Publication Tracker \u2014 ASH
Live timeline of 10030 PMID-verified articles ASH tracks. Filter by category to explore the literature growth toward our 10,000-paper coverage goal.
This page is the public face of ASH's literature-tracking pipeline. Every entry here is parsed from PubMed metadata directly, cross-checked against the article's real PMID, and committed into the open-source registry behind this site. Hand-curated registries are tracked separately at PMID Audit Status.
The corpus grows continuously as new PubMed-indexed hirudotherapy and leech-derived-compound papers are published. The 10,000-article goal is the coverage threshold needed to consider ASH's literature surveillance comprehensive across all leech-related biomedical sub-fields.
10030
Total tracked articles
PMID-verified, auto-imported from PubMed
2007
Added in last 12 months
Rolling window ending 2026-05-27
100%
Progress toward 10,000-paper goal
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Showing 3256 articles in Drug Development. Clear filter
Timeline by publication year
2026
146 articlesCurrent yearComparison of aspirin and rivaroxaban for the prevention of pulmonary embolism and deep vein thrombosis in high thrombotic risk patients with systemic lupus erythematosus: study protocol for a multicentre, prospective, randomised controlled trial
Zhang et al. · Lupus science & medicine
Added to ASH registry: 2026-05-29
Dabigatran outperforms warfarin in elderly patients with atrial fibrillation and stable coronary artery disease: reduced risks of bleeding and cardiovascular events
Song et al. · American journal of translational research
Added to ASH registry: 2026-05-29
Dabigatran-induced acute hepatitis in a patient with atrial fibrillation: a rare case report
Hsu et al. · European heart journal. Case reports
Added to ASH registry: 2026-05-29
Edoxaban for stroke prevention in Chinese patients with atrial fibrillation: 1-year follow-up of the ETNA-AF-China study
Guo et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-29
Edoxaban for stroke prevention in patients with atrial fibrillation: Of randomized and real-world evidence
de · Indian pacing and electrophysiology journal
Added to ASH registry: 2026-05-29
Edoxaban-induced enterocolitis: The first case report demonstrating distinct endoscopic and histological features
Endo et al. · DEN open
Added to ASH registry: 2026-05-29
Efficacy and safety of reduced-dose versus full-dose DOACs in extended treatment of VTE: A systematic review and meta-analysis
Bilal et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-29
Efficacy of argatroban plus alteplase versus intravenous alteplase according to diabetes mellitus in acute ischemic stroke
Hou et al. · Scientific reports
Added to ASH registry: 2026-05-29
Extended Rivaroxaban Therapy for Cancer-Associated Low-Risk Pulmonary Embolism by Chemotherapy Status: Insights from the ONCO PE Trial
Xiong et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-29
Peak and Trough Concentration Ranges of Factor Xa Inhibitors for Preventing Thromboembolic Stroke in Korean Patients with Non-valvular Atrial Fibrillation
Park et al. · Annals of laboratory medicine
Added to ASH registry: 2026-05-29
Pharmacogenomic profiling of ABCB1 and CES1 in atrial fibrillation patients on dabigatran from a multiethnic Malaysian cohort
Tan et al. · Scientific reports
Added to ASH registry: 2026-05-29
Real-World Edoxaban Concentrations in Older Patients Receiving Reduced-Dose Regimens
Tang et al. · Clinical pharmacology and therapeutics
Added to ASH registry: 2026-05-29
Reversal of Progressive In-Hospital Posterior Artery-to-Artery Embolic Stroke With Argatroban: A Case Report
She et al. · British journal of hospital medicine (London, England : 2005)
Added to ASH registry: 2026-05-29
Total Clinical Event Burden with Edoxaban Monotherapy versus Dual Antithrombotic Therapy in Atrial Fibrillation and Stable Coronary Artery Disease: Insights from the EPIC-CAD Trial
Kim et al. · Journal of the American Heart Association
Added to ASH registry: 2026-05-29
A comprehensive multicenter study assessing the impact of abelacimab, asundexian and milvexian on coagulation assays
Goubeau et al. · Blood advances
Added to ASH registry: 2026-05-28
A heparin-functionalized scaffold loaded with pleiotrophin enhances endothelialization and angiogenic potential in liver tissue engineering
Yadav CJ et al. · Biomaterials science
Added to ASH registry: 2026-05-28
A Thorough QT Study to Assess the Effects of Milvexian on Cardiac Repolarization in Healthy Participants
Zannikos et al. · Clinical pharmacology in drug development
Added to ASH registry: 2026-05-28
Abelacimab vs Rivaroxaban in Older Individuals With Atrial Fibrillation: A Prespecified Analysis of the Phase 2b AZALEA-TIMI 71 Trial
Al et al. · JAMA cardiology
Added to ASH registry: 2026-05-28
Acute unintentional single-substance pediatric exposures to direct factor Xa inhibitors reported to US Poison Centers, 2011-2019
Kolbeck M et al. · Clinical toxicology (Philadelphia, Pa.)
Added to ASH registry: 2026-05-28
Advancing Point-of-Care Analysis: The Future of Thromboelastographic DOAC-Detection: A Systematic Review
Herpertz GU et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Andexanet alfa for the reversal of anticoagulation: Dutch practice data
Krommenhoek JF et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Apixaban Initiation in Hemodialysis Patients With Newly Diagnosed Atrial Fibrillation
Lu et al. · American journal of kidney diseases : the official journal of the National Kidney Foundation
Added to ASH registry: 2026-05-28
Association of Edoxaban Pharmacokinetics With Bleeding in Older Patients With Atrial Fibrillation Treated With Low-Dose Edoxaban: A Post Hoc Analysis of a Randomized Controlled Trial
Okumura K et al. · Journal of the American Heart Association
Added to ASH registry: 2026-05-28
Automated Thromboelastometry for Semiquantitative Assessment of High Heparin Concentrations: A Feasibility Study in Healthy Volunteers
Pada et al. · Health science reports
Added to ASH registry: 2026-05-28
Bioinspired apixaban nanosuspension-loaded polymeric microneedle arrays for non-invasive transdermal delivery: a skin-friendly patch
Abdel-Messih HA et al. · European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Added to ASH registry: 2026-05-28
Bleeding Risk with Apixaban vs. Rivaroxaban in Acute Venous Thromboembolism
Castellucci LA et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Cancer-Associated Stroke Complicated by Heparin-Induced Thrombocytopenia: A case report.
Okada T et al. · Internal medicine (Tokyo, Japan)
Added to ASH registry: 2026-05-28
Caught in Transit: Mobile Right Atrial Thrombus in Intermediate-High-Risk Pulmonary Embolism Treated With Half-Dose Alteplase
Gomaa et al. · The American journal of case reports
Added to ASH registry: 2026-05-28
Combined Antithrombin and Heparin Supplementation to Blood for Restoring Heparin Responsiveness After Andexanet Alfa Exposure: An In Vitro Model
Butt et al. · EJHaem
Added to ASH registry: 2026-05-28
Comparative efficacy and safety of apixaban and rivaroxaban versus warfarin in atrial fibrillation patients with end-stage renal disease: a systematic review and meta-analysis
Wu X et al. · Renal failure
Added to ASH registry: 2026-05-28
Comparing anti-platelet and anti-thrombin therapies in the ischaemia-reperfusion injured coronary microcirculation of healthy and diabetic mice
Mitchell et al. · Basic research in cardiology
Added to ASH registry: 2026-05-28
Comparing Hemostatic Efficacy of Four-Factor Prothrombin Complex Concentrate with Andexanet Alfa in an Apixaban-Treated Polytrauma Male Porcine Model
Grottke et al. · Anesthesiology
Added to ASH registry: 2026-05-28
Delayed-type hypersensitivity to low-molecular-weight heparin and cross-reactivity to fondaparinux and danaparoid in a twin pregnancy
House et al. · Obstetric medicine
Added to ASH registry: 2026-05-28
Design and rationale of aspirin versus aspirin and fondaparinux prior to early invasive strategy in patients with NSTEMI: The FOXY trial
Fur et al. · American heart journal
Added to ASH registry: 2026-05-28
Design and rationale of the GUARD-OAC: A randomized controlled trial evaluating proton pump inhibitor cotherapy for gastrointestinal protection in patients requiring direct oral anticoagulants
Ahn HJ et al. · American heart journal
Added to ASH registry: 2026-05-28
Design, synthesis and biological evaluation of novel FXIa inhibitors featuring five-membered heterocycles as P2' fragments
Wu et al. · European journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Development of an Oral Anticoagulation Strategy for Permanent Artificial Lung Support
Hong et al. · Transplantation
Added to ASH registry: 2026-05-28
Development of selective NBD-based fluorescent probes for in vitro detection of factor XIa and Thrombus imaging
Zhuang et al. · Bioorganic chemistry
Added to ASH registry: 2026-05-28
Direct Oral Anticoagulant Inhibitors: Mode of Action, Clinical Aspects
Hassan et al. · Handbook of experimental pharmacology
Added to ASH registry: 2026-05-28
Direct Oral Anticoagulants for Cancer-Associated Venous Thromboembolism in Hematologic Malignancies: A Comprehensive Review
Zhu Y et al. · European journal of haematology
Added to ASH registry: 2026-05-28
Direct Oral Anticoagulants for Portal Vein Thrombosis in Cirrhosis: From Pharmacology to Clinical Practice
Al Naamani KM et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Direct Oral Anticoagulants Versus Warfarin in Atrial Fibrillation With Advanced Chronic Kidney Disease: A Systematic Review and Meta-Analysis
Metwaly AS et al. · Cureus
Added to ASH registry: 2026-05-28
Discovery of the First Highly Potent, Selective, Irreversible Small-Molecule Factor XIIa Inhibitor for Treating Sepsis
Geng et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Dose-Response Efficacy and Safety of Factor XI/XIa Inhibitors in Atrial Fibrillation; a Systematic Review and Meta-Analysis With Subgroup Exploration and Trial Sequential Validation
Faizan et al. · Clinical cardiology
Added to ASH registry: 2026-05-28
Dose-Specific Intra-Arterial Thrombolysis After Endovascular Thrombectomy for Large-Vessel Occlusion Stroke: A Network Meta-Analysis of Randomized Trials
Frechiani et al. · Stroke (Hoboken, N.J.)
Added to ASH registry: 2026-05-28
Economic evaluation of direct oral anticoagulants (DOACs) for venous thromboembolism with different etiologies: a systematic review
Karimi F et al. · Health economics review
Added to ASH registry: 2026-05-28
Efficacy and Safety of Apixaban in Cancer-Associated Thromboembolism: A Narrative Review
Aperna F et al. · Cardiology in review
Added to ASH registry: 2026-05-28
Efficacy of combined atorvastatin and argatroban therapy in acute cerebral infarction
Xu et al. · Pakistan journal of pharmaceutical sciences
Added to ASH registry: 2026-05-28
Emergency reversal of Rivaroxaban with Andexanet alfa in a child with hemorrhagic brain metastasis from Wilms tumor
Rafaelian A et al. · Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Added to ASH registry: 2026-05-28
Eudragit S100-coated liposomes: a pH-responsive strategy to overcome dabigatran etexilate's oral bioavailability challenge
Elsayad et al. · The Journal of pharmacy and pharmacology
Added to ASH registry: 2026-05-28
Excessive Apixaban Concentrations in a Bleeding Patient Treated With Pharmacological Reversal and Extracorporal Removal-A Case Report
Kraus RF et al. · Pharmacology research & perspectives
Added to ASH registry: 2026-05-28
Expert Opinion on Implementing Oral Anticoagulation Reversal Protocols in US Hospitals
Berger et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Exploration of Mechanisms of Keliu Pill on the Inhibition of Lymphangiogenesis in Non-small Cell Lung Cancer Based on Network Pharmacology and Experimental Validation
Yang et al. · Applied biochemistry and biotechnology
Added to ASH registry: 2026-05-28
Factor XI Inhibitors in Atrial Fibrillation: Insights and Implications from Recent Trials
Falama RB et al. · Advances in therapy
Added to ASH registry: 2026-05-28
Factor XIa Inhibitors Versus Direct Oral Anticoagulants for Atrial Fibrillation: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Shahid et al. · Cardiovascular drugs and therapy
Added to ASH registry: 2026-05-28
Fixed dose versus 3-day loading dose warfarin initiation in atrial fibrillation: effects on INR stabilization and time in the therapeutic range
Syed et al. · International journal of clinical pharmacy
Added to ASH registry: 2026-05-28
Fondaparinux-associated thrombocytopenia as a cause of bilateral pulmonary embolism
Acebo et al. · Medicina clinica
Added to ASH registry: 2026-05-28
From Physiology to Clinical Practice in Pancreatic Cancer-Related Thromboembolism-A Review
Jarowicz M et al. · Cancers
Added to ASH registry: 2026-05-28
Impact of Atrial Fibrillation Pattern on Edoxaban Antithrombotic Therapy in Patients With Atrial Fibrillation and Stable Coronary Artery Disease: A Secondary Analysis of the EPIC-CAD Randomized Clinical Trial
Yu et al. · Journal of the American Heart Association
Added to ASH registry: 2026-05-28
Impact of renal function on edoxaban antithrombotic therapy in patients with atrial fibrillation and stable coronary artery disease: a prespecified analysis of the EPIC-CAD trial
Lee et al. · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Added to ASH registry: 2026-05-28
Increased Prophylactic Enoxaparin Dosing Is Associated With Improved Achievement of Target anti-Xa Levels; Implementation of the Western Trauma Association Venous-Thromboembolism Guidelines
McKinzie et al. · The Journal of surgical research
Added to ASH registry: 2026-05-28
Individualized antithrombotic therapy in acute coronary syndrome: The role of thrombin pathway inhibition and aspirin.
Tantry et al. · Kardiologia polska
Added to ASH registry: 2026-05-28
Interference in protein S activity testing and free protein S: impact of lupus anticoagulant, elevated factor VIII, and anticoagulants
Yan J et al. · Clinica chimica acta; international journal of clinical chemistry
Added to ASH registry: 2026-05-28
Laboratory Testing of Direct Oral Anticoagulants
Reilly-Stitt · Handbook of experimental pharmacology
Added to ASH registry: 2026-05-28
Laminin G domains define a critical interface for protein S-mediated factor IXa inhibition
Yasmin R et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Markers for platelet function testing by flow cytometry: where are we now? A clinical perspective.
Spurgeon · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Measurement of Active Thrombin Bound to Circulating D-Dimers as a Sensitive Biomarker for Prothrombotic Conditions
Stikarova J et al. · Journal of clinical laboratory analysis
Added to ASH registry: 2026-05-28
Mechanistic prediction of apixaban and rivaroxaban secretion into human milk and infant systemic exposure through an integrated physiologically based pharmacokinetic framework
Yi B et al. · Drug metabolism and disposition: the biological fate of chemicals
Added to ASH registry: 2026-05-28
Naringin binds and activates protein C inhibitor for enhanced inhibition of thrombin and activated protein C with implications in coagulation control
Siddiqui U et al. · Journal of biomolecular structure & dynamics
Added to ASH registry: 2026-05-28
Non-ST-segment elevation acute coronary syndrome: understanding the full spectrum to guide management.
Savonitto et al. · European heart journal
Added to ASH registry: 2026-05-28
Off-label underdosing of edoxaban antithrombotic therapy for patients with atrial fibrillation and stable coronary artery disease: findings from the EPIC-CAD trial
Cho et al. · Heart (British Cardiac Society)
Added to ASH registry: 2026-05-28
Optimising protamine dosing for heparin reversal after cardiopulmonary bypass: a population pharmacokinetic-pharmacodynamic study
Lanoiselée et al. · British journal of anaesthesia
Added to ASH registry: 2026-05-28
Perioperative Management of Immune Thrombocytopenic Purpura in Cardiac Surgery: A Systematic Review of the Literature in Urgent and Elective Settings
Said K et al. · Cureus
Added to ASH registry: 2026-05-28
Perioperative Transfusion Requirements in Pediatric Patients Receiving Apixaban Prior to Cardiac Surgery With Cardiopulmonary Bypass
Longacre et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-28
Pharmacologic Factor XI/XIa Inhibitors: What the Laboratory Hematologist Needs to Know
Weitz et al. · Clinics in laboratory medicine
Added to ASH registry: 2026-05-28
PK/PD interactions of antiarrhythmic drugs and oral anticoagulants in atrial fibrillation patients: clinical implications for stroke and dementia prevention
Oh et al. · Toxicological research
Added to ASH registry: 2026-05-28
Postoperative reduction in thrombin generation induced by elevated levels of tissue factor pathway inhibitor in cardiac surgery: a prospective observational study
Kitajo et al. · Journal of anesthesia
Added to ASH registry: 2026-05-28
Prevalence of Potentially Inappropriate Apixaban Prescribing Within a Single-Centre Tertiary Hospital
Creeper et al. · Australasian journal on ageing
Added to ASH registry: 2026-05-28
Prothrombin complex concentrate for reversal of factor Xa inhibitor-associated acute major gastrointestinal bleeding
Shamiea M et al. · The American journal of medicine
Added to ASH registry: 2026-05-28
Quality Assurance in Platelet Function Testing.
Smock et al. · Clinics in laboratory medicine
Added to ASH registry: 2026-05-28
Quantitative Model-Informed Dose Selection for a Milvexian Phase III Study in Patients With Atrial Fibrillation
Zhou et al. · Clinical pharmacology and therapeutics
Added to ASH registry: 2026-05-28
Randomized trial of low-dose, ultrasound-assisted thrombolysis or heparin for pulmonary embolism.
Kjaergaard J et al. · Cardiovascular research
Added to ASH registry: 2026-05-28
Rational design of heparin antagonist: Guanidine-based mimetics unveil key carbohydrate-carbohydrate interactions
Chandra et al. · European journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Rationale for the milvexian dosing in the phase 3 LIBREXIA program
Weitz et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Real-Time Individualization of UFH Dosing in Cardiac Procedures: Development and Validation of an Online ACT-Based Target-Controlled Tool
Ollier et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-28
Recent advances in factor XII(a) inhibitors: an updated patent landscape (2020-present)
Kalinin et al. · Expert opinion on therapeutic patents
Added to ASH registry: 2026-05-28
Relevance and limitations of clinical follow-up in a pharmacokinetic study on direct oral anticoagulants
Terrier et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-28
Reperfusion thrombolytic therapy for ischemic stroke in patients on non-vitamin K antagonist oral anticoagulants: study protocol of a phase II randomized clinical trial
Karaszewski B et al. · Trials
Added to ASH registry: 2026-05-28
Retrospective modeling study of ChatGPT (GPT 4) warfarin dose adjustment in patients with INRs outside the therapeutic range
Tezcan et al. · Digital health
Added to ASH registry: 2026-05-28
Reusing Blood Samples from a Hospital-based Cohort to Apixaban Plasma Concentrations
Murray et al. · medRxiv : the preprint server for health sciences
Added to ASH registry: 2026-05-28
Role of Concentration in Opposing Effects of Anandamide on Nociceptive Synapses versus Non-nociceptive Synapses
Burrell BD · eNeuro
Added to ASH registry: 2026-05-28
Safety and efficacy of direct oral anticoagulants in pediatric oncology patients: real-world data from two quaternary care pediatric centers
Kumar R et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Safety of Prothrombin Complex Concentrate for Emergency Surgery According to the Oral Factor Xa Inhibitor Level
Eshaghpour A et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Simplifying the next-generation of anticoagulants: Elexians - Why a unified nomenclature for FXI/XIa inhibitors is needed
Kholmukhamedov et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Single-domain antibodies to reverse the effects of factor Xa inhibitors on coagulation tests
Zhao J et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Systematic review on the design and methodology of the pediatric direct oral anticoagulant clinical trials for thrombosis prevention: communication from the ISTH SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis
Whitworth H et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Targeting Factor XI for Safer Anticoagulation: Emerging Data and Future Directions
Campanella F et al. · American journal of cardiovascular drugs : drugs, devices, and other interventions
Added to ASH registry: 2026-05-28
The Advances in Novel Delivery Strategies for Hirudin Against Cardiovascular Diseases
Li M et al. · Pharmaceuticals (Basel, Switzerland)
Added to ASH registry: 2026-05-28
The impact of body composition variability on coagulation monitoring in patients on direct oral factor Xa inhibitors for treatment of venous thromboembolism
Kurzmann-Guetl et al. · Frontiers in cardiovascular medicine
Added to ASH registry: 2026-05-28
The in vitro anticoagulant effect of milvexian in healthy neonates and children
Letunica et al. · Thrombosis research
Added to ASH registry: 2026-05-28
The ocular surface in type 2 diabetes: pathophysiology and impact of anti-diabetic drugs
Singh et al. · Progress in retinal and eye research
Added to ASH registry: 2026-05-28
The Risk for Bleeding in Patients With Atrial Fibrillation From Concomitant Use of Apixaban or Rivaroxaban With Diltiazem Compared With Metoprolol
Dawwas GK et al. · Annals of internal medicine
Added to ASH registry: 2026-05-28
Thrombosis Across Female-Specific Malignancies: From Chemotherapy-Driven Risk to Prophylaxis and Drug Interactions
Aghakouchakzadeh M et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Trends in Antithrombotic Therapy Initiation Among Patients With Stroke Pre- and Post-COVID-19 in Sweden-An Interrupted Time Series Study
Mousa et al. · Basic & clinical pharmacology & toxicology
Added to ASH registry: 2026-05-28
Use of Apixaban for Venous Thromboembolism Prophylaxis in an Older Hemodialysis Patient After Total Knee Replacement: A Case Report
Alanizi AH et al. · The American journal of case reports
Added to ASH registry: 2026-05-28
Venous thromboembolism prevention and treatment with factor XI/XIa inhibitors: current status and future perspectives
Del et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Venous thromboembolism prophylaxis in the intensive care unit: Is there a future role for factor XI/XIa inhibitors as novel antithrombotic agents?
Porres-Aguilar et al. · Medicina intensiva
Added to ASH registry: 2026-05-28
Weight based dosing of prophylactic enoxaparin was not associated with reduced venous thromboembolism events following open reduction and internal fixation of acetabular fractures
Nian et al. · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Added to ASH registry: 2026-05-28
A network pharmacology-based study on the mechanism of hirudin attenuates renal interstitial fibrosis through Nrf2 and NF-κB signalling pathways
Yang K et al. · Naunyn-Schmiedeberg's archives of pharmacology
Added to ASH registry: 2026-05-27
Alternate and Emerging Anticoagulation Strategies for Extracorporeal Membrane Oxygenation: A Scoping Review
Kumar A et al. · Journal of Clinical Medicine
Added to ASH registry: 2026-05-27
Alternate and Emerging Anticoagulation Strategies for Extracorporeal Membrane Oxygenation: A Scoping Review
Kumar AP et al. · Journal of clinical medicine
Added to ASH registry: 2026-05-27
Alternative anticoagulants in heparin-sensitive patients undergoing carotid artery interventions: A scoping review
Dmitriev AP et al. · Journal of vascular surgery
Added to ASH registry: 2026-05-27
An Overview of Anticoagulant Drugs Pharmacology, Therapeutic Approaches, Limitations and Perspectives
Morgovan C et al. · Pharmaceutics
Added to ASH registry: 2026-05-27
Anticoagulant peptide LR from Whitmania pigra ameliorates cerebral ischemia-reperfusion injury
Liu R et al. · Brain research
Added to ASH registry: 2026-05-27
Anticoagulant peptide LR from Whitmania pigra ameliorates cerebral ischemia-reperfusion injury
Liu R et al. · Brain Research
Added to ASH registry: 2026-05-27
Anticoagulation management and monitoring in ECMO: an international survey from the ISTH SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis
Regling K et al. · Research and Practice in Thrombosis and Haemostasis
Added to ASH registry: 2026-05-27
Argatroban Anticoagulation for Heparin Induced Thrombocytopenia After Heartmate 3 Implantation: A Case Series
Palacios-Castello C et al. · Transplantation Proceedings
Added to ASH registry: 2026-05-27
Commensal-myeloid crosstalk in neonatal skin regulates interleukin-1 signaling and cutaneous type 17 inflammation
Dhariwala MO et al. · Immunity
Added to ASH registry: 2026-05-27
Construction of Corynebacterium glutamicum for efficient secretion and production of recombinant proteins using the technology of ARTP mutagenesis and fluorescen activated droplet microfluidic screening
Liu X et al. · Bioresource technology
Added to ASH registry: 2026-05-27
Current use and limitations of direct thrombin inhibitors in pediatric ECMO: A European survey
Gardeton P et al. · Perfusion
Added to ASH registry: 2026-05-27
Current use and limitations of direct thrombin inhibitors in pediatric ECMO: A European survey
Gardeton T et al. · Perfusion
Added to ASH registry: 2026-05-27
Delayed-onset, persisting autoimmune heparin-induced thrombocytopenia with thrombosis following craniofacial surgery
Will VJ et al. · BMJ Case Reports
Added to ASH registry: 2026-05-27
Dilute Thrombin Time to Monitor Bivalirudin in Pediatric Extracorporeal Membrane Oxygenation — Progress Does Not Always Have to Cost More
Niebler RA · Pediatric Critical Care Medicine
Added to ASH registry: 2026-05-27
Duplication of the Antistasin-Like Structure Resulted in a New Anticoagulant Protein in the Medicinal Leech
Brovina KA et al. · Biomolecules
Added to ASH registry: 2026-05-27
Elucidating the neuroinflammatory modulatory mechanisms of Maixuekang capsule via network pharmacology and proteomics
Han et al. · Developmental neurobiology
Added to ASH registry: 2026-05-27
Elucidating the Neuroinflammatory Modulatory Mechanisms of Maixuekang Capsule via Network Pharmacology in Cerebral Ischemia/Reperfusion Injury Rats
Han H et al. · Developmental Neurobiology
Added to ASH registry: 2026-05-27
Evaluation of bivalirudin-based anticoagulation for extracorporeal membrane oxygenation, including patients with COVID-19
Raguindin M et al. · The journal of extra-corporeal technology
Added to ASH registry: 2026-05-27
Gene Expression Underlying Teloblast Formation in Leech (Annelida: Hirudinae)
Hsiao S et al. · Evolutionary bioinformatics online
Added to ASH registry: 2026-05-27
Genetically Encoded Multivalent Elastin-Like Polypeptide-Haemadin Fusion Proteins for Prolonged Antithrombotic Protection
Yang H et al. · Biomacromolecules
Added to ASH registry: 2026-05-27
Heparin-induced Thrombocytopenia During Multiple Extracorporeal Mechanical Support for Fulminant Myocarditis: A Case Report with a Literature Review
Morita Y et al. · Internal Medicine (Tokyo)
Added to ASH registry: 2026-05-27
Hirudin ameliorates kidney injury in DKD mice by decreasing SOD2 β-hydroxybutyrylation mediated ROS level and NLRP3 inflammasome formation
Li Y et al. · FASEB journal
Added to ASH registry: 2026-05-27
Identification and characterization of WpDestabilase, a novel destabilase from the salivary glands of Whitmania pigra
Huang B et al. · Protein expression and purification
Added to ASH registry: 2026-05-27
Impact of heparin-to-bivalirudin bridging time on hospitalization and safety outcomes in PCI for acute coronary syndrome
Wang G et al. · Frontiers in cardiovascular medicine
Added to ASH registry: 2026-05-27
Molecular Insights into Leech-Derived Bioactive Compounds: Biochemical Mechanisms and Therapeutic Potential
Raghavi S et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-27
Multicenter Registry Analysis of Bivalirudin for Primary Anticoagulation in Pediatric HeartMate 3 Recipients: ACTION Analysis
Lynch A et al. · ASAIO Journal
Added to ASH registry: 2026-05-27
Nitric oxide in the ECMO circuit as a treatment option for heparin-induced thrombocytopenia: A case report
Joelsons D et al. · Perfusion
Added to ASH registry: 2026-05-27
Postprocedural anticoagulation after primary percutaneous coronary intervention: 1-year results
Yan et al. · JACC. Asia
Added to ASH registry: 2026-05-27
Recombinant Fusion Protein Composed of Hirudin and Annexin A5 Shows Anti-Coagulant Activity In Vitro
Dong H et al. · Applied biochemistry and biotechnology
Added to ASH registry: 2026-05-27
Resolving Bivalirudin Interference on Fibrinogen Testing by the Use of Activated Carbon
Du J et al. · Journal of clinical laboratory analysis
Added to ASH registry: 2026-05-27
The great diversity: monomeric and oligomeric hirudins, hirudin-like factors and decorsins in the Asian medicinal leeches Hirudo nipponia and Hirudo tianjinensis
Kalatehjari P et al. · Parasitology research
Added to ASH registry: 2026-05-27
Thromboembolism related to heparin-induced thrombocytopenia during Impella support after cardiac surgery for free wall rupture: a case report
Aratame A et al. · AME Case Reports
Added to ASH registry: 2026-05-27
Traditional Chinese medicine in the treatment of diabetic kidney disease: the mechanisms of signaling pathways regulations
Li W et al. · Frontiers in endocrinology
Added to ASH registry: 2026-05-27
Updates on Use and Monitoring of Direct Thrombin Inhibitors
Navaei A et al. · Clinics in laboratory medicine
Added to ASH registry: 2026-05-27
Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT)-like Syndrome: A Case Report and Some Considerations on a Novel Diagnostic and Therapeutic Challenge
Delfino L et al. · Diagnostics
Added to ASH registry: 2026-05-27
Molecular Insights into Leech-Derived Bioactive Compounds: Biochemical Mechanisms and Therapeutic Potential
Raghavi S, Deva Darshini B, Saravanan KM, Anbarasu K · International journal of molecular sciences
Added to ASH registry: 2026-05-26
Effects of hirudotherapy on liver functions, lipid profile, and insulin sensitivity in rats with metabolic syndrome
Bilden A et al. · BMC complementary medicine and therapies
Added to ASH registry: 2026-03-18
2025
306 articlesA Cost-Effectiveness Analysis of Rivaroxaban Compared to Warfarin for the Management of Venous Thromboembolism in Western Kenya
O'Neill et al. · Clinical drug investigation
Added to ASH registry: 2026-05-29
Administration of decapsulated dabigatran via nasogastric tube: A case report
Kaneta et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-29
Analysis of hemorrhagic transformation and intracerebral hemorrhage under combination therapy with alteplase and antiplatelets or anticoagulants, using the Japanese Adverse Drug Event Report database
Nakai et al. · PloS one
Added to ASH registry: 2026-05-29
Argatroban plus alteplase in posterior versus anterior circulation stroke
Cui et al. · Annals of clinical and translational neurology
Added to ASH registry: 2026-05-29
Argatroban plus dual antiplatelet therapy versus dual antiplatelet alone for acute atherothrombotic cerebral infarction
Nakashima et al. · International journal of stroke : official journal of the International Stroke Society
Added to ASH registry: 2026-05-29
Association Between Argatroban and Outcomes of Branch Atheromatous Disease: A Propensity-Matched Analysis From MRI-Based Study
Li et al. · CNS neuroscience & therapeutics
Added to ASH registry: 2026-05-29
Association of Genetic Variants With Rivaroxaban Pharmacokinetics and Pharmacodynamics and Hemorrhage Risk Factors in Patients With Venous Thromboembolism
Li et al. · Journal of the American Heart Association
Added to ASH registry: 2026-05-29
Biological Variation of Hemostasis Analytes in Atrial Fibrillation Patients Using Dabigatran
Tilly et al. · The journal of applied laboratory medicine
Added to ASH registry: 2026-05-29
Bleeding risk among cancer patients receiving concurrent CYP-interacting tyrosine kinase inhibitors with direct oral anticoagulants versus alternative anticoagulation therapies
Tan et al. · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
Added to ASH registry: 2026-05-29
Bleeding Risk in the Early Postoperative Period after Atrial Fibrillation Ablation with Anticoagulant Therapy Using Dabigatran Etexilate
Takashima et al. · Biological & pharmaceutical bulletin
Added to ASH registry: 2026-05-29
Cost-effectiveness of apixaban in non-valvular atrial fibrillation (NVAF) based on effectiveness data from a Spanish study in clinical practice (real-world evidence)
Anguita et al. · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-29
Dabigatran Attenuates the Binding of Thrombin to Platelets-A Novel Mechanism of Action
Lindahl et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-29
Does direct oral anticoagulant lead-in dosing following initial parenteral therapy affect clinical outcomes in acute venous thromboembolism?: A retrospective cohort study
Kim et al. · International journal of clinical pharmacy
Added to ASH registry: 2026-05-29
Drug-drug interactions between epidermal growth factor receptor tyrosine kinase inhibitors and rivaroxaban in vitro and in vivo
Wang et al. · PloS one
Added to ASH registry: 2026-05-29
Edoxaban Monotherapy and Incidence of Transcatheter Heart Valve Leaflet Thrombosis - The Rotterdam Edoxaban (REDOX) Study
Adrichem et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-29
Effect of Argatroban Plus Dual Antiplatelet in Branch Atherosclerosis Disease: A Randomized Clinical Trial
Xu et al. · Stroke
Added to ASH registry: 2026-05-29
Effectiveness and Safety of Dose-Specific DOACs in Patients With Atrial Fibrillation: A Systematic Review and Network Meta-Analysis
Oh et al. · Cardiovascular therapeutics
Added to ASH registry: 2026-05-29
Effectiveness and Safety of Edoxaban in the Routine Clinical Care of Atrial Fibrillation Patients in Brazil: Prospective 1-Year Follow-Up Study - EdoBRA
Precoma et al. · Arquivos brasileiros de cardiologia
Added to ASH registry: 2026-05-29
Effectiveness and safety of rivaroxaban in patients with atrial fibrillation and heart failure in clinical practice: an indirect comparison of national and international registries
Cepeda et al. · Frontiers in cardiovascular medicine
Added to ASH registry: 2026-05-29
Effects of Argatroban on Hcy, hs-CRP and FIB levels in patients with acute cerebral infarction
Yang et al. · The International journal of neuroscience
Added to ASH registry: 2026-05-29
Efficacy and safety of reduced-dose versus full-dose direct oral anticoagulants for extended treatment of venous thromboembolism: A meta-analysis with trial sequential analysis and reconstructed time-to-event data
Ibrahim et al. · Thrombosis research
Added to ASH registry: 2026-05-29
Efficacy of antiplatelet drugs combined with Argatroban in treating acute ischemic stroke and its impact on patients' coagulation function and neurological function: a preliminary trial
Sun et al. · The International journal of neuroscience
Added to ASH registry: 2026-05-29
Evaluation of extended direct oral anticoagulant dosing strategies in patients with and without cancer from a prospective observational registry
Vlazny et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-29
Impact of Factor Xa inhibitors on cardiovascular events in older patients with nonvalvular atrial fibrillation
Takahashi et al. · Aging
Added to ASH registry: 2026-05-29
Impact of weight/BMI on clinical and bleeding events in 26 805 atrial fibrillation patients on edoxaban from the Global ETNA-AF Registry
Boriani et al. · European journal of preventive cardiology
Added to ASH registry: 2026-05-29
In vivo Pharmacokinetic Interactions Between Palbociclib and Rivaroxaban or Apixaban: Implications for Increased Drug Exposure and Dose Adjustments
Du et al. · Drug design, development and therapy
Added to ASH registry: 2026-05-29
In Vivo pharmacokinetic interactions of ribociclib with rivaroxaban and apixaban in rats: implications for increased drug exposure and dose adjustments
Liu et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-29
Laboratory Measurement of Rivaroxaban in Patient with Cancer-Associated Thromboembolism; Focus on Initial Rivaroxaban Therapy
Yoon et al. · Clinical laboratory
Added to ASH registry: 2026-05-29
Literature-based case analysis of serious adverse drug events associated with edoxaban
Luan et al. · European journal of clinical pharmacology
Added to ASH registry: 2026-05-29
Low-dose direct oral anticoagulants for secondary prevention in patients at high risk for recurrence due to history of recurrent venous thromboembolic events or severe thrombophilia: a retrospective analysis of the Italian Survey on anTicoagulated pAtients RegisTry 2
Poli et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-29
Outcomes of Different Regimens of Rivaroxaban and Aspirin in Cardiovascular Diseases: A Network Meta-Analysis
Al-Salihi et al. · Journal of clinical medicine
Added to ASH registry: 2026-05-29
Plasma Concentrations of Direct Oral Anticoagulants in Patients with Nonvalvular Atrial Fibrillation and Different Degrees of Obesity
Menichelli et al. · Clinical pharmacokinetics
Added to ASH registry: 2026-05-29
Population pharmacokinetics of edoxaban in geriatric patients with atrial fibrillation
Edwina et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-29
Rivaroxaban for Venous Thromboembolism (VTE) in Paediatric Patients: An institutional retrospective observational study from the Low/Middle Income setting in Pakistan
Mahmood et al. · JPMA. The Journal of the Pakistan Medical Association
Added to ASH registry: 2026-05-29
Rivaroxaban Treatment in Pediatric Patients With Hematologic Malignancies and Venous Thromboembolism: A Report of Four Cases
Fukunaga et al. · Cureus
Added to ASH registry: 2026-05-29
Rivaroxaban versus low-molecular-weight heparins for short- and long-term prognosis in patients with deep vein thrombosis after spontaneous intracranial hemorrhage
Li et al. · Journal of comparative effectiveness research
Added to ASH registry: 2026-05-29
Rivaroxaban vs. enoxaparin for preventing venous thromboembolism after hip fracture operations: a retrospective cohort study
Zheng et al. · Frontiers in surgery
Added to ASH registry: 2026-05-29
Safety and efficacy of argatroban combined with antiplatelet therapy for acute mild-to-moderate ischemic stroke with large artery atherosclerosis
Yan et al. · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Added to ASH registry: 2026-05-29
Screening thrombin inhibitors from Yangxinshi tablets by online capillary electrophoresis-based immobilized enzyme microreactor and molecular docking
Liu et al. · Phytochemical analysis : PCA
Added to ASH registry: 2026-05-29
Site-Specific Antithrombotic Therapy: 24-Month Outcomes of the Randomized DESyne BDS Plus Trial Using a Novel Triple-Drug Eluting Coronary Implant With Two Anticoagulants and Sirolimus
Verheye et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-29
Three Year Follow-Up of Reduced Dose of Direct Oral Anticoagulants for Extended Treatment of Venous Thromboembolism: An Ambispective Cohort Study
Valeriani et al. · Diagnostics (Basel, Switzerland)
Added to ASH registry: 2026-05-29
Timely Initiation of Argatroban Improves Prognosis in Patients With Acute Ischemic Stroke Attributed to Large Artery Atherosclerosis: A Cohort Study
Liu et al. · Brain and behavior
Added to ASH registry: 2026-05-29
Treatment of portal vein thrombosis with rivaroxaban in an American cocker spaniel with chronic hepatitis: a case report
Niijima et al. · The Journal of veterinary medical science
Added to ASH registry: 2026-05-29
Two-year clinical outcomes of Taiwanese and other Asian ethnicities with atrial fibrillation treated with edoxaban in the ETNA-AF Asia registry
Wang et al. · Journal of arrhythmia
Added to ASH registry: 2026-05-29
Two-Year Follow-Up of Patients With Atrial Fibrillation Receiving Edoxaban in Routine Clinical Practice: Results From the Global ETNA-AF Program
De et al. · Clinical cardiology
Added to ASH registry: 2026-05-29
US cost-effectiveness analysis of apixaban compared with warfarin, dabigatran and rivaroxaban for nonvalvular atrial fibrillation, focusing on equal value of life years and health years in total
Atreja et al. · Journal of comparative effectiveness research
Added to ASH registry: 2026-05-29
Usual On-therapy Ranges of Drug Concentrations in Patients with Atrial Fibrillation Treated with Direct Oral Anticoagulants: A Systematic Review and Meta-analysis
de et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-29
Variability of Argatroban Effects on the Multiple APTT Reagents in High and Low Coagulation Activity Samples
