass

Stauber J et al. · Methods in molecular biology (Clifton, N.J.)

Added to ASH registry: 2026-03-18

Drug Development2010PMID 20709502

Surface modification with PEG and hirudin for protein resistance and thrombin neutralization in blood contact

Alibeik S, Zhu S, Brash J · Colloids and surfaces. B, Biointerfaces

Added to ASH registry: 2026-03-18

Antimicrobial Resistance2009PMID 19447331

Characterization of an i-type lysozyme gene from the sea cucumber Stichopus japonicus, and enzymatic and nonenzymatic antimicrobial activities of its recombinant protein.

Cong L et al. · Journal of bioscience and bioengineering

Added to ASH registry: 2026-05-28

Genomics & Proteomics2009PMID 19917687

Deciphering the immune function and regulation by a TLR of the cytokine EMAPII in the lesioned central nervous system using a leech model

Schikorski et al. · Journal of immunology (Baltimore, Md. : 1950)

Added to ASH registry: 2026-05-28

Genomics & Proteomics2009PMID 19747476

Grandparental stem cells in leech segmentation: differences in CDC42 expression are correlated with an alternating pattern of blast cell fates.

Zhang et al. · Developmental biology

Added to ASH registry: 2026-05-28

Salivary Pharmacology2009PMID 19589779

Long range communication between exosites 1 and 2 modulates thrombin function.

Petrera NS et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2009PMID 19405965

Transcriptomic analysis of the entomopathogenic nematode Heterorhabditis bacteriophora TTO1.

Bai X et al. · BMC genomics

Added to ASH registry: 2026-05-28

Genomics & Proteomics2009PMID 19447298

Use of scanning ion conductance microscopy to guide and redirect neuronal growth cones.

Pellegrino M et al. · Neuroscience research

Added to ASH registry: 2026-05-28

Antimicrobial Resistance2009PMID 19454335

Identification and cloning of an invertebrate-type lysozyme from Eisenia andrei

Joskova R et al. · Developmental and comparative immunology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2009PMID 19811660

Poly-paraphyly of Hirudinidae: many lineages of medicinal leeches

Phillips AJ, Siddall ME · BMC evolutionary biology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2009PMID 19409897

Protective effects of microglia in multiple sclerosis

Napoli I, Neumann H · Experimental neurology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2009PMID 19678832

Stratified bacterial community in the bladder of the medicinal leech, Hirudo verbana

Kikuchi Y, Bomar L, Graf J · Environmental microbiology

Added to ASH registry: 2026-05-26

Clinical Trials2009PMID 20141667

[Leech hirudo medicinalis: a therapeutic alternative available in Mexico]

Cornejo-Esquerra A et al. · Revista medica del Instituto Mexicano del Seguro Social

Added to ASH registry: 2026-03-18

Clinical Trials2009PMID 19998801

[Medicinal leeches]

Massart D, Sohawon S, Noordally O · Revue medicale de Bruxelles

Added to ASH registry: 2026-03-18

Clinical Trials2009PMID 19325315

Leech therapy

Yantis M, O'Toole K, Ring P · The American journal of nursing

Added to ASH registry: 2026-03-18

Clinical Trials2008PMID 18493021

Computational study of the putative active form of protein Z (PZa): sequence design and structural modeling.

Chandrasekaran V et al. · Protein science : a publication of the Protein Society

Added to ASH registry: 2026-05-28

Salivary Pharmacology2008PMID 18779330

Fibrinogen-elongated gamma chain inhibits thrombin-induced platelet response, hindering the interaction with different receptors.

Lancellotti S et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-28

Safety & Infection Control2008PMID 18996625

On designing non-saccharide, allosteric activators of antithrombin.

Raghuraman A et al. · European journal of medicinal chemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics2008PMID 18250335

Structural identification of the pathway of long-range communication in an allosteric enzyme.

Gandhi PS et al. · Proceedings of the National Academy of Sciences of the United States of America

Added to ASH registry: 2026-05-28

Genomics & Proteomics2008PMID 19017802

Transcriptome analysis and identification of regulators for long-term plasticity in Aplysia kurodai

Lee et al. · Proceedings of the National Academy of Sciences of the United States of America

Added to ASH registry: 2026-05-28

Genomics & Proteomics2008PMID 18722350

Trichoplax, the simplest known animal, contains an estrogen-related receptor but no estrogen receptor: Implications for estrogen receptor evolution.

Baker ME · Biochemical and biophysical research communications

Added to ASH registry: 2026-05-28

Clinical Trials2008PMID 18257025

Update on atrial fibrillation: part I.

Savelieva I et al. · Clinical cardiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2008PMID 18998199

A novel hirudin derivative characterized with anti-platelet aggregations and thrombin inhibition

Mo W et al. · Journal of thrombosis and thrombolysis

Added to ASH registry: 2026-05-27

Salivary Pharmacology2008PMID 18393768

Proteins and peptides of the salivary gland secretion of medicinal leeches Hirudo verbana, H. medicinalis, and H. orientalis

Baskova IP et al. · Biochemistry. Biokhimiia

Added to ASH registry: 2026-05-27

Genomics & Proteomics2008PMID 18393768

Proteins and peptides of the salivary gland secretion of medicinal leeches Hirudo verbana, H. medicinalis, and H. orientalis

Baskova IP et al. · Biochemistry (Moscow)

Added to ASH registry: 2026-05-27

Genomics & Proteomics2008PMID 18775546

Cell dynamics during cocoon secretion in the aquatic leech, Theromyzon tessulatum

Sayers CW, Coleman J, Shain DH · Tissue & cell

Added to ASH registry: 2026-05-26

Genomics & Proteomics2008PMID 18689513

Characterization of the digestive-tract microbiota of Hirudo orientalis, a european medicinal leech

Laufer AS, Siddall ME, Graf J · Applied and environmental microbiology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2007PMID 17277211

Spatial and temporal population dynamics of a naturally occurring two-species microbial community inside the digestive tract of the medicinal leech

Kikuchi et al. · Applied and environmental microbiology

Added to ASH registry: 2026-05-29

Genomics & Proteomics2007PMID 17912744

Atypical embryonic synapses fail to regenerate in adulthood.