Kumano et al. · International journal of laboratory hematology
Added to ASH registry: 2026-05-29
2025 ESVM Guidelines on interventional treatment of venous thromboembolism.
Schlager O et al. · VASA. Zeitschrift fur Gefasskrankheiten
Added to ASH registry: 2026-05-28
A novel bacteriophage pAEh1 for controlling Aeromonas hydrophila infection in aquaculture.
Jiang S et al. · Fish & shellfish immunology
Added to ASH registry: 2026-05-28
A Phase 1 Study to Assess the Effect of Fruquintinib on the Pharmacokinetics of P-gp and BCRP Substrates in Healthy Subjects
Gonzalez et al. · Clinical and translational science
Added to ASH registry: 2026-05-28
A Single-Domain VNAR Nanobody Binds with High-Affinity and Selectivity to the Heparin Pentasaccharide Fondaparinux
Gschwandtner et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-28
A UK-wide analysis of 2265 patients receiving a reversal agent for direct oral anticoagulant-associated bleeding.
? et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Abelacimab Has Fewer Bleeds Than Rivaroxaban, But Study Has Several Important Biases
Ebell. · American family physician
Added to ASH registry: 2026-05-28
Abelacimab versus Rivaroxaban in Patients with Atrial Fibrillation
Ruff et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Abelacimab versus Rivaroxaban in Patients with Atrial Fibrillation
Henry. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Abelacimab versus Rivaroxaban in Patients with Atrial Fibrillation
Raschi et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Abelacimab Versus Rivaroxaban in Patients With Atrial Fibrillation on Antiplatelet Therapy: A Prespecified Analysis of the AZALEA-TIMI 71 Trial
Al et al. · Circulation
Added to ASH registry: 2026-05-28
Abelacimab Versus Rivaroxaban in Patients With Atrial Fibrillation Receiving Oral Antiplatelet Therapy: Definitely Safe, but How Effective?
Steg et al. · Circulation
Added to ASH registry: 2026-05-28
Abelacimab versus rivaroxaban in patients with atrial fibrillation: Insights into the AZALEA-TIMI 71 study
Kattamuri et al. · Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion
Added to ASH registry: 2026-05-28
Abelacimab versus Rivaroxaban in Patients with Atrial Fibrillation. Reply
Ruff et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Alternative Anticoagulation for Patients with Heparin-Induced Thrombocytopenia on ECMO: A Narrative Review
Unic-Stojanovic D et al. · Biomedicines
Added to ASH registry: 2026-05-28
American Society of Hematology/International Society on Thrombosis and Haemostasis 2024 updated guidelines for treatment of venous thromboembolism in pediatric patients.
Monagle et al. · Blood advances
Added to ASH registry: 2026-05-28
An External Control Arm for the Oral Factor XIa Inhibitor Asundexian Phase 2 Trial in Atrial Fibrillation (PACIFIC-AF) Using Electronic Health Records
Vaitsiakhovich et al. · Cardiology and therapy
Added to ASH registry: 2026-05-28
Andexanet Alfa in Emergency Cranial Neurosurgical Procedures: A Bicentric Analysis of Efficacy and Safety
Hounchonou HF et al. · Neurocritical care
Added to ASH registry: 2026-05-28
Andexanet Alfa in Urgent Cardiac Surgery: A Case Report of Edoxaban Reversal for Acute Hemopericardium.
Al Mawed M et al. · The American journal of case reports
Added to ASH registry: 2026-05-28
Andexanet alfa-induced heparin resistance during percutaneous coronary intervention for ST-elevation myocardial infarction: a case report
Sasaki S et al. · European heart journal. Case reports
Added to ASH registry: 2026-05-28
Anticoagulant and anti-inflammatory effects of fondaparinux sodium during anterior cruciate ligament reconstruction in high risk VTE patients: A randomised controlled, triple blinded, prospective study
Zheng et al. · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Added to ASH registry: 2026-05-28
Anticoagulant drugs targeting factor XI/XIa and coagulation tests: we urgently need reliable pharmacodynamic data
Gouin-Thibault et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Anticoagulation during Extracorporeal Membrane Oxygenation (ECMO): A Selective Inhibitor of Activated Factor XII Compared to Heparin in an Ex Vivo Model
Gandini et al. · ACS pharmacology & translational science
Added to ASH registry: 2026-05-28
Anticoagulation in Atrial Fibrillation: Is a Paradigm Shift From Xa to XIa Inhibitors on the Horizon?
Zaman. · Cardiology in review
Added to ASH registry: 2026-05-28
Anticoagulation management and poor clinical outcomes in tamariki and rangatahi with rheumatic heart disease following mechanical valve replacement surgery in Counties Manukau.
Tangirala et al. · The New Zealand medical journal
Added to ASH registry: 2026-05-28
Anticoagulation Management During ECMO: Narrative Review.
Vajter et al. · JHLT open
Added to ASH registry: 2026-05-28
Antiplatelet-anticoagulant, APAC, a mimic of endogenous heparin, is an antithrombotic with von Willebrand factor-mediated characteristics
Jouppila et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Antithrombotic Therapy in Acute Coronary Syndrome Patients with End-Stage Renal Disease: Navigating Efficacy and Safety.
Abdeldayem et al. · Journal of clinical medicine
Added to ASH registry: 2026-05-28
Apixaban and Recurrent Stroke Risk With Left Ventricular Dysfunction: A Secondary Analysis of the ARCADIA Trial
Sharma et al. · Stroke
Added to ASH registry: 2026-05-28
Apixaban for Extended Treatment of Provoked Venous Thromboembolism
Piazza et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Apixaban Versus Enoxaparin for Venous Thromboembolism Prophylaxis in Colorectal Surgery
Ziegler et al. · The Journal of surgical research
Added to ASH registry: 2026-05-28
Apixaban versus warfarin for treatment of venous thromboembolism in patients with severe renal impairment: a multicenter study
Hanke et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Argatroban for intraoperative anticoagulation in a patient with history of heparin-induced thrombocytopenia and end-stage renal disease undergoing left atrial appendage occlusion: a case report
Eappen K et al. · Frontiers in medicine
Added to ASH registry: 2026-05-28
Argatroban-Associated Adverse Events: An Analysis Based on FDA Adverse Event Reporting System (FAERS)
Ren et al. · Cardiovascular toxicology
Added to ASH registry: 2026-05-28
Association between the Use of Fondaparinux Plus Radial Access and Clinical Outcomes in Patients with Non-ST Elevation Acute Coronary Syndrome
Ritt et al. · Arquivos brasileiros de cardiologia
Added to ASH registry: 2026-05-28
Asundexian or Apixaban in Patients With Atrial Fibrillation According to Prior Oral Anticoagulant Use: A Subgroup Analysis of the OCEANIC-AF Randomized Clinical Trial
Alexander et al. · JAMA cardiology
Added to ASH registry: 2026-05-28
Asundexian versus Apixaban in Patients with Atrial Fibrillation
Straw et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Asundexian versus Apixaban in Patients with Atrial Fibrillation
Benkhoff et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Asundexian versus Apixaban in Patients with Atrial Fibrillation
Piccini et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Asundexian versus Apixaban in Patients with Atrial Fibrillation. Reply
Piccini et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Asundexian: A Friend or a Foe for Atrial Fibrillation?
Danish et al. · Clinical Medicine Insights. Cardiology
Added to ASH registry: 2026-05-28
Asundexian: a systematic review of safety, efficacy, and pharmacological insights in thrombosis
Aldeen et al. · Thrombosis journal
Added to ASH registry: 2026-05-28
AZALEA-TIMI 71 trial: less bleeding with abelacimab compared to rivaroxaban in atrial fibrillation, but stroke prevention is uncertain
Gragnano et al. · European heart journal. Cardiovascular pharmacotherapy
Added to ASH registry: 2026-05-28
Balancing Safety and Efficacy: Factor XIa INHIBITORS vs. DOACs in Patients with Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Khater et al. · Journal of clinical medicine
Added to ASH registry: 2026-05-28
Basics of diagnosis and treatment of venous thromboembolism.
Cox et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Biomarkers of sepsis-induced coagulopathy: diagnostic insights and potential therapeutic implications.
Curtiaud et al. · Annals of intensive care
Added to ASH registry: 2026-05-28
Bivalirudin functionalized hydrogel coating capable of catalytical NO-generation for enhanced anticorrosion and biocompatibility of magnesium alloy
Pan et al. · Materials today. Bio
Added to ASH registry: 2026-05-28
Catheter-based left atrial appendage CLOSURE in patients with atrial fibrillation at high risk of stroke and bleeding as compared to best medical therapy: Rationale and design of the prospective randomized CLOSURE-AF trial.
Landmesser et al. · American heart journal
Added to ASH registry: 2026-05-28
Certolizumab pegol to prevent adverse pregnancy outcomes in patients with antiphospholipid syndrome and lupus anticoagulant (IMPACT): results of a prospective, single-arm, open-label, phase 2 trial.
Branch et al. · Annals of the rheumatic diseases
Added to ASH registry: 2026-05-28
Chemical composition analysis of the proteins of leech extract with anti-pulmonary fibrosis and their effects on metabolomics based on chromatography-mass spectrometry
Lu Y et al. · Journal of pharmaceutical and biomedical analysis
Added to ASH registry: 2026-05-28
Coagulation factor XI and coronary artery disease: is there room for factor XI inhibitors?
Paszek et al. · Polish archives of internal medicine
Added to ASH registry: 2026-05-28
Collaboration on the optimal timing of anticoagulation after ischaemic stroke and atrial fibrillation: a systematic review and prospective individual participant data meta-analysis of randomised controlled trials (CATALYST).
Dehbi et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
Comparative Analysis of Thrombosis in ECPella Patients Between Bivalirudin versus Heparin Anticoagulation Strategies
Cho AJ et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-28
Comparative effectiveness and safety of rivaroxaban with other oral anticoagulants in older adults with nonvalvular atrial fibrillation: population-based analysis in response to updated Beers Criteria
Dawwas et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Comparative safety and effectiveness of apixaban and rivaroxaban for treatment of cancer-associated venous thromboembolism: A retrospective cohort study
Sun et al. · PLoS medicine
Added to ASH registry: 2026-05-28
Comparative Study of Hirudins and Encoding Genes inand
Yin J et al. · Biology
Added to ASH registry: 2026-05-28
Comparison of outcomes of arterial end-to-side versus end-to-end anastomosis in autologous deep inferior epigastric perforator (DIEP) flap breast reconstruction: DIEP-ES study protocol.
Didzun et al. · International journal of surgery protocols
Added to ASH registry: 2026-05-28
Comparison of safety and efficacy of ultrasound-accelerated thrombolysis vs. standard catheter-directed thrombolysis for the management of acute pulmonary embolism - a systematic review and meta-analysis.
Passey et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Comparison of Three Mathematical Models of the Pharmacokinetics of Heparin to Guide the Use of Protamine in a Large Simulated Cohort of Patients
Vander Zwaag et al. · Seminars in cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-28
Complement function and activation in human serum and plasma collected in different blood collection tubes
Andersson LI et al. · Journal of immunological methods
Added to ASH registry: 2026-05-28
Considerations of safety for women prescribed apixaban or rivaroxaban who breastfeed-a physiologically based pharmacokinetic analysis
Butler AS et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Construction of safer hirudin-derived peptides with enhanced anticoagulant properties based on C-terminal active residue adaptation and modification
Yi X et al. · Journal of advanced research
Added to ASH registry: 2026-05-28
Contemporary management of acute pulmonary embolism.
Guarnieri et al. · International journal of cardiology
Added to ASH registry: 2026-05-28
Correction: Monitoring the appropriate prescription of low molecular weight heparins and Fondaparinux through administrative data. A retrospective observational study in the Tuscany region
Moretti et al. · PloS one
Added to ASH registry: 2026-05-28
Corrigendum to 'Impact of asundexian on a panel of coagulation assays'[Research and Practice in Thrombosis and Haemostasis 9(5) (2025) 102950]
Vassart et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Delayed Administration of Apixaban, but Not Rivaroxaban, Reduces Transfusion Risk Without Increasing Thromboembolic Rates Following Revision Total Hip Arthroplasty
Telang et al. · The Journal of arthroplasty
Added to ASH registry: 2026-05-28
Design and Evaluation of Sticky End-Type Bivalent DNA Aptamers Containing M08s-1 as Anticoagulant Agents
Yokomori et al. · ChemMedChem
Added to ASH registry: 2026-05-28
Design, synthesis, and anti-inflammatory potential of PROTAC drug molecules based on fondaparinux sodium
Wu et al. · Frontiers in bioengineering and biotechnology
Added to ASH registry: 2026-05-28
Design, synthesis, and biological evaluation of substituted oxopyridine derivatives as selective FXIa inhibitors
Wang et al. · RSC medicinal chemistry
Added to ASH registry: 2026-05-28
Direct Oral Anticoagulants Versus Low-Molecular-Weight Heparin in Patients With Cancer-Associated Thrombosis: A Meta-Analysis of Randomized Controlled Trials.
Mousavi et al. · The American journal of cardiology
Added to ASH registry: 2026-05-28
Discovery of potent, highly selective, and orally bioavailable factor XIa inhibitors for anticoagulant therapy
Zhang et al. · European journal of medicinal chemistry
Added to ASH registry: 2026-05-28
DOAC-Stop reverses the anticoagulant effect of asundexian and milvexian
Fitzpatrick et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Dose response of nafamostat mesylate for anticoagulation monitoring in pediatric critical care during continuous venovenous hemodiafiltration
Lee et al. · Scientific reports
Added to ASH registry: 2026-05-28
EASL Clinical Practice Guidelines on vascular diseases of the liver.
? et al. · Journal of hepatology
Added to ASH registry: 2026-05-28
Ecarin-based coagulation monitoring of argatroban in patients with heparin-induced thrombocytopenia: a prospective observational study
Schiferer A et al. · British journal of anaesthesia
Added to ASH registry: 2026-05-28
Edoxaban-induced acute interstitial nephritis
Gen et al. · CEN case reports
Added to ASH registry: 2026-05-28
Effect of concurrent use of rivaroxaban or apixaban with amiodarone on international normalised ratio: a retrospective observational study
Kho C et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Effect of heparins, direct oral anticoagulants, and factor XII/factor XI inhibitors on catheter-initiated thrombin generation in platelet-rich plasma: an in vitro study
Hardy et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Effect of vepdegestrant, a PROTAC oestrogen receptor degrader, on dabigatran and rosuvastatin pharmacokinetics in healthy participants
Yang et al. · British journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Effectiveness and safety of bivalirudin anticoagulation therapy in adult patients receiving extracorporeal membrane oxygenation: A systematic review and meta-analysis.
Hu et al. · Medicine
Added to ASH registry: 2026-05-28
Effectiveness and Safety of Rivaroxaban Versus Warfarin in Venous Thromboembolism Patients with Comorbid Obstructive Sleep Apnea: A Retrospective Cohort Study
Coleman et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Effects of milvexian alone or with heparin on catheter-induced clotting and thrombin generation
Yin et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Efficacy and Safety of Andexanet Alfa Versus Four Factor Prothrombin Complex Concentrate for Emergent Reversal of Factor Xa Inhibitor Associated Intracranial Hemorrhage: A Systematic Review and Meta-Analysis.
Sarhan et al. · Neurocritical care
Added to ASH registry: 2026-05-28
Efficient Small-Molecule Reversal Agents for Anticoagulant Fondaparinux.
Carbajo et al. · ACS pharmacology & translational science
Added to ASH registry: 2026-05-28
Epidemiology of venous thromboembolism: implications for clinical practice.
Marschang et al. · Polish archives of internal medicine
Added to ASH registry: 2026-05-28
Evaluating the Safety and Efficacy of Asundexian in Cardiovascular Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Arif et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Evaluation of a Standardized Electronic Argatroban Dosing Nomogram for Heparin-Induced Thrombocytopenia: A Retrospective Study.
Francis E et al. · The American journal of nursing
Added to ASH registry: 2026-05-28
Evaluation of Antiviral Activity of Lactoferrin in Bovine Milk Toward Fondaparinux Using Ordered Porous Layer Interferometry
Zhang et al. · Analytical chemistry
Added to ASH registry: 2026-05-28
Evolution of neutrophil extracellular traps in the pathology of stroke
Ning W et al. · Neural regeneration research
Added to ASH registry: 2026-05-28
Explore potential immune-related targets of leeches in the treatment of type 2 diabetes based on network pharmacology and machine learning
Hu et al. · Frontiers in genetics
Added to ASH registry: 2026-05-28
Factor Xa Inhibitors and Low Molecular Weight Heparins in Perioperative Surgical Thromboprophylaxis: A Network Meta-analysis
Bajpai et al. · Cardiovascular & hematological agents in medicinal chemistry
Added to ASH registry: 2026-05-28
Factor XI inhibitors and atrial fibrillation: imminent breakthrough or false start?
Raffo et al. · European heart journal supplements : journal of the European Society of Cardiology
Added to ASH registry: 2026-05-28
Factor XI/XIa inhibitors for splanchnic vein thrombosis associated with liver cirrhosis: Is there any potential role?
PorresAguilar et al. · Revista de gastroenterologia de Mexico (English)
Added to ASH registry: 2026-05-28
Factor XI/XIa Inhibitors: A New Approach to Anticoagulation
Whiteson et al. · Cardiology in review
Added to ASH registry: 2026-05-28
Factor XI/XIa inhibitors: a potential solution to anticoagulation dilemmas
Gibson et al. · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-28
FDA approves first factor XIIa inhibitor, for hereditary angioedema
Mullard et al. · Nature reviews. Drug discovery
Added to ASH registry: 2026-05-28
Fondaparinux Approval in Pediatrics: The Story of My Third Child
Young. · Pediatric blood & cancer
Added to ASH registry: 2026-05-28
Functional characterization of a common XIa inhibitory Kunitz-domain Shp4 from nine schistosoma secreted proteins with diverse C-terminal fragments
Ye et al. · PLoS neglected tropical diseases
Added to ASH registry: 2026-05-28
Guided reversal of dabigatran in massive hemorrhagic shock
Fernndez et al. · Medicina intensiva
Added to ASH registry: 2026-05-28
Haemophilia.
Chowdary P et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
Heparin and Direct Oral Anticoagulants have Different Effects on the Phases of Activation and Spatial Spread of Blood Coagulation
Ataullakhanov et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Heparin Resistance in Cardiac Surgery with Cardiopulmonary Bypass: Mechanisms, Clinical Implications, and Evidence-Based Management.
Rivera Jiménez et al. · Medicina (Kaunas, Lithuania)
Added to ASH registry: 2026-05-28
Herb-Drug Interaction Between Sailuotong and Pitavastatin: A Systematic Pharmacokinetic Investigation and Mechanism Analysis
Zhang et al. · Drug design, development and therapy
Added to ASH registry: 2026-05-28
Hirudin Alleviates Early Brain Injury After Subarachnoid Hemorrhage in Rats via Regulating NLRP3 Inflammasome-Mediated Pyroptosis
Pan M et al. · Physiological research
Added to ASH registry: 2026-05-28
Hirudin alleviates renal fibrosis by inducing autophagy to suppress NLRP3 inflammasome activation
Long C et al. · Bioscience, biotechnology, and biochemistry
Added to ASH registry: 2026-05-28
How I diagnose and treat acute infection-associated purpura fulminans.
Bendapudi et al. · Blood
Added to ASH registry: 2026-05-28
Impact of Age and Factor Xa Inhibitor Concentrations on Bleeding Risk in Patients with Atrial Fibrillation
Lin et al. · Clinical pharmacology and therapeutics
Added to ASH registry: 2026-05-28
Impact of asundexian on a panel of coagulation assays
Vassart et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Impact of Banhabaekchulcheonmatang (Banxia Baizhu Tianma Tang) and Hwangryeonhaedoktang (Huang Lian Jie Du Tang) on edoxaban: Herb-drug interaction study in healthy subjects
Cho et al. · Journal of ethnopharmacology
Added to ASH registry: 2026-05-28
Impact of Prophylactic Apixaban for 14 Days After Sleeve Gastrectomy on Thromboembolic Events and Its Side Effects
Galvao et al. · Obesity surgery
Added to ASH registry: 2026-05-28
Impairment of Collagen-Induced Thrombus Formation in Microfluidic Assay Correlates with Bleeding Complications Better Than Cytofluorometric Parameters
Melnikova EA et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Inappropriate dosing of direct oral anticoagulants among very older inpatients with atrial fibrillation
Zhang et al. · BMC geriatrics
Added to ASH registry: 2026-05-28
Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease
Li Y et al. · European journal of histochemistry : EJH
Added to ASH registry: 2026-05-28
Individualizing Thromboprophylaxis: From Fixed Doses to Targeted Low-Molecular-Weight Heparin Use
Kotsiou OS et al. · Cardiovascular drugs and therapy
Added to ASH registry: 2026-05-28
Inhibition of Activated Coagulation Factor XII by the Phosphodiesterase-4 Inhibitor Roflumilast: In Vitro and In Silico Studies
Madkhali et al. · Frontiers in bioscience (Landmark edition)
Added to ASH registry: 2026-05-28
Interferences associated with the factor XIa inhibitors asundexian and milvexian in routine and specialized coagulation assays and their removal by activated charcoal-based adsorbents
Buckley et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Intra-Arterial Tenecteplase Following Endovascular Reperfusion for Large Vessel Occlusion Acute Ischemic Stroke: The POST-TNK Randomized Clinical Trial.
Huang J et al. · JAMA
Added to ASH registry: 2026-05-28
Intraoperative antithrombotic drug removal during heart transplantation: A case series from the International Safe and Timely Antithrombotic Removal (STAR) registry
Schmitto et al. · JHLT open
Added to ASH registry: 2026-05-28
Intravenous Tenecteplase before Thrombectomy in Stroke.
Qiu Z et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Investigation into the binding domains of platelet factor 4 unlocks new avenues for the design and synthesis of selective sulfated pseudo-tetrasaccharide aminoglycoside ligands
Philip et al. · European journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Is fondaparinux safe for use during pregnancy? A state-of-the-art review of current evidence
Wu et al. · Archives of gynecology and obstetrics
Added to ASH registry: 2026-05-28
Left atrial appendage closure vs oral anticoagulation for stroke prevention in atrial fibrillation: Long-term outcomes from 4 randomized trials.
Kaisaier et al. · Heart rhythm
Added to ASH registry: 2026-05-28
Left atrial appendage occlusion in atrial fibrillation: shaping the future of stroke prevention.
Mitsis A et al. · Future cardiology
Added to ASH registry: 2026-05-28
Low concentrations of recombinant activated factor VII normalize coagulation patterns by reversing the changes in viscoelastic testing parameters induced by abelacimab in vitro
Khder et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Low-molecular-weight heparin-induced thrombocytopenia with multisite embolism: successful management with argatroban and dabigatran - a case report and literature review
Zhao et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-28
Maculopathy after long-term use of fondaparinux, a heparin mimetic and heparanase inhibitor
Lin et al. · American journal of ophthalmology case reports
Added to ASH registry: 2026-05-28
Medicinal Leech Therapy in Acute Herpes Zoster Condition- A Case Report
Itankar PB et al. · Journal of pharmacy & bioallied sciences
Added to ASH registry: 2026-05-28
Molecular characterization and immunological functions of the antimicrobial peptide theromacin from razor clam Sinonovacula constricta.
Hu H et al. · International journal of biological macromolecules
Added to ASH registry: 2026-05-28
Mortality, diagnosis, and etiology of disseminated intravascular coagulation-a systematic review and meta-analysis: communication from the ISTH SSC subcommittee on disseminated intravascular coagulation.
Umemura et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
NEJM at ESC - Asundexian versus Apixaban in Patients with Atrial Fibrillation
Rubin et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Occurrence of Platelet-Monocyte Aggregates in Patients with Metabolic Disorders and Effect of Direct Anticoagulants
Gunaseelan et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Oral anticoagulant reversal and mortality in trauma patients: a multicentre propensity score-matched cohort study
Lang et al. · EClinicalMedicine
Added to ASH registry: 2026-05-28
Oral anticoagulation versus no anticoagulation for stroke prevention in patients with intracranial haemorrhage and atrial fibrillation: an updated meta-analysis of randomised controlled trials.
D'Anna et al. · Journal of neurology, neurosurgery, and psychiatry
Added to ASH registry: 2026-05-28
Oral factor xia inhibitor milvexian after a recent acute coronary syndrome: Rationale and design of the phase 3 (Librexia ACS)
Gibson et al. · American heart journal
Added to ASH registry: 2026-05-28
Pentasaccharide anticoagulant fondaparinux inhibits diphtheria toxin
Heber et al. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Added to ASH registry: 2026-05-28
Perioperative Factor Xa Inhibitor Discontinuation for Patients Undergoing Procedures With Minimal or Low Bleeding Risk
Lee et al. · JAMA network open
Added to ASH registry: 2026-05-28
Pharmacokinetic prediction and dosage adjustment of enoxaparin administration in pregnant women with renal insufficiency: A FAERS-PBPK modeling study
Guo G et al. · Journal of pharmaceutical sciences
Added to ASH registry: 2026-05-28
Pharmacokinetics, pharmacodynamics and safety profile of SKB336, a selective inhibitor of coagulation factor XI/XIa in healthy subjects
Xiang et al. · British journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Milvexian in Healthy Chinese Adults
Luo et al. · Drug design, development and therapy
Added to ASH registry: 2026-05-28
Population Pharmacokinetics of Asundexian in People at Risk for Thromboembolic/Cardiovascular Events
Yassen et al. · CPT: pharmacometrics & systems pharmacology
Added to ASH registry: 2026-05-28
Position statement of the Polish Society of Gastroenterology on the use of andexanet alfa in patients with gastrointestinal bleeding taking factor Xa inhibitors
Adrych K et al. · Przeglad gastroenterologiczny
Added to ASH registry: 2026-05-28
Postoperative Direct Oral Anticoagulants are Associated with Improved Amputation-Free Survival in Infrageniculate Bypasses Performed by Prosthetic Grafts in Patients with Chronic Limb-Threatening Ischemia
Zarrintan et al. · Annals of vascular surgery
Added to ASH registry: 2026-05-28
Predicting drug-drug interactions and optimal dosing of betrixaban with physiologically based pharmacokinetic modeling in patients with renal impairment who were coadministered with P-glycoprotein inhibitors
Yan et al. · The Journal of international medical research
Added to ASH registry: 2026-05-28
Primary Anticoagulation With Bivalirudin Versus Heparin for Microaxial Flow Pump Supported Patients
Gramegna M et al. · ASAIO journal (American Society for Artificial Internal Organs : 1992)
Added to ASH registry: 2026-05-28
Proposal for a tooth extraction protocol for patients taking direct oral anticoagulants: a clinical trial
Higashi EM et al. · Oral surgery, oral medicine, oral pathology and oral radiology
Added to ASH registry: 2026-05-28
Proteolytic signatures of coagulation identified by plasma peptidomics
Del Castillo Alferez J et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Radial Access and Fondaparinux: A Synergistic Interaction
Andrade et al. · Arquivos brasileiros de cardiologia
Added to ASH registry: 2026-05-28
Rapid clearance of achiral small-molecule drugs using de novo-designed proteins and their cyclic and mirror-image variants.
Chen G et al. · Nature biomedical engineering
Added to ASH registry: 2026-05-28
Rapid Determination of Xa Inhibitor Activity in Blood Using a Microfluidic Device that Measures Platelet Deposition and Fibrin Generation Under Flow
Rossi et al. · TH open : companion journal to thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Real-world evaluation of therapeutic anticoagulation for cancer-associated thromboembolism: A retrospective analysis.
Chung J et al. · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
Added to ASH registry: 2026-05-28
Rebalancing agents in hemophilia: knowns, unknowns, and uncertainties.