Kloos AD et al. · The Journal of comparative neurology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2007PMID 17526846

Characterization of a catalase gene from Aeromonas veronii, the digestive-tract symbiont of the medicinal leech

Rio et al. · Microbiology (Reading, England)

Added to ASH registry: 2026-05-28

Genomics & Proteomics2007PMID 18062812

Characterization of a human coagulation factor Xa-binding site on Viperidae snake venom phospholipases A2 by affinity binding studies and molecular bioinformatics.

Faure G et al. · BMC structural biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2007PMID 17606903

Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4.

Bah A et al. · Proceedings of the National Academy of Sciences of the United States of America

Added to ASH registry: 2026-05-28

Genomics & Proteomics2007PMID 17114316

Novel role for Aeromonas jandaei as a digestive tract symbiont of the North American medicinal leech

Siddall et al. · Applied and environmental microbiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2007PMID 17123088

Postactivation inhibition of spontaneously active neurosecretory neurons in the medicinal leech.

Gocht et al. · Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2007PMID 17480028

Reduced axon sprouting after treatment that diminishes microglia accumulation at lesions in the leech CNS.

Ngu et al. · The Journal of comparative neurology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2007PMID 17367301

Proteomic analysis methods for characterization of proteins from the salivary gland secretions of the medicinal leech during different seasons

Baskova IP et al. · Biochemistry. Biokhimiia

Added to ASH registry: 2026-05-27

Salivary Pharmacology2007PMID 17367301

Proteomic analysis methods for characterization of proteins from the salivary gland secretions of the medicinal leech during different seasons

Baskova IP et al. · Biochemistry. Biokhimiia

Added to ASH registry: 2026-05-27

Genomics & Proteomics2007PMID 18164761

Toll-like receptor genes (TLRs) from Capitella capitata and Helobdella robusta (Annelida)

Davidson CR et al. · Developmental and comparative immunology

Added to ASH registry: 2026-05-27

Safety & Infection Control2007PMID 17616592

Identification of Aeromonas veronii genes required for colonization of the medicinal leech, Hirudo verbana

Silver AC et al. · Journal of bacteriology

Added to ASH registry: 2026-05-26

Salivary Pharmacology2007PMID 17490558

[Research progress in hirudin fusion protein--review]

Zhang C et al. · Zhongguo shi yan xue ye xue za zhi

Added to ASH registry: 2026-03-18

Genomics & Proteomics2007PMID 17426015

Diverse molecular data demonstrate that commercially available medicinal leeches are not Hirudo medicinalis

Siddall M et al. · Proceedings. Biological sciences

Added to ASH registry: 2026-03-18

Drug Development2007PMID 17598001

Hirudin--the long and stony way from an anticoagulant peptide in the saliva of medicinal leech to a recombinant drug and beyond. A historical piece

Nowak G, Schrör K · Thrombosis and haemostasis

Added to ASH registry: 2026-03-18

Genomics & Proteomics2006PMID 17075704

Activity-dependent suppression of spontaneous spike generation in the Retzius neurons of the leech Hirudo medicinalis L.

Rose et al. · Invertebrate neuroscience : IN

Added to ASH registry: 2026-05-28

Clinical Trials2006PMID 16781211

Argatroban: update.

Yeh RW et al. · American heart journal

Added to ASH registry: 2026-05-28

Genomics & Proteomics2006PMID 16621955

Beyond the central pattern generator: amine modulation of decision-making neural pathways descending from the brain of the medicinal leech.

Crisp et al. · The Journal of experimental biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2006PMID 17022642

Detection of noncovalent complexes in biological samples by intensity fading and high-mass detection MALDI-TOF mass spectrometry

Yanes et al. · Journal of proteome research

Added to ASH registry: 2026-05-28

Clinical Trials2006PMID 16637459

Emerging anticoagulants: mechanism of action and future potential.

Klement P et al. · Vnitrni lekarstvi

Added to ASH registry: 2026-05-28

Genomics & Proteomics2006PMID 16930584

Maternal expression of a NANOS homolog is required for early development of the leech Helobdella robusta.

Agee et al. · Developmental biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2006PMID 16440200

Molecular characterization and embryonic expression of innexins in the leech Hirudo medicinalis

Dykes IM et al. · Development genes and evolution

Added to ASH registry: 2026-05-28

Genomics & Proteomics2006PMID 17073933

Lessons from leeches: a call for DNA barcoding in the lab

Bely AE, Weisblat DA · Evolution & Development

Added to ASH registry: 2026-05-27

Genomics & Proteomics2006PMID 16523290

Structural model of an antistasin/notch-like fusion protein from the cocoon wall of the aquatic leech, Theromyzon tessulatum

Mason TA et al. · J Mol Model

Added to ASH registry: 2026-05-27

Genomics & Proteomics2006PMID 16820471

Culture-independent characterization of the digestive-tract microbiota of the medicinal leech reveals a tripartite symbiosis

Worthen PL, Gode CJ, Graf J · Applied and environmental microbiology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2006PMID 16843660

Leeches and their microbiota: naturally simple symbiosis models

Graf J, Kikuchi Y, Rio RV · Trends in microbiology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2006PMID 16888763

Proteome modifications of the medicinal leech nervous system under bacterial challenge

Vergote D et al. · Proteomics

Added to ASH registry: 2026-05-26

Genomics & Proteomics2006PMID 16621015

Characterizations of Hirudo medicinalis DNA promoters for targeted gene expression

Baker M, Macagno E · Journal of neuroscience methods

Added to ASH registry: 2026-03-18

Genomics & Proteomics2006PMID 16623399

Molecular requirements for the colonization of Hirudo medicinalis by Aeromonas veronii

Graf J · Progress in molecular and subcellular biology

Added to ASH registry: 2026-03-18

Genomics & Proteomics2005PMID 16261357

A new species of the medicinal leech (Oligochaeta, Hirudinida, Hirudo) from Transcaucasia and an identification key for the genus Hirudo

Utevsky et al. · Parasitology research

Added to ASH registry: 2026-05-28

Genomics & Proteomics2005PMID 15788451

Applications of mRNA injections for analyzing cell lineage and asymmetric cell divisions during segmentation in the leech Helobdella robusta.

Zhang et al. · Development (Cambridge, England)

Added to ASH registry: 2026-05-28

Salivary Pharmacology2005PMID 16155118

Chemical synthesis of the RGD-protein decorsin: Pro-->Ala replacement reduces protein thermostability.

Frare E et al. · Protein engineering, design & selection : PEDS

Added to ASH registry: 2026-05-28

Clinical Trials2005PMID 15855479

Factor V Leiden and its effect on children with cardiac pathology.

Connor JA · Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses

Added to ASH registry: 2026-05-28

Genomics & Proteomics2005PMID 15837518

Fibrinogen and fibrin.

Weisel · Advances in protein chemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics2005PMID 16030009

Functional screening of serine protease inhibitors in the medical leech Hirudo medicinalis monitored by intensity fading MALDI-TOF MS

Yanes et al. · Molecular & cellular proteomics : MCP

Added to ASH registry: 2026-05-28

Genomics & Proteomics2005PMID 16151107

New gammaproteobacteria associated with blood-feeding leeches and a broad phylogenetic analysis of leech endosymbionts

Perkins et al. · Applied and environmental microbiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2005PMID 15817228

Regeneration and asexual reproduction share common molecular changes: upregulation of a neural glycoepitope during morphallaxis in Lumbriculus

Martinez et al. · Mechanisms of development

Added to ASH registry: 2026-05-28

Genomics & Proteomics2005PMID 16047551

Repair and regeneration of functional synaptic connections: cellular and molecular interactions in the leech

Duan et al. · Cellular and molecular neurobiology

Added to ASH registry: 2026-05-28

Drug Development2005PMID 16002430

Studies on the basis for the properties of fibrin produced from fibrinogen-containing gamma' chains.

Siebenlist KR et al. · Blood

Added to ASH registry: 2026-05-28

Genomics & Proteomics2005PMID 16172883

Three-dimensional culture of leech and snail ganglia for studies of neural repair.

Babington EJ et al. · Invertebrate neuroscience : IN

Added to ASH registry: 2026-05-28

Genomics & Proteomics2005PMID 15708003

Transcriptome analysis in the midgut of the earthworm (Eisenia andrei) using expressed sequence tags

Lee et al. · Biochemical and biophysical research communications

Added to ASH registry: 2026-05-28

Genomics & Proteomics2005PMID 15969650

Protein mapping of the salivary complex from a hematophagous leech

Ricci-Silva ME et al. · OMICS

Added to ASH registry: 2026-05-27

Salivary Pharmacology2005PMID 15969650

Protein mapping of the salivary complex from a hematophagous leech

Ricci-Silva ME et al. · Omics : a journal of integrative biology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2005PMID 16047550

Hirudo medicinalis: a platform for investigating genes in neural repair

Wang W et al. · Cellular and molecular neurobiology

Added to ASH registry: 2026-03-18

Genomics & Proteomics2004PMID 14678834

Cloning and expression of a leech complexin

Dykes IM et al. · Gene expression patterns : GEP

Added to ASH registry: 2026-05-28

Salivary Pharmacology2004PMID 15116248

Penthalaris, a novel recombinant five-Kunitz tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick vector of Lyme disease, Ixodes scapularis.

Francischetti IM et al. · Thrombosis and haemostasis

Added to ASH registry: 2026-05-28

Salivary Pharmacology2004PMID 15461140

Purification and identification of recombinant hirudin and its degradation products expressed in Pichia pastoris.

Zhou WB et al. · Preparative biochemistry & biotechnology

Added to ASH registry: 2026-05-28

Salivary Pharmacology2004PMID 15358856

Rational design and selection of bivalent peptide ligands of thrombin incorporating P4-P1 tetrapeptide sequences: from good substrates to potent inhibitors.

Su Z et al. · Protein engineering, design & selection : PEDS

Added to ASH registry: 2026-05-28

Genomics & Proteomics2004PMID 15258158

Up-regulation of neurohemerythrin expression in the central nervous system of the medicinal leech, Hirudo medicinalis, following septic injury

Vergote et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics2004PMID 15476200

Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: up-regulation by interleukin-1beta and glucocorticoids

Toh ML et al. · Arthritis and rheumatism

Added to ASH registry: 2026-05-27

Genomics & Proteomics2004PMID 15292227

Molecular mapping of the thrombin-heparin cofactor II complex

Fortenberry YM et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-27

Genomics & Proteomics2004PMID 15310277

Protein profiling of the medicinal leech salivary gland secretion by proteomic analytical methods

Baskova IP et al. · Biochemistry. Biokhimiia

Added to ASH registry: 2026-05-27

Salivary Pharmacology2004PMID 15310277

Protein profiling of the medicinal leech salivary gland secretion by proteomic analytical methods

Baskova IP et al. · Biochemistry. Biokhimiia

Added to ASH registry: 2026-05-27

Drug Development2004PMID 15310278

Recombinant destabilase-lysozyme: synthesis de novo in E. coli and action mechanism of the enzyme expressed in Spodoptera frugiperda

Zavalova LL et al. · Biochemistry (Mosc)

Added to ASH registry: 2026-05-27

Drug Development2004PMID 14706837

Two engineered eglin c mutants potently and selectively inhibiting kexin or furin

Liu Z et al. · FEBS letters

Added to ASH registry: 2026-05-27

Genomics & Proteomics2004PMID 15683933

Celebrity with a neglected taxonomy: molecular systematics of the medicinal leech (genus Hirudo)

Trontelj P, Utevsky SY · Molecular phylogenetics and evolution

Added to ASH registry: 2026-05-26

Salivary Pharmacology2004PMID 15102860

Molecular characterization of two novel antibacterial peptides inducible upon bacterial challenge in an annelid, the leech Theromyzon tessulatum

Tasiemski A, Vandenbulcke F, Mitta G, Lemoine J, Lefebvre C, Sautière PE, Salzet M · The Journal of biological chemistry

Added to ASH registry: 2026-05-26

Genomics & Proteomics2004PMID 15180533

Hirudo medicinalis: avascular tissues for clear-cut angiogenesis studies?

de Eguileor M et al. · Current pharmaceutical design

Added to ASH registry: 2026-03-18

Genomics & Proteomics2004PMID 14690474

Identifying genes for neuron survival and axon outgrowth in Hirudo medicinalis

Blackshaw S et al. · Journal of anatomy

Added to ASH registry: 2026-03-18

Genomics & Proteomics2003PMID 14645128

A distinct patterning mechanism of O and P cell fates in the development of the rostral segments of the leech Helobdella robusta: implications for the evolutionary dissociation of developmental pathway and morphological outcome.