Van Thillo et al. · Haematologica
Added to ASH registry: 2026-05-28
Refractory autoimmune heparin-induced thrombocytopenia following cardiac surgery
Zlamal et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Reversal of antithrombotic medications in patients with traumatic brain injury: What you need to know
Popma et al. · The journal of trauma and acute care surgery
Added to ASH registry: 2026-05-28
Reversal of Factor Xa Inhibitor-Related Intracranial Hemorrhage: A Multicenter, Retrospective, Observational Study Comparing the Efficacy and Safety of Andexanet and Prothrombin Complex Concentrates.
Panos et al. · Critical care medicine
Added to ASH registry: 2026-05-28
Revisiting Heparin-Induced Thrombocytopenia among Patients Undergoing Free Tissue Transfer: A Systematic Review.
Yamin et al. · Journal of reconstructive microsurgery
Added to ASH registry: 2026-05-28
Rivaroxaban vs. Enoxaparin for Preventing Venous Thromboembolism and Wound Complications after Knee Surgery: A Meta-Analysis
He et al. · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Added to ASH registry: 2026-05-28
Safety of Factor XI Inhibition With Abelacimab in Atrial Fibrillation by Kidney Function: A Prespecified Analysis of the AZALEA-TIMI 71 Randomized Clinical Trial
Patel et al. · JAMA cardiology
Added to ASH registry: 2026-05-28
Safety Profile and Bleeding Complications of Fondaparinux Versus Enoxaparin in Non-ST Elevation Acute Coronary Syndrome
Rahman et al. · Cureus
Added to ASH registry: 2026-05-28
Splanchnic vein thrombosis (2003-2022): a Swiss nationwide epidemiological study.
Cardi et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Splanchnic vein thrombosis in patients with pancreatitis: Outcome and impact of anticoagulation.
Maire et al. · Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
Added to ASH registry: 2026-05-28
Structure-based design and synthesis of novel FXIa inhibitors targeting the S2' subsite for enhanced antithrombotic efficacy
Wu et al. · Molecular diversity
Added to ASH registry: 2026-05-28
Subclinical atrial fibrillation: Who benefits from oral anticoagulation?
Atar et al. · Kardiologia polska
Added to ASH registry: 2026-05-28
Successful Treatment With the Oral Factor Xa Inhibitor Edoxaban in Heparin-Induced Thrombocytopenia With Thrombosis
Porres-Aguilar et al. · Angiology
Added to ASH registry: 2026-05-28
Superficial Vein Thrombosis: A Review.
Piazza et al. · JAMA
Added to ASH registry: 2026-05-28
TEG and ROTEM: Technology and Clinical Applications, 2026 Update.
Longacre et al. · American journal of hematology
Added to ASH registry: 2026-05-28
Tenecteplase vs Reteplase in Patients with Acute ST-Elevation Myocardial Infarction: A Retrospective Cohort Study.
Mohamed A et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
The Discovery of a Novel Anticoagulant Mechanism: Factor XI Activation Inhibitors
Ellsworth et al. · ACS pharmacology & translational science
Added to ASH registry: 2026-05-28
The Effects of Heparin Binding and Arg596 Mutations on the Conformation of Thrombin-Antithrombin Michaelis Complex, Revealed by Enhanced Sampling Molecular Dynamics Simulations.
Balogh G et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-28
The genetic spectrum of rare bleeding disorders.
Mohsenian et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
The incidence of venous thromboembolism by type of solid cancer worldwide: A systematic review.
Harry et al. · Cancer epidemiology
Added to ASH registry: 2026-05-28
The nacre protein Hcperlucin provides antibacterial defense following Aeromonas hydrophila infection and crystal morphological modification during shell biomineralization in Hyriopsis cumingii.
Tan X et al. · Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Added to ASH registry: 2026-05-28
The routine use of Rivaroxaban as thromboprophylaxis following endovenous thermal ablation
Bontinis et al. · VASA. Zeitschrift fur Gefasskrankheiten
Added to ASH registry: 2026-05-28
The safety and efficacy of factor XIa inhibitors for the prevention of stroke and thromboembolism: A systematic review and meta-analysis of randomized controlled trials
Zahid et al. · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Added to ASH registry: 2026-05-28
Thrombolysis Alone vs With Argatroban or Eptifibatide: A Prespecified Subgroup Analysis of the MOST Trial
Roy et al. · Neurology
Added to ASH registry: 2026-05-28
Thrombolysis for Ischemic Stroke Beyond the 4.5-Hour Window: A Meta-Analysis of Randomized Clinical Trials.
Günkan A et al. · Stroke
Added to ASH registry: 2026-05-28
Thrombosis and bleeding outcomes with warfarin conversion to rivaroxaban during the COVID-19 pandemic
Wang et al. · South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
Added to ASH registry: 2026-05-28
Time to hemostatic agent administration increases mortality in veterans with factor Xa inhibitor-related intracranial hemorrhage
Markovic N et al. · The American journal of emergency medicine
Added to ASH registry: 2026-05-28
Treatment of Venous Thromboembolism with Edoxaban over 18 Months: Results from ETNA-VTE Europe
Agnelli et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Trends and variation in the use of andexanet alfa for the reversal of direct oral anticoagulants in NHS trusts in England
Fisher L et al. · British journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Use of Bivalirudin for a Pediatric Patient with Two Mechanical Heart Valves: a case report
Branstetter JW et al. · Cardiology in the young
Added to ASH registry: 2026-05-28
Use of factor XI/XIa inhibitors in patients with atrial fibrillation: Current progress and future prospects
Fan et al. · Ageing research reviews
Added to ASH registry: 2026-05-28
Utilizing Argatroban for Neuroendovascular Therapy in Heparin-Induced Thrombocytopenia: A Case Report and Technical Review
Eguchi et al. · Journal of neuroendovascular therapy
Added to ASH registry: 2026-05-28
Vascular endothelial cell-targeted mRNA delivery via synthetic lipid nanoparticles for venous thrombosis prevention.
Guo et al. · Journal of controlled release : official journal of the Controlled Release Society
Added to ASH registry: 2026-05-28
Venous Thromboembolism Chemoprophylaxis in Plastic Surgery: A Randomized Controlled Trial of Apixaban versus Enoxaparin
Momeni et al. · Plastic and reconstructive surgery
Added to ASH registry: 2026-05-28
Venous Thromboembolism Therapy with Edoxaban in Daily Care Patients: Results from the DRESDEN NOAC REGISTRY.
Tittl et al. · TH open : companion journal to thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Volume and Location Analysis of Intracerebral Hemorrhage for the Appropriate Use of Andexanet Alfa
Umemura T et al. · Neurologia medico-chirurgica
Added to ASH registry: 2026-05-28
Weekly Journal Scan: the rise and OCEANIC fall of asundexian in atrial fibrillation
Liuzzo et al. · European heart journal
Added to ASH registry: 2026-05-28
Whole-genome sequencing-based species classification, multilocus sequence typing, and antibiotic resistance mechanisms of the clinicalcomplex.
Lu J et al. · Frontiers in microbiology
Added to ASH registry: 2026-05-28
A biomimetic macrophage-membrane-fused liposomal system loaded with GVs-HV recombinant plasmid for targeted anti-atherosclerosis therapy
Zhang Y et al. · Pharmaceutics
Added to ASH registry: 2026-05-27
A Comparative Analysis of Bivalirudin and Heparin for Extracorporeal Membrane Oxygenation in a Pediatric Cardiothoracic Intensive Care Unit
Daniels Z et al. · ASAIO journal
Added to ASH registry: 2026-05-27
Analysis of inter-hospital transfer on clinical outcomes after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction
Su X et al. · PLoS medicine
Added to ASH registry: 2026-05-27
Anticoagulants in children with renal impairment: a narrative review
Kiskaddon AL et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-27
Anticoagulants in Children with Renal Impairment: A Narrative Review
Kiskaddon AL et al. · Seminars in Thrombosis and Hemostasis
Added to ASH registry: 2026-05-27
Anticoagulants: from chance discovery to structure-based design
Chan N et al. · Pharmacological reviews
Added to ASH registry: 2026-05-27
Anticoagulation for heparin-induced thrombocytopenia before, during, and after peripheral endovascular procedures
Cardi S et al. · VASA
Added to ASH registry: 2026-05-27
Anticoagulation for heparin-induced thrombocytopenia before, during, and after peripheral endovascular procedures
Cardi S et al. · VASA — Zeitschrift fur Gefasskrankheiten
Added to ASH registry: 2026-05-27
Application of promoting blood circulation and resolving blood stasis in intracerebral hemorrhage: a traditional method gradually moving toward modern stroke care
Dingshan Z et al. · Journal of traditional Chinese medicine
Added to ASH registry: 2026-05-27
Argatroban plus dual antiplatelet therapy: Preliminary evidence for managing early neurological deterioration after lacunar stroke
Zhang H et al. · Clinical neurology and neurosurgery
Added to ASH registry: 2026-05-27
Bivalirudin infusion at standard or low regimen during elective percutaneous coronary intervention in high-risk bleeding patients
Li Y et al. · Contemporary clinical trials
Added to ASH registry: 2026-05-27
Bivalirudin versus heparin in patients undergoing percutaneous coronary intervention in acute coronary syndromes
Krittanawong C et al. · Critical pathways in cardiology
Added to ASH registry: 2026-05-27
Bloodletting therapy using subcutaneous heparin and controlled scarification for venous insufficiency in free flap reconstruction
Yalcin CE · Microsurgery
Added to ASH registry: 2026-05-27
BMI differences on anticoagulation with bivalirudin vs. heparin during primary PCI: a BRIGHT-4 subanalysis
Zhang D et al. · BMC medicine
Added to ASH registry: 2026-05-27
Catheter-Directed Bivalirudin for Local Anticoagulation and Clot Dissolution in Children Requiring Mechanical Circulatory Support
Chaudhry-Waterman N et al. · ASAIO journal
Added to ASH registry: 2026-05-27
Chromosome-level genome assembly and anticoagulant protein annotation of the buffalo leech Hirudinaria bpling (Hirudinea: Hirudinidae)
Khan MS et al. · BMC genomics
Added to ASH registry: 2026-05-27
Chromosome-level genome assembly and anticoagulant protein annotation of the buffalo leech Hirudinaria bpling (Hirudinea: Hirudinidae)
Khan MS et al. · BMC Genomics
Added to ASH registry: 2026-05-27
Comparative analysis of anti-thrombotic effect and metabonomic mechanism of aqueous extract of leech before and after talc processing
Liu Y et al. · Zhongguo Zhong yao za zhi
Added to ASH registry: 2026-05-27
Comparative Study of Lefaxin Family in Two Asian Leeches:and
Ye T et al. · Biology
Added to ASH registry: 2026-05-27
Dabigatran-idarucizumab pharmacokinetics-pharmacodynamics in sheep undergoing cardiopulmonary bypass
Eaton MP et al. · Perfusion
Added to ASH registry: 2026-05-27
Discovery of a Thrombin-Targeting Anticoagulant Peptide From Whitmania pigra via a Computation-Guided Experimentation Strategy
Hua Y et al. · Journal of peptide science
Added to ASH registry: 2026-05-27
Distribution and blood penetration of hirudin in various organs and tissues of rabbits with carotid artery injury
Feng Y et al. · Journal of analytical methods in chemistry
Added to ASH registry: 2026-05-27
Dosing Reliability of Direct Thrombin Inhibitors in Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-Analysis
Wieruszewski PM et al. · ASAIO journal (American Society for Artificial Internal Organs : 1992)
Added to ASH registry: 2026-05-27
Engineering ultrapotent trivalent anticoagulants through hybridisation of salivary peptides from multiple haematophagous organisms
Maxwell JWC et al. · Chemical science
Added to ASH registry: 2026-05-27
Evaluation of a Bivalirudin Dosing and Monitoring Protocol in Pediatric Extracorporeal Membrane Oxygenation
Smith LM et al. · The journal of pediatric pharmacology and therapeutics
Added to ASH registry: 2026-05-27
Evaluation of Intraoperative Bivalirudin Anticoagulation in Neonates and Infants Undergoing Arterial Switch Operation on Integrated ECMO-CPB Circuit: A Prospective Study
Badge HM et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
Expression of Recombinant Hirudin in Bacteria and Yeast: A Comparative Approach
Wang Z et al. · Methods Protoc
Added to ASH registry: 2026-05-27
Hemocompatibility related complications in Impella 5+ patients treated with Bivalirudin and dual antiplatelet therapy: a SHEAR score evaluation
Bandini M et al. · Cardiovascular revascularization medicine
Added to ASH registry: 2026-05-27
Hemolysis Monitoring Practices during Extracorporeal Membrane Oxygenation: A Survey Report
Strong AE et al. · Blood purification
Added to ASH registry: 2026-05-27
Heparin Induced Thrombocytopenia In The Setting Of Urgent Cardiac Surgery: Can Bivalirudin Be A Safe Option? - A Case Report
Alves B et al. · Portuguese Journal of Cardiac Thoracic and Vascular Surgery
Added to ASH registry: 2026-05-27
Heparin Versus Bivalirudin in Pediatric Patients Assisted With Mechanical Circulatory Support: A Retrospective Before-and-after Study
Giorni C et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
Heparin Versus Bivalirudin in Pediatric Patients Assisted With Mechanical Circulatory Support: A Retrospective Before-and-after Study
Giorni C et al. · Journal of Cardiothoracic and Vascular Anesthesia
Added to ASH registry: 2026-05-27
Hirudin promotes cerebral angiogenesis and exerts neuroprotective effects in MCAO/R rats by activating the Wnt/-catenin pathway
He L et al. · J Stroke Cerebrovasc Dis
Added to ASH registry: 2026-05-27
Hirudin-based treatment of diabetes-induced erectile dysfunction through inhibition of the HIF-1α to regulate RhoA/ROCK signaling pathway
Sun L et al. · American journal of men's health
Added to ASH registry: 2026-05-27
Identification and Screening of Novel Antimicrobial Peptides from Medicinal Leech via Heterologous Expression in E. coli
Serebrennikova M et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-27
Impact of pre-PCI activated clotting time on outcomes of bivalirudin versus heparin during primary PCI
Liu et al. · Journal of the Society for Cardiovascular Angiography & Interventions
Added to ASH registry: 2026-05-27
Improved outcomes with pulsatile paracorporeal ventricular assist device support in children: A single-center experience
Iaprintsev V et al. · JTCVS Open
Added to ASH registry: 2026-05-27
Leech Extract Enhances the Pro-Angiogenic Effects of Endothelial Cell-Derived Exosomes in a Mouse Model of Ischemic Stroke
Cao Y et al. · Current issues in molecular biology
Added to ASH registry: 2026-05-27
Managing necrotizing soft tissue infections of the lower limb: microsurgical reconstruction and hospital resource demands
Karamitros G et al. · Journal of clinical medicine
Added to ASH registry: 2026-05-27
Molecular cloning and functional analysis of a destabilase from Hirudinaria manillensis
Gao T et al. · Protein expression and purification
Added to ASH registry: 2026-05-27
Monomeric and Oligomeric Decorsins of the Asian Medicinal Leech
Tolksdorf C et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-27
Multi-target anticoagulant regulation by peptides from medicinal leeches: a unique natural strategy
Shi et al. · Pharmaceutical research
Added to ASH registry: 2026-05-27
Multi-Target Anticoagulant Regulation by Peptides from Medicinal Leeches: A Unique Natural Strategy against Thrombosis
Shi P et al. · Pharmaceutical research
Added to ASH registry: 2026-05-27
Outcomes of patients with suspected heparin-induced thrombocytopenia in a contemporary multicenter cohort
Nilius H et al. · Blood advances
Added to ASH registry: 2026-05-27
Platelet derived prothrombotic microparticles and adverse events in patients supported with Impella 5.5
D'Ettore N et al. · The International journal of artificial organs
Added to ASH registry: 2026-05-27
Production and functional characteristics of a novel hirudin variant with better anticoagulant activities than bivalirudin
Ge P et al. · Journal of enzyme inhibition and medicinal chemistry
Added to ASH registry: 2026-05-27
Production and functional characteristics of a novel hirudin variant with better anticoagulant activities than bivalirudin
Ge L et al. · Journal of enzyme inhibition and medicinal chemistry
Added to ASH registry: 2026-05-27
Production, Purification, and Characterization of a Novel Cysteine-Rich Anticoagulant from the Medicinal Leech and the Functional Role of Its Disulfide Bonds
Manuvera VA et al. · Biomolecules
Added to ASH registry: 2026-05-27
Quantitative methods to improve bivalirudin dosing in pediatric cardiac ICU patients
Brinkley L et al. · Perfusion
Added to ASH registry: 2026-05-27
Recombinant hirudin prevents against nonalcoholic fatty liver disease by modulating PAR1/JAK2/STAT5/STAT3/CD36 pathway
Xiaoyu YU et al. · Biochimica et biophysica acta. Molecular and cell biology of lipids
Added to ASH registry: 2026-05-27
Reconstruction of Wagner Grade 4 diabetic foot ulcers with the superficial circumflex iliac artery perforator free flap
Evin N et al. · Microsurgery
Added to ASH registry: 2026-05-27
Retrospective, Single-Center Cohort Study of Bivalirudin Compared to Unfractionated Heparin in Patients Receiving Extracorporeal Membrane Oxygenation
Lofy T et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-27
Safety and Efficacy of Bivalirudin as a Heparin Alternative in Patients Undergoing Carotid Artery Stenting
Kania TA et al. · Annals of vascular surgery
Added to ASH registry: 2026-05-27
Safety and efficacy of bivalirudin in female acute coronary syndrome patients undergoing percutaneous coronary intervention
Mostofa ABM et al. · Mymensingh medical journal
Added to ASH registry: 2026-05-27
Shuxuetong injection inhibits pyroptosis in acute ischemic stroke via CD44/NLRP3/GSDMD signal
Shang J et al. · Journal of ethnopharmacology
Added to ASH registry: 2026-05-27
Shuxuetong injection promotes skin flap survival by inhibiting pyroptosis mediated by the TLR4/NF-B/NLRP3 signaling pathway
Wang K et al. · Journal of ethnopharmacology
Added to ASH registry: 2026-05-27
Species delimitation recovers undescribed Erpobdellidae (Annelida: Hirudinea) from USA and Turkiye
Saglam N et al. · Zootaxa
Added to ASH registry: 2026-05-27
Staged mechanical circulatory support in paediatric HIT: Bivalirudin anticoagulation across ECMO, VAD, and cardiac transplantation
Beeman A et al. · Perfusion
Added to ASH registry: 2026-05-27
Staged mechanical circulatory support in paediatric HIT: Bivalirudin anticoagulation across ECMO, VAD, and cardiac transplantation
Beeman AA et al. · Perfusion
Added to ASH registry: 2026-05-27
Steroid Utilization for Pediatric Ventricular Assist Device-Associated Inflammation and Association With Outcomes
Ankola AA et al. · ASAIO Journal
Added to ASH registry: 2026-05-27
Successful pediatric heart transplantation with bivalirudin use in a cyanotic single ventricle patient with an intracorporeal continuous flow ventricular assist device and heparin-induced thrombocytopenia
Sainathan S, Mulinari L · Indian Journal of Thoracic and Cardiovascular Surgery
Added to ASH registry: 2026-05-27
Supramolecular Prodrug Hydrogel for One-Week Protection Against Thrombosis
Zhang W et al. · Small
Added to ASH registry: 2026-05-27
The derivatives of hirudin-like peptides from the Poecilobdella manillensis exhibit antithrombotic and anti-ischemic stroke effects
Khalid M et al. · International journal of biological macromolecules
Added to ASH registry: 2026-05-27
The effects of bivalirudin and ordinary heparin on the incidence of bleeding events and the level of inflammation after interventional therapy
Wu Q et al. · Alternative therapies in health and medicine
Added to ASH registry: 2026-05-27
The efficacy and safety of bivalirudin and heparin in patients with acute coronary syndrome: a systematic review and meta-analysis
Zhai Y et al. · Systematic reviews
Added to ASH registry: 2026-05-27
Ticagrelor vs. clopidogrel in bivalirudin-treated patients with STEMI undergoing primary PCI: The BRIGHT-4 trial
Li Y et al. · Cardiovascular revascularization medicine
Added to ASH registry: 2026-05-27
Traditional Chinese Medicinal Leech Induces Apoptosis and Autophagy in Glioblastoma by SGK1/Caspase-3 and PI3K/AKT/mTOR Pathway
Wu S et al. · CNS neuroscience & therapeutics
Added to ASH registry: 2026-05-27
Traditional uses, chemical constituents, pharmacological activities and toxicology of Chinese medicinal leech (Shuizhi): A comprehensive review
Liu J et al. · Journal of ethnopharmacology
Added to ASH registry: 2026-05-27
Discovery of a Thrombin-Targeting Anticoagulant Peptide From Whitmania pigra via a 'Computation-Guided Experimentation' Strategy
Hua YT et al. · Journal of peptide science : an official publication of the European Peptide Society
Added to ASH registry: 2026-05-26
Leech bionic Hirudin fusion protein prodrug loaded microneedles for long-term inhibition of thrombosis
Tian X et al. · Journal of controlled release : official journal of the Controlled Release Society
Added to ASH registry: 2026-03-18
Novel drug delivery systems for hirudin-based product development and clinical applications
Mo L et al. · International journal of biological macromolecules
Added to ASH registry: 2026-03-18
2024
267 articlesA comparative study of the clinical benefits of rivaroxaban and dabigatran in patients with nonvalvular atrial fibrillation with high bleeding risk
Liu · Frontiers in cardiovascular medicine
Added to ASH registry: 2026-05-29
Adverse events of direct factor Xa inhibitors: a disproportionality analysis of the FAERS database
Qian et al. · Expert opinion on drug safety
Added to ASH registry: 2026-05-29
Apixaban vs Aspirin in Patients With Cancer and Cryptogenic Stroke: A Post Hoc Analysis of the ARCADIA Randomized Clinical Trial
Navi et al. · JAMA neurology
Added to ASH registry: 2026-05-29
Application of the Win Ratio Method in the ENGAGE AF-TIMI 48 Trial Comparing Edoxaban With Warfarin in Patients With Atrial Fibrillation
Bergmark et al. · Circulation. Cardiovascular quality and outcomes
Added to ASH registry: 2026-05-29
Appropriateness of direct oral anticoagulant dosing in patients with atrial fibrillation at a tertiary care hospital in Thailand
Pongsathabordee et al. · Exploratory research in clinical and social pharmacy
Added to ASH registry: 2026-05-29
Argatroban Use in Pediatric Patients Supported by Paracorporeal Ventricular Assist Devices
Tuttle et al. · ASAIO journal (American Society for Artificial Internal Organs : 1992)
Added to ASH registry: 2026-05-29
Bivalirudin for unsalvageable venous congestion or obstruction in head and neck free flap reconstruction
Harris et al. · Oral oncology
Added to ASH registry: 2026-05-29
Bivalirudin Stability in Citrated Plasma and Citrated Whole Blood
Bruzdoski et al. · Archives of pathology & laboratory medicine
Added to ASH registry: 2026-05-29
Bivalirudin: The misunderstood alternative to heparin
Faraoni et al. · Paediatric anaesthesia
Added to ASH registry: 2026-05-29
Can the combination of antiplatelet or alteplase thrombolytic therapy with argatroban benefit patients suffering from acute stroke? a systematic review, meta-analysis, and meta-regression
Xie et al. · PloS one
Added to ASH registry: 2026-05-29
Clinical Implications of Co-administering Apixaban with Key Interacting Medications
Favatella et al. · Clinical pharmacology in drug development
Added to ASH registry: 2026-05-29
Comment on: Bivalirudin during thrombolysis with catheter-directed tPA in a heparin-refractory patient: A case report
Han · Pediatric blood & cancer
Added to ASH registry: 2026-05-29
Comparison of Apixaban, Rivaroxaban, Dabigatran, and Vitamin K Antagonists in Patients With Atrial Fibrillation and Liver Disease: A Network Meta-Analysis
Shaikh et al. · Cureus
Added to ASH registry: 2026-05-29
Comparison of bleeding and thrombotic outcomes in veno-venous extracorporeal membrane oxygenation: Heparin versus bivalirudin
Kartika et al. · European journal of haematology
Added to ASH registry: 2026-05-29
Comparison of Effectiveness and Safety of Apixaban, Dabigatran, and Rivaroxaban in Patients With Valvular Atrial Fibrillation: A Network Meta-Analysis of Randomized-Control Trials and Observational Studies
Huma et al. · Cureus
Added to ASH registry: 2026-05-29
Detection of enoxaparin and argatroban by use of the novel viscoelastic coagulometer ClotPro
Gratz et al. · Scientific reports
Added to ASH registry: 2026-05-29
Drug-Drug Interactions in the Treatment of Cancer-Associated Venous Thromboembolism with Direct Oral Anticoagulants
Hellfritzsch et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-29
Editorial: Bivalirudin versus unfractionated heparin in acute myocardial infarction: Why are we still debating?
Cohen et al. · Cardiovascular revascularization medicine : including molecular interventions
Added to ASH registry: 2026-05-29
Edoxaban-Induced Vanishing Bile Duct Syndrome: A Case Report With Review of the Literature
Borgonovo et al. · Cureus
Added to ASH registry: 2026-05-29
Esophageal Damage Following Left Atrial Ablation in a Patient on Dabigatran: Adding Insult to Injury
Jalloul et al. · European journal of case reports in internal medicine
Added to ASH registry: 2026-05-29
Heparin Resistance after Andexanet Alfa - Calling on Argatroban and Nafamostat for Rescue?
Mishima et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-29
High-Dose Immunoglobulin Therapy for Multiple Thromboembolism in Persisting Heparin-Induced Thrombocytopenia
Kudo et al. · Cureus
Added to ASH registry: 2026-05-29
Intravenous thrombolysis following dabigatran reversal in a patient with acute embolic stroke after atrial fibrillation ablation
Chen et al. · Journal of arrhythmia
Added to ASH registry: 2026-05-29
L-shaped association between gamma-glutamyl transferase-to-albumin ratio and dabigatran-related bleeding in non-valvular atrial fibrillation patients: a multicenter cohort study
Yu et al. · Cardiovascular diagnosis and therapy
Added to ASH registry: 2026-05-29
Long-term effectiveness and safety of edoxaban in patients with atrial fibrillation: 4-year data from the ETNA-AF-Europe study
Kirchhof et al. · International journal of cardiology
Added to ASH registry: 2026-05-29
Management of Bivalirudin Dosing and Replacement Fluid During Therapeutic Plasma Exchange in Children on Extracorporeal Membrane Oxygenation
Chomat et al. · ASAIO journal (American Society for Artificial Internal Organs : 1992)
Added to ASH registry: 2026-05-29
Monitoring Argatroban Anticoagulation in the Critically Ill: All Tests Are Not Created Equal
Erdoes et al. · Anesthesiology
Added to ASH registry: 2026-05-29
Optimizing warfarin dosing for patients with atrial fibrillation using machine learning
Petch et al. · Scientific reports
Added to ASH registry: 2026-05-29
Population pharmacokinetics of unfractionated heparin and multivariable analysis of activated clotting time in patients undergoing radiofrequency ablation of atrial fibrillation
Konecki et al. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Added to ASH registry: 2026-05-29
Possible Factor Xa Resistance in a Patient Who Failed Apixaban and Rivaroxaban
Ali et al. · Clinical case reports
Added to ASH registry: 2026-05-29
Recombinant hirudin and PAR-1 regulate macrophage polarisation status in diffuse large B-cell lymphoma
Pei et al. · BMC biotechnology
Added to ASH registry: 2026-05-29
Smartphone App for Improving Self-Awareness of Adherence to Edoxaban Treatment in Patients With Atrial Fibrillation (ADHERE-App Trial): Randomized Controlled Trial
Yoon et al. · Journal of medical Internet research
Added to ASH registry: 2026-05-29
The effect of off-label use of reduced-dose direct oral anticoagulants therapy in the treatment of pulmonary embolism comparable to standard-dose therapy
Yamazoe et al. · Heart and vessels
Added to ASH registry: 2026-05-29
UGT2B15 single nucleotide polymorphism reduces dabigatran acylglucuronide formation in humans
Park et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-29
Unresponsiveness of Activated Partial Thromboplastin Time to Bivalirudin in Adults Receiving Extracorporeal Membrane Oxygenation
Jatis et al. · ASAIO journal (American Society for Artificial Internal Organs : 1992)
Added to ASH registry: 2026-05-29
Use of bivalirudin after initial heparin management among adult patients on long-term venovenous extracorporeal support as a bridge to lung transplant: A case series
Halawi et al. · Pharmacotherapy
Added to ASH registry: 2026-05-29
5-Year Results From the AMPLATZER Amulet Left Atrial Appendage Occluder Randomized Controlled Trial.
Lakkireddy D et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
A Comparison Between Fondaparinux Sodium and Low-Molecular-Weight Heparin in Preventing Patients Undergoing Hip Replacement from Deep Vein Thrombosis
Wang et al. · Journal of musculoskeletal & neuronal interactions
Added to ASH registry: 2026-05-28
A narrative review of acute pancreatitis-induced splanchnic vein thrombosis: from pathogenesis to clinical management.
Liu et al. · Scandinavian journal of gastroenterology
Added to ASH registry: 2026-05-28
A pharmacokinetic and pharmacodynamic evaluation of asundexian: a novel factor XIa inhibitor for stroke prevention
Cella et al. · Expert opinion on drug metabolism & toxicology
Added to ASH registry: 2026-05-28
A randomized trial of antithrombotic therapy in patients with acute coronary syndrome and coronary ectasia.
Araiza-Garaygordobil et al. · American heart journal
Added to ASH registry: 2026-05-28
A randomized trial of low-dose thrombolysis, ultrasound-assisted thrombolysis, or heparin for intermediate-high risk pulmonary embolism-the STRATIFY trial: design and statistical analysis plan.
Kjærgaard J et al. · Trials
Added to ASH registry: 2026-05-28
A Rare Case of Argatroban-Induced Anaphylaxis in a Patient With Intermediate-High Risk Pulmonary Embolism
Bulsara KG et al. · Cureus
Added to ASH registry: 2026-05-28
A small-molecule hemostatic agent for the reversal of direct oral anticoagulant-induced bleeding
Desvages et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Abelacimab: A leap forward in anticoagulation with FXI and FXIa Inhibition
Badreldin et al. · Current research in pharmacology and drug discovery
Added to ASH registry: 2026-05-28
Absolute oral bioavailability of milvexian spray-dried dispersion formulation under fasted and fed conditions in healthy adult participants: An intravenous microtracer approach
Jarugula et al. · Clinical and translational science
Added to ASH registry: 2026-05-28
Allosteric Modulation of Thrombin by Thrombomodulin: Insights from Logistic Regression and Statistical Analysis of Molecular Dynamics Simulations.
Wu D et al. · ACS omega
Added to ASH registry: 2026-05-28
An automated analysis method enabling the screening of covalent thrombin and factor XIIa inhibitors via liquid chromatography-mass spectrometry
Erbacher et al. · Drug testing and analysis
Added to ASH registry: 2026-05-28
Andexanet alfa for reversal of direct factor Xa inhibitor anticoagulation.
Unknown · Australian prescriber
Added to ASH registry: 2026-05-28
Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity: Prespecified Subgroup Analysis of the ANNEXA-4 Study in Japan.
Toyoda et al. · Journal of atherosclerosis and thrombosis
Added to ASH registry: 2026-05-28
Andexanet alfa or prothrombin complex concentrate for acute reversal of oral factor Xa inhibitors: monitoring of antidote effects.
Tanaka et al. · British journal of anaesthesia
Added to ASH registry: 2026-05-28
Andexanet Alfa versus Four-Factor Prothrombin Complex Concentrate for the Reversal of Factor Xa (FXa) Inhibitor-Associated Intracranial Hemorrhage: A Systematic Review of Retrospective Studies.
Ferreira et al. · Journal of clinical medicine
Added to ASH registry: 2026-05-28
Andexanet alfa versus PCC products for factor Xa inhibitor bleeding: A systematic review with meta-analysis
White et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage
Yates et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage
Wong et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage
Kreutziger et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage.
Connolly et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage. Reply
Shoamanesh et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Anti-PF4 ELISA-Negative, SRA-Positive Heparin-Induced Thrombocytopenia.
Attah et al. · Hematology reports
Added to ASH registry: 2026-05-28
Anti-Xa Activity Monitoring for Optimizing Rivaroxaban Dosage in Chinese Patients with Cerebral Venous Thrombosis
Zhang et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Anticoagulation Alone vs Anticoagulation Plus Aspirin or DAPT Following Left Atrial Appendage Occlusion.
Reinhardt SW et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
Anticoagulation of pediatric patients with venous thromboembolism in 2023.
van Ommen CH et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Anticoagulation reversal (vitamin K, prothrombin complex concentrates, idarucizumab, andexanet-α, protamine).
Bekka E et al. · British journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Antithrombotic prophylaxis following total knee arthroplasty: a level I Bayesian network meta-analysis.
Migliorini et al. · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Added to ASH registry: 2026-05-28
Antithrombotic therapy in patients with acute coronary syndrome: similarities and differences between a European expert consensus document and the 2023 European Society of Cardiology guidelines.
Landi et al. · European heart journal. Acute cardiovascular care
Added to ASH registry: 2026-05-28
Application of a Novel UPLC-MS/MS Method for Analysis of Rivaroxaban Concentrations in Dried Blood Spot and Plasma Samples Collected from Patients with Venous Thrombosis
Pawlak et al. · Molecules (Basel, Switzerland)
Added to ASH registry: 2026-05-28
Association of Argatroban Dose With Coagulation Laboratory Test in Patients on Extracorporeal Membrane Oxygenation: Activated Clotting Time vs Activated Partial Thromboplastin Time
Ahn et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Bleeding Complications between Bivalirudin and Heparin for Extracorporeal Membrane Oxygenation in Neonates with Congenital Diaphragmatic Hernia.