Kuo et al. · Development (Cambridge, England)

Added to ASH registry: 2026-05-28

Genomics & Proteomics2003PMID 14638932

Activation of AMPA/kainate receptors but not acetylcholine receptors causes Mg2+ influx into Retzius neurones of the leech Hirudo medicinalis.

Muller et al. · The Journal of general physiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2003PMID 14523362

Chromacin-like peptide in leeches

Salzet M et al. · Neuro endocrinology letters

Added to ASH registry: 2026-05-27

Safety & Infection Control2003PMID 12839811

Complement resistance is essential for colonization of the digestive tract of Hirudo medicinalis by Aeromonas strains

Braschler TR et al. · Applied and environmental microbiology

Added to ASH registry: 2026-05-27

Genomics & Proteomics2003PMID 12788107

Multiple forms of medicinal leech destabilase-lysozyme

Zavalova LL et al. · Biochemical and biophysical research communications

Added to ASH registry: 2026-05-27

Genomics & Proteomics2003PMID 12620988

A hedgehog homolog regulates gut formation in leech (Helobdella)

Kang D et al. · Development (Cambridge, England)

Added to ASH registry: 2026-05-26

Genomics & Proteomics2003PMID 12973254

Hirudo medicinalis: the need for prophylactic antibiotics

Whitaker I, Elmiyeh B, Wright D · Plastic and reconstructive surgery

Added to ASH registry: 2026-03-18

Genomics & Proteomics2002PMID 11830572

Micromere lineages in the glossiphoniid leech Helobdella.

Huang et al. · Development (Cambridge, England)

Added to ASH registry: 2026-05-28

Genomics & Proteomics2002PMID 11965437

Phylogenetic analysis of invertebrate lysozymes and the evolution of lysozyme function

Bachali et al. · Journal of molecular evolution

Added to ASH registry: 2026-05-28

Genomics & Proteomics2002PMID 11921072

Secondary surgery after digit replantation: its incidence and sequence

Wang · Microsurgery

Added to ASH registry: 2026-05-28

Genomics & Proteomics2002PMID 12424288

Activity-dependent increase of the AHP amplitude in T sensory neurons of the leech

Scuri R, Mozzachiodi R, Brunelli M · Journal of neurophysiology

Added to ASH registry: 2026-05-26

Genomics & Proteomics2002PMID 12117817

Expression and function of an even-skipped homolog in the leech Helobdella robusta

Song MH et al. · Development (Cambridge, England)

Added to ASH registry: 2026-05-26

Drug Development2002PMID 12420236

Pharmacology of recombinant hirudin

Nowak G · Seminars in thrombosis and hemostasis

Added to ASH registry: 2026-03-18

Genomics & Proteomics2001PMID 11222292

Apparent intracellular Mg2+ buffering in neurons of the leech Hirudo medicinalis.

Günzel et al. · Biophysical journal

Added to ASH registry: 2026-05-28

Genomics & Proteomics2001PMID 11391646

Calcium transients in subcompartments of the leech Retzius neuron as induced by single action potentials.

Beck et al. · Journal of neurobiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics2001PMID 11466529

Dorsal and snail homologs in leech development.

Goldstein et al. · Development genes and evolution

Added to ASH registry: 2026-05-28

Genomics & Proteomics2001PMID 11290301

Establishment of segment polarity in the ectoderm of the leech Helobdella.

Seaver et al. · Development (Cambridge, England)

Added to ASH registry: 2026-05-28

Genomics & Proteomics2001PMID 11245916

Evidence for an endocannabinoid system in the central nervous system of the leech Hirudo medicinalis

Matias et al. · Brain research. Molecular brain research

Added to ASH registry: 2026-05-28

Genomics & Proteomics2001PMID 11812243

Separation of monomerizing and lysozyme activities of destabilase from medicinal leech salivary gland secretion

Baskova IP et al. · Biochemistry (Mosc)

Added to ASH registry: 2026-05-27

Genomics & Proteomics2001PMID 11584601

Hirudo medicinalis: the medicinal leech

Andrews S · The Journal of audiovisual media in medicine

Added to ASH registry: 2026-03-18

Genomics & Proteomics2000PMID 10719176

Destabilase from the medicinal leech is a representative of a novel family of lysozymes

Zavalova LL et al. · Biochimica et biophysica acta

Added to ASH registry: 2026-05-27

Genomics & Proteomics2000PMID 10974348

Modulation of clearance of recombinant serum albumin by either glycosylation or truncation

Sheffield WP et al. · Thrombosis research

Added to ASH registry: 2026-05-27

Genomics & Proteomics2000PMID 10837487

Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin

Shapiro MJ et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-27

Genomics & Proteomics2000PMID 10975565

Recombinant decorsin: dynamics of the RGD recognition site

Krezel AM et al. · Protein science : a publication of the Protein Society

Added to ASH registry: 2026-05-27

Genomics & Proteomics2000PMID 10852926

Therostasin, a novel clotting factor Xa inhibitor from the rhynchobdellid leech Theromyzon tessulatum

Chopin V et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-27

Salivary Pharmacology1999PMID 10420478

[Peptides as inhibitors of thrombin coagulation activity and of thrombocyte aggregation].