Credille et al. · Fetal diagnosis and therapy
Added to ASH registry: 2026-05-28
Bleeding Risk of Anticoagulation Reversal Strategies Before Heart Transplantation: A Retrospective Comparative Cohort Study
PrietoRomero et al. · Journal of cardiovascular development and disease
Added to ASH registry: 2026-05-28
Cancer-associated splanchnic vein thrombosis: Clinical implications and management considerations.
Cohen et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Catastrophic antiphospholipid syndrome: Lessons from the "CAPS Registry".
Rodriguez-Pintó et al. · Medicina clinica
Added to ASH registry: 2026-05-28
Cavernous Sinus Thrombosis.
Housley et al. · Neurosurgery clinics of North America
Added to ASH registry: 2026-05-28
Cerebral microbleeds and asundexian in non-cardioembolic ischemic stroke: Secondary analyses of the PACIFIC-STROKE randomized trial
Balali et al. · International journal of stroke : official journal of the International Stroke Society
Added to ASH registry: 2026-05-28
Cerebral Sinus Venous Thrombosis in Pediatric Acute Lymphoblastic Leukemia: Incidence, Clinical Characteristics, and Long-term Neurologic Outcomes.
Johnson-Bishop et al. · Journal of child neurology
Added to ASH registry: 2026-05-28
Cerebral Venous Sinus Thrombosis: Current Updates in the Asian Context.
Miraclin T et al. · Cerebrovascular diseases extra
Added to ASH registry: 2026-05-28
Cerebral Venous Sinus Thrombosis.
Nguyen et al. · Neurosurgery clinics of North America
Added to ASH registry: 2026-05-28
Clinical guideline on reversal of direct oral anticoagulants in patients with life threatening bleeding
Grottke et al. · European journal of anaesthesiology
Added to ASH registry: 2026-05-28
Clinical outcomes of patients receiving long-term fondaparinux for thrombotic antiphospholipid syndrome
Bor et al. · Lupus
Added to ASH registry: 2026-05-28
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 1: sepsis.
Yamakawa et al. · International journal of hematology
Added to ASH registry: 2026-05-28
Coagulation Tests and Reversal Agents in Patients Treated with Oral Anticoagulants: The Challenging Scenarios of Life-Threatening Bleeding and Unplanned Invasive Procedures
Pozzi et al. · Journal of clinical medicine
Added to ASH registry: 2026-05-28
Comparative Effectiveness and Safety of Apixaban, Rivaroxaban, and Warfarin in Patients With Cirrhosis and Atrial Fibrillation : A Nationwide Cohort Study
Simon et al. · Annals of internal medicine
Added to ASH registry: 2026-05-28
Comparative Effectiveness of Valoctocogene Roxaparvovec and Prophylactic Factor VIII Replacement in Severe Hemophilia A.
Oldenburg J et al. · Advances in therapy
Added to ASH registry: 2026-05-28
Comparison of anticoagulation vs mechanical thrombectomy for the treatment of iliofemoral deep vein thrombosis.
Abramowitz S et al. · Journal of vascular surgery. Venous and lymphatic disorders
Added to ASH registry: 2026-05-28
Comparison of Fixed Versus Weight-Based Prothrombin Complex Concentrate Dosing Strategies for Factor Xa Inhibitor Reversal
Brett et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Comprehensive Review of Tenecteplase for Thrombolysis in Acute Ischemic Stroke.
Wang L et al. · Journal of the American Heart Association
Added to ASH registry: 2026-05-28
Contemporary outcomes of acute ischemic stroke in atrial fibrillation patients on anticoagulation.
Vasquez et al. · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Added to ASH registry: 2026-05-28
Correction of Trauma-induced Coagulopathy by Goal-directed Therapy: A Secondary Analysis of the ITACTIC Trial.
Lindsay et al. · Anesthesiology
Added to ASH registry: 2026-05-28
Dabigatran etexilate versus warfarin in cerebral venous thrombosis in Chinese patients (CHOICE-CVT): An open-label, randomized controlled trial
Ma et al. · International journal of stroke : official journal of the International Stroke Society
Added to ASH registry: 2026-05-28
Demystifying the Contemporary Role of 12-Month Dual Antiplatelet Therapy After Acute Coronary Syndrome.
Valgimigli et al. · Circulation
Added to ASH registry: 2026-05-28
Design, expression and biological evaluation of DX-88mut as a novel selective factor XIa inhibitor for antithrombosis
Sun et al. · Bioorganic chemistry
Added to ASH registry: 2026-05-28
Development of a Medication-Use Evaluation Template for Andexanet Alfa in the Reversal of Anticoagulation With Factor Xa Inhibitors
Fera et al. · Journal of pharmacy practice
Added to ASH registry: 2026-05-28
Development of an Ultrasensitive Competitive Double-Enzyme Cascade Fluorescence Signal Amplification Method for Factor XIa Inhibitor Screening
Zhan et al. · Analytical chemistry
Added to ASH registry: 2026-05-28
Dilemmas in the diagnosis and management of antiphospholipid syndrome.
Manning et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Direct Oral Anticoagulants in Budd-Chiari Syndrome.
Thapa et al. · European journal of haematology
Added to ASH registry: 2026-05-28
Direct-Acting Oral Anticoagulant Dabigatran as a Bridging Therapy while Optimizing Warfarin Dosage for Cardioembolic Stroke
Venketasubramanian et al. · Cerebrovascular diseases extra
Added to ASH registry: 2026-05-28
Discovery and Characterization of Panaxatriol as a Novel Thrombin Inhibitor from Panax notoginseng Using a Combination of Computational and Experimental Approaches
Wang et al. · Planta medica
Added to ASH registry: 2026-05-28
Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors
Dumas et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Discovery of Highly Selective, Potent, Covalent, and Orally Bioavailable Factor XIIa Inhibitors for the Treatment of Thrombo-Inflammation
Meng et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Discovery of New Inhibitors of Human Activated Protein C to Treat Hemophilia
Aliter et al. · Letters in drug design & discovery
Added to ASH registry: 2026-05-28
Dual vs triple antithrombotic therapy in atrial fibrillation and acute coronary syndrome: An updated meta-analysis of randomized controlled trials.
Sainbayar et al. · Journal of investigative medicine : the official publication of the American Federation for Clinical Research
Added to ASH registry: 2026-05-28
Early Time Courses of Recurrent Venous Thromboembolism and Bleeding during Apixaban or Dalteparin Therapy for Patients with Cancer.
Cohen AT et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Edoxaban Antithrombotic Therapy for Atrial Fibrillation and Stable Coronary Artery Disease
Cho et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Efanesoctocog alfa: the renaissance of Factor VIII replacement therapy.
Dargaud Y et al. · Haematologica
Added to ASH registry: 2026-05-28
Effect of Age, Sex, Renal Impairment and Hepatic Impairment on the Safety, Pharmacokinetics and Pharmacodynamics of Asundexian
Brase et al. · Clinical pharmacokinetics
Added to ASH registry: 2026-05-28
Effect of low- versus high-dose 4-factor prothrombin complex concentrate in factor Xa inhibitor-associated bleeding: A qualitative systematic review
Phillips et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Efficacy and safety of antithrombotic therapy for preventing and treating pediatric thromboembolic disease: a systematic review.
Gao H et al. · Scientific reports
Added to ASH registry: 2026-05-28
Efficacy and safety of factor Xa inhibitors in low body weight patients
Tan et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Efficacy and safety of rivaroxaban versus apixaban for venous thromboembolism: A systematic review and meta-analysis of observational studies
Fredman et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Efficacy and Safety of Systemic Thrombolysis and Catheter-Directed Therapy in Pulmonary Embolism: A Narrative Review.
Upadhyay H et al. · Cureus
Added to ASH registry: 2026-05-28
Efficacy of Infrared Thermographic Camera in Early Detection of Vascular Obstruction Following Microvascular Flaps in Head and Neck Reconstruction: A Prospective Clinical Study
Thyagaraj J et al. · Journal of maxillofacial and oral surgery
Added to ASH registry: 2026-05-28
Efficacy of Therapeutic Plasma Exchange or Cangrelor as an Adjunctive Strategy to Facilitate Cardiopulmonary Bypass in Patients with Heparin-Induced Thrombocytopenia: A Systematic Review and Meta-Analysis
Del et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-28
Enoxaparin is not an oral factor Xa inhibitor. Response to Sutton et al. real-world clinical outcomes among US veterans with oral factor Xa inhibitor-related major bleeding treated with andexanet alfa or 4-factor prothrombin complex concentrate
Buka et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Evaluation and Management of Mechanical Heart Valve Dysfunction and Thrombosis.
Parizher et al. · Current cardiology reports
Added to ASH registry: 2026-05-28
Evaluation of Drug-Drug Interactions Between Clarithromycin and Direct Oral Anticoagulants Using Physiologically Based Pharmacokinetic Models.
Yang Z et al. · Pharmaceutics
Added to ASH registry: 2026-05-28
Evolution and advances in endovascular mechanical thrombectomy of cerebral venous sinus thrombosis.
Kan et al. · International journal of medical sciences
Added to ASH registry: 2026-05-28
Factor Xa Inhibitors versus warfarin in patients with morbid obesity and atrial fibrillation
Dobry et al. · European journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Factor XI inhibition in hemodialysis patients: the safer anticoagulation?
Stamellou et al. · Kidney international
Added to ASH registry: 2026-05-28
Factor XI inhibitors - Rising stars in anti-thrombotic therapy?
Nolte. · Journal of the neurological sciences
Added to ASH registry: 2026-05-28
Factor XI/XIa inhibitors for the prevention and treatment of venous and arterial thromboembolism: A narrative review
Prakash et al. · Vascular medicine (London, England)
Added to ASH registry: 2026-05-28
Factor XIa inhibitors: collecting the clinical evidence
Lewis et al. · European heart journal. Cardiovascular pharmacotherapy
Added to ASH registry: 2026-05-28
Heparin-Calibrated Anti-Factor Xa Assay for the Measurement of Direct Anticoagulants such as Apixaban, Rivaroxaban, and Edoxaban
Ahn et al. · Clinical laboratory
Added to ASH registry: 2026-05-28
Higher incidence of venous thromboembolism associated with increasing lines of treatment in heavily treated ovarian cancer patients.
Lampert et al. · International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Added to ASH registry: 2026-05-28
How I treat pediatric venous thromboembolism in the DOAC era.
Bhat RV et al. · Blood
Added to ASH registry: 2026-05-28
How we manage a high D-dimer.
Franchini et al. · Haematologica
Added to ASH registry: 2026-05-28
Idarucizumab in dabigatran-treated patients with acute stroke: a review and clinical update.
Frol et al. · Frontiers in neurology
Added to ASH registry: 2026-05-28
Identification and anticoagulant mechanisms of novel factor XIa inhibitory peptides by virtual screening of a in silico generated deep-sea peptide database
Ouyang et al. · Food research international (Ottawa, Ont.)
Added to ASH registry: 2026-05-28
Identification, screening, and comprehensive evaluation of novel thrombin inhibitory peptides from the hirudo produced using pepsin
Chai X et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-28
Immune-stealth VP28-conjugated heparin nanoparticles for enhanced and reversible anticoagulation.
Hussein et al. · Nanotechnology
Added to ASH registry: 2026-05-28
Impact of Bivalirudin on Ischemia/Reperfusion Injury in Patients with Reperfused STEMI Assessed by Cardiac Magnetic Resonance
Zhang et al. · Pharmaceuticals (Basel, Switzerland)
Added to ASH registry: 2026-05-28
Impact of elevated direct factor Xa inhibitor plasma levels on perioperative blood loss in patients undergoing urgent surgery
Mair et al. · Transfusion
Added to ASH registry: 2026-05-28
Incidence and risk factors of VTE in lung cancer: a meta-analysis.
Yang et al. · Annals of medicine
Added to ASH registry: 2026-05-28
Incidence of venous thromboembolism after cardiovascular surgery.
Saitoh et al. · Asian cardiovascular & thoracic annals
Added to ASH registry: 2026-05-28
Incidence of venous thromboembolism in pediatric orthopedics: A systematic review.
Boulet et al. · Orthopaedics & traumatology, surgery & research : OTSR
Added to ASH registry: 2026-05-28
Integrated microfluidic multiple electrode aggregometry for point-of-care platelet function analysis.
Zhao et al. · Lab on a chip
Added to ASH registry: 2026-05-28
Intravenous thrombolysis and mechanical thrombectomy in acute stroke patients on direct oral anticoagulants.
Kristoffersen et al. · Journal of neurology
Added to ASH registry: 2026-05-28
Investigating Protein-Nucleic Acid Binding Interactions with Diethylpyrocarbonate Covalent Labeling-Mass Spectrometry.
Kirsch ZJ et al. · Journal of the American Society for Mass Spectrometry
Added to ASH registry: 2026-05-28
Is bivalirudin ready for a comeback? Pros and cons.
Stone GW et al. · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Added to ASH registry: 2026-05-28
Is there a role for the laboratory monitoring in the management of specific antidotes of direct oral anticoagulants?.
Gendron et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Laboratory Evaluation of Interferences Associated with Factor XIa Inhibitors Asundexian and Milvexian in Routine Coagulation Assays
Buckley et al. · Diagnostics (Basel, Switzerland)
Added to ASH registry: 2026-05-28
Latest advances in the reversal strategies for direct oral anticoagulants.
Escal et al. · Fundamental & clinical pharmacology
Added to ASH registry: 2026-05-28
Lentiviral Gene Therapy with CD34+ Hematopoietic Cells for Hemophilia A.
Srivastava A et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Letter to the editor: 1-year clinical outcomes of bivalirudin vs. unfractionated heparin in patients with type 2 diabetes undergoing elective percutaneous coronary intervention.
Rajab F et al. · European heart journal. Cardiovascular pharmacotherapy
Added to ASH registry: 2026-05-28
Light transmission aggregometry for platelet function testing: position paper on current recommendations and French proposals for accreditation.
Stépanian et al. · Platelets
Added to ASH registry: 2026-05-28
Lupus anticoagulant and valvular cardiac surgery
Kamath et al. · Perfusion
Added to ASH registry: 2026-05-28
Macrocyclic Inhibitors Targeting the Prime Site of the Fibrinolytic Serine Protease Plasmin
Wiedemeyer et al. · ChemMedChem
Added to ASH registry: 2026-05-28
Management of direct oral anticoagulant drug interactions in hospitalized patients.
Al Zaria MH et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Management of Neonatal Aortic Thrombosis: Challenges and Outcomes With Systemic and Intra-arterial Thrombolysis.
Reddy et al. · Cureus
Added to ASH registry: 2026-05-28
Management options for pediatric venous thromboembolic disease: Beyond anticoagulation with endovascular therapies.
Mitta et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Mechanical Thrombectomy in Anticoagulated Patients With Acute Ischemic Stroke: A Meta-Analysis.
Zhang et al. · The neurologist
Added to ASH registry: 2026-05-28
Met343Val mutation disrupts the shuttling of Trp380 leading to a low-activity conformer of activated protein C and causes thrombosis.
Zhou et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Milvexian vs apixaban for stroke prevention in atrial fibrillation: The LIBREXIA atrial fibrillation trial rationale and design
Jain et al. · American heart journal
Added to ASH registry: 2026-05-28
Milvexian, a novel factor XIa inhibitor for stroke prevention: pharmacokinetic and pharmacodynamic evaluation
Mar et al. · Expert opinion on drug metabolism & toxicology
Added to ASH registry: 2026-05-28
Milvexian: An Oral, Bioavailable Factor XIa Inhibitor
Parsa et al. · Cardiology and therapy
Added to ASH registry: 2026-05-28
Milvexian: evaluating the factor XIa inhibitor for the treatment of acute coronary syndrome
Tantry et al. · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-28
Molecular Epidemiological Characteristics of Carbapenem Resistantfrom Hospital Wastewater.
Zhang Q et al. · Infection and drug resistance
Added to ASH registry: 2026-05-28
Multidrug-Resistant Bacteria in Aquaculture Systems in Accra, Ghana
Dayie et al. · Environmental health insights
Added to ASH registry: 2026-05-28
Obstetric antiphospholipid syndrome.
Soto-Peleteiro et al. · Medicina clinica
Added to ASH registry: 2026-05-28
OCEANIC-AF and the inferior efficacy of asundexian compared to apixaban in patients at high risk with atrial fibrillation: Have we come to the end of the road for factor XIa inhibitors?
Ferdinand et al. · American heart journal plus : cardiology research and practice
Added to ASH registry: 2026-05-28
Optimization of laboratory diagnosis of heparin-induced thrombocytopenia using HemosIL-AcuStar-HIT-IgG assay.
Tucker et al. · Laboratory medicine
Added to ASH registry: 2026-05-28
Performance evaluation of heparin-induced platelet aggregation vs serotonin release assay.
Barouqa et al. · American journal of clinical pathology
Added to ASH registry: 2026-05-28
Perioperative Management of Patients Taking Direct Oral Anticoagulants: A Review.
Douketis et al. · JAMA
Added to ASH registry: 2026-05-28
Pharmacokinetics and pharmacodynamics of drug‒drug interactions in hospitalized older adults treated with direct oral anticoagulants.
Decaix T et al. · Aging clinical and experimental research
Added to ASH registry: 2026-05-28
Pharmacokinetics and pharmacodynamics of the factor XIa-inhibiting antibody osocimab in healthy male East Asian volunteers: Results from two phase 1 studies
Dong et al. · Pharmacology research & perspectives
Added to ASH registry: 2026-05-28
Pharmacokinetics of asundexian with combined CYP3A and P-gp inhibitors and an inducer: Target in vitro and in vivo studies
Kanefendt et al. · British journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Pharmacokinetics, pharmacodynamics, and safety of asundexian in healthy Chinese and Japanese volunteers, and comparison with Caucasian data
Chen et al. · Clinical and translational science
Added to ASH registry: 2026-05-28
Pharmacokinetics, pharmacodynamics, and safety of fesomersen, a novel antisense inhibitor of factor XI, in healthy Chinese, Japanese, and Caucasian volunteers
Liu et al. · Clinical and translational science
Added to ASH registry: 2026-05-28
Prevention of Stroke in Intracerebral Haemorrhage Survivors with Atrial Fibrillation: Rationale and Design for PRESTIGE-AF Trial.
Korompoki et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Prothrombin complex concentrate for direct factor Xa inhibitor-associated bleeding or before urgent surgery
Shaw et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Quantifying Residual Rivaroxaban Plasma Concentration after Antagonization with Andexanet Alfa: A Difficult Task in Routine Clinical Practice
Mair et al. · Hamostaseologie
Added to ASH registry: 2026-05-28
Real-world experience with edoxaban for anticoagulation in children at risk for coronary artery thrombosis
Sagiv et al. · Cardiology in the young
Added to ASH registry: 2026-05-28
Reevaluating the role of heparin during mechanical thrombectomy for acute ischemic stroke: Increased risks without functional benefit.
Jazayeri et al. · Clinical neurology and neurosurgery
Added to ASH registry: 2026-05-28
Reversal and resumption of anticoagulants in patients with anticoagulant-associated intracerebral hemorrhage.
Yang et al. · European journal of medical research
Added to ASH registry: 2026-05-28
Reversal of direct oral anticoagulants: guidance from the SSC of the ISTH.
Levy et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Rivaroxaban for stroke patients with antiphospholipid syndrome (RISAPS): protocol for a randomized controlled, phase IIb proof-of-principle trial.
Mittal P et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Rivaroxaban for Venous Thrombosis in a Patient with Congenital Antithrombin Deficiency
Takeuchi et al. · International heart journal
Added to ASH registry: 2026-05-28
Safety and efficacy of factor XIa inhibition with milvexian for secondary stroke prevention (AXIOMATIC-SSP): a phase 2, international, randomised, double-blind, placebo-controlled, dose-finding trial
Sharma et al. · The Lancet. Neurology
Added to ASH registry: 2026-05-28
Safety profile of drugs used in non-cystic fibrosis bronchiectasis: a narrative review
Upadhyay et al. · Therapeutic advances in drug safety
Added to ASH registry: 2026-05-28
Safety, tolerability, pharmacokinetics and pharmacodynamics of milvexian with aspirin and/or clopidogrel in healthy participants
Perera et al. · Scientific reports
Added to ASH registry: 2026-05-28
Scaling theory of fibrin polymerization.
Panyukov · Physical review. E
Added to ASH registry: 2026-05-28
Selective factor XI/XIa inhibitors: a beacon of hope in anticoagulation therapy
Xie et al. · Future medicinal chemistry
Added to ASH registry: 2026-05-28
Sepsis-induced coagulopathy (SIC) in the management of sepsis.
Iba et al. · Annals of intensive care
Added to ASH registry: 2026-05-28
Sepsis-Induced Coagulopathy: A Comprehensive Narrative Review of Pathophysiology, Clinical Presentation, Diagnosis, and Management Strategies.
Williams et al. · Anesthesia and analgesia
Added to ASH registry: 2026-05-28
Short term outcome of neonatal venous thromboembolism in anticoagulated versus observed patients.
Beg KA et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Splanchnic vein thrombosis: management for the thrombosis specialist.
Barnum et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Stroke Prevention in Atrial Fibrillation: Our Current Failures and Required Research
Gurol et al. · Stroke
Added to ASH registry: 2026-05-28
Tackling a deadly global phenomenon: sepsis induced coagulopathy: A narrative review.
Arshad et al. · JPMA. The Journal of the Pakistan Medical Association
Added to ASH registry: 2026-05-28
Targeting tissue factor pathway inhibitor with concizumab to improve hemostasis in patients with Glanzmann thrombasthenia: an in vitro study.
Dubut et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial.
Muir KW et al. · The Lancet. Neurology
Added to ASH registry: 2026-05-28
Tenecteplase vs Alteplase for Patients With Acute Ischemic Stroke: The ORIGINAL Randomized Clinical Trial.
Meng X et al. · JAMA
Added to ASH registry: 2026-05-28
The changing face of cerebral venous sinus thrombosis-emerging new causes and treatments.
Dix et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
The effect of hypotonic pharmacologic lipodissolution on abdominal free flap perfusion: a case report
Seo et al. · Gland surgery
Added to ASH registry: 2026-05-28
The efficacy and safety of direct oral anticoagulants in the treatment of the acute phase of heparin-induced thrombocytopenia: A systematic review.
Sadowski et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
The factor XI/XIa antibody abelacimab combined with enoxaparin inhibits filter clotting in hemodialysis circuits ex vivo
Grafeneder et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
The impact of OCEANIC-AF and the future of factor XIa inhibitors
Palaiodimou et al. · Med (New York, N.Y.)
Added to ASH registry: 2026-05-28
The management of splanchnic vein thrombosis in acute pancreatitis: a global DELPHI consensus study.
Scott et al. · HPB : the official journal of the International Hepato Pancreato Biliary Association
Added to ASH registry: 2026-05-28
The pharmacokinetics of dabigatran in a rat model of hyperlipidaemia induced by poloxamer 407
Kim et al. · Xenobiotica; the fate of foreign compounds in biological systems
Added to ASH registry: 2026-05-28
The Post-Left Atrial Appendage Occlusion Antithrombotic Selection Conundrum: Are We There Yet?
Katapadi A et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
The third-generation anticoagulants: factors XI, XII, and XIII inhibitors
Prajapathi et al. · The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology
Added to ASH registry: 2026-05-28
The Use of Apixaban for Postoperative Venous Thromboembolism Prophylaxis in Gynecologic Cancer
Knisely et al. · Annals of surgical oncology
Added to ASH registry: 2026-05-28
Therapeutic Potential of FXI Inhibitors: Hype or Hope?
Galli et al. · Drugs
Added to ASH registry: 2026-05-28
Thrombotic antiphospholipid syndrome: From guidelines to clinical management.
Paredes-Ruiz et al. · Medicina clinica
Added to ASH registry: 2026-05-28
Ticagrelor vs clopidogrel when coadministered with bivalirudin in patients with acute coronary syndrome undergoing percutaneous coronary intervention
Li et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Treatment of Cutaneous Leishmaniasis lesion caused by Leishmania major Using Leech Therapy in BALB/c Mice.
Shirani-Bidabadi · Journal of vector borne diseases
Added to ASH registry: 2026-05-28
Type 2N von Willebrand disease: genotype drives different bleeding phenotypes and treatment needs.
Daniel MY et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Use of Andexanet Alfa for Factor Xa Inhibitor Reversal in US Verified Trauma Centers: A National Survey.
Fasanya et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Use of protease substrate specificity screening in the rational design of selective protease inhibitors with unnatural amino acids: Application to HGFA, matriptase, and hepsin.
Mahoney MW et al. · Protein science : a publication of the Protein Society
Added to ASH registry: 2026-05-28
When Direct Oral Anticoagulants Should Not Be Standard Treatment: JACC State-of-the-Art Review.
Bejjani et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
A Bioinspired and Cost-Effective Device for Minimally Invasive Blood Sampling
Zoratto N et al. · Advanced science
Added to ASH registry: 2026-05-27
A reevaluation and redescription of the branchiobdellidan Sathodrilus tetrodonta (Pierantoni, 1906) new comb. (Annelida: Clitellata)
Gelder SR · Zootaxa
Added to ASH registry: 2026-05-27
Anticoagulation Monitoring and Targets: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation Collaborative Consensus Conference
Ozment CP et al. · Pediatric critical care medicine
Added to ASH registry: 2026-05-27
Antithrombotic therapy in patients with complex percutaneous coronary intervention
Larrubia Valle et al. · Interventional cardiology clinics
Added to ASH registry: 2026-05-27
Aptameric hirudins as selective and reversible EXosite-ACTive site (EXACT) inhibitors
Yu HC et al. · Nature communications
Added to ASH registry: 2026-05-27
Biology, morphology and taxonomy of a snail-feeding leech from North Carolina USA, provisionally identified as Helobdella lineata (Verrill, 1874) (Glossiphoniidae): First evidence for extra-oral digestion in the Hirudinea
Sawyer RT et al. · Zootaxa
Added to ASH registry: 2026-05-27
Biomimetic nanoparticles co-deliver hirudin and lumbrukinase to ameliorate thrombus and inflammation for atherosclerosis therapy
Cheng M et al. · Asian journal of pharmaceutical sciences
Added to ASH registry: 2026-05-27
Bivalirudin as a substitute for heparin in neurointervention for patients with heparin-induced thrombocytopenia
Sukumaran M et al. · Journal of stroke and cerebrovascular diseases
Added to ASH registry: 2026-05-27
Bivalirudin as an anticoagulation strategy for acute hemodialysis in children: Two cases with a summary of recent literature
Viaene LV et al. · Hemodialysis international
Added to ASH registry: 2026-05-27
Bivalirudin in Extracorporeal Membrane Oxygenation
Dunham S et al. · Journal of cardiovascular pharmacology
Added to ASH registry: 2026-05-27
Bivalirudin Monitoring in Pediatric Ventricular Assist Device and Extracorporeal Membrane Oxygenation: Analysis of Single-Center Retrospective Cohort Data 2018-2022
Engel ER et al. · Pediatric Critical Care Medicine
Added to ASH registry: 2026-05-27
Bivalirudin versus heparin in patients with or without bail-out GPI use: a pre-specified subgroup analysis
Liao et al. · BMC medicine
Added to ASH registry: 2026-05-27
Bivalirudin versus heparin in ST and non-ST-segment elevation myocardial infarction
Omerovic et al. · Cardiovascular revascularization medicine
Added to ASH registry: 2026-05-27
Bivalirudin versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
Sun B et al. · Cardiovascular drugs and therapy
Added to ASH registry: 2026-05-27
Bivalirudin vs heparin anticoagulation in STEMI: confirmation of the BRIGHT-4 results
Stone GW · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-27
Bolus-only bivalirudin for carotid endarterectomy in a patient with heparin-induced thrombocytopenia
Venema R et al. · Canadian journal of anaesthesia
Added to ASH registry: 2026-05-27
Characterization of active peptides derived from three leeches and comparison of their anti-thrombotic mechanisms using the tail vein thrombosis model in mice and metabonomics
Dong Y et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-27
Combined drug anti-deep vein thrombosis therapy based on platelet membrane biomimetic targeting nanotechnology
Xiao H et al. · Biomaterials
Added to ASH registry: 2026-05-27
Comparison of Outcomes in Patients Requiring Mechanical Circulatory Support Who Received Cangrelor in Addition to Anticoagulation Versus Anticoagulation Alone
Martin TC et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
Comparison of short-to-medium-term ischemia and bleeding risks between unfractionated heparin and bivalirudin
Hou et al. · Zhonghua yi xue za zhi
Added to ASH registry: 2026-05-27
Comparison of the effects on coagulation function and safety of bivalirudin and heparin
Wang et al. · Medicine
Added to ASH registry: 2026-05-27
Differential use of glycoprotein IIb/IIIa inhibitors with bivalirudin in patients with STEMI undergoing PCI
Mushahid H et al. · American journal of cardiovascular drugs
Added to ASH registry: 2026-05-27
Efficacy and potential mechanism of atherosclerosis prevention by the active components of leech based on network pharmacology
Lv Q et al. · Heliyon
Added to ASH registry: 2026-05-27
Evaluation of hemostatic, anti-inflammatory, wound healing, skin irritation and acute toxicity of leech (Hirudo nipponia) extract
Li et al. · Journal of ethnopharmacology
Added to ASH registry: 2026-05-27
Evolution of treatment for unspecific back pain: From past to future
Herrera B et al. · La Tunisie medicale
Added to ASH registry: 2026-05-27
Heparin and bivalirudin in percutaneous coronary intervention for acute coronary syndrome
Wang et al. · Cardiovascular therapeutics
Added to ASH registry: 2026-05-27
Heparin-induced DRESS syndrome in a paediatric patient and successful anaesthetic management in cardiovascular bypass surgery: case report
Pea-Blanco L et al. · Journal of cardiothoracic surgery
Added to ASH registry: 2026-05-27
Hirudin delays the progression of diabetic kidney disease by inhibiting glomerular endothelial cell migration and abnormal angiogenesis
Zhang J et al. · Biomedicine & pharmacotherapy
Added to ASH registry: 2026-05-27
Hirudin in the Treatment of Chronic Kidney Disease
Liu SJ et al. · Molecules
Added to ASH registry: 2026-05-27
Impact of inflammation and steroids on anti-coagulation in children supported on a ventricular assist device
Brandewie K et al. · Journal of Artificial Organs
Added to ASH registry: 2026-05-27
Improving Mechanical Circulatory Support Outcomes in Failing Bidirectional Glenn Physiology
Kobayashi RL et al. · Pediatric Cardiology
Added to ASH registry: 2026-05-27
Intravenous Direct Thrombin Inhibitors for Acute Venous Thromboembolism or Heparin-Induced Thrombocytopenia with Thrombosis in Children: A Systematic Review
Kiskaddon AL et al. · Seminars in Thrombosis and Hemostasis
Added to ASH registry: 2026-05-27
Intravenous Direct Thrombin Inhibitors for Acute Venous Thromboembolism or Heparin-Induced Thrombocytopenia with Thrombosis in Children: A Systematic Review of the Literature
Kiskaddon AL et al. · Semin Thromb Hemost
Added to ASH registry: 2026-05-27
Leech extract alleviates idiopathic pulmonary fibrosis by TGF-β1/Smad3 signaling pathway
Zhang Y et al. · Journal of ethnopharmacology
Added to ASH registry: 2026-05-27
Monitoring Breast Reconstruction Flaps Using Near-Infrared Spectroscopy Tissue Oximetry
Kumbasar DE et al. · Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses
Added to ASH registry: 2026-05-27
New anticoagulant protein from medicinal leech
Manuvera VA et al. · Biochemical and biophysical research communications
Added to ASH registry: 2026-05-27
Optimizing outcomes in ST-segment elevation myocardial infarction: is prolonged bivalirudin infusion the answer?
Cavender et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-27
Postprocedural anticoagulation after primary percutaneous coronary intervention for ST-segment-elevation myocardial infarction with bivalirudin
Yan et al. · Circulation
Added to ASH registry: 2026-05-27
Prospective randomized pilot study comparing bivalirudin versus heparin in neonatal and pediatric extracorporeal membrane oxygenation
McMichael A et al. · Pediatric critical care medicine
Added to ASH registry: 2026-05-27
Recombinant hirudin attenuates pulmonary hypertension and thrombosis in acute pulmonary embolism rat model
Wei X et al. · PeerJ
Added to ASH registry: 2026-05-27
Recombinant hirudin suppresses angiogenesis of diffuselarge B-cell lymphoma through regulation of the PAR-1-VEGF
Zhao J et al. · Chemical biology & drug design
Added to ASH registry: 2026-05-27
Recombinant neorudin and its active metabolite hirudin: the fate of a novel anticoagulant drug
Li Q et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-27
Reduced-dose of bivalirudin (without the post-procedure infusion) in patients with acute coronary syndrome undergoing elective percutaneous coronary intervention
Wang Q et al. · BMC cardiovascular disorders
Added to ASH registry: 2026-05-27
Research progress on the treatment of diabetic nephropathy with leech and its active ingredients
Tian F et al. · Frontiers in endocrinology
Added to ASH registry: 2026-05-27
Revisiting the effect of cholesteryl sulfate on clotting and fibrinolysis: Inhibition of human thrombin and other human blood proteases
Al-Horani RA · Heliyon
Added to ASH registry: 2026-05-27
Revisiting the efficacy and safety of bivalirudin in patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention
Maqsood MH et al. · Catheterization and cardiovascular interventions
Added to ASH registry: 2026-05-27
Risk factors for thromboembolic events in pediatric patients with ventricular assist devices
Adderley J et al. · JTCVS open
Added to ASH registry: 2026-05-27
Risk factors for thromboembolic events in pediatric patients with ventricular assist devices
Adderley J et al. · JTCVS Open
Added to ASH registry: 2026-05-27
Safety, tolerability, pharmacodynamics, and pharmacokinetics of recombinant Neorudin, a new anticoagulant drug, in patients undergoing coronary angiography
Liu YB et al. · Clinical pharmacology in drug development
Added to ASH registry: 2026-05-27
The effect and mechanism of freeze-dried powder ofon improving inflammatory injury of rat glomerular mesangial cells through TXNIP / NLRP3 pathway
Sun X et al. · Heliyon
Added to ASH registry: 2026-05-27
Therapeutic Potentials of Medicinal Leech in Chinese Medicine
Wu S et al. · American Journal of Chinese Medicine
Added to ASH registry: 2026-05-27
Vasospastic angina: a review on diagnostic approach and management
Jenkins et al. · Therapeutic advances in cardiovascular disease
Added to ASH registry: 2026-05-27
Leech protein extract ameliorated hyperuricemia by restoring gut microbiota dysregulation and affecting serum metabolites
Liu X, Liang XQ, Lu TC et al. · World journal of gastroenterology
Added to ASH registry: 2026-05-26
The High-Affinity Chymotrypsin Inhibitor Eglin C Poorly Inhibits Human Chymotrypsin-Like Protease: Gln192 and Lys218 Are Key Determinants
Németh BZ, Kiss B, Sahin-Tóth M, Magyar C, Pál G · Proteins
Added to ASH registry: 2026-05-26
Hirudin enhances perforator flap survival: Clinical application report and mechanistic exploration
Wei D et al. · Journal of stomatology, oral and maxillofacial surgery
Added to ASH registry: 2026-03-18
Investigation of oxidant-antioxidant status in patients treated with hirudotherapy: an experimental study
Sarikan I, Savas H · JPMA. The Journal of the Pakistan Medical Association
Added to ASH registry: 2026-03-18
New anticoagulant protein from medicinal leech
Manuvera V et al. · Biochemical and biophysical research communications
Added to ASH registry: 2026-03-18
Therapeutic Potentials of Medicinal Leech in Chinese Medicine
Wu S et al. · The American journal of Chinese medicine
Added to ASH registry: 2026-03-18
Transcriptomic profiling and the first spatial expression analysis of candidate genes in the salivary gland of the East Asian medicinal leech, Hirudo nipponia
Kim J et al. · Developmental and comparative immunology
Added to ASH registry: 2026-03-18
Tyrosine phosphorylation of recombinant hirudin increases affinity to thrombin and antithrombotic activity
Volkova A, Semenyuk P · Proteins
Added to ASH registry: 2026-03-18
2023
201 articlesA BRIGHT outlook for bivalirudin in patients with ST-segment elevation myocardial infarction
Vergallo et al. · European heart journal
Added to ASH registry: 2026-05-29
Analysis of Wholesale Drug Acquisition and Laboratory Assessment Costs Between Heparin Compared With Bivalirudin-Based Systemic Anticoagulation Strategies in Adult Extracorporeal Membrane Oxygenation
Seelhammer et al. · Critical care medicine
Added to ASH registry: 2026-05-29
Anti-thrombotic Therapy With Cangrelor and Bivalirudin in Venoarterial Extracorporeal Membrane Oxygenation Patients Undergoing Percutaneous Coronary Intervention: A Single-Center Experience
Baldetti et al. · ASAIO journal (American Society for Artificial Internal Organs : 1992)
Added to ASH registry: 2026-05-29
Anticoagulation Stability With Bivalirudin: Positioning the Horse Before the Cart
Chen et al. · ASAIO journal (American Society for Artificial Internal Organs : 1992)
Added to ASH registry: 2026-05-29
Apixaban at Apex? Aligning Drug Pricing With Value in Cancer-Associated Thrombosis
Ito et al. · Annals of internal medicine
Added to ASH registry: 2026-05-29
Bivalirudin Compared to Heparin as the Primary Anticoagulant in Pediatric Berlin Heart Recipients
Freniere et al. · ASAIO journal (American Society for Artificial Internal Organs : 1992)
Added to ASH registry: 2026-05-29
Bivalirudin Superiority in Pediatric Berlin Hearts: Too Early to Draw Conclusions?
Seelhammer et al. · ASAIO journal (American Society for Artificial Internal Organs : 1992)
Added to ASH registry: 2026-05-29
Comparison of bivalirudin versus heparin in adult extracorporeal membrane oxygenation anticoagulant therapy: A retrospective case-control study
Tong et al. · The International journal of artificial organs
Added to ASH registry: 2026-05-29
Editorial: Bivalirudin with post-procedural infusion: Should the Guidelines change to keep up with the data?
Lipinski · Cardiovascular revascularization medicine : including molecular interventions
Added to ASH registry: 2026-05-29
Functionalization of PCL-based nanofibers loaded with hirudin as blood contact materials
Zheng et al. · Biomaterials advances
Added to ASH registry: 2026-05-29
Impact of Bivalirudin on Patients with Acute Coronary Syndrome Undergoing Rotational Atherectomy in Real-Life Setting: A Retrospective Cohort Study
Li et al. · Anatolian journal of cardiology
Added to ASH registry: 2026-05-29
One-year clinical outcomes of bivalirudin versus unfractionated heparin in patients with type 2 diabetes undergoing elective percutaneous coronary intervention
Li et al. · Diabetes & metabolic syndrome
Added to ASH registry: 2026-05-29
One-Year Safety and Effectiveness of Bivalirudin versus Heparin in Patients Undergoing Elective Percutaneous Coronary Intervention
Li et al. · Reviews in cardiovascular medicine
Added to ASH registry: 2026-05-29
Pharmacokinetic drug-drug interactions with direct anticoagulants in the management of cancer-associated thrombosis
Van et al. · British journal of clinical pharmacology
Added to ASH registry: 2026-05-29
The effect of bivalirudin on coagulation function in male patients with coronary heart disease undergoing percutaneous coronary intervention
Dequan et al. · Pakistan journal of pharmaceutical sciences
Added to ASH registry: 2026-05-29
Use of Bivalirudin for Chronic Total Occlusion Percutaneous Intervention: Insights From the PROGRESS-CTO Registry
Verreault-Julien et al. · The Journal of invasive cardiology
Added to ASH registry: 2026-05-29
Use of ecarin chromogenic assay during bivalirudin anticoagulation in adult extracorporeal membrane oxygenation
Krauter et al. · Thrombosis research
Added to ASH registry: 2026-05-29
30-Day Post-Discharge Prophylaxis with Rivaroxaban Prevents Porto-mesenteric Venous Thrombosis Following Laparoscopic Sleeve Gastrectomy
Swartz et al. · Obesity surgery
Added to ASH registry: 2026-05-28
6-(Arylaminomethyl) Isoquinolines as Enzyme Inhibitors and Their Preparation: A Patent Highlight of Factor XIIa Inhibitors
Al-Horani et al. · Cardiovascular & hematological agents in medicinal chemistry
Added to ASH registry: 2026-05-28
A bispecific antibody NXT007 exerts a hemostatic activity in hemophilia A monkeys enough to keep a nonhemophilic state.
Teranishi-Ikawa Y et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism
Andersen et al. · Blood
Added to ASH registry: 2026-05-28
A global comparative field study to evaluate the factor VIII activity of efanesoctocog alfa by one-stage clotting and chromogenic substrate assays at clinical haemostasis laboratories.
Pipe et al. · Haemophilia : the official journal of the World Federation of Hemophilia
Added to ASH registry: 2026-05-28
A new strategy for anticoagulation: The factor XI inhibitors
Vedovati et al. · European journal of internal medicine
Added to ASH registry: 2026-05-28
A Non-competitive Serpin-Like Thrombin Inhibitor Isolated from Moringa oleifera Exhibit a High Affinity for Thrombin
Sawetaji et al. · The protein journal
Added to ASH registry: 2026-05-28
A Retrospective Review of Four-Factor Prothrombin Complex Concentrate for Factor Xa Inhibitor-Related Bleedings
Hitchcock et al. · Journal of pharmacy practice
Added to ASH registry: 2026-05-28
Abelacimab in Cancer-Associated Thrombosis: The Right Drug at the Right Time for the Right Purpose. A Comprehensive Review.
Fioretti AM et al. · Reviews in cardiovascular medicine
Added to ASH registry: 2026-05-28
Acute pulmonary embolism: Diagnosis and management.
Khandait et al. · Indian heart journal
Added to ASH registry: 2026-05-28
Adherence to protocols for the use of reversal agents in patients treated with direct oral anticoagulants
Mitrovic et al. · Current medical research and opinion
Added to ASH registry: 2026-05-28
Adjunctive technologies in postoperative free-flap monitoring: a systematic review
Lacey H et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Added to ASH registry: 2026-05-28
Anticoagulant therapies against sepsis-induced disseminated intravascular coagulation.
Umemura et al. · Acute medicine & surgery
Added to ASH registry: 2026-05-28
Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes
Hsu et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes
Adabag et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes. Reply
Kirchhof et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Antiphospholipid syndrome management: a 2023 update and practical algorithm-based approach.
Ambati et al. · Current opinion in rheumatology
Added to ASH registry: 2026-05-28
Antiphospholipid syndrome, antiphospholipid antibodies, and stroke.
Mittal et al. · International journal of stroke : official journal of the International Stroke Society
Added to ASH registry: 2026-05-28
Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management.
Knight et al. · BMJ (Clinical research ed.)
Added to ASH registry: 2026-05-28
Antithrombotic Effects of the Novel Small-Molecule Factor XIa Inhibitor Milvexian in a Rabbit Arteriovenous Shunt Model of Venous Thrombosis
Wang et al. · TH open : companion journal to thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Apixaban and Rivaroxaban Anti-Xa Concentration Utilization in Clinical Practice
Kim et al. · Journal of cardiovascular pharmacology
Added to ASH registry: 2026-05-28
Apixaban for Prevention of Thromboembolism in Pediatric Heart Disease.
Payne et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
Apixaban for Treatment of Atrial Fibrillation and Venous Thromboembolism After Lung Transplantation
Nikodem et al. · Progress in transplantation (Aliso Viejo, Calif.)
Added to ASH registry: 2026-05-28
Apixaban versus no anticoagulation for the prevention of venous thromboembolism in children with newly diagnosed acute lymphoblastic leukaemia or lymphoma (PREVAPIX-ALL): a phase 3, open-label, randomised, controlled trial.
O'Brien et al. · The Lancet. Haematology
Added to ASH registry: 2026-05-28
Aptamer-thrombin loaded magnetic microspheres for bio-specific extraction and precise detection of hirudin
Cao X et al. · Talanta
Added to ASH registry: 2026-05-28
Assays to Monitor Bivalirudin
Davidson. · Methods in molecular biology (Clifton, N.J.)
Added to ASH registry: 2026-05-28
Assessment of Platelet Function by Automated Light Transmission Aggregometry.
Sarkar et al. · Methods in molecular biology (Clifton, N.J.)
Added to ASH registry: 2026-05-28
Assessment of Platelet Function by High-Throughput Screening Light Transmission Aggregometry: Optimul Assay.
Chan et al. · Methods in molecular biology (Clifton, N.J.)
Added to ASH registry: 2026-05-28
Autoimmune Heparin-Induced Thrombocytopenia
Warkentin TE · Journal of clinical medicine
Added to ASH registry: 2026-05-28
Bivalirudin versus unfractionated heparin in patients with myocardial infarction undergoing percutaneous coronary intervention: A systematic review and meta-analysis of randomized controlled trials.
Al-Abdouh A et al. · Cardiovascular revascularization medicine : including molecular interventions
Added to ASH registry: 2026-05-28
Cancer-associated thrombosis: enhanced awareness and pathophysiologic complexity.
Falanga et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Catheter-Directed Thrombolysis for Deep Vein Thrombosis: Serving at Break Point.
Barnes GD et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Catheter-Directed Thrombolysis Protocols for Deep Venous Thrombosis of the Lower Extremities-A Systematic Review and Meta-analysis.
Duarte-Gamas L et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Chromogenic and Clot-Based Bivalirudin Assays for Monitoring Anticoagulation
Raghavendran et al. · The journal of applied laboratory medicine
Added to ASH registry: 2026-05-28
Clinical Outcomes of Anticoagulated Patients With Atrial Fibrillation After Falls or Head Injury: Insights From RE-LY.
Caldeira et al. · Stroke
Added to ASH registry: 2026-05-28
Comparative Efficacy and Safety of Thrombolytic Agents for Pulmonary Embolism: A Bayesian Network Meta-Analysis.
Li H et al. · Pharmacology
Added to ASH registry: 2026-05-28
Comparison of Bivalirudin Versus Heparin for Anticoagulation During Extracorporeal Membrane Oxygenation
Hasegawa et al. · ASAIO journal (American Society for Artificial Internal Organs : 1992)
Added to ASH registry: 2026-05-28
Concomitant Left Atrial Appendage Occlusion and Transcatheter Aortic Valve Replacement Among Patients With Atrial Fibrillation.
Kapadia SR et al. · Circulation
Added to ASH registry: 2026-05-28
Correlation between partial thromboplastin time and thromboelastography in adult critically ill patients requiring bivalirudin for extracorporeal membrane oxygenation
Buckley et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Cost-effectiveness of bivalirudin in pediatric ventricular assist devices
Burstein et al. · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Added to ASH registry: 2026-05-28
Coumarins as factor XIIa inhibitors: Potency and selectivity improvements using a fragment-based strategy
Davoine et al. · European journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Cryo-EM structure of coagulation factor V short.
Mohammed et al. · Blood
Added to ASH registry: 2026-05-28
Dabigatran etexilate is efficacious in consumptive coagulopathy and pain associated with venous malformations
Liu et al. · Journal of vascular surgery. Venous and lymphatic disorders
Added to ASH registry: 2026-05-28
Dabigatran-reversal failure using standard dose of idarucizumab: a systematic review and meta-analysis of cases
Melicine et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Design and Preclinical Characterization Program toward Asundexian (BAY 2433334), an Oral Factor XIa Inhibitor for the Prevention and Treatment of Thromboembolic Disorders
Roehrig et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Determination of the Potential Clinical Benefits of Small Molecule Factor XIa Inhibitors in Arterial Thrombosis
Wichaiyo et al. · ACS pharmacology & translational science
Added to ASH registry: 2026-05-28
Development of new anticoagulant in 2023: Prime time for anti-factor XI and XIa inhibitors
Bentounes et al. · Journal de medecine vasculaire
Added to ASH registry: 2026-05-28
Diagnosis and laboratory monitoring of acquired hemophilia A.
Platton et al. · Hematology. American Society of Hematology. Education Program
Added to ASH registry: 2026-05-28
Direct Oral Anticoagulants for Stroke Prevention in Patients With Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials.
McIntyre et al. · Circulation
Added to ASH registry: 2026-05-28
Discovery and development of Factor Xa inhibitors (2015-2022)
Zheng et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-28
Early high-dose intravenous immunoglobulin for refractory heparin-induced thrombocytopenia with stroke: Two case reports
Makita et al. · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Added to ASH registry: 2026-05-28
Edoxaban for 12 Months Versus 3 Months in Patients With Cancer With Isolated Distal Deep Vein Thrombosis (ONCO DVT Study): An Open-Label, Multicenter, Randomized Clinical Trial
Yamashita et al. · Circulation
Added to ASH registry: 2026-05-28
Edoxaban Versus Low-Molecular-Weight Heparin in Hospitalized COVID-19 Patients With Atrial Fibrillation
Olivera et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Effect of Anticoagulant Versus Non-Anticoagulant Therapy on Mortality of Sepsis-Induced Disseminated Intravascular Coagulation: A Systematic Review and Meta-Analysis.
Qi et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Effect of PCC on Thrombin Generation among Patients on Factor Xa Inhibitors with Major Bleeding or Needing Urgent Surgery (GAUGE): Design and Rationale
Shaw et al. · TH open : companion journal to thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Effectiveness and safety of catheter-directed thrombolysis in conjunction with percutaneous mechanical thrombectomy for acute iliofemoral deep vein thrombosis: A meta-analysis.
Li W et al. · Journal of vascular surgery. Venous and lymphatic disorders
Added to ASH registry: 2026-05-28
Effectiveness and Safety of Dabigatran Reversal with Idarucizumab in the Taiwanese Population: A Comparison Based on Eligibility for Inclusion in Clinical Trials.
Dai et al. · Medicina (Kaunas, Lithuania)
Added to ASH registry: 2026-05-28
Efficacy and Safety of Apixaban versus Dalteparin as a Treatment for Cancer-Associated Venous Thromboembolism: A Systematic Review and Meta-Analysis
Arce-Huamani et al. · Medicina (Kaunas, Lithuania)
Added to ASH registry: 2026-05-28
Efficacy and safety of edoxaban in patients early after surgical bioprosthetic valve implantation or valve repair: A randomized clinical trial
Shim et al. · The Journal of thoracic and cardiovascular surgery
Added to ASH registry: 2026-05-28
Efficacy and safety of garadacimab, a factor XIIa inhibitor for hereditary angioedema prevention (VANGUARD): a global, multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
Craig et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
Evaluation and Management of Chronic Thromboembolic Pulmonary Hypertension.
Yang J et al. · Chest
Added to ASH registry: 2026-05-28
Evaluation of mechanical thrombectomy in acute ischemic stroke related to a distal arterial occlusion: A randomized controlled trial.
Clarençon F et al. · International journal of stroke : official journal of the International Stroke Society
Added to ASH registry: 2026-05-28
Experimentally Validated Novel Factor XIIa Inhibitors Identified by Docking and Quantum Chemical Post-processing
Ilin et al. · Molecular informatics
Added to ASH registry: 2026-05-28
Factor XI inhibitors for the prevention of cardiovascular disease: A new therapeutic approach on the horizon?
Santagata et al. · Blood reviews
Added to ASH registry: 2026-05-28
Factor XI Inhibitors in Early Clinical Trials: A Meta-analysis
Galli et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Factor XI Inhibitors: Potential Role in End-Stage Kidney Disease
Ades et al. · Seminars in nephrology
Added to ASH registry: 2026-05-28
Factor XIa Inhibitors as a Novel Anticoagulation Target: Recent Clinical Research Advances
Xia et al. · Pharmaceuticals (Basel, Switzerland)
Added to ASH registry: 2026-05-28
Factor XIa Inhibitors in Anticoagulation Therapy: Recent Advances and Perspectives
Xie et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Final Study Report of Andexanet Alfa for Major Bleeding With Factor Xa Inhibitors.
Milling et al. · Circulation
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia after switching from unfractionated heparin to low-molecular-weight heparin: A case report and literature review
Zhang et al. · Clinical nephrology
Added to ASH registry: 2026-05-28
Idarucizumab for dabigatran reversal: A systematic review and meta-analysis of indications and outcomes.
van et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Idarucizumab for Emergency Reversal of the Anticoagulant Effects of Dabigatran: Final Results of a Japanese Postmarketing Surveillance Study
Yasaka et al. · Cardiology and therapy
Added to ASH registry: 2026-05-28
Identification and characterization of a novel 6'-N-aminoglycoside acetyltransferase AAC(6')-Va from a clinical isolate of.
Zhang G et al. · Frontiers in microbiology
Added to ASH registry: 2026-05-28
In Silico and In Vitro Evaluation of Some Amidine Derivatives as Hit Compounds towards Development of Inhibitors against Coronavirus Diseases.
Hassan AHE et al. · Viruses
Added to ASH registry: 2026-05-28
In vitro Effect of Dalteparin and Argatroban on Hemostasis in Critically Ill Sepsis Patients with New-Onset Thrombocytopenia
Nygaard et al. · TH open : companion journal to thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Incidence and risk factors for venous thromboembolism in the Cancer-VTE Registry pancreatic cancer subcohort.
Okusaka et al. · Journal of gastroenterology
Added to ASH registry: 2026-05-28
Incidence of Venous Thromboembolism Among Commonly Prescribed Second-Generation Antipsychotics.
Paulmann et al. · Journal of pharmacy practice
Added to ASH registry: 2026-05-28
Incidence of venous thromboembolism following adrenalectomy: A CESQIP analysis.
Sada et al. · American journal of surgery
Added to ASH registry: 2026-05-28
Interactions Between Direct Oral Anticoagulants (DOACs) and Antiseizure Medications: Potential Implications on DOAC Treatment.
Goldstein R et al. · CNS drugs
Added to ASH registry: 2026-05-28
Investigating Betrixaban Maleate drug degradation profiles, isolation and characterization of unknown degradation products by mass-triggered preparative HPLC, HRMS, and NMR
Surukonti et al. · Journal of pharmaceutical and biomedical analysis
Added to ASH registry: 2026-05-28
Laboratory-guided repeat dosing of idarucizumab for dabigatran reversal
Jones et al. · Clinical toxicology (Philadelphia, Pa.)
Added to ASH registry: 2026-05-28
Long-term survival in venous thromboembolic disease: rivaroxaban vs. warfarin - propensity score matching study
Ramos-Isaza et al. · BMC pharmacology & toxicology
Added to ASH registry: 2026-05-28
Management of splanchnic vein thrombosis.
Elkrief et al. · JHEP reports : innovation in hepatology
Added to ASH registry: 2026-05-28
Mechanical thrombectomy for acute ischemic stroke with large vessel occlusion in pregnancy with mechanical heart valves： A case report.
Zhang et al. · Heliyon
Added to ASH registry: 2026-05-28
Mechanisms and management of the coagulopathy of trauma and sepsis: trauma-induced coagulopathy, sepsis-induced coagulopathy, and disseminated intravascular coagulation.
Iba et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Membrane oxygenator longevity was higher in argatroban-treated patients undergoing vvECMO
Menninger et al. · European journal of clinical investigation
Added to ASH registry: 2026-05-28
Microwave assisted synthesis of fluorescent hetero atom doped carbon dots for determination of betrixaban with greenness evaluation
El-Semary et al. · RSC advances
Added to ASH registry: 2026-05-28
Myeloproliferative neoplasms and splanchnic vein thrombosis: Contemporary diagnostic and therapeutic strategies.
Kiladjian et al. · American journal of hematology
Added to ASH registry: 2026-05-28
New pharmacotherapeutic options for oral anticoagulant treatment in atrial fibrillation patients aged 65 and older: factor XIa inhibitors and beyond
Santostasi et al. · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-28
New Therapeutic Targets for the Prevention and Treatment of Venous Thromboembolism With a Focus on Factor XI Inhibitors
Chan et al. · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-28
News at XI: moving beyond factor Xa inhibitors
Fredenburgh et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Novel Monitoring and Dose Adjustment of Argatroban, a Direct Thrombin Inhibitor, to Maintain Therapeutic Anticoagulation in a Patient With Antiphospholipid Antibody Syndrome, Heparin-Induced Thrombocytopenia, and COVID-19 Pneumonia
Ryan CE et al. · Critical care explorations
Added to ASH registry: 2026-05-28
OKL-1111, A modified cyclodextrin as a potential universal reversal agent for anticoagulants
Meijers et al. · Thrombosis research
Added to ASH registry: 2026-05-28
One case of recurrent ST-segment elevation myocardial infarction in a patient with antiphospholipid syndrome complicated with severe thrombocytopenia within a short period of time: A case report.
Qiu Z et al. · Medicine
Added to ASH registry: 2026-05-28
Oral direct thrombin inhibitors or oral factor Xa inhibitors versus conventional anticoagulants for the treatment of deep vein thrombosis
Wang et al. · The Cochrane database of systematic reviews
Added to ASH registry: 2026-05-28
Oral factor Xa inhibitor underutilization following lower extremity peripheral vascular intervention
Bhuta et al. · Journal of vascular surgery
Added to ASH registry: 2026-05-28
Oral FXIIa inhibitor KV998086 suppresses FXIIa and single chain FXII mediated kallikrein kinin system activation
Clermont et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-28
Outcome after intracranial hemorrhage under dabigatran and reversal with idarucizumab versus under vitamin-K-antagonists - the RIC-ICH study.
Kuklik et al. · Frontiers in neurology
Added to ASH registry: 2026-05-28
Percutaneous Management of High-Risk Pulmonary Embolism.
Carroll et al. · Circulation. Cardiovascular interventions
Added to ASH registry: 2026-05-28
Perioperative Myocardial Infarction Following Dabigatran Reversal With Idarucizumab in a Patient Undergoing Orthotopic Liver Transplantation
Barroso et al. · Cureus
Added to ASH registry: 2026-05-28
Pharmacokinetic and Pharmacodynamic Interactions Between Henagliflozin, a Novel Selective SGLT-2 Inhibitor, and Warfarin in Healthy Chinese Subjects
He et al. · Clinical therapeutics
Added to ASH registry: 2026-05-28
Pharmacology and Clinical Development of Factor XI Inhibitors
Greco et al. · Circulation
Added to ASH registry: 2026-05-28
Platelet function testing and clinical outcomes in peripheral arterial disease: Systematic review and narrative synthesis.
Kankaria et al. · Journal of vascular surgery
Added to ASH registry: 2026-05-28
Prolonged infusion of bivalirudin after elective percutaneous coronary intervention protects against procedural myocardial injury (a COBER study)-a randomized trial.
Wu et al. · Scientific reports
Added to ASH registry: 2026-05-28
Prospection of Peptide Inhibitors of Thrombin from Diverse Origins Using a Machine Learning Pipeline
Balakrishnan N et al. · Bioengineering (Basel, Switzerland)
Added to ASH registry: 2026-05-28
Real world utilization of Andexanet alfa in the management of oral factor Xa inhibitor-associated gastrointestinal bleeding
Brown et al. · The American journal of emergency medicine
Added to ASH registry: 2026-05-28
Real-world clinical outcomes among US Veterans with oral factor xa inhibitor-related major bleeding treated with andexanet alfa or 4-factor prothrombin complex concentrate
Sutton et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Reduced dose direct oral anticoagulants compared with warfarin with high time in therapeutic range in nonvalvular atrial fibrillation
Jansson et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Removing direct oral factor Xa inhibitor interferences from routine and specialised coagulation assays using a raw activated charcoal product
Buckley et al. · Clinica chimica acta; international journal of clinical chemistry
Added to ASH registry: 2026-05-28
Retrospective Analysis of the Real-World Utilization of 4-Factor Prothrombin Complex Concentrate and Plasma in Oral Anticoagulant-Associated Bleeding in US Hospitals.
Refaai et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Reversal agents for current and forthcoming direct oral anticoagulants
van et al. · European heart journal
Added to ASH registry: 2026-05-28
Risk stratification of acute pulmonary embolism.
de Wit et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Role of Infrared Thermography in Planning and Monitoring of Head and Neck Microvascular Flap Reconstruction
Chava SK et al. · Plastic and reconstructive surgery. Global open
Added to ASH registry: 2026-05-28
Safety and efficacy of apixaban versus low-molecular weight heparin or vitamin-K antagonists for venous thromboembolism treatment in patients with severe renal failure: A systematic review and meta-analysis
Almajdi et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation: What We Need to Know and How to Manage for Prolonged Casualty Care.
Nam et al. · Journal of special operations medicine : a peer reviewed journal for SOF medical professionals
Added to ASH registry: 2026-05-28
Sepsis-induced Coagulopathy Subphenotype Identification by Latent Class Analysis.
Cai et al. · Balkan medical journal
Added to ASH registry: 2026-05-28
Stability of Rivaroxaban and Apixaban Anti-Xa Activities in Whole Blood Samples: A French Bicentric Study
Raynor et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Standard operating procedure for idarucizumab reversal of dabigatran anticoagulation in ischemic and hemorrhagic stroke.
Frol et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Study of Rivaroxaban for Cerebral Venous Thrombosis: A Randomized Controlled Feasibility Trial Comparing Anticoagulation With Rivaroxaban to Standard-of-Care in Symptomatic Cerebral Venous Thrombosis
Field et al. · Stroke
Added to ASH registry: 2026-05-28
Tenecteplase versus alteplase in acute ischaemic cerebrovascular events (TRACE-2): a phase 3, multicentre, open-label, randomised controlled, non-inferiority trial.
Wang Y et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
The effects of coagulation factors on the risk of endometriosis: a Mendelian randomization study.
Li et al. · BMC medicine
Added to ASH registry: 2026-05-28
The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation.
Iba et al. · Journal of intensive care
Added to ASH registry: 2026-05-28
The Safety, Pharmacokinetics, and Pharmacodynamics of SHR2285, an Oral Small Molecule Factor XIa Inhibitor, in Healthy Chinese Volunteers
Xu et al. · Clinical drug investigation
Added to ASH registry: 2026-05-28
The Utility of Smartphone-Based Thermal Imaging in the Management and Monitoring of Microvascular Flap Procedures: A Systematic Review and Meta-Analysis
Hudson T et al. · Annals of plastic surgery
Added to ASH registry: 2026-05-28
Thrombolysis after dabigatran reversal: A nation-wide Italian multicentre study, systematic review and meta-analysis
Romoli et al. · European stroke journal
Added to ASH registry: 2026-05-28
Thrombolysis for acute ischaemic stroke: current status and future perspectives.
Tsivgoulis G et al. · The Lancet. Neurology
Added to ASH registry: 2026-05-28
ThromboprophylaXIs with Factor XI/XIa inhibitors for venous thromboembolism
PorresAguilar et al. · Jornal vascular brasileiro
Added to ASH registry: 2026-05-28
Towards understanding the effect of fibrinogen interactions on fibrin gel structure.
Nelson et al. · Physical review. E
Added to ASH registry: 2026-05-28
Treatment of Factor-Xa Inhibitor-associated Bleeding with Andexanet Alfa or 4 Factor PCC: A Multicenter Feasibility Retrospective Study
Singer et al. · The western journal of emergency medicine
Added to ASH registry: 2026-05-28
Updated guidance for efficacy and safety outcomes for clinical trials in venous thromboembolism in children: communication from the ISTH SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis.
Whitworth H et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Venous and arterial thromboembolism after colorectal cancer in the Netherlands: Incidence, predictors, and prognosis.
Anijs et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Venous Thromboembolism Prophylaxis in Major Orthopedic Surgeries and Factor XIa Inhibitors
Jones et al. · Medical sciences (Basel, Switzerland)
Added to ASH registry: 2026-05-28
Venous thromboembolism: Exploring incidence and utility of screening in spinal cord injury.
Draganich et al. · The journal of spinal cord medicine
Added to ASH registry: 2026-05-28
Viscoelastic Testing Methods.
Carll · Advances in clinical chemistry
Added to ASH registry: 2026-05-28
Von Willebrand Disease, Hemophilia, and Other Inherited Bleeding Disorders in Pregnancy.
Pacheco LD et al. · Obstetrics and gynecology
Added to ASH registry: 2026-05-28
Warfarin vs doac: Comparative outcomes of mechanical thrombectomy for acute ischemic stroke in atrial fibrillation patients.
Ramazanoglu et al. · Clinical neurology and neurosurgery
Added to ASH registry: 2026-05-28
When and How to Use Reversal Agents for Direct Oral Anticoagulants?.