Pastorova VE et al. · Uspekhi fiziologicheskikh nauk

Added to ASH registry: 2026-05-28

Genomics & Proteomics1999PMID 10398075

Cellular expression of a leech netrin suggests roles in the formation of longitudinal nerve tracts and in regional innervation of peripheral targets

Gan et al. · Journal of neurobiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1999PMID 10577715

Phylogeny of the leech family Glossiphoniidae based on mitochondrial gene sequences and morphological data

Light et al. · The Journal of parasitology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1999PMID 10595640

A new factor Xa inhibitor (lefaxin) from the Haementeria depressa leech

Faria F et al. · Thrombosis and haemostasis

Added to ASH registry: 2026-05-27

Genomics & Proteomics1999PMID 10326760

Evidence that heparin but not hirudin reduces PAI-1 expression in cultured human endothelial cells

Orbe J et al. · Thrombosis research

Added to ASH registry: 2026-05-27

Genomics & Proteomics1999PMID 10380350

From natural to synthetic multisite thrombin inhibitors

Lombardi A et al. · Biopolymers

Added to ASH registry: 2026-05-27

Genomics & Proteomics1999PMID 10512718

Structure of the complex of the antistasin-type inhibitor bdellastasin with trypsin and modelling of the bdellastasin-microplasmin system

Rester U et al. · Journal of molecular biology

Added to ASH registry: 2026-05-27

Safety & Infection Control1999PMID 9864188

Symbiosis of Aeromonas veronii biovar sobria and Hirudo medicinalis, the medicinal leech: a novel model for digestive tract associations

Graf J · Infection and Immunity

Added to ASH registry: 2026-05-27

Safety & Infection Control1999PMID 9864188

Symbiosis of Aeromonas veronii biovar sobria and Hirudo medicinalis, the medicinal leech: a novel model for digestive tract associations

Graf J · Infection and immunity

Added to ASH registry: 2026-05-26

Salivary Pharmacology1998PMID 9749925

Binding of hirudin to meizothrombin

Fischer BE et al. · Protein engineering

Added to ASH registry: 2026-05-28

Genomics & Proteomics1998PMID 9872006

Injury-induced expression of endothelial nitric oxide synthase by glial and microglial cells in the leech central nervous system within minutes after injury

Shafer et al. · Proceedings. Biological sciences

Added to ASH registry: 2026-05-28

Genomics & Proteomics1998PMID 9479704

Phylogeny of leeches (Hirudinea) based on mitochondrial cytochrome c oxidase subunit I

Siddall et al. · Molecular phylogenetics and evolution

Added to ASH registry: 2026-05-28

Genomics & Proteomics1998PMID 9688284

Amino acid sequence of piguamerin, an antistasin-type protease inhibitor from the blood sucking leech Hirudo nipponia

Kim DR et al. · Eur J Biochem

Added to ASH registry: 2026-05-27

Genomics & Proteomics1998PMID 9578479

Bdellastasin, a serine protease inhibitor of the antistasin family from the medical leech

Moser M et al. · European journal of biochemistry

Added to ASH registry: 2026-05-27

Genomics & Proteomics1997PMID 9387880

Leech egg-laying-like hormone: structure, neuronal distribution and phylogeny

Salzet et al. · Brain research. Molecular brain research

Added to ASH registry: 2026-05-28

Genomics & Proteomics1997PMID 9006075

Planarian Hox genes: novel patterns of expression during regeneration.

Bayascas et al. · Development (Cambridge, England)

Added to ASH registry: 2026-05-28

Genomics & Proteomics1997PMID 9210403

Tridegin, a new peptidic inhibitor of factor XIIIa, from the blood-sucking leech Haementeria ghilianii

Finney S et al. · The Biochemical journal

Added to ASH registry: 2026-05-27

Genomics & Proteomics1997PMID 9783443

A subtractive cDNA library from an identified regenerating neuron is enriched in sequences up-regulated during nerve regeneration

Korneev S et al. · Invertebrate neuroscience : IN

Added to ASH registry: 2026-05-26

Genomics & Proteomics1997PMID 9236255

Regeneration of a central synapse restores nonassociative learning

Modney BK et al. · The Journal of neuroscience : the official journal of the Society for Neuroscience

Added to ASH registry: 2026-05-26

Genomics & Proteomics1996PMID 8691114

An increase in activity of serotonergic Retzius neurones may not be necessary for the consummatory phase of feeding in the leech Hirudo medicinalis.

Wilson et al. · The Journal of experimental biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1996PMID 8812580

Effects of an organophosphorus insecticide (Temephos) on gametogenesis in the leech Hirudinaria manillensis (Hirudinidae)

Singhal et al. · Journal of invertebrate pathology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1996PMID 8783019

Investigation on minor degraded derivatives of the recombinant hirudin variant HM2 from Hirudinaria manillensis isolated by isoelectric focusing in multicompartment electrolyzers

Bossi et al. · Electrophoresis

Added to ASH registry: 2026-05-28

Genomics & Proteomics1996PMID 8815196

Sodium-magnesium antiport in Retzius neurones of the leech Hirudo medicinalis.

Günzel et al. · The Journal of physiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1996PMID 8906337

The core domain of hirudin from the leech Hirudinaria manillensis. Chemical modification of a tryptophan-containing synthetic peptide analog

De et al. · Advances in experimental medicine and biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1996PMID 8867020

Extracellular Ca2+ changes during transmitter application in the leech central nervous system

Lohr C, Rose C, Deitmer J · Neuroscience letters

Added to ASH registry: 2026-03-18

Genomics & Proteomics1995PMID 8745160

Central and peripheral 5-HT receptors in the leech (Hirudo medicinalis) redefined.

Leake et al. · General pharmacology

Added to ASH registry: 2026-05-28

Salivary Pharmacology1995PMID 7626625

Core domain of hirudin from the leech Hirudinaria manillensis: chemical synthesis, purification, and characterization of a Trp3 analog of fragment 1-47.

De Filippis V et al. · Biochemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics1995PMID 7751442

Distribution and developmental expression of octopamine-immunoreactive neurons in the central nervous system of the leech

Gilchrist et al. · The Journal of comparative neurology

Added to ASH registry: 2026-05-28

Salivary Pharmacology1995PMID 8597538

High-level secretion of hirudin by Hansenula polymorpha--authentic processing of three different preprohirudins.

Weydemann U et al. · Applied microbiology and biotechnology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1995PMID 7643070

In situ hybridization reveals transient laminin B-chain expression by individual glial and muscle cells in embryonic leech central nervous system.