Gómez-Outes et al. · Current cardiology reports
Added to ASH registry: 2026-05-28
Alternative Non-Drug Treatment Options of the Most Neglected Parasitic Disease Cutaneous Leishmaniasis: A Narrative Review
Orabi MAA et al. · Tropical medicine and infectious disease
Added to ASH registry: 2026-05-27
Anticoagulation with Intravenous Direct Thrombin Inhibitors in Pediatric Extracorporeal Membrane Oxygenation: A Systematic Review of the Literature
Kiskaddon AL et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-27
Biomimetic platelet nanomotors for site-specific thrombolysis and ischemic injury alleviation
Chen YT et al. · ACS applied materials & interfaces
Added to ASH registry: 2026-05-27
Bivalirudin anticoagulation for cardiopulmonary bypass during cardiac surgery
Meshulami N et al. · Perfusion
Added to ASH registry: 2026-05-27
Bivalirudin for cardiopulmonary bypass in a patient with heparin allergy
Boysan E et al. · J Cardiothorac Surg
Added to ASH registry: 2026-05-27
Bivalirudin in acute coronary syndromes
Galli M et al. · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-27
Bivalirudin or heparin for systemic anticoagulation during pediatric extracorporeal membrane oxygenation: Multicenter retrospective study
Hamzah M et al. · Thrombosis research
Added to ASH registry: 2026-05-27
Bivalirudin versus heparin during PCI in NSTEMI: individual patient data meta-analysis of large randomized trials
Bikdeli B et al. · Circulation
Added to ASH registry: 2026-05-27
Bivalirudin versus heparin in contemporary percutaneous coronary interventions for patients with acute coronary syndrome: a systematic review and meta-analysis
Zhang J et al. · Cardiology journal
Added to ASH registry: 2026-05-27
Bivalirudin versus heparin in STEMI after BRIGHT-4 trial: an updated meta-analysis
Oli PR et al. · Coronary artery disease
Added to ASH registry: 2026-05-27
BRIGHT-4 trial: bivalirudin strikes back
Piriou PG et al. · Lancet
Added to ASH registry: 2026-05-27
BRIGHT-4 trial: bivalirudin strikes back - Authors' reply
Li Y et al. · Lancet
Added to ASH registry: 2026-05-27
Cloning, characterization, and heterologous expression of a candidate hirudin gene from the salivary gland transcriptome of Hirudo nipponia
Shi P et al. · Scientific reports
Added to ASH registry: 2026-05-27
Early and Empirical High-Dose Cryoprecipitate for Hemorrhage After Traumatic Injury: The CRYOSTAT-2 Randomized Clinical Trial
Davenport R et al. · JAMA
Added to ASH registry: 2026-05-27
Ecarin-based methods for measuring thrombin inhibitors
Gosselin RC · Methods in molecular biology
Added to ASH registry: 2026-05-27
Epidemiology of anticoagulation for children supported by extracorporeal membrane oxygenation in the United States: A Pediatric Hospital Information System database study
Nellis ME et al. · Perfusion
Added to ASH registry: 2026-05-27
Evaluation of Newly Integrated Bivalirudin Titration Protocol in Patients With Mechanical Circulatory Support
Mitchell M et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-27
Exploiting Chemical Protein Synthesis to Study the Role of Tyrosine Sulfation on Anticoagulants from Hematophagous Organisms
Maxwell JWC et al. · Accounts of chemical research
Added to ASH registry: 2026-05-27
First description study on molecular characterization of Hemiclepsis khankiana (Hirudinea: Glossiphoniidae) in China
He Y et al. · BMC Vet Res
Added to ASH registry: 2026-05-27
From haemadin to haemanorm: Synthesis and characterization of full-length haemadin from the leech Haemadipsa sylvestris and of a novel bivalent, highly potent thrombin inhibitor (haemanorm)
Acquasaliente L et al. · Protein science
Added to ASH registry: 2026-05-27
Functional expression of a thrombin exosite I inhibitor triabin in Escherichia coli
Mo Z et al. · Biochimie
Added to ASH registry: 2026-05-27
Heparin versus bivalirudin for anticoagulation in adult extracorporeal membrane oxygenation: a systematic review and meta-analysis
Wieruszewski PM et al. · ASAIO journal
Added to ASH registry: 2026-05-27
Heparin-based versus bivalirudin-based anticoagulation in pediatric extracorporeal membrane oxygenation: A systematic review
Valdes CA et al. · Frontiers in medicine
Added to ASH registry: 2026-05-27
Hirudin ameliorates myocardial ischemia-reperfusion injury in a rat model of hemorrhagic shock and resuscitation: roles of NLRP3-signaling pathway
Bai Y et al. · Molecular and cellular biochemistry
Added to ASH registry: 2026-05-27
Identification and Characterization of RK22, a Novel Antimicrobial Peptide from Hirudinaria manillensis against Methicillin Resistant Staphylococcus aureus
Lu X et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-27
Impact of coronary artery disease on clinical outcomes after TAVR: Insights from the BRAVO-3 randomized trial
Feldman D et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-27
Intraoperative Bivalirudin Use in Patient Undergoing Femoral Endarterectomy with Heparin-Induced Thrombocytopenia: Case Report and Review of the Literature
Haffler ZJ et al. · Vasc Endovascular Surg
Added to ASH registry: 2026-05-27
Intravenous Dabigatran Provides Adequate Anticoagulation for Cardiopulmonary Bypass Using a Rabbit Model
Nadtochiy SM et al. · Anesthesiology
Added to ASH registry: 2026-05-27
Isolation and characterization of poeciguamerin, a peptide with dual analgesic and antithrombotic activity from leech salivary glands
Wang et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-27
Lower Extremity Reconstruction with Anterolateral Thigh Free-Flap Anastomoses: A Computational Fluid Dynamic Analysis
Jinka SKA et al. · Journal of reconstructive microsurgery
Added to ASH registry: 2026-05-27
Marine vampires: Persistent, internal associations between bacteria and blood-feeding marine annelids and crustaceans
Goffredi SK et al. · Frontiers in microbiology
Added to ASH registry: 2026-05-27
Molecular cloning and functional analysis of HnSaratin from Hirudo nipponia
Cheng B et al. · Gene
Added to ASH registry: 2026-05-27
Near infrared spectroscopy in monitoring of head and neck microvascular free flaps
Czako L et al. · Bratislavske lekarske listy
Added to ASH registry: 2026-05-27
Novel fondaparinux protocol for anticoagulation therapy in adults with renal failure and suspected heparin-induced thrombocytopenia: a retrospective review of institutional protocol
Ghaziri D et al. · BMC pharmacology & toxicology
Added to ASH registry: 2026-05-27
Novel Knowledge about Molecular Mechanisms of Heparin-Induced Thrombocytopenia Type II and Treatment Targets
Mongirdiene A et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-27
Periprocedural antithrombotic strategies in acute coronary syndromes undergoing percutaneous coronary intervention: Have we discarded bivalirudin too soon?
Benenati S et al. · Cardiovasc Revasc Med
Added to ASH registry: 2026-05-27
Quantitative proteomics based bioactive proteins discovery and quality control of medicinal leeches
Li FG et al. · Journal of ethnopharmacology
Added to ASH registry: 2026-05-27
Recombinant Neorudin for the Prevention of Deep-Vein Thrombosis After Spinal-Cord Injury
Liu YB et al. · Drug Design Development and Therapy
Added to ASH registry: 2026-05-27
Sedation Research in Critically Ill Pediatric Patients: Proposals for Future Study Design From the Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research IV Workshop
Jackson SS et al. · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Added to ASH registry: 2026-05-27
Yeast surface display of leech hyaluronidase for the industrial production of hyaluronic acid oligosaccharides
Liao L et al. · Eng Microbiol
Added to ASH registry: 2026-05-27
The historical course of varicose vein surgery in the Persian medicine
Asadi MH et al. · Acta chirurgica Belgica
Added to ASH registry: 2026-05-26
Hirudin ameliorates diabetic nephropathy by inhibiting Gsdmd-mediated pyroptosis
Han J et al. · Cell biology and toxicology
Added to ASH registry: 2026-03-18
Hirudin versus citrate as an anticoagulant for ROTEM
Wickramasinghe W et al. · Platelets
Added to ASH registry: 2026-03-18
Intracerebral hirudin injection alleviates cognitive impairment and oxidative stress and promotes hippocampal neurogenesis in rats subjected to cerebral ischemia
Xia X et al. · Neuropathology : official journal of the Japanese Society of Neuropathology
Added to ASH registry: 2026-03-18
Keratitis following leech therapy for periocular eczematous dermatitis: a case report
Özkaya D · BMC complementary medicine and therapies
Added to ASH registry: 2026-03-18
Revisiting the Asian Buffalo Leech (
Liu Z et al. · Genes
Added to ASH registry: 2026-03-18
Structural insights into thrombolytic activity of destabilase from medicinal leech
Marin E et al. · Scientific reports
Added to ASH registry: 2026-03-18
2022
157 articlesBivalirudin exerts antiviral activity against respiratory syncytial virus-induced lung infections in neonatal mice
Zhuang et al. · Acta pharmaceutica (Zagreb, Croatia)
Added to ASH registry: 2026-05-29
Bivalirudin in patients with ST-segment elevation myocardial infarction
Coughlan et al. · Lancet (London, England)
Added to ASH registry: 2026-05-29
Bivalirudin Presents a Favorable Safety Profile Regarding Adverse Drug Reactions, Thrombocytopenia, and Bleeding in Chinese Patients With High Bleeding Risk Undergoing Percutaneous Coronary Intervention: A Prospective, Multi-Center, Intensive Monitoring Study
Peng et al. · Frontiers in cardiovascular medicine
Added to ASH registry: 2026-05-29
Bivalirudin vs. heparin on a background of ticagrelor and aspirin in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: A multicenter prospective cohort study
Yu et al. · Frontiers in cardiovascular medicine
Added to ASH registry: 2026-05-29
Comprehensive safety profile evaluation of bivalirudin in Chinese ST-segment elevation myocardial infarction patients receiving percutaneous coronary intervention: a prospective, multicenter, intensive monitoring study
Zheng et al. · BMC cardiovascular disorders
Added to ASH registry: 2026-05-29
Effectiveness and safety of bivalirudin in elderly patients with coronary artery disease undergoing percutaneous coronary intervention: A real-world study
Li et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-29
Efficacy and safety of bivalirudin without post-procedure infusion in patients with coronary heart disease during elective percutaneous coronary intervention: a real-world study
Wang et al. · Chinese medical journal
Added to ASH registry: 2026-05-29
Efficacy and Safety of the Reduced Bivalirudin in Patients Undergoing Coronary Angiography or Percutaneous Coronary Intervention Stratified by Renal Function (REDUCE BOLUS): A Single-Blind, Stratified Randomized, Non-inferiority Trial
Hu et al. · Frontiers in cardiovascular medicine
Added to ASH registry: 2026-05-29
Impact of Diabetes Mellitus on One-Year Clinical Outcomes in Patients Anticoagulated with Bivalirudin Undergoing Elective Percutaneous Coronary Intervention
Li et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-29
Low-dose apixaban in extended treatment of cancer-associated thrombosis: Less is more?
Barca-Hernando et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-29
Safety and Efficacy of Bivalirudin versus Unfractionated Heparin Monotherapy in Patients with CAD and DM Undergoing PCI: A Retrospective Observational Study
Li et al. · Cardiovascular therapeutics
Added to ASH registry: 2026-05-29
[Treatment of cancer associated thrombosis].
Sanchez O · La Revue du praticien
Added to ASH registry: 2026-05-28
A Factor XIa Inhibitor Engineered from Banded Krait Venom Toxin: Efficacy and Safety in Rodent Models of Arterial and Venous Thrombosis
Chng et al. · Biomedicines
Added to ASH registry: 2026-05-28
A novel inhibitor of Factor XIa as potential haemostasis-sparing anticoagulant for patients with atrial fibrillation
Liuzzo et al. · European heart journal
Added to ASH registry: 2026-05-28
A proposal for managing bleeding in patients on therapeutic factor XI(a) inhibitors
Salomon et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
A short review of ciraparantag in perspective of the currently available anticoagulant reversal agents.
Leentjens et al. · Drug discovery today
Added to ASH registry: 2026-05-28
A systematic review and meta-analysis of dabigatran peak and trough concentration in adults
Ng et al. · British journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Advances in Acute Ischemic Stroke Therapy.
Xiong Y et al. · Circulation research
Added to ASH registry: 2026-05-28
Alteplase or tenecteplase for thrombolysis in ischemic stroke: An illustrated review.
Zhu A et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
An Analysis of the Sensitivity of the Activated Partial Thromboplastin Time (APTT) Assay, as Used in a Large Laboratory Network, to Coagulation Factor Deficiencies.
Do et al. · American journal of clinical pathology
Added to ASH registry: 2026-05-28
Analysis of the Preventive Action of Rivaroxaban against Lower Extremity Deep Venous Thrombosis in Patients after Laparoscopic Radical Gastrectomy
Dong et al. · Computational and mathematical methods in medicine
Added to ASH registry: 2026-05-28
Andexanet alfa and four-factor prothrombin complex concentrate for reversal of apixaban and rivaroxaban in patients diagnosed with intracranial hemorrhage
Vestal et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Andexanet Alfa for Reversal of Factor Xa Inhibitors in Intracranial Hemorrhage: Observational Cohort Study.
Rauch et al. · Journal of clinical medicine
Added to ASH registry: 2026-05-28
Andexanet alfa versus four-factor prothrombin complex concentrate for the reversal of apixaban- or rivaroxaban-associated intracranial hemorrhage: a propensity score-overlap weighted analysis
Costa et al. · Critical care (London, England)
Added to ASH registry: 2026-05-28
Anti-Xa Levels in Morbidly Obese Patients Using Apixaban or Rivaroxaban, Before and After Bariatric Surgery
Kok et al. · Obesity surgery
Added to ASH registry: 2026-05-28
Apixaban and Rivaroxaban Anti-Xa Level Monitoring Versus Standard Monitoring in Hospitalized Patients With Acute Kidney Injury
Towers et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Apixaban and rivaroxaban anti-Xa level utilization for guidance of administration of andexanet alfa: a case series
Morton et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Apixaban in Japanese patients with cancer-associated venous thromboembolism: a multi-center phase II trial
Imamura et al. · International journal of hematology
Added to ASH registry: 2026-05-28
Apixaban versus Warfarin for Treatment of Venous Thromboembolism in Patients Receiving Long-Term Dialysis
Wetmore et al. · Clinical journal of the American Society of Nephrology : CJASN
Added to ASH registry: 2026-05-28
Atraumatic splenic rupture in a patient treated with rivaroxaban: A case report and a narrative review
Labaki et al. · Clinical case reports
Added to ASH registry: 2026-05-28
Atrial Fibrillation in a Patient with Heparin-induced Thrombocytopenia Successfully Treated by Radiofrequency Catheter Ablation Using a Direct Thrombin Inhibitor
Sakai T et al. · Internal medicine (Tokyo, Japan)
Added to ASH registry: 2026-05-28
Balloon pulmonary angioplasty versus riociguat in inoperable chronic thromboembolic pulmonary hypertension (MR BPA): an open-label, randomised controlled trial.
Kawakami T et al. · The Lancet. Respiratory medicine
Added to ASH registry: 2026-05-28
Bivalirudin versus heparin in adult and pediatric patients with extracorporeal membrane oxygenation therapy: A systematic review and meta-analysis
Liu et al. · Pharmacological research
Added to ASH registry: 2026-05-28
Bivalirudin vs. heparin in paediatric and adult patients on extracorporeal membrane oxygenation: A meta-analysis
Li et al. · British journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Catheter directed thrombolysis for deep vein thrombosis in 2022: Rationale, evidence base and future directions.
Khalid MU et al. · International journal of cardiology
Added to ASH registry: 2026-05-28
Catheter-directed therapies for the treatment of high risk (massive) and intermediate risk (submassive) acute pulmonary embolism.
Harvey JJ et al. · The Cochrane database of systematic reviews
Added to ASH registry: 2026-05-28
Catheter-Directed Thrombolysis vs Anticoagulation in Patients With Acute Intermediate-High-risk Pulmonary Embolism: The CANARY Randomized Clinical Trial.
Sadeghipour P et al. · JAMA cardiology
Added to ASH registry: 2026-05-28
Ciraparantag as a potential universal anticoagulant reversal agent.
Chan et al. · European heart journal
Added to ASH registry: 2026-05-28
Ciraparantag reverses the anticoagulant activity of apixaban and rivaroxaban in healthy elderly subjects.
Ansell et al. · European heart journal
Added to ASH registry: 2026-05-28
Clonal Dissemination ofWith Binary Carriage of-Bearing Plasmids in a Chinese Hospital.
Xu Z et al. · Frontiers in microbiology
Added to ASH registry: 2026-05-28
Comparison of Interrupted and Uninterrupted Anticoagulation Therapy for Patients With Atrial Fibrillation Undergoing Catheter Ablation: A Meta-Analysis.
Jamil S et al. · Cureus
Added to ASH registry: 2026-05-28
Comparison of Managing Factor Xa Inhibitor to Unfractionated Heparin Transitions by aPTT Versus a Treatment Guideline Utilizing Heparin Anti-Xa Levels
Dingus et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Cost-Utility Analysis Comparing Direct Oral Anticoagulant and Low Molecular Weight Heparin Therapies for Secondary Prevention of Cancer-Associated Thrombosis.
Shin YE et al. · Clinical drug investigation
Added to ASH registry: 2026-05-28
Cystine Knot Peptides with Tuneable Activity and Mechanism
Li et al. · Angewandte Chemie (International ed. in English)
Added to ASH registry: 2026-05-28
Dabigatran Etexilate: A Review in Pediatric Venous Thromboembolism
Paik · Paediatric drugs
Added to ASH registry: 2026-05-28
Development of three ecological spectroscopic methods for analysis of betrixaban either alone or in mixture with lercanidipine: greenness assessment
El-Masry et al. · Royal Society open science
Added to ASH registry: 2026-05-28
Differential Neutralization of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban by Andexanet Alfa as Measured by Whole Blood Thromboelastographic Analysis
Mehrotra et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Direct oral anticoagulants for use in paediatrics
Jaffray et al. · The Lancet. Child & adolescent health
Added to ASH registry: 2026-05-28
Direct oral to parenteral anticoagulant transitions: Role of factor Xa inhibitor-specific anti-Xa concentrations
Dinunno et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Discovery of Potent and Orally Bioavailable Pyridine N-Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions
Xu et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Disseminated Intravascular Coagulation: The Past, Present, and Future Considerations.
Iba et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Downregulation of thrombomodulin-thrombin-activated protein C pathway as a mechanism for SARS-CoV-2 induced endotheliopathy and microvascular thrombosis.
Agarwal et al. · Thrombosis update
Added to ASH registry: 2026-05-28
Drug-Drug Interactions of Direct Oral Anticoagulants (DOACs): From Pharmacological to Clinical Practice.
Ferri N et al. · Pharmaceutics
Added to ASH registry: 2026-05-28
Edoxaban in cardiovascular disease management: Review
Srinivasan et al. · British journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Effect of Anticoagulant Therapy for 6 Weeks vs 3 Months on Recurrence and Bleeding Events in Patients Younger Than 21 Years of Age With Provoked Venous Thromboembolism: The Kids-DOTT Randomized Clinical Trial.
Goldenberg NA et al. · JAMA
Added to ASH registry: 2026-05-28
Effectiveness and Safety of Nonvitamin K Oral Anticoagulants Rivaroxaban and Apixaban in Patients with Venous Thromboembolism: A Meta-Analysis of Real-World Studies
Wu et al. · Cardiovascular therapeutics
Added to ASH registry: 2026-05-28
Efficacy and safety of rivaroxaban in cerebral venous thrombosis: insights from a prospective cohort study
Pan et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Epidemiology and prevention of venous thromboembolism.
Lutsey et al. · Nature reviews. Cardiology
Added to ASH registry: 2026-05-28
Evaluation of Anti-Xa Apixaban and Rivaroxaban Levels With Respect to Known Doses in Relation to Major Bleeding Events
Nguyen et al. · Journal of pharmacy practice
Added to ASH registry: 2026-05-28
Evaluation of bleeding and anticoagulation markers by edoxaban and low-dose cyclosporine: A case series study
Hirai et al. · Biopharmaceutics & drug disposition
Added to ASH registry: 2026-05-28
Factor XI Activation Inhibitors for Treating Thromboses, Embolism, Hypercoagulability, or Fibrotic Changes
Sabnis et al. · ACS medicinal chemistry letters
Added to ASH registry: 2026-05-28
Factor XIa Inhibition: Is It a Novel Alternative Antithrombotic Strategy for High-Risk ACS Patients?
Gue et al. · Circulation
Added to ASH registry: 2026-05-28
First-In-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of SHR2285, a Small-Molecule Factor XIa Inhibitor in Healthy Subjects
Chen et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-28
Four-factor prothrombin complex concentrate plus andexanet alfa for reversal of factor Xa inhibitor-associated bleeding: Case series
Liu et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Harmonizing factor assay-related testing performed in a large laboratory network.
Favaloro et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Heparin-Induced Thrombocytopenia in COVID-19: A Systematic Review.
Sulakshana S et al. · Anesthesia, essays and researches
Added to ASH registry: 2026-05-28
Heparin-induced Thrombocytopenia: Perioperative Diagnosis and Management
Koster et al. · Anesthesiology
Added to ASH registry: 2026-05-28
How does the use of antiplatelet and anticoagulants affect the success of mechanical thrombectomy in acute ischemic stroke cases?
Çabalar et al. · Ideggyogyaszati szemle
Added to ASH registry: 2026-05-28
How to dose and monitor argatroban for treatment of HIT
Warkentin TE · British journal of haematology
Added to ASH registry: 2026-05-28
Impact of Factor Xa Inhibitor Reversal with Prothrombin Complex Concentrate in Patients with Traumatic Brain Injuries
Cooksey et al. · Neurocritical care
Added to ASH registry: 2026-05-28
Impact of Fibrinogen Infusion on Thrombin Generation and Fibrin Clot Structure in Patients with Inherited Afibrinogenemia.
Khayat et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Impact of intracoronary reteplase during primary percutaneous coronary intervention on infarct size in large anterior myocardial infarction: rationale and design of the RECOVER II trial.
Huang D et al. · Cardiovascular diagnosis and therapy
Added to ASH registry: 2026-05-28
Incidence and risk factors for venous thromboembolism, bleeding, and death in colorectal cancer (Cancer-VTE Registry).
Ikeda et al. · Cancer science
Added to ASH registry: 2026-05-28
Incidence, characteristics, and risk factors of venous thromboembolism in shoulder arthroplasty-a systematic review.
Na et al. · International orthopaedics
Added to ASH registry: 2026-05-28
Initial Experience with Apixaban for Extended Venous Thromboembolism Prophylaxis After Radical Cystectomy
Rosen et al. · European urology focus
Added to ASH registry: 2026-05-28
Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial.
Menon BK et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
Is bivalirudin an alternative anticoagulant for extracorporeal membrane oxygenation (ECMO) patients? A systematic review and meta-analysis
Li et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Left Atrial Appendage Occlusion: Practice Makes Perfect?
Tang SA et al. · JACC. Cardiovascular interventions
Added to ASH registry: 2026-05-28
Mechanical Thrombectomy in Patients with Acute Ischemic Stroke and Concomitant Intracranial Hemorrhage.
Weller et al. · Clinical neuroradiology
Added to ASH registry: 2026-05-28
NEOnatal Central-venous Line Observational study on Thrombosis (NEOCLOT): evaluation of a national guideline on management of neonatal catheter-related venous thrombosis.
van Ommen et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
New Blood Coagulation Factor XIIa Inhibitors: Molecular Modeling, Synthesis, and Experimental Confirmation
Tashchilova et al. · Molecules (Basel, Switzerland)
Added to ASH registry: 2026-05-28
New Insights on Uninterrupted Anticoagulation in Left Atrial Catheter Ablation Procedures.
Kondo Y et al. · Circulation journal : official journal of the Japanese Circulation Society
Added to ASH registry: 2026-05-28
Novel factor XIa inhibitor reduces bleeding compared with apixaban in atrial fibrillation
Lim et al. · Nature reviews. Cardiology
Added to ASH registry: 2026-05-28
Optimal timing of anticoagulation after acute ischemic stroke with atrial fibrillation (OPTIMAS): Protocol for a randomized controlled trial.
Best et al. · International journal of stroke : official journal of the International Stroke Society
Added to ASH registry: 2026-05-28
Outcomes after Rivaroxaban Treatment of Extensive Deep Vein Thrombosis
Fujioka et al. · Annals of vascular surgery
Added to ASH registry: 2026-05-28
Outcomes of single digit replantation for amputation proximal to the flexor digitorum superficialis insertion: A systematic review with meta-analysis
Wong S et al. · Microsurgery
Added to ASH registry: 2026-05-28
Personalizing Direct Oral Anticoagulant Therapy for a Diverse Population: Role of Race, Kidney Function, Drug Interactions, and Pharmacogenetics.
Thompson LE et al. · Clinical pharmacology and therapeutics
Added to ASH registry: 2026-05-28
Pharmacokinetics and pharmacodynamics of Abelacimab (MAA868), a novel dual inhibitor of Factor XI and Factor XIa
Yi et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Pipiserpin, a Culex factor Xa inhibitor, affects female reproductive capacity and serves as a potential target for mosquito control
Zhang et al. · Pest management science
Added to ASH registry: 2026-05-28
Platelet function testing: Current practice among clinical centres in Northern Europe.
Szanto et al. · Haemophilia : the official journal of the World Federation of Hemophilia
Added to ASH registry: 2026-05-28
Platelet Function Testing: Update and Future Directions.
Larsen et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Platelet tissue factor pathway inhibitor-α dampens cardiac thrombosis and associated fibrosis in mice.
Maroney et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Platelet-Covered Nanocarriers for Targeted Delivery of Hirudin to Eliminate Thrombotic Complication in Tumor Therapy
Zhang et al. · ACS nano
Added to ASH registry: 2026-05-28
Pregnancy After Cardiac Surgery.
Makhija et al. · Cureus
Added to ASH registry: 2026-05-28
Prevalence and outcomes of patients developing heparin-induced thrombocytopenia during extracorporeal membrane oxygenation
Lubnow et al. · PloS one
Added to ASH registry: 2026-05-28
Proline-Rich Region II (PRR2) Plays an Important Role in Tau-Glycan Interaction: An NMR Study.
Murray A et al. · Biomolecules
Added to ASH registry: 2026-05-28
Pulmonary embolism management in the emergency department: part 2.
Serebriakoff et al. · Emergency medicine journal : EMJ
Added to ASH registry: 2026-05-28
Recommendations for standardized definitions, clinical assessment, and future research in pediatric clinically unsuspected venous thromboembolism: Communication from the ISTH SSC subcommittee on pediatric and neonatal thrombosis and hemostasis.
Betensky M et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Renal function and clinical outcome of patients with cancer-associated venous thromboembolism randomized to receive apixaban or dalteparin. Results from the Caravaggio trial.
Becattini C et al. · Haematologica
Added to ASH registry: 2026-05-28
Riociguat and the right ventricle in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
Benza RL et al. · European respiratory review : an official journal of the European Respiratory Society
Added to ASH registry: 2026-05-28
Risk for Recurrent Venous Thromboembolism and Bleeding With Apixaban Compared With Rivaroxaban: An Analysis of Real-World Data
Dawwas et al. · Annals of internal medicine
Added to ASH registry: 2026-05-28
Rivaroxaban for the treatment of cerebral venous thrombosis: a single-center experience
Bajko et al. · Acta neurologica Belgica
Added to ASH registry: 2026-05-28
Rivaroxaban Prophylaxis in Noncirrhotic Portal Vein Thrombosis
Plessier et al. · NEJM evidence
Added to ASH registry: 2026-05-28
Rivaroxaban treatment for six weeks versus three months in patients with symptomatic isolated distal deep vein thrombosis: randomised controlled trial
Ageno et al. · BMJ (Clinical research ed.)
Added to ASH registry: 2026-05-28
Role of anticoagulants in therapy and prevention of recurrent venous thromboembolism in patients with cancer: a meta-analysis of randomized trials with apixaban
Mareev et al. · Kardiologiia
Added to ASH registry: 2026-05-28
Safety and efficacy of apixaban and rivaroxaban in obese patients with acute venous thrombosis/embolism
Anusim et al. · European journal of haematology
Added to ASH registry: 2026-05-28
Safety and Efficacy of Rivaroxaban for Inferior Vena Cava Thrombosis after Successful Catheter-Directed Thrombolysis
Du et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Safety profile of bivalirudin in Chinese female patients undergoing percutaneous coronary intervention: a multi-center study.
Wu F et al. · BMC cardiovascular disorders
Added to ASH registry: 2026-05-28
Safety, pharmacokinetics, and pharmacodynamics of milvexian in healthy Japanese participants
Perera et al. · Scientific reports
Added to ASH registry: 2026-05-28
Single-Dose Pharmacokinetics of Milvexian in Participants with Mild or Moderate Hepatic Impairment Compared with Healthy Participants
Perera et al. · Clinical pharmacokinetics
Added to ASH registry: 2026-05-28
Single-Dose Pharmacokinetics of Milvexian in Participants with Normal Renal Function and Participants with Moderate or Severe Renal Impairment
Perera et al. · Clinical pharmacokinetics
Added to ASH registry: 2026-05-28
Structure-Based Design of High-Affinity and Selective Peptidomimetic Hepsin Inhibitors
Knaff et al. · Biomacromolecules
Added to ASH registry: 2026-05-28
Sulfonated non-saccharide molecules and human factor XIa: Enzyme inhibition and computational studies
Al-Horani et al. · Chemical biology & drug design
Added to ASH registry: 2026-05-28
Surface functionalization of anticoagulation and anti-nonspecific adsorption with recombinant hirudin modification
Zheng et al. · Biomaterials advances
Added to ASH registry: 2026-05-28
Systematic review of drug-drug interactions between rifamycins and anticoagulant and antiplatelet agents and considerations for management.
MacDougall C et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Targeting the S2 Subsite Enables the Structure-Based Discovery of Novel Highly Selective Factor XIa Inhibitors
Yao et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
The More Recent History of Hemophilia Treatment.
Franchini M et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Treatment Options for Venous Thromboembolism in Patients Receiving Dialysis
Mavrakanas · Clinical journal of the American Society of Nephrology : CJASN
Added to ASH registry: 2026-05-28
Uninterrupted DOACs Approach for Catheter Ablation of Atrial Fibrillation: Do DOACs Levels Matter?
Hardy M et al. · Frontiers in cardiovascular medicine
Added to ASH registry: 2026-05-28
Using a low-molecular weight heparin-calibrated anti-factor Xa assay to assess the concentration of apixaban and rivaroxaban
von Horn et al. · International journal of laboratory hematology
Added to ASH registry: 2026-05-28
Utilization of apixaban anti-Xa levels in transition from apixaban to warfarin in a patient with chronic renal dysfunction
Elgersma et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
A journey through anticoagulant therapies in the treatment of left ventricular thrombus in post-COVID-19 heparin-induced thrombocytopenia: a case report
Lazaro-Garcia A et al. · Hematology
Added to ASH registry: 2026-05-27
Application of the C3 inhibitor compstatin in a human whole blood model designed for complement research - 20 years of experience and future perspectives
Mollnes TE et al. · Seminars in immunology
Added to ASH registry: 2026-05-27
Bivalirudin and Venoarterial Extracorporeal Membrane Oxygenation for Treatment of Massive Pulmonary Embolism From Heparin-Induced Thrombocytopenia With Thrombosis
Kawaji Q et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
Bivalirudin anticoagulation in neonates and infants undergoing cardiac surgery
Hasija S et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
Bivalirudin in pediatric extracorporeal membrane oxygenation
Ryerson LM et al. · Current opinion in pediatrics
Added to ASH registry: 2026-05-27
Bivalirudin or Unfractionated Heparin for Anticoagulation in Pediatric Patients on Continuous Flow Ventricular Assist Device Support: Single-Center Retrospective Cohort Study
Puri K et al. · Pediatric critical care medicine
Added to ASH registry: 2026-05-27
Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomised trial
Li Y et al. · Lancet
Added to ASH registry: 2026-05-27
Bivalirudin versus heparin anticoagulation in patients receiving extracorporeal membrane oxygenation
Huang D et al. · Perfusion
Added to ASH registry: 2026-05-27
Comparison of bivalirudin versus unfractionated heparin for anticoagulation in adult patients on extracorporeal membrane oxygenation
Sheridan EA et al. · ASAIO journal
Added to ASH registry: 2026-05-27
Evaluation of anticoagulation with bivalirudin for heparin-induced thrombocytopenia during extracorporeal membrane oxygenation
Hanna DJ et al. · International journal of artificial organs
Added to ASH registry: 2026-05-27
First data on the Hirudinea fauna of lotic ecosystems of the Khanty-Mansi Autonomous Area (Russia)
Fedorova LI et al. · ZooKeys
Added to ASH registry: 2026-05-27
Hirudin alleviates acute ischemic stroke by inhibiting NLRP3 inflammasome-mediated neuroinflammation
Li WQ et al. · International immunopharmacology
Added to ASH registry: 2026-05-27
Hirudin alleviates acute ischemic stroke by inhibiting NLRP3 inflammasome-mediated neuroinflammation: In vivo and in vitro approaches
Li WQ et al. · International Immunopharmacology
Added to ASH registry: 2026-05-27
Hirudin promotes proliferation and osteogenic differentiation of HBMSCs via activation of cGMP/PKG signaling pathway
Cao S et al. · Bioengineered
Added to ASH registry: 2026-05-27
LC-MS/MS method for determination of r-RGD-hirudin in human plasma and its application in pharmacokinetic study
Peng A et al. · Analytical biochemistry
Added to ASH registry: 2026-05-27
Lessons Learned from Managing Antithrombotic Therapy in Children Supported with Pediatric Ventricular Assist Devices
Murray JM et al. · ASAIO journal
Added to ASH registry: 2026-05-27
Negative Pressure Wound Therapy as an Artificial Leech to Save a Congestive Flap: Case Report
Ardila MP et al. · Plastic and reconstructive surgery. Global open
Added to ASH registry: 2026-05-27
Network pharmacology and experimental verification reveal the mechanism of hirudin in suppressing myocardial hypertrophy
Liu M et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-27
Neurocoagulation from a Mechanistic Point of View in the Central Nervous System
Shavit-Stein E et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-27
Novel contact-kinin inhibitor sylvestin targets thromboinflammation and ameliorates ischemic stroke
Zhang Z et al. · Cellular and molecular life sciences
Added to ASH registry: 2026-05-27
Outcomes of systemic bivalirudin and sodium bicarbonate purge solution for Impella 5.5
Bashline M et al. · Artificial organs
Added to ASH registry: 2026-05-27
Production of a murine mAb against Bothrops alternatus and B. neuwiedi snake venoms and its use to isolate a thrombin-like serine protease fraction
Belo AA et al. · International journal of biological macromolecules
Added to ASH registry: 2026-05-27
Purification and characterization of a novel thermostable anticoagulant protein from medicinal leech Whitmania pigra Whitman
Zhang Y et al. · Journal of Ethnopharmacology
Added to ASH registry: 2026-05-27
Research progress on processing history evolution, chemical constituents, and pharmacological effects of Hirudo
Jiang Q et al. · Zhongguo Zhong yao za zhi
Added to ASH registry: 2026-05-27
SARS-CoV-2 triggers complement activation through interactions with heparan sulfate
Lo MW et al. · Clinical & translational immunology
Added to ASH registry: 2026-05-27
Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release
de Boer E et al. · Journal of immunology (Baltimore, Md. : 1950)
Added to ASH registry: 2026-05-27
The Antithrombotic Effect of Recombinant Neorudin on Thrombi
Liu YB et al. · Drug Design Development and Therapy
Added to ASH registry: 2026-05-27
The Changing Landscape of Anticoagulation in Pediatric Extracorporeal Membrane Oxygenation: Use of the Direct Thrombin Inhibitors
Neunert C et al. · Frontiers in medicine
Added to ASH registry: 2026-05-27
Thrombin Differentially Modulates the Acute Inflammatory Response to E. coli and S. aureus in Human Whole Blood
Johnson C et al. · Journal of immunology
Added to ASH registry: 2026-05-27
Tyrosine-O-sulfation is a widespread affinity enhancer among thrombin interactors
Ripoll-Rozada J et al. · Biochemical Society transactions
Added to ASH registry: 2026-05-27
Management of Artery-Only Digit Replantation: A Systematic Review of the Literature
Crowe CS et al. · Plastic and reconstructive surgery
Added to ASH registry: 2026-05-26
Purification and characterization of a novel thermostable anticoagulant protein from medicinal leech Whitmania pigra
Zhang Y et al. · Journal of ethnopharmacology
Added to ASH registry: 2026-05-26
Shuxuetong injection and its peptides enhance angiogenesis after hindlimb ischemia by activating the MYPT1/LIMK1/Cofilin pathway
Sun W et al. · Journal of ethnopharmacology
Added to ASH registry: 2026-05-26
From ancient leech to direct thrombin inhibitors and beyond: New from old
Montinari M, Minelli S · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Added to ASH registry: 2026-03-18
Make it double: identification and characterization of a Tandem-Hirudin from the Asian medicinal leech Hirudinaria manillensis
Lukas P et al. · Parasitology research
Added to ASH registry: 2026-03-18
Molecular dynamic and pharmacological studies on protein-engineered hirudin variants of Hirudinaria manillensis and Hirudo medicinalis
Sun Y et al. · British journal of pharmacology
Added to ASH registry: 2026-03-18
Earlier
2179 articles (pre-2022)Bleeding in Patients With Gastrointestinal Cancer Compared With Nongastrointestinal Cancer Treated With Apixaban, Rivaroxaban, or Enoxaparin for Acute Venous Thromboembolism
Houghton et al. · Mayo Clinic proceedings
Added to ASH registry: 2026-05-29
Effects of Bivalirudin and Unfractionated Heparin on Liver and Renal Function in Chinese Patients with Coronary Artery Disease Undergoing Coronary Angiography with/without Percutaneous Coronary Intervention
Jia et al. · Journal of clinical and translational hepatology
Added to ASH registry: 2026-05-29
Evaluation of Bivalirudin-Associated Major Adverse Cardiac and Hemorrhagic Events in Acute Coronary Syndrome Patients on Chronic Dialysis Following Percutaneous Coronary Intervention
Fu et al. · The Journal of invasive cardiology
Added to ASH registry: 2026-05-29
Occurrence and Risk Factors of Adverse Drug Reactions in Patients Receiving Bivalirudin as Anticoagulant During Percutaneous Coronary Intervention: A Prospective, Multi-Center, Intensive Monitoring Study
Li et al. · Frontiers in cardiovascular medicine
Added to ASH registry: 2026-05-29
Safety and Effectiveness of Bivalirudin for Perioperative Anticoagulation in a Patient With Hemophilia A Undergoing Percutaneous Coronary Intervention
Luo et al. · The American journal of the medical sciences
Added to ASH registry: 2026-05-29
Safety of Apixaban for Cancer-Associated Thrombosis
Bikdeli et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-29
2021 Update of the International Council for Standardization in Haematology Recommendations for Laboratory Measurement of Direct Oral Anticoagulants
Douxfils et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
A comprehensive appraisal of dabigatran etexilate clinical evidence and applications: a 10-year-long story
Romiti et al. · Future cardiology
Added to ASH registry: 2026-05-28
A direct thrombin inhibitor, dabigatran etexilate protects from renal fibrosis by inhibiting protease activated receptor-1
Saifi et al. · European journal of pharmacology
Added to ASH registry: 2026-05-28
A meta-analysis and cost-minimization analysis of bivalirudin versus heparin in high-risk patients for percutaneous coronary intervention
Sun et al. · Pharmacology research & perspectives
Added to ASH registry: 2026-05-28
A Meta-analysis of Clinical Trials Evaluating the Impact of Bivalirudin-based Anticoagulation for Primary Percutaneous Coronary on Long-Term Mortality
Jagadish et al. · Journal of cardiovascular pharmacology
Added to ASH registry: 2026-05-28
A rechargeable anti-thrombotic coating for blood-contacting devices.