Luebke et al. · Journal of neurobiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1995PMID 7782716

Ingestive sensory inputs excite serotonin effector neurones and promote serotonin depletion from the leech central nervous system and periphery.

Groome et al. · The Journal of experimental biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1995PMID 7595161

Remodelling of an intact neurone in the central nervous system of the leech

Calabrese et al. · The Journal of experimental biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1995PMID 7673894

Repair of the central nervous system: lessons from lesions in leeches

von et al. · Journal of neurobiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1995PMID 8569452

Proteinase inhibitors from the European medicinal leech Hirudo medicinalis: structural, functional and biomedical aspects

Ascenzi P et al. · Molecular aspects of medicine

Added to ASH registry: 2026-03-18

Genomics & Proteomics1994PMID 8008832

Cellular and molecular approaches to neural repair in the medicinal leech

Blackshaw · Progress in neurobiology

Added to ASH registry: 2026-05-28

Salivary Pharmacology1994PMID 8001550

Probing the structure of hirudin from Hirudinaria manillensis by limited proteolysis. Isolation, characterization and thrombin-inhibitory properties of N-terminal fragments.

Vindigni A et al. · European journal of biochemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics1994PMID 8113785

Substrate-dependent interactions of leech microglial cells and neurons in culture

Masuda-Nakagawa et al. · Journal of neurobiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1994PMID 8112345

Isolation and characterization of hirustasin, an antistasin-type serine-proteinase inhibitor from the medical leech Hirudo medicinalis

Söllner C et al. · Eur J Biochem

Added to ASH registry: 2026-05-27

Drug Development1994PMID 8124815

Specific factor Xa inhibition reduces restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits

Ragosta M et al. · Circulation

Added to ASH registry: 2026-05-27

Genomics & Proteomics1993PMID 8099096

Bacteriological investigation of the occurrence and antibiotic sensitivities of the gut-flora of the potential southern African medicinal leech, Asiaticobdella buntonensis (Hirudinidae)

Wilken et al. · The Journal of hospital infection

Added to ASH registry: 2026-05-28

Salivary Pharmacology1993PMID 7685281

Novel hirudin variants from the leech Hirudinaria manillensis. Amino acid sequence, cDNA cloning and genomic organization.

Scacheri E et al. · European journal of biochemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics1993PMID 7504730

Selection of transmitter responses at sites of neurite contact during synapse formation between identified leech neurons.

Ching et al. · The Journal of physiology

Added to ASH registry: 2026-05-28

Salivary Pharmacology1993PMID 8376390

Structures of thrombin complexes with a designed and a natural exosite peptide inhibitor.

Qiu X et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics1993PMID 8493250

Studies on the host specificity of the medicinal blood leech Hirudo medicinalis L

Keim et al. · Parasitology research

Added to ASH registry: 2026-05-28

Genomics & Proteomics1993PMID 8397794

The complete amino acid sequence of a hirudin variant from the leech Hirudinaria manillensis

Electricwala A et al. · J Protein Chem

Added to ASH registry: 2026-05-27

Genomics & Proteomics1992PMID 1516742

Mesenchyme of embryonic reproductive ducts directs process outgrowth of Retzius neurons in the medicinal leech.

French et al. · Developmental biology

Added to ASH registry: 2026-05-28

Salivary Pharmacology1992PMID 1540584

Primary structure and function of novel O-glycosylated hirudins from the leech Hirudinaria manillensis.

Steiner V et al. · Biochemistry

Added to ASH registry: 2026-05-28

Drug Development1992PMID 1366111

[Hirudin--comeback of Hirudo medicinalis]

Lassila R · Duodecim; laaketieteellinen aikakauskirja

Added to ASH registry: 2026-03-18

Salivary Pharmacology1992PMID 1584585

Use of the medicinal leech in the treatment of ear diseases

Seleznev K et al. · ORL; journal for oto-rhino-laryngology and its related specialties

Added to ASH registry: 2026-03-18

Genomics & Proteomics1991PMID 1705969

Development of serotonin-induced ion currents in identified embryonic Retzius cells from the medicinal leech (Hirudo medicinalis).

Lessmann et al. · The Journal of neuroscience : the official journal of the Society for Neuroscience

Added to ASH registry: 2026-05-28

Salivary Pharmacology1991PMID 1773002

Isolation of thrombin inhibitor from the leech Hirudinaria manillensis.

Electricwala A et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis

Added to ASH registry: 2026-05-28

Salivary Pharmacology1991PMID 1773003

Structure-function relationships of the C-terminal functional domain of hirudin and its variants.

Krstenansky JL et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis

Added to ASH registry: 2026-05-28

Salivary Pharmacology1991PMID 1654318

The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity.

Liu LW et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics1991PMID 2046043

Two forms of sensitization of the local bending reflex of the medicinal leech.

Lockery et al. · Journal of comparative physiology. A, Sensory, neural, and behavioral physiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1991PMID 1821771

Expression and characterization of the N-terminal half of antistasin, an anticoagulant protein derived from the leech Haementeria officinalis

Palladino LO et al. · Protein Expr Purif

Added to ASH registry: 2026-05-27

Genomics & Proteomics1991PMID 1765068

Ornatins: potent glycoprotein IIb-IIIa antagonists and platelet aggregation inhibitors from the leech Placobdella ornata

Mazur P et al. · European journal of biochemistry

Added to ASH registry: 2026-05-27

Genomics & Proteomics1991PMID 1990979

Purification and characterization of recombinant antistasin: a leech-derived inhibitor of coagulation factor Xa

Nutt EM et al. · Arch Biochem Biophys

Added to ASH registry: 2026-05-27

Genomics & Proteomics1991PMID 1770166

Segmental differentiation in the leech central nervous system: proposed segmental homologs of the heart accessory neurons

Stewart RR et al. · Journal of Comparative Neurology

Added to ASH registry: 2026-05-27

Genomics & Proteomics1991PMID 2046044

Serotonin in the leech central nervous system: anatomical correlates and behavioral effects

Lent CM et al. · Journal of Comparative Physiology A

Added to ASH registry: 2026-05-27

Drug Development1991PMID 1771416

Isolation and characterization of hirudin from Hirudo medicinalis

Walsmann P · Seminars in thrombosis and hemostasis

Added to ASH registry: 2026-03-18

Drug Development1991PMID 1894194

The history of leeching and hirudin

Fields W · Haemostasis

Added to ASH registry: 2026-03-18

Clinical Trials1990PMID 2177589

[Hereditary deficiency of antithrombin III, protein C and protein S. A study of 31 patients from 8 unrelated families].