Ham et al. · Biomaterials
Added to ASH registry: 2026-05-28
A synergy of liquid chromatography with high-resolution mass spectrometry and coagulation test for determination of direct oral anticoagulants for clinical and toxicological purposes
Maier et al. · Biomedical chromatography : BMC
Added to ASH registry: 2026-05-28
A systematic review of apixaban in prevention and treatment of cancer-associated venous thromboembolism
Caputo et al. · Journal of the American Pharmacists Association : JAPhA
Added to ASH registry: 2026-05-28
Abelacimab and factor XI inhibition: a novel mechanism for the prevention of venous thromboembolism
Narducci et al. · European heart journal
Added to ASH registry: 2026-05-28
Abelacimab for Prevention of Venous Thromboembolism
Verhamme et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Abelacimab for Prevention of Venous Thromboembolism
Wang. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Abelacimab for Prevention of Venous Thromboembolism
Toom et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Abelacimab for Prevention of Venous Thromboembolism
Gallagher. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Abelacimab for Prevention of Venous Thromboembolism. Reply
Weitz et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Acute Management of High-Risk and Intermediate-Risk Pulmonary Embolism in Children: A Review.
Ross et al. · Chest
Added to ASH registry: 2026-05-28
Alzheimer's Disease-Rationales for Potential Treatment with the Thrombin Inhibitor Dabigatran
Grossmann · International journal of molecular sciences
Added to ASH registry: 2026-05-28
Amplatzer Amulet Left Atrial Appendage Occluder Versus Watchman Device for Stroke Prophylaxis (Amulet IDE): A Randomized, Controlled Trial.
Lakkireddy D et al. · Circulation
Added to ASH registry: 2026-05-28
Andexanet Alfa for Factor Xa Inhibitor-Associated Intracerebral Hemorrhage: Does a Specific Reversal Agent Justify Its Cost?.
Patel et al. · Neurology
Added to ASH registry: 2026-05-28
Andexanet Alfa or Prothrombin Complex Concentrate for Factor Xa Inhibitor Reversal in Acute Major Bleeding: A Systematic Review and Meta-Analysis.
Nederpelt et al. · Critical care medicine
Added to ASH registry: 2026-05-28
Andexanet Alfa Use in Cardiac Surgical Patients: A Xa Inhibitor and Heparin Reversal Agent.
Levy et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-28
AngioJet Thrombectomy Versus Catheter-Directed Thrombolysis for Lower Extremity Deep Vein Thrombosis: A Meta-Analysis of Clinical Trials.
Li GQ et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Anticoagulation for COVID-19 Patients: A Bird's-Eye View
Kreidieh et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Anticoagulation in patients with acute kidney injury undergoing kidney replacement therapy.
Raina et al. · Pediatric nephrology (Berlin, Germany)
Added to ASH registry: 2026-05-28
Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel Report.
Stevens et al. · Chest
Added to ASH registry: 2026-05-28
Antithrombotic therapy in patients with atrial fibrillation and acute coronary syndrome undergoing percutaneous coronary intervention; insights from a meta-analysis.
Kuno et al. · Coronary artery disease
Added to ASH registry: 2026-05-28
Apixaban and Dalteparin for the Treatment of Venous Thromboembolism in Patients with Different Sites of Cancer.
Agnelli G et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Apixaban in low-weight patients with cancer-associated thrombosis: A cross sectional study of drug levels.
Bravo Villa V et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Argatroban Anticoagulation for Adult Extracorporeal Membrane Oxygenation: A Systematic Review
Geli J et al. · Journal of intensive care medicine
Added to ASH registry: 2026-05-28
Argatroban Versus Bivalirudin in the Treatment of Suspected or Confirmed Heparin-Induced Thrombocytopenia
Duewell et al. · Journal of pharmacy practice
Added to ASH registry: 2026-05-28
ASH ISTH NHF WFH 2021 guidelines on the management of von Willebrand disease.
Connell et al. · Blood advances
Added to ASH registry: 2026-05-28
Baveno VII - Renewing consensus in portal hypertension.
de Franchis et al. · Journal of hepatology
Added to ASH registry: 2026-05-28
Binding of direct oral anticoagulants to the FA1 site of human serum albumin
De et al. · Journal of molecular recognition : JMR
Added to ASH registry: 2026-05-28
Bivalirudin for the prevention of hepatic artery thrombosis in pediatric liver transplantation
Craig-Schapiro et al. · Pediatric transplantation
Added to ASH registry: 2026-05-28
Bivalirudin in patients undergoing percutaneous coronary intervention and independent predictors of postoperative adverse events in these patients: A real world retrospective study.
Hu Y et al. · Medicine
Added to ASH registry: 2026-05-28
Bivalirudin Use for Primary Percutaneous Coronary Intervention on Long-Term Mortality
Caturano · Journal of cardiovascular pharmacology
Added to ASH registry: 2026-05-28
Cancer-Associated Splanchnic Vein Thrombosis.
Cohen et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Catheter-directed thrombolysis for deep vein thrombosis: 2021 update.
Goldhaber SZ et al. · Vascular medicine (London, England)
Added to ASH registry: 2026-05-28
Cerebral Venous Thrombosis.
Ropper et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Characterization of a novel toll-like receptor and activation NF-κB signal pathway in triangle sail mussel Hyriopsis cumingii.
Yin S et al. · Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Added to ASH registry: 2026-05-28
Chronic Thromboembolic Pulmonary Hypertension Medical Management.
Logue R et al. · Methodist DeBakey cardiovascular journal
Added to ASH registry: 2026-05-28
Ciraparantag, an anticoagulant reversal drug: mechanism of action, pharmacokinetics, and reversal of anticoagulants.
Ansell et al. · Blood
Added to ASH registry: 2026-05-28
Clinical Utility of Subcutaneous Factor VIII Replacement Therapies in Hemophilia A: A Review of the Evidence.
Dargaud Y et al. · Journal of blood medicine
Added to ASH registry: 2026-05-28
Coagulopathy and sepsis: Pathophysiology, clinical manifestations and treatment.
Giustozzi et al. · Blood reviews
Added to ASH registry: 2026-05-28
Comparison of the efficacy of rivaroxaban and dabigatran etexilate in preventing venous thrombosis after arthroplasty: A protocol of randomized controlled trial
Song et al. · Medicine
Added to ASH registry: 2026-05-28
Comparison of ultrasound-accelerated versus conventional catheter-directed thrombolysis for deep vein thrombosis: A systematic review and meta-analysis.
Farrokhi M et al. · Vascular
Added to ASH registry: 2026-05-28
Comprehensive review of the impact of direct oral anticoagulants on thrombophilia diagnostic tests: Practical recommendations for the laboratory
Siriez et al. · International journal of laboratory hematology
Added to ASH registry: 2026-05-28
Consensus of free flap complications: Using a nomenclature paradigm in microvascular head and neck reconstruction.
Mady et al. · Head & neck
Added to ASH registry: 2026-05-28
COVID-19-related laboratory coagulation findings.
Devreese · International journal of laboratory hematology
Added to ASH registry: 2026-05-28
Current Opinion on the use of Direct Oral Anticoagulants for the Prophylaxis of Venous Thromboembolism among Medical Inpatients
Lee et al. · Therapeutics and clinical risk management
Added to ASH registry: 2026-05-28
Current Practice of Percutaneous Coronary Intervention in Patients With Coagulation Disorders.
El Khoury M et al. · Cureus
Added to ASH registry: 2026-05-28
Dabigatran Etexilate Induces Cytotoxicity in Rat Gastric Epithelial Cell Line via Mitochondrial Reactive Oxygen Species Production
Kurokawa et al. · Cells
Added to ASH registry: 2026-05-28
Dabigatran Reversal With Idarucizumab and In-Hospital Mortality in Intracranial Hemorrhage: A Systematic Review of Real-Life Data From Case Reports and Case Series.
Frol et al. · Frontiers in neurology
Added to ASH registry: 2026-05-28
Dabigatran Reversal With Idarucizumab in Patients Requiring Urgent Surgery: A Subanalysis of the RE-VERSE AD Study
Levy et al. · Annals of surgery
Added to ASH registry: 2026-05-28
Dabigatran reversal with idarucizumab prior to lung transplantation.
Harano et al. · Clinical transplantation
Added to ASH registry: 2026-05-28
Diagnosis and Management of Transient Ischemic Attack and Acute Ischemic Stroke: A Review.
Mendelson et al. · JAMA
Added to ASH registry: 2026-05-28
Diagnosis and treatment of disseminated intravascular coagulation in COVID-19 patients: a scoping review.
Mori et al. · International journal of hematology
Added to ASH registry: 2026-05-28
Direct Oral Anticoagulants Compared With Dalteparin for Treatment of Cancer-Associated Thrombosis: A Living, Interactive Systematic Review and Network Meta-analysis.
Riaz IB et al. · Mayo Clinic proceedings
Added to ASH registry: 2026-05-28
Direct oral anticoagulants versus warfarin in patients with single or double antibody-positive antiphospholipid syndrome.
Williams B et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Disseminated intravascular coagulation: epidemiology, biomarkers, and management.
Adelborg et al. · British journal of haematology
Added to ASH registry: 2026-05-28
Effects of argatroban therapy for stroke patients: A meta-analysis
Hou et al. · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Added to ASH registry: 2026-05-28
Effects of concomitant administration of anticancer agents and apixaban or dalteparin on recurrence and bleeding in patients with cancer-associated venous thromboembolism.
Verso M et al. · European journal of cancer (Oxford, England : 1990)
Added to ASH registry: 2026-05-28
Efficacy and Safety of Bivalirudin During Percutaneous Coronary Intervention in Chronic Total Occlusion: A Retrospective Study
Zhang et al. · Clinical therapeutics
Added to ASH registry: 2026-05-28
Efficacy of 4-Factor Prothrombin Complex Concentrates in Factor Xa Inhibitor-Associated Intracranial Bleeding
Korobey et al. · Neurocritical care
Added to ASH registry: 2026-05-28
Endovascular Therapy Versus Anticoagulation for Treatment of Cerebral Venous Sinus Thrombosis: A Meta-Analysis.
Xu et al. · The neurologist
Added to ASH registry: 2026-05-28
Endovascular Treatment for Lower Extremity Deep Vein Thrombosis: An Overview.
Kim KA et al. · Korean journal of radiology
Added to ASH registry: 2026-05-28
ESO guideline for the management of extracranial and intracranial artery dissection.
Debette et al. · European stroke journal
Added to ASH registry: 2026-05-28
European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke.
Berge E et al. · European stroke journal
Added to ASH registry: 2026-05-28
Extended duration venous thromboembolism prophylaxis with betrixaban for patients re-admitted with venous thromboembolism
Fahmy et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Extended Thromboprophylaxis With Betrixaban or Rivaroxaban for Acutely Ill Hospitalized Medical Patients: Meta-Analysis of Prespecified Subgroups
Jamil et al. · Critical pathways in cardiology
Added to ASH registry: 2026-05-28
Extracorporeal Membrane Oxygenation Complications in Heparin- and Bivalirudin-Treated Patients.
Giuliano et al. · Critical care explorations
Added to ASH registry: 2026-05-28
Factor VIII replacement prophylaxis in patients with hemophilia A transitioning to adults: a systematic literature review.
Sun J et al. · Orphanet journal of rare diseases
Added to ASH registry: 2026-05-28
Factor Xa inhibitor for venous thromboembolism management in patient with cancer: a systematic review and meta-analysis
Nugroho et al. · F1000Research
Added to ASH registry: 2026-05-28
Factor XII(a) inhibitors: a review of the patent literature
Kalinin et al. · Expert opinion on therapeutic patents
Added to ASH registry: 2026-05-28
Fibrinogen and Fibrin.
Litvinov et al. · Sub-cellular biochemistry
Added to ASH registry: 2026-05-28
GFHT proposals on the practical use of argatroban - With specifics regarding vaccine-induced immune thrombotic thrombocytopaenia (VITT)
Siguret V et al. · Anaesthesia, critical care & pain medicine
Added to ASH registry: 2026-05-28
Heparin Resistance - Clinical Perspectives and Management Strategies.
Levy et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia in extra-corporeal membrane oxygenation: epidemiology, outcomes, and diagnostic challenges.
Zaaqoq et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia: pathophysiology, diagnosis and treatment.
Hvas et al. · Expert review of hematology
Added to ASH registry: 2026-05-28
Hirudin prevents vascular endothelial cell apoptosis and permeability enhancement induced by the serum from rat with chronic renal failure through inhibiting RhoA/ROCK signaling pathway
Chen et al. · Drug development research
Added to ASH registry: 2026-05-28
Idarucizumab Reversal of Dabigatran in Patients with Acute Ischemic Stroke and Intracranial Hemorrhage: Comparison with Non-idarucizumab-Treated Patients
Frol et al. · CNS drugs
Added to ASH registry: 2026-05-28
Impact of an oral anticoagulation self-monitoring and self-management program in patients with mechanical heart valve prosthesis.
Blanch et al. · Journal of comparative effectiveness research
Added to ASH registry: 2026-05-28
Impact of Dabigatran Treatment on Rotation Thromboelastometry
Sokol et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Improved efficacy/safety profile of factor XIa inhibitor BMS-724296 versus factor Xa inhibitor apixaban and thrombin inhibitor dabigatran in cynomolgus monkeys
Wong et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Increased intracranial hemorrhage of mechanical thrombectomy in acute ischemic stroke patients with atrial fibrillation.
Huang et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Intracerebral Hemorrhage.
Nobleza · Continuum (Minneapolis, Minn.)
Added to ASH registry: 2026-05-28
Intravenous Thrombolysis After Dabigatran Reversal by Idarucizumab: A Systematic Review of the Literature.
Frol et al. · Frontiers in neurology
Added to ASH registry: 2026-05-28
Introduction of a thrombin sensor based on its interaction with dabigatran as an oral direct thrombin inhibitor
Paimard et al. · Materials science & engineering. C, Materials for biological applications
Added to ASH registry: 2026-05-28
Investigation of Poor Solubility of a Salt-Cocrystal Hydrate: A Case Study of the Common-Ion Effect in Betrixaban, an Anticoagulant Drug
Devarapalli et al. · Molecular pharmaceutics
Added to ASH registry: 2026-05-28
Lignosulfonic Acid Sodium Is a Noncompetitive Inhibitor of Human Factor XIa
Kar et al. · Pharmaceuticals (Basel, Switzerland)
Added to ASH registry: 2026-05-28
Low-dose thrombolysis for submassive pulmonary embolism.
Yilmaz ES et al. · Journal of investigative medicine : the official publication of the American Federation for Clinical Research
Added to ASH registry: 2026-05-28
Management of Disseminated Intravascular Coagulation in Acute Leukemias.
Ten Cate et al. · Hamostaseologie
Added to ASH registry: 2026-05-28
Management of Life-Threatening Bleeding in Patients With Mechanical Heart Valves.
Huda et al. · Cureus
Added to ASH registry: 2026-05-28
Mechanical heart valve thrombosis during pregnancy under nonwarfarin anticoagulation therapy: Twocase report and literature review.
Huang et al. · Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Added to ASH registry: 2026-05-28
Microscale Parallel Synthesis of Acylated Aminotriazoles Enabling the Development of Factor XIIa and Thrombin Inhibitors
Platte et al. · ChemMedChem
Added to ASH registry: 2026-05-28
Monitoring and Dosing of Argatroban in a Patient With Antiphospholipid Syndrome
Dooling et al. · Hospital pharmacy
Added to ASH registry: 2026-05-28
New Internet-Based Warfarin Anticoagulation Management Approach After Mechanical Heart Valve Replacement: Prospective, Multicenter, Randomized Controlled Trial.
Zhu et al. · Journal of medical Internet research
Added to ASH registry: 2026-05-28
Optimization and Validation of a Facile RP-HPLC Method for Determination of Betrixaban and Lercanidipine in Pharmaceutical and Biological Matrices
ElMasry et al. · Journal of chromatographic science
Added to ASH registry: 2026-05-28
Outcomes in Head and Neck Free Flap Reconstruction Among Patients With a History of Venous Thromboembolism.
Crippen et al. · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Added to ASH registry: 2026-05-28
P-selectin expression assay in a repeatedly serotonin-release assay-negative patient with heparin-induced thrombocytopenia.
Arora et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Pediatric cerebral sinus venous thrombosis: clinical characterization of a Portuguese cohort.
Rodrigues et al. · Acta neurologica Belgica
Added to ASH registry: 2026-05-28
Periprocedural anticoagulation in the uninterrupted edoxaban vs. vitamin K antagonists for ablation of atrial fibrillation (ELIMINATE-AF) trial
Hohnloser et al. · Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Added to ASH registry: 2026-05-28
Personalizing the decision of dabigatran versus warfarin in atrial fibrillation: A secondary analysis of the Randomized Evaluation of Long-term anticoagulation therapY (RE-LY) trial.
Reinhardt et al. · PloS one
Added to ASH registry: 2026-05-28
Pharmacogenetics of Direct Oral Anticoagulants: A Systematic Review
Raymond et al. · Journal of personalized medicine
Added to ASH registry: 2026-05-28
Portal Vein Thrombosis in Cirrhosis.
Shukla et al. · Journal of clinical and experimental hepatology
Added to ASH registry: 2026-05-28
Portal vein thrombosis: an overview of current treatment options.
Galante et al. · Acta gastro-enterologica Belgica
Added to ASH registry: 2026-05-28
Post-TKA abelacimab reduced VTE at 8 to 12 d compared with enoxaparin
Dunn. · Annals of internal medicine
Added to ASH registry: 2026-05-28
Potent Cyclic Peptide Inhibitors of FXIIa Discovered by mRNA Display with Genetic Code Reprogramming
Ford DJ et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Prolongation of clot lysis time by a direct thrombin inhibitor melagatran mediated by paradoxical enhancement of thrombin generation: comparison with a direct factor Xa inhibitor edoxaban
Morishima et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Prothrombin complex concentrates and andexanet for management of direct factor Xa inhibitor related bleeding: a meta-analysis
Luo et al. · European review for medical and pharmacological sciences
Added to ASH registry: 2026-05-28
Quantitative prediction of P-glycoprotein-mediated drug-drug interactions and intestinal absorption using humanized mice
Miyake et al. · British journal of pharmacology
Added to ASH registry: 2026-05-28
Randomized Trial Comparing Standard Versus Ultrasound-Assisted Thrombolysis for Submassive Pulmonary Embolism: The SUNSET sPE Trial.
Avgerinos ED et al. · JACC. Cardiovascular interventions
Added to ASH registry: 2026-05-28
Ranking the efficacy of anticoagulants for the prevention of venous thromboembolism after total hip or knee arthroplasty: A systematic review and a network meta-analysis
Feng et al. · Pharmacological research
Added to ASH registry: 2026-05-28
Reduced-Dose Intravenous Thrombolysis for Acute Intermediate-High-risk Pulmonary Embolism: Rationale and Design of the Pulmonary Embolism International THrOmbolysis (PEITHO)-3 trial.
Sanchez O et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Retrospective Analysis of the Effectiveness of a Reduced Dose of Idarucizumab in Dabigatran Reversal.
Stone et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Reversal of direct oral anticoagulants: Highlights from the Anticoagulation Forum guideline
Gorr et al. · Cleveland Clinic journal of medicine
Added to ASH registry: 2026-05-28
Risk Stratification after an Acute Coronary Syndrome: Significance of Antithrombotic Therapy.
Brazhnik et al. · Journal of clinical medicine
Added to ASH registry: 2026-05-28
Rivaroxaban for the treatment of cerebral venous thrombosis
Esmaeili et al. · BMC neurology
Added to ASH registry: 2026-05-28
Role of Direct Oral Anticoagulation Agents as Thromboprophylaxis in Antiphospholipid Syndrome.
Arora S et al. · Cureus
Added to ASH registry: 2026-05-28
SARS-CoV-2 vaccine-induced immune thrombotic thrombocytopenia treated with immunoglobulin and argatroban
Guetl et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
Screening of the Promising Direct Thrombin Inhibitors from Haematophagous Organisms. Part I: Recombinant Analogues and Their Antithrombotic Activity In Vitro.
Kostromina MA et al. · Biomedicines
Added to ASH registry: 2026-05-28
Selection and in vitro and in vivo characterization of a Kunitz protease inhibitor domain of protease nexin 2 variant that inhibits factor XIa without inhibiting plasmin
EltringhamSmith et al. · Journal of biotechnology
Added to ASH registry: 2026-05-28
Splanchnic vein thrombosis: Clinical manifestations, risk factors, management, and outcomes.
Kawata et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant
Hamada et al. · Frontiers in cardiovascular medicine
Added to ASH registry: 2026-05-28
Strategies for the prevention and treatment of bleeding in patients treated with dabigatran: an update
Xu et al. · Expert opinion on drug metabolism & toxicology
Added to ASH registry: 2026-05-28
Structure of Blood Coagulation Factor VIII in Complex With an Anti-C2 Domain Non-Classical, Pathogenic Antibody Inhibitor
Ronayne et al. · Frontiers in immunology
Added to ASH registry: 2026-05-28
Structure-function of anticoagulant TIX-5, the inhibitor of factor Xa-mediated FV activation.
Maag et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
The Clinical Significance of Drug-Food Interactions of Direct Oral Anticoagulants.
Grześk G et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-28
The Role of TEG and ROTEM in Damage Control Resuscitation.
Brill et al. · Shock (Augusta, Ga.)
Added to ASH registry: 2026-05-28
The Story of the Fibrin(ogen) αC-Domains: Evolution of Our View on Their Structure and Interactions.
Medved et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Thrombin Inhibition by Argatroban: Potential Therapeutic Benefits in COVID-19
Aliter et al. · Cardiovascular drugs and therapy
Added to ASH registry: 2026-05-28
Time in Therapeutic Range for Bivalirudin Among Pediatric Ventricular Assist Device Recipients
Daugherty et al. · ASAIO journal (American Society for Artificial Internal Organs : 1992)
Added to ASH registry: 2026-05-28
Tissue factor pathway inhibitor upregulates CXCR7 expression and enhances CXCL12-mediated migration in chronic lymphocytic leukemia.
Cui et al. · Scientific reports
Added to ASH registry: 2026-05-28
Treatment of haemophilia: From replacement to gene therapy.
Páramo JA · Medicina clinica
Added to ASH registry: 2026-05-28
Turning Up to Eleven: Factor XI Inhibitors as Novel Agents to Maximize Safety and Maintain Efficacy in Thromboembolic Disease
Cave et al. · Current problems in cardiology
Added to ASH registry: 2026-05-28
Two NF-κB subunits are associated with antimicrobial immunity in Hyriopsis cumingii.
Zhu M et al. · Developmental and comparative immunology
Added to ASH registry: 2026-05-28
Uninterrupted versus interrupted direct oral anticoagulation for catheter ablation of atrial fibrillation: A systematic review and meta-analysis.
Asad ZUA et al. · Journal of cardiovascular electrophysiology
Added to ASH registry: 2026-05-28
Von Willebrand Disease: Current Status of Diagnosis and Management.
Weyand AC et al. · Hematology/oncology clinics of North America
Added to ASH registry: 2026-05-28
WPK5, a Novel Kunitz-Type Peptide from the LeechInhibiting Factor XIa, and Its Loop-Replaced Mutant to Improve Potency.
Zheng YZ et al. · Biomedicines
Added to ASH registry: 2026-05-28
A Conformational Change of Complement C5 Is Required for Thrombin-Mediated Cleavage, Revealed by a Novel Ex Vivo Human Whole Blood Model Preserving Full Thrombin Activity
Nilsson PH et al. · Journal of immunology
Added to ASH registry: 2026-05-27
A phase I, single and continuous dose administration study on the safety, tolerability, and pharmacokinetics of neorudin
Liu Y et al. · Pharmacology research & perspectives
Added to ASH registry: 2026-05-27
A study of the influence of lead pollution on the anticoagulant activity of Whitmania pigra based on pharmacodynamics and metabolomics research
Chen X et al. · Journal of Chromatography B
Added to ASH registry: 2026-05-27
A Wireless Near-Infrared Spectroscopy Device for Flap Monitoring: Proof of Concept in a Porcine Musculocutaneous Flap Model
Wu C et al. · Journal of reconstructive microsurgery
Added to ASH registry: 2026-05-27
Acute kidney injury in patients with acute coronary syndrome undergoing invasive management treated with bivalirudin vs. unfractionated heparin: insights from the MATRIX trial
Landi A et al. · Eur Heart J Acute Cardiovasc Care
Added to ASH registry: 2026-05-27
Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood
Storm BS et al. · Journal of immunology
Added to ASH registry: 2026-05-27
Berlin Heart EXCOR and ACTION post-approval surveillance study report
Zafar F et al. · The Journal of heart and lung transplantation
Added to ASH registry: 2026-05-27
Bivalirudin and sirolimus co-eluting coronary stent: Potential strategy for the prevention of stent thrombosis and restenosis
Sane M et al. · International journal of pharmaceutics
Added to ASH registry: 2026-05-27
Bivalirudin as a Systemic Anticoagulant and Flush Solution Additive for Sequential Mitral and Tricuspid Valve Percutaneous Edge-to-Edge Repair in a Patient With Heparin-Induced Thrombocytopenia
Colbaugh Z et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
Bivalirudin in Venovenous Extracorporeal Membrane Oxygenation: Moving Forward in the Real World
Caridi-Scheible M et al. · Critical care medicine
Added to ASH registry: 2026-05-27
Bivalirudin May Reduce the Need for Red Blood Cell Transfusion in Pediatric Cardiac Patients on Extracorporeal Membrane Oxygenation
Machado DS et al. · ASAIO journal
Added to ASH registry: 2026-05-27
Bivalirudin Versus Heparin Monotherapy in ST-Segment-Elevation Myocardial Infarction
James S et al. · Circ Cardiovasc Interv
Added to ASH registry: 2026-05-27
Comparison of Bivalirudin Versus Heparin for Maintenance Systemic Anticoagulation During Adult and Pediatric Extracorporeal Membrane Oxygenation
Seelhammer TG et al. · Critical care medicine
Added to ASH registry: 2026-05-27
Contemporary device management of cardiogenic shock following acute myocardial infarction
Suleiman T et al. · Heart failure reviews
Added to ASH registry: 2026-05-27
Dose estimation for bivalirudin during pediatric cardiopulmonary bypass
Wolstencroft P et al. · Paediatric anaesthesia
Added to ASH registry: 2026-05-27
Effect of leech-centipede medicine on improving erectile function in diabetes-induced erectile dysfunction rats via PDE5 signalling pathway-related molecules
Wang JS · Pharmaceutical biology
Added to ASH registry: 2026-05-27
Efficacy and safety of next-generation tick transcriptome-derived direct thrombin inhibitors
Koh CY et al. · Nature Communications
Added to ASH registry: 2026-05-27
Engineering a 'three-in-one' hirudin prodrug to reduce bleeding risk: A proof-of-concept study
Zhu Y et al. · Journal of Controlled Release
Added to ASH registry: 2026-05-27
Functional morphology of the suckers and teeth of the medicinal leech Hirudo verbana Carena, 1820 (Annelida; Clitellata; Hirudinida): A scanning electron microscope study
Ayhan H et al. · Microsc Res Tech
Added to ASH registry: 2026-05-27
Impact of CytoSorb on kinetics of vancomycin and bivalirudin in critically ill patients
Scandroglio AM et al. · Artificial organs
Added to ASH registry: 2026-05-27
Improved hemocompatibility by modifying acellular blood vessels with bivalirudin and its biocompatibility evaluation
Du P et al. · J Biomed Mater Res A
Added to ASH registry: 2026-05-27
Incidence, predictors, and outcomes associated with acute kidney injury in patients undergoing transcatheter aortic valve replacement: from the BRAVO-3 randomized trial
Chandrasekhar J et al. · Clinical research in cardiology : official journal of the German Cardiac Society
Added to ASH registry: 2026-05-27
Laboratory Monitoring of Direct Oral Anticoagulants (DOACs)
Dunois C · Biomedicines
Added to ASH registry: 2026-05-27
Management of Heparin-Induced Thrombocytopenia Using Plasmapharesis in Patients Undergoing HeartMate 3 Left Ventricular Assist Device
Naqvi SY et al. · ASAIO journal
Added to ASH registry: 2026-05-27
Microneedle patch-assisted transdermal administration of recombinant hirudin for the treatment of thrombotic diseases
Men Z et al. · International journal of pharmaceutics
Added to ASH registry: 2026-05-27
Nanoencapsulation of leech saliva extract proteins in liposomes as a nanocarrier for inhibiting angiogenesis through targeting VEGFA in the Breast cancer cell line (MCF-7)
Shakouri A et al. · BioImpacts
Added to ASH registry: 2026-05-27
NMR-based structural characterization of a two-disulfide-bonded analogue of the FXIIIa inhibitor tridegin
Schmitz T et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-27
Novel cysteine protease inhibitor derived from the leech: recombinant expression, purification, and characterization
Linhares DDC et al. · Toxins
Added to ASH registry: 2026-05-27
Outcomes of systemic anticoagulation with bivalirudin for Impella 5.0
Fabrizio C et al. · International journal of artificial organs
Added to ASH registry: 2026-05-27
Pediatric Mechanical Circulatory Support: Pathophysiology of Pediatric Hemostasis and Available Options
Giorni C et al. · Frontiers in cardiovascular medicine
Added to ASH registry: 2026-05-27
Pharmacological activities and mechanisms of hirudin and its derivatives — a review
Junren C et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-27
Potent Trivalent Inhibitors of Thrombin through Hybridization of Salivary Sulfopeptides from Hematophagous Arthropods
Agten SM et al. · Angewandte Chemie
Added to ASH registry: 2026-05-27
Practicability of Bivalirudin plus Glycoprotein IIb/IIIa Inhibitors in Patients Undergoing Percutaneous Coronary Intervention: A Meta-Analysis
Li S et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-27
Reperfusion After Fibrinolytic Therapy (RAFT): An open-label, multi-centre, randomised controlled trial of bivalirudin versus heparin in rescue percutaneous coronary intervention
Faour A et al. · PloS one
Added to ASH registry: 2026-05-27
Spontaneous Platelet Aggregation in Blood Is Mediated by FcRIIA Stimulation of Bruton's Tyrosine Kinase
Duan R et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-27
Structure and cleavage pattern of a hyaluronate 3-glycanohydrolase in the glycoside hydrolase 79 family
Huang H et al. · Carbohydrate Polymers
Added to ASH registry: 2026-05-27
Study on the activity of recombinant mutant tissue-type plasminogen activator fused with the C-terminal fragment of hirudin
Ren K et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-27
Superior outcomes with Argatroban for heparin-induced thrombocytopenia: a Bayesian network meta-analysis
Colarossi G et al. · International journal of clinical pharmacy
Added to ASH registry: 2026-05-27
Survey of Practice Pattern in Patients With Heparin-Induced Thrombocytopenia Requiring Cardiopulmonary Bypass
Wanat-Hawthorne A et al. · Anesthesia and analgesia
Added to ASH registry: 2026-05-27
The efficacy and safety of Hirudin plus Aspirin versus Warfarin in the secondary prevention of Cardioembolic Stroke due to Nonvalvular Atrial Fibrillation: A multicenter prospective cohort study
Song CG et al. · International Journal of Medical Sciences
Added to ASH registry: 2026-05-27
Thrombolytic and anticoagulant effects of a recombinant staphylokinase-hirudin fusion protein
Ren K et al. · Thrombosis Research
Added to ASH registry: 2026-05-27
Use of bivalirudin for anticoagulation in pediatric extracorporeal membrane oxygenation (ECMO)
Kaushik S et al. · Perfusion
Added to ASH registry: 2026-05-27
A systematic review on Zhilong Huoxue Tongyu capsule in treating cardiovascular and cerebrovascular diseases: Pharmacological actions, molecular mechanisms and clinical outcomes
Liang P et al. · Journal of ethnopharmacology
Added to ASH registry: 2026-05-26
Nanoencapsulation of leech saliva proteins in liposomes as a nanocarrier for inhibiting angiogenesis through targeting VEGFA in breast cancer
Shakouri A et al. · BioImpacts : BI
Added to ASH registry: 2026-05-26
Effect of hirudin on arterialized venous flap survival in rabbits
Liu J et al. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Added to ASH registry: 2026-03-18
Leech therapy (Hirudo medicinalis) attenuates testicular damages induced by testicular ischemia/reperfusion in an animal model
Davoodi F et al. · BMC veterinary research
Added to ASH registry: 2026-03-18
Bivalirudin vs. Heparin on Radial Artery Thrombosis during Transradial Coronary Intervention: An Optical Coherence Tomography Study
Liu et al. · Journal of interventional cardiology
Added to ASH registry: 2026-05-29
Cost-effectiveness analysis of low-dose direct oral anticoagulant (DOAC) for the prevention of cancer-associated thrombosis in the United States
Li et al. · Cancer
Added to ASH registry: 2026-05-29
Drug-drug interaction (DDI) with direct oral anticoagulant (DOAC) in patients with cancer
Sebuhyan et al. · Journal de medecine vasculaire
Added to ASH registry: 2026-05-29
Effects of atorvastatin combined with bivalirudin on coagulation function, cardiac function, and inflammatory factors of percutaneous coronary intervention in elderly patients with acute myocardial infarction
Ding et al. · Annals of palliative medicine
Added to ASH registry: 2026-05-29
Efficacy and safety of bivalirudin application during primary percutaneous coronary intervention in older patients with acute ST-segment elevation myocardial infarction
Chen et al. · The Journal of international medical research
Added to ASH registry: 2026-05-29
Meta-analysis of bivalirudin versus heparin in transradial coronary interventions
Kheiri et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-29
Myocardial damage after ST-segment elevation myocardial infarction by use of bivalirudin or heparin: a DANAMI-3 substudy
Schoos et al. · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Added to ASH registry: 2026-05-29
Prospective evaluation of drug-drug interactions in ambulatory cancer patients initiated on prophylactic anticoagulation
Ng et al. · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
Added to ASH registry: 2026-05-29
Radial versus femoral and bivalirudin versus unfractionated heparin in vulnerable patients with acute coronary syndromes
Galli et al. · Revista espanola de cardiologia (English ed.)