Lefrançois C et al. · Annales francaises d'anesthesie et de reanimation

Added to ASH registry: 2026-05-28

Genomics & Proteomics1990PMID 1979445

Accumulation of laminin and microglial cells at sites of injury and regeneration in the central nervous system of the leech

Masuda-Nakagawa et al. · Proceedings. Biological sciences

Added to ASH registry: 2026-05-28

Genomics & Proteomics1990PMID 2306252

Amino acid sequence of ghilanten: anticoagulant-antimetastatic principle of the South American leech, Haementeria ghilianii

Blankenship et al. · Biochemical and biophysical research communications

Added to ASH registry: 2026-05-28

Genomics & Proteomics1990PMID 1698836

Expression of surface glycoproteins early in leech neural development.

McGlade-McCulloh E et al. · The Journal of comparative neurology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1990PMID 2169963

Glutaminergic responses of neuropile glial cells and Retzius neurones in the leech central nervous system.

Dörner et al. · Brain research

Added to ASH registry: 2026-05-28

Salivary Pharmacology1990PMID 1690651

Preparation of monoclonal antibodies to hirudin and hirudin peptides. A method for studying the hirudin--thrombin interaction.

Schlaeppi JM et al. · European journal of biochemistry

Added to ASH registry: 2026-05-28

Salivary Pharmacology1990PMID 2266119

Production, properties, and thrombin inhibitory mechanism of hirudin amino-terminal core fragments.

Chang JY · The Journal of biological chemistry

Added to ASH registry: 2026-05-28

Salivary Pharmacology1990PMID 2380171

The COOH-terminal domain of hirudin. An exosite-directed competitive inhibitor of the action of alpha-thrombin on fibrinogen.

Naski MC et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-28

Clinical Trials1990PMID 2205717

[The medicinal leech Hirudo medicinalis: clinical use of the animal and therapeutic prospects of hirudin]

Henriot J et al. · Journal de pharmacie de Belgique

Added to ASH registry: 2026-03-18

Salivary Pharmacology1989PMID 2745433

Antistasin, an inhibitor of coagulation and metastasis, binds to sulfatide (Gal(3-SO4) beta 1-1Cer) and has a sequence homology with other proteins that bind sulfated glycoconjugates.

Holt GD et al. · The Journal of biological chemistry

Added to ASH registry: 2026-05-28

Salivary Pharmacology1989PMID 2620063

Contribution of the N-terminal region of hirudin to its interaction with thrombin.

Wallace A et al. · Biochemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics1989PMID 2809497

Serotonin differentially modulates two K+ currents in the Retzius cell of the leech.

Acosta-Urquidi et al. · The Journal of experimental biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1989PMID 2777803

Antistasin, a leech-derived inhibitor of factor Xa. Kinetic analysis of enzyme inhibition and identification of the reactive site

Dunwiddie C et al. · J Biol Chem

Added to ASH registry: 2026-05-27

Genomics & Proteomics1989PMID 2470652

Cloning and expression of cDNA encoding antistasin, a leech-derived protein having anti-coagulant and anti-metastatic properties

Han JH et al. · Gene

Added to ASH registry: 2026-05-27

Genomics & Proteomics1989PMID 2465376

Effects of cyclic nucleotides and calcium/calmodulin on protein phosphorylation in the CNS of Hirudo medicinalis

Garcia-Gil M et al. · Journal of neurochemistry

Added to ASH registry: 2026-05-26

Drug Development1989PMID 2688101

Production and evaluation of recombinant hirudin

Courtney M et al. · Seminars in thrombosis and hemostasis

Added to ASH registry: 2026-03-18

Genomics & Proteomics1988PMID 3267510

Segmentation in leech development.

Weisblat et al. · Development (Cambridge, England)

Added to ASH registry: 2026-05-28

Genomics & Proteomics1988PMID 3209972

Ingestive behaviour and physiology of the medicinal leech

Lent CM et al. · Journal of Experimental Biology

Added to ASH registry: 2026-05-27

Genomics & Proteomics1987PMID 3606298

Afferent sensillar inputs to the Retzius cell of the leech Hirudo medicinalis.

Carretta et al. · Archives italiennes de biologie

Added to ASH registry: 2026-05-28

Genomics & Proteomics1987PMID 3038045

Axonal projections of the Retzius cells to the dorsal segmental root in the leech Hirudo medicinalis.

Carretta et al. · Archives italiennes de biologie

Added to ASH registry: 2026-05-28

Genomics & Proteomics1987PMID 3323399

Neurite outgrowth and synapse formation by identified leech neurones in culture

Chiquet et al. · The Journal of experimental biology

Added to ASH registry: 2026-05-28

Salivary Pharmacology1987PMID 3578808

Rapid purification and revised amino-terminal sequence of hirudin: a specific thrombin inhibitor of the bloodsucking leech.

Mao SJ et al. · Analytical biochemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics1987PMID 3594242

Regeneration of afferent axons into discrete tracts within peripheral nerves in the leech.

Peinado A et al. · Brain research

Added to ASH registry: 2026-05-28

Genomics & Proteomics1987PMID 2821243

The regulation of intracellular pH by identified glial cells and neurones in the central nervous system of the leech.

Deitmer et al. · The Journal of physiology

Added to ASH registry: 2026-05-28

Clinical Trials1987PMID 2950042

Thrombosis in inherited deficiencies of antithrombin, protein C, and protein S.

Rosenberg RD et al. · Human pathology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1987PMID 3694111

On the termination of ingestive behaviour by the medicinal leech

Lent CM, Dickinson MH · Journal of Experimental Biology

Added to ASH registry: 2026-05-27

Genomics & Proteomics1986PMID 3023603

Initiation of swimming activity by trigger neurons in the leech subesophageal ganglion. II. Role of segmental swim-initiating interneurons.

Brodfuehrer et al. · Journal of comparative physiology. A, Sensory, neural, and behavioral physiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1986PMID 3723072

Swim initiation in the leech by serotonin-containing interneurones, cells 21 and 61.

Nusbaum et al. · The Journal of experimental biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1986PMID 3950699

Regeneration of a distinctive set of axosomatic contacts in the leech central nervous system

French KA, Muller KJ · The Journal of neuroscience : the official journal of the Society for Neuroscience

Added to ASH registry: 2026-05-26

Genomics & Proteomics1985PMID 2993546

Regeneration of axons and synaptic connections by touch sensory neurons in the leech central nervous system

Macagno et al. · The Journal of neuroscience : the official journal of the Society for Neuroscience

Added to ASH registry: 2026-05-28

Genomics & Proteomics1985PMID 3835843

Synaptic effects elicited in the Retzius cells of the leech Hirudo medicinalis by stimulation of the segmental roots.

Carretta et al. · Archives italiennes de biologie

Added to ASH registry: 2026-05-28

Genomics & Proteomics1985PMID 4027701

Serotonergic modulation of the feeding behavior of the medicinal leech

Lent CM · Brain Research Bulletin

Added to ASH registry: 2026-05-27

Genomics & Proteomics1984PMID 6329431

Serotonin and Retzius cell depress the hyperpolarization following impulses of leech touch cell.

Belardetti et al. · Brain research

Added to ASH registry: 2026-05-28

Genomics & Proteomics1983PMID 6317851

Accurate regeneration of an electrical synapse between two leech neurones after destruction of the ensheathing glial cell

Elliott et al. · The Journal of physiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1983PMID 6616194

Microglial movement to sites of nerve lesion in the leech CNS.

Morgese VJ et al. · Brain research

Added to ASH registry: 2026-05-28

Genomics & Proteomics1983PMID 6619920

Sprouting and regeneration of sensory axons after destruction of ensheathing glial cells in the leech central nervous system

Elliott et al. · The Journal of neuroscience : the official journal of the Society for Neuroscience

Added to ASH registry: 2026-05-28

Salivary Pharmacology1983PMID 6418572

The functional domain of hirudin, a thrombin-specific inhibitor.

Chang JY · FEBS letters

Added to ASH registry: 2026-05-28

Genomics & Proteomics1982PMID 6186389

Cell clones and segmentation in leech development.

Zackson · Cell

Added to ASH registry: 2026-05-28

Genomics & Proteomics1982PMID 6184342

Immunohistochemical demonstration of peptides, serotonin and dopamine-beta-hydroxylase-like material in the nervous system of the leech Hirudo medicinalis.

Osborne et al. · Histochemistry

Added to ASH registry: 2026-05-28

Genomics & Proteomics1981PMID 7023608

Long-term survival of glial segments during nerve regeneration in the leech

Elliot et al. · Brain research

Added to ASH registry: 2026-05-28

Genomics & Proteomics1981PMID 7320865

Membrane properties and selective connexions of identified leech neurones in culture

Fuchs et al. · The Journal of physiology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1981PMID 7229143

Regeneration of axons and nerve cell bodies in the CNS of annelids.

Hulsebosch CE et al. · The Journal of comparative neurology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1981PMID 7259396

Two bidirectional nerve cord systems converging with electrical and chemical synapses on the Retzius cells of the leech Hirudo Medicinalis.

Carretta et al. · Archives italiennes de biologie

Added to ASH registry: 2026-05-28

Genomics & Proteomics1980PMID 6161047

Synapse regeneration and signals for directed axonal growth in the central nervous system of the leech

Scott et al. · Developmental biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1980PMID 7032084

[Leeches: haementeria costata (Fr. Müller) and Hirudo medicinalis L. (Hirudinea) in the Kopań lake]

Hajduk D · Wiadomosci parazytologiczne

Added to ASH registry: 2026-03-18

Genomics & Proteomics1979PMID 482931

Correct axonal regeneration after target cell removal in the central nervous system of the leech

Muller et al. · Science (New York, N.Y.)

Added to ASH registry: 2026-05-28

Genomics & Proteomics1979PMID 383168

Synapses between neurones in the central nervous system of the leech

Muller · Biological reviews of the Cambridge Philosophical Society

Added to ASH registry: 2026-05-28

Genomics & Proteomics1978PMID 352244

Neural circuits for generating rhythmic movements

Friesen W, Stent G · Annual review of biophysics and bioengineering

Added to ASH registry: 2026-03-18

Genomics & Proteomics1977PMID 23544

Regeneration of synaptic connections by sensory neurons in leech ganglia maintained in culture

Wallace et al. · Proceedings of the Royal Society of London. Series B, Biological sciences

Added to ASH registry: 2026-05-28

Genomics & Proteomics1976PMID 181202

Modification and regeneration of synaptic connections in cultured leech ganglia

Miyazaki et al. · Cold Spring Harbor symposia on quantitative biology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1975PMID 162801

A multisomatic axon in the central nervous system of the leech

Frank et al. · The Journal of comparative neurology

Added to ASH registry: 2026-05-28

Genomics & Proteomics1972PMID 4501577

Regeneration and changes in synaptic connections between individual nerve cells in the central nervous system of the leech

Jansen et al. · Proceedings of the National Academy of Sciences of the United States of America

Added to ASH registry: 2026-05-28

Genomics & Proteomics1972PMID 4665284

The amine and amino acid composition in the Retzius cells of the leech Hirudo medicinalis.

Osborne et al. · Experientia

Added to ASH registry: 2026-05-28

Genomics & Proteomics1971PMID 4328425

Patterns of regeneration between individual nerve cells in the central nervous system of the leech

Baylor et al. · Nature

Added to ASH registry: 2026-05-28

Genomics & Proteomics1969PMID 4305885

Chemical and ultrastructural identification of 5-hydroxytryptamine in an identified neuron.

Rude et al. · The Journal of cell biology

Added to ASH registry: 2026-05-28

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