Added to ASH registry: 2026-05-29
[Anticoagulation for Stroke Prevention in Atrial Fibrillation].
Hohnloser · Deutsche medizinische Wochenschrift (1946)
Added to ASH registry: 2026-05-28
[Antithrombotic Therapy in Patients with Acute Coronary Syndrome and Atrial Fibrillation].
Darius · Deutsche medizinische Wochenschrift (1946)
Added to ASH registry: 2026-05-28
[COVID-19 and stroke].
Wada et al. · Rinsho shinkeigaku = Clinical neurology
Added to ASH registry: 2026-05-28
2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS).
Konstantinides et al. · European heart journal
Added to ASH registry: 2026-05-28
A comprehensive evaluation of apixaban in the treatment of venous thromboembolism
Koehl et al. · Expert review of hematology
Added to ASH registry: 2026-05-28
A phase 2 PK/PD study of andexanet alfa for reversal of rivaroxaban and edoxaban anticoagulation in healthy volunteers
Lu et al. · Blood advances
Added to ASH registry: 2026-05-28
Advances and Application of a Novel Oral Anticoagulant in Specific Populations: Dabigatran Etexilate
Xu et al. · Current drug metabolism
Added to ASH registry: 2026-05-28
Aesthetic functional reconstruction of the mutilated hand: Indications and selection of reconstructive techniques
Hu W et al. · Annales de chirurgie plastique et esthetique
Added to ASH registry: 2026-05-28
Analysis of anticoagulation reversal survey (ARES).
Rowe et al. · Hospital practice (1995)
Added to ASH registry: 2026-05-28
Anticoagulation in Pediatric Extracorporeal Life Support-Time for a More Direct Approach?
Ryerson et al. · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Added to ASH registry: 2026-05-28
Anticoagulation Strategies and Filter Life in COVID-19 Patients Receiving Continuous Renal Replacement Therapy: A Single-Center Experience.
Shankaranarayanan et al. · Clinical journal of the American Society of Nephrology : CJASN
Added to ASH registry: 2026-05-28
Antithrombotic therapy in acute coronary syndrome: undertreatment of elderly?
Muraca et al. · Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace
Added to ASH registry: 2026-05-28
Apixaban and dalteparin in active malignancy-associated venous thromboembolism: The ADAM VTE trial
McBane et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Apixaban and rivaroxaban anti-Xa level utilization and associated bleeding events within an academic health system
Jakowenko et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Apixaban for the Treatment of Venous Thromboembolism Associated with Cancer.
Agnelli G et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Argatroban as Purge Solution in Patients With Heparin-Induced Thrombocytopenia on an Impella Device
Mir et al. · American journal of therapeutics
Added to ASH registry: 2026-05-28
Argatroban dosing requirements in extracorporeal life support and other critically ill populations.
Dingman et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Argatroban therapy for heparin-induced thrombocytopenia in a patient with coronavirus disease 2019
Ogawa et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Association between post-percutaneous coronary intervention bivalirudin infusion and net adverse clinical events: a post hoc analysis of the GLOBAL LEADERS study
Chang et al. · European heart journal. Cardiovascular pharmacotherapy
Added to ASH registry: 2026-05-28
Bivalirudin and Alteplase for Pulmonary Embolism Requiring Veno-Arterial Extracorporeal Membrane Oxygenation in an Adolescent
Machado et al. · The journal of extra-corporeal technology
Added to ASH registry: 2026-05-28
Bivalirudin Versus Heparin During Intervention in Acute Coronary Syndrome: A Systematic Review of Randomized Trials
Bhogal et al. · Cardiovascular & hematological disorders drug targets
Added to ASH registry: 2026-05-28
Bivalirudin versus unfractionated heparin during percutaneous coronary intervention in high-bleeding-risk patients with acute coronary syndrome in contemporary practice
Zhang et al. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Added to ASH registry: 2026-05-28
Bleeding with Apixaban and Dalteparin in Patients with Cancer-Associated Venous Thromboembolism: Results from the Caravaggio Study.
Ageno W et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Cancer-associated venous thromboembolism: Treatment and prevention with rivaroxaban.
Bauersachs et al. · Research and practice in thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Catheter ablation of atrial fibrillation with uninterrupted anticoagulation: a meta-analysis of six randomized controlled trials.
Di Monaco A et al. · Journal of cardiovascular medicine (Hagerstown, Md.)
Added to ASH registry: 2026-05-28
Clinical Outcomes of Bivalirudin Versus Heparin in Elderly Patients Undergoing Percutaneous Coronary Intervention: a Systematic Review and Meta-analysis of Randomized Controlled Trials.
Meng S et al. · Cardiovascular drugs and therapy
Added to ASH registry: 2026-05-28
Coagulation factor XII contributes to hemostasis when activated by soil in wounds.
Juang et al. · Blood advances
Added to ASH registry: 2026-05-28
Comparison of molecular structure and fibrin polymerization between two Bβ-chain N-terminal region fibrinogen variants, Bβp.G45C and Bβp.R74C.
Kaido et al. · International journal of hematology
Added to ASH registry: 2026-05-28
Concentrations of dabigatran administered after acute ischemic stroke
Wada et al. · Journal of the neurological sciences
Added to ASH registry: 2026-05-28
Contemporary Management of Acute Pulmonary Embolism.
Tan et al. · Seminars in thoracic and cardiovascular surgery
Added to ASH registry: 2026-05-28
Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs
Wilbs et al. · Nature communications
Added to ASH registry: 2026-05-28
Dabigatran Level Before Reversal Can Predict Hemostatic Effectiveness of Idarucizumab in a Real-World Setting.
Gendron et al. · Frontiers in medicine
Added to ASH registry: 2026-05-28
Dabigatran-induced esophagitis: A case report
Zhou et al. · Medicine
Added to ASH registry: 2026-05-28
Diagnosis and Treatment of Lower Extremity Venous Thromboembolism: A Review.
Chopard et al. · JAMA
Added to ASH registry: 2026-05-28
Direct Oral Anticoagulant Use: A Practical Guide to Common Clinical Challenges.
Chen A et al. · Journal of the American Heart Association
Added to ASH registry: 2026-05-28
Direct oral anticoagulants: evidence and unresolved issues
Chan et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
Discovery of Benzyl Tetraphosphonate Derivative as Inhibitor of Human Factor Xia
Kar et al. · ChemistryOpen
Added to ASH registry: 2026-05-28
Early thromboelastography in acute traumatic coagulopathy: an observational study focusing on pre-hospital trauma care.
Spasiano et al. · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Added to ASH registry: 2026-05-28
Effect of Bisoprolol on the Level of Dabigatran
Nehaj et al. · American journal of therapeutics
Added to ASH registry: 2026-05-28
Efficacy and safety of bivalirudin vs heparin in patients with coronary heart disease undergoing percutaneous coronary intervention: A meta-analysis of randomized controlled trials
Liu et al. · Medicine
Added to ASH registry: 2026-05-28
Enhanced anticoagulant activity of hirudin-i analogue co-expressed with arylsulfotransferase in periplasm of E. coli BL21(DE3)
Rai et al. · Journal of biotechnology
Added to ASH registry: 2026-05-28
EP-7041, a Factor XIa Inhibitor as a Potential Antithrombotic Strategy in Extracorporeal Membrane Oxygenation: A Brief Report
Pollack et al. · Critical care explorations
Added to ASH registry: 2026-05-28
Evaluation of intravenous direct thrombin inhibitor monitoring tests: Correlation with plasma concentrations and clinical outcomes in hospitalized patients
Beyer et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Evaluation of oral factor Xa inhibitor-associated extracranial bleeding reversal with andexanet alfa
Nederpelt et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Extended Thromboprophylaxis for Medical Patients
Dalen et al. · The American journal of medicine
Added to ASH registry: 2026-05-28
Factor Xa Inhibitor-Related Intracranial Hemorrhage: Results From a Multicenter, Observational Cohort Receiving Prothrombin Complex Concentrates
Panos et al. · Circulation
Added to ASH registry: 2026-05-28
Factor Xa Inhibitor, Rivaroxaban, Regulates the Burden of Atrial Fibrillation and Ventricular Premature Captures
Chin et al. · American journal of therapeutics
Added to ASH registry: 2026-05-28
Factor XII/XIIa inhibitors: Their discovery, development, and potential indications
Davoine et al. · European journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Fibrinogen Glycation and Presence of Glucose Impair Fibrin Polymerization-An In Vitro Study of Isolated Fibrinogen and Plasma from Patients with Diabetes Mellitus.
Luzak et al. · Biomolecules
Added to ASH registry: 2026-05-28
Heparin vs bivalirudin anticoagulation for extracorporeal membrane oxygenation.
Kaseer et al. · Journal of cardiac surgery
Added to ASH registry: 2026-05-28
High-Throughput Docking and Molecular Dynamics Simulations towards the Identification of Potential Inhibitors against Human Coagulation Factor XIIa
Xu et al. · Computational and mathematical methods in medicine
Added to ASH registry: 2026-05-28
Idarucizumab for dabigatran reversal in daily clinical practice: A case series
Vene et al. · European journal of anaesthesiology
Added to ASH registry: 2026-05-28
Idarucizumab for Emergency Reversal of Anticoagulant Effects of Dabigatran: Interim Results of a Japanese Post-Marketing Surveillance Study.
Yasaka et al. · Cardiology and therapy
Added to ASH registry: 2026-05-28
Impact of posttranslational modifications on atomistic structure of fibrinogen.
Sovová Ž et al. · PloS one
Added to ASH registry: 2026-05-28
Individuating Possibly Repurposable Drugs and Drug Targets for COVID-19 Treatment Through Hypothesis-Driven Systems Medicine Using CoVex
Matschinske et al. · Assay and drug development technologies
Added to ASH registry: 2026-05-28
Influence of Direct Thrombin Inhibitor and Low Molecular Weight Heparin on Platelet Function in Patients with Coronary Artery Disease: A Prospective Interventional Trial
Arantes et al. · Advances in therapy
Added to ASH registry: 2026-05-28
Inhibitory effects of dabigatran etexilate, a direct thrombin inhibitor, on osteoclasts and osteoblasts
Rocha et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Laboratory monitoring of rivaroxaban in Chinese patients with deep venous thrombosis: a preliminary study
Li et al. · BMC pharmacology & toxicology
Added to ASH registry: 2026-05-28
Lung transplantation using argatroban in severe heparin-induced thrombocytopenia during extracorporeal membrane oxygenation: a case series
Lee et al. · General thoracic and cardiovascular surgery
Added to ASH registry: 2026-05-28
Massive transfusion protocol in adult trauma population.
Meneses et al. · The American journal of emergency medicine
Added to ASH registry: 2026-05-28
Mechanical thrombectomy for acute ischaemic stroke during therapeutic anticoagulation: long-term outcomes.
Nowak et al. · Neurologia i neurochirurgia polska
Added to ASH registry: 2026-05-28
Medical Management for Secondary Stroke Prevention.
Kim · Continuum (Minneapolis, Minn.)
Added to ASH registry: 2026-05-28
Neonatal thrombosis.
Makatsariya A et al. · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Added to ASH registry: 2026-05-28
Novel factor Xa inhibitor, maslinic acid, with antiplatelet aggregation activity
Kim et al. · Journal of cellular physiology
Added to ASH registry: 2026-05-28
Outcomes of Cardiac Catheterization in Patients With Atrial Fibrillation on Anticoagulation in Contemporary in Practice: An Analysis of the ORBIT II Registry.
Sherwood et al. · Circulation. Cardiovascular interventions
Added to ASH registry: 2026-05-28
Oxidation of betrixaban to yield N-nitrosodimethylamine by water disinfectants
Jasemizad et al. · Water research
Added to ASH registry: 2026-05-28
Pediatric trauma venous thromboembolism prediction algorithm outperforms current anticoagulation prophylaxis guidelines: a pilot study.
Cunningham AJ et al. · Pediatric surgery international
Added to ASH registry: 2026-05-28
Perfusion dynamics in pedicled and free tissue reconstruction: Infrared thermography and laser fluorescence video angiography
Shokri T et al. · American journal of otolaryngology
Added to ASH registry: 2026-05-28
Perioperative management of anticoagulation
Talari G et al. · Hospital practice (1995)
Added to ASH registry: 2026-05-28
Predictors of preprocedural direct oral anticoagulant levels in patients having an elective surgery or procedure.
Shaw JR et al. · Blood advances
Added to ASH registry: 2026-05-28
Primary prevention of venous thromboembolism with apixaban for multiple myeloma patients receiving immunomodulatory agents
Cornell et al. · British journal of haematology
Added to ASH registry: 2026-05-28
Prophylaxis for hemophilia A without inhibitors: treatment options and considerations.
Valentino LA et al. · Expert review of hematology
Added to ASH registry: 2026-05-28
Pulmonary embolism: update on management and controversies.
Duffett et al. · BMJ (Clinical research ed.)
Added to ASH registry: 2026-05-28
Pulmonary Hypertension: A Brief Guide for Clinicians.
Mandras SA et al. · Mayo Clinic proceedings
Added to ASH registry: 2026-05-28
Real World Outcomes Associated with Idarucizumab: Population-Based Retrospective Cohort Study.
Singh et al. · American journal of cardiovascular drugs : drugs, devices, and other interventions
Added to ASH registry: 2026-05-28
Real-world experience with reversal of dabigatran by idarucizumab.
Haastrup et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Recurrent venous thromboembolism during anticoagulation with edoxaban or warfarin: A post hoc analysis of the Hokusai-VTE trial
Eichinger et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Regulation of Thrombin Activity with Ultrasmall Nanoparticles: Effects of Surface Chemistry.
Lira AL et al. · Langmuir : the ACS journal of surfaces and colloids
Added to ASH registry: 2026-05-28
Response to: Time frame for withholding direct thrombin inhibitor therapy before neurosurgery
Pennington et al. · Clinical neurology and neurosurgery
Added to ASH registry: 2026-05-28
Riociguat in the Treatment of Chronic Thromboembolic Pulmonary Hypertension: An Evidence-Based Review of Its Place in Therapy.
Donaldson S et al. · Core evidence
Added to ASH registry: 2026-05-28
Rivaroxaban as an Alternative Agent for Heparin-Induced Thrombocytopenia
Farasatinasab et al. · Journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Rivaroxaban for treatment of pediatric venous thromboembolism. An Einstein-Jr phase 3 dose-exposure-response evaluation.
Young G et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Role of Factor XIa and Plasma Kallikrein in Arterial and Venous Thrombosis
Visser et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Safety and efficacy of rivaroxaban in pediatric cerebral venous thrombosis (EINSTEIN-Jr CVT).
Connor et al. · Blood advances
Added to ASH registry: 2026-05-28
Safety of Catheter Ablation of Atrial Fibrillation Under Uninterrupted Rivaroxaban Use.
Silva MA et al. · Arquivos brasileiros de cardiologia
Added to ASH registry: 2026-05-28
Structure-Based Design of FXIIIa-Blockers: Addressing a Transient Hydrophobic Pocket in the Active Site of FXIIIa
Stieler et al. · ChemMedChem
Added to ASH registry: 2026-05-28
Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates
Calisto BM et al. · Cell chemical biology
Added to ASH registry: 2026-05-28
Synthesis, Docking, and In Vitro Anticoagulant Activity Assay of Hybrid Derivatives of Pyrrolo[3,2,1-ij]Quinolin-2(1H)-one as New Inhibitors of Factor Xa and Factor XIa
Novichikhina et al. · Molecules (Basel, Switzerland)
Added to ASH registry: 2026-05-28
Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia
Zhao XY et al. · Nature communications
Added to ASH registry: 2026-05-28
Tenecteplase Thrombolysis for Acute Ischemic Stroke.
Warach SJ et al. · Stroke
Added to ASH registry: 2026-05-28
The Effects of Dextran on Postoperative Thrombosis and Hemodilution in Microvascular Head and Neck Reconstruction.
Filipan et al. · Annals of plastic surgery
Added to ASH registry: 2026-05-28
The impact of rivaroxaban on primary hemostasis in patients with venous thrombosis
Schultz et al. · Platelets
Added to ASH registry: 2026-05-28
The protein C activator AB002 rapidly interrupts thrombus development in baboons.
Tucker et al. · Blood
Added to ASH registry: 2026-05-28
The Research Progress of Direct Thrombin Inhibitors
Sun et al. · Mini reviews in medicinal chemistry
Added to ASH registry: 2026-05-28
The Use of Indocyanine Green Angiography for Cosmetic and Reconstructive Assessment in the Head and Neck
Abdelwahab M et al. · Facial plastic surgery : FPS
Added to ASH registry: 2026-05-28
Therapeutic plasma exchange and intravenous immune globulin in the treatment of heparin-induced thrombocytopenia: A systematic review
Onuoha et al. · Transfusion
Added to ASH registry: 2026-05-28
Thrombin alters the synthesis and processing of CYR61/CCN1 in human corneal stromal fibroblasts and myofibroblasts through multiple distinct mechanisms
Andreae et al. · Molecular vision
Added to ASH registry: 2026-05-28
Thromboelastography and rotational thromboelastometry in bleeding patients with coagulopathy: Practice management guideline from the Eastern Association for the Surgery of Trauma.
Bugaev et al. · The journal of trauma and acute care surgery
Added to ASH registry: 2026-05-28
Thromboembolism Prophylaxis for Patients Discharged From the Hospital: Easier Said Than Done
Goldhaber · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
Thrombolysis in acute pulmonary embolism.
Bottega et al. · Revista da Associacao Medica Brasileira (1992)
Added to ASH registry: 2026-05-28
Thrombosis and bleedings in a cohort of cancer patients treated with apixaban for venous thromboembolism.
Hannevik et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Time frame for withholding direct thrombin inhibitor therapy before neurosurgery
Gharaei et al. · Clinical neurology and neurosurgery
Added to ASH registry: 2026-05-28
Treatment of venous thromboembolism in pediatric patients.
Witmer C et al. · Blood
Added to ASH registry: 2026-05-28
Treatment strategies for patients with atrial fibrillation and anticoagulant-associated intracranial hemorrhage: an overview of the pharmacotherapy.
Rivera-Caravaca et al. · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-28
Trial of Rivaroxaban in AntiPhospholipid Syndrome (TRAPS): Two-year outcomes after the study closure.
Pengo V et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Ultrasound Aspects and Recanalization Rates in Patients with Lower-Limb Deep Venous Thrombosis Treated with Rivaroxaban
de et al. · Annals of vascular surgery
Added to ASH registry: 2026-05-28
Uninterrupted anticoagulation during catheter ablation for atrial fibrillation: no difference in major bleeding and stroke between direct oral anticoagulants and vitamin K antagonists in an updated meta-analysis of randomised controlled trials.
Brockmeyer M et al. · Acta cardiologica
Added to ASH registry: 2026-05-28
Uninterrupted Direct Oral Anticoagulants in Atrial Fibrillation Catheter Ablation: Ready for Prime Time.
Cardoso R et al. · Arquivos brasileiros de cardiologia
Added to ASH registry: 2026-05-28
VE-1902-A direct thrombin inhibitor with reversible covalent mechanism of action shows efficacy with reduced bleeding in rodent models of thrombosis
Sivaraja et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Viscoelastic haemostatic assay augmented protocols for major trauma haemorrhage (ITACTIC): a randomized, controlled trial.
Baksaas-Aasen et al. · Intensive care medicine
Added to ASH registry: 2026-05-28
VITPOR AI, A Coagulation Factor XIIa Inhibitor from Porphyra yezoensis: In Vivo Mode of Action and Assessment of Platelet Function Analysis
L et al. · Protein and peptide letters
Added to ASH registry: 2026-05-28
von Willebrand disease: Diagnosis and treatment, treatment of women, and genomic approach to diagnosis.
Laffan M et al. · Haemophilia : the official journal of the World Federation of Hemophilia
Added to ASH registry: 2026-05-28
What is the appropriate anticoagulation strategy for thrombotic antiphospholipid syndrome?
Arachchillage DRJ et al. · British journal of haematology
Added to ASH registry: 2026-05-28
A look into stent-related thrombus-burden: Bivalirudin versus heparin
Rajagopalan P et al. · Catheterization and Cardiovascular Interventions
Added to ASH registry: 2026-05-27
A novel thrombin inhibitory peptide discovered from leech using affinity chromatography combined with ultra-high performance liquid chromatography-high resolution mass spectroscopy
Huang Q et al. · J Chromatogr B Analyt Technol Biomed Life Sci
Added to ASH registry: 2026-05-27
A Review of Bivalirudin for Pediatric and Adult Mechanical Circulatory Support
Taylor T et al. · American journal of cardiovascular drugs
Added to ASH registry: 2026-05-27
Acute administration of metformin prior to cardiac ischemia/reperfusion injury protects brain injury
Leech T et al. · European journal of pharmacology
Added to ASH registry: 2026-05-27
Avoiding ambient air in test tubes during incubations of human whole-blood minimizes complement background activation
Storm BS et al. · Journal of immunological methods
Added to ASH registry: 2026-05-27
Bivalirudin Experience in a Heterogeneous Ventricular Assist Device Population
Bates A et al. · ASAIO journal
Added to ASH registry: 2026-05-27
Bivalirudin for maintenance anticoagulation during venovenous extracorporeal membrane oxygenation for COVID-19
Seelhammer TG et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
Bivalirudin Use During Pulmonary Vein Isolation in a Patient With Heparin-Induced Thrombocytopenia
Kanjwal K et al. · American Journal of Therapeutics
Added to ASH registry: 2026-05-27
Bivalirudin Versus Heparin Monotherapy in Elderly Patients With Myocardial Infarction: A Prespecified Subgroup Analysis of the VALIDATE-SWEDEHEART Trial
Wester A et al. · Circ Cardiovasc Interv
Added to ASH registry: 2026-05-27
Challenges in Maintaining the Hemostatic Balance in Children Undergoing Extracorporeal Membrane Oxygenation: A Systematic Literature Review
Drop JG et al. · Frontiers in pediatrics
Added to ASH registry: 2026-05-27
Characterisation of antithrombin-dependent anticoagulants through clot waveform analysis to potentially distinguish them from antithrombin-independent inhibitors targeting activated coagulation factors
Wakui M et al. · Journal of clinical pathology
Added to ASH registry: 2026-05-27
Choice of access site and type of anticoagulant in acute coronary syndromes with advanced Killip class or out-of-hospital cardiac arrest
Gargiulo G et al. · Rev Esp Cardiol (Engl Ed)
Added to ASH registry: 2026-05-27
Clinical Applications and Benefits of Using Closed-Incision Negative Pressure Therapy for Incision and Surrounding Soft Tissue Management: A Novel Approach for Comorbid Wounds
Gomez TW et al. · Cureus
Added to ASH registry: 2026-05-27
Complement Inhibitors Block Complement C3 Opsonization and Improve Targeting Selectivity of Nanoparticles in Blood
Gaikwad H et al. · Bioconjugate chemistry
Added to ASH registry: 2026-05-27
Coronary thrombosis due to heparin-induced thrombocytopenia after percutaneous coronary intervention: Easy to miss, uneasy to prevent
Mele M et al. · Clinical Case Reports
Added to ASH registry: 2026-05-27
Couplet medicines of leech and centipede granules improve erectile dysfunction via inactivation of the CaSR/PLC/PKC signaling in streptozotocin-induced diabetic rats
Ma JX et al. · Bioscience reports
Added to ASH registry: 2026-05-27
Distinct 3-disulfide-bonded isomers of tridegin differentially inhibit coagulation factor XIIIa
Bäuml CA et al. · European journal of medicinal chemistry
Added to ASH registry: 2026-05-27
Ecarin based coagulation testing
Gosselin RC, Douxfils J · American journal of hematology
Added to ASH registry: 2026-05-27
Effect of leech-centipede medicine on improving erectile function in DIED rats via PKC signalling pathway-related molecules
Wang JS · Journal of ethnopharmacology
Added to ASH registry: 2026-05-27
Effects of Time-Interval since Blood Draw and of Anticoagulation on Platelet Testing (Count, Indices and Impedance Aggregometry): A Systematic Study with Blood from Healthy Volunteers
Hardy M et al. · Journal of clinical medicine
Added to ASH registry: 2026-05-27
Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum
Wang Y et al. · Nature Communications
Added to ASH registry: 2026-05-27
European Medicinal Leeches - New Roles in Modern Medicine
Lemke S et al. · Biomedicines
Added to ASH registry: 2026-05-27
Evaluation of Bivalirudin As an Alternative to Heparin for Systemic Anticoagulation in Pediatric Extracorporeal Membrane Oxygenation
Hamzah M et al. · Pediatric critical care medicine
Added to ASH registry: 2026-05-27
From leeches to interferon: should cytoreduction be prescribed for all patients with polycythemia vera?
Kiladjian JJ · Leukemia
Added to ASH registry: 2026-05-27
High-level constitutive expression of leech hyaluronidase with combined strategies in recombinant Pichia pastoris
Huang H et al. · Appl Microbiol Biotechnol
Added to ASH registry: 2026-05-27
Improving long circulation and procoagulant platelet targeting by engineering of hirudin prodrug
Han H et al. · International journal of pharmaceutics
Added to ASH registry: 2026-05-27
Is anticoagulation with bivalirudin comparable to heparin for pediatric extracorporeal life support? Results from a high-volume center
Schill MR et al. · Artificial organs
Added to ASH registry: 2026-05-27
Metabolomics-based study reveals the effect of lead (Pb) in the culture environment on Whitmania pigra
Luo X et al. · Scientific reports
Added to ASH registry: 2026-05-27
Near infrared spectroscopy; A novel application of INVOS for monitoring muscle only free flaps
Romeo PB et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Added to ASH registry: 2026-05-27
Prospective Exploratory Experience With Bivalirudin Anticoagulation in Pediatric Extracorporeal Membrane Oxygenation
Ryerson LM et al. · Pediatric critical care medicine
Added to ASH registry: 2026-05-27
RGD-hirudin-based low molecular weight peptide prevents blood coagulation via subcutaneous injection
Li YR et al. · Acta Pharmacologica Sinica
Added to ASH registry: 2026-05-27
Safety and efficacy of bivalirudin monotherapy in patients with non-ST-segment elevation acute coronary syndromes with positive biomarkers undergoing percutaneous coronary intervention
Huang X et al. · Coron Artery Dis
Added to ASH registry: 2026-05-27
Successful local use of heparin calcium for congested fingertip replants
Kadota H et al. · Archives of plastic surgery
Added to ASH registry: 2026-05-27
Temperature-controlled molecular weight of hyaluronic acid produced by engineered Bacillus subtilis
Li Y et al. · Biotechnology Letters
Added to ASH registry: 2026-05-27
The Hirudo medicinalis microbiome is a source of new antimicrobial peptides
Grafskaia E et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-27
The importance of the Heart Team evaluation before transcatheter aortic valve replacement: Results from the BRAVO-3 trial
Camaj A et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-27
The Use of Bivalirudin in Pediatric Cardiac Surgery and in the Interventional Cardiology Suite
Goswami D et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
The Use of Bivalirudin in Pediatric Cardiac Surgery and in the Interventional Cardiology Suite
Goswami A et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
Time to Change Theory; Medical Leech from a Molecular Medicine Perspective: Leech Salivary Proteins Playing a Potential Role in Medicine
Shakouri A et al. · Advanced pharmaceutical bulletin
Added to ASH registry: 2026-05-27
Utilization and outcomes of children treated with direct thrombin inhibitors on paracorporeal ventricular assist device support
VanderPluym CJ et al. · ASAIO journal
Added to ASH registry: 2026-05-27
Effect of Unloading Condition on the Healing Process and Effectiveness of Platelet Rich Plasma as a Countermeasure: Study on In Vivo and In Vitro Wound Healing Models
Cialdai F et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-26
Self-regulated hirudin delivery for anticoagulant therapy
Xu X, Huang X, Zhang Y et al. · Science advances
Added to ASH registry: 2026-05-26
Cell-free synthesis of the hirudin variant 1 of the blood-sucking leech Hirudo medicinalis
Wüstenhagen D et al. · Scientific reports
Added to ASH registry: 2026-03-18
Draft genome of the European medicinal leech Hirudo medicinalis (Annelida, Clitellata, Hirudiniformes) with emphasis on anticoagulants
Kvist S et al. · Scientific reports
Added to ASH registry: 2026-03-18
Hirudin or hirudin-like factor - that is the question: insights from the analyses of natural and synthetic HLF variants
Müller C et al. · FEBS letters
Added to ASH registry: 2026-03-18
Non-Occlusive Mesenteric Ischemia Due to Hirudotherapy: A Case Report
Akalın Ç, Ekmen N · Cureus
Added to ASH registry: 2026-03-18
RGD-hirudin-based low molecular weight peptide prevents blood coagulation via subcutaneous injection
Li Y et al. · Acta pharmacologica Sinica
Added to ASH registry: 2026-03-18
The hirudin-like factors HLF3 and HLF4-hidden hirudins of European medicinal leeches
Müller C et al. · Parasitology research
Added to ASH registry: 2026-03-18
Comparison of Clinical Outcomes: Bivalirudin With Transfemoral Access Versus Heparin With Transradial Access in Patients With ST segment Elevation Myocardial Infarction
Mallidi et al. · Critical pathways in cardiology
Added to ASH registry: 2026-05-29
Efficacy and safety of Xa inhibitors for the treatment of cancer-associated venous thromboembolism
Kimpton et al. · Expert opinion on drug safety
Added to ASH registry: 2026-05-29
Is a prolongation of bivalirudin infusion needed in patients with STEMI undergoing percutaneous coronary intervention?
Chen et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-29
Periprocedural Bivalirudin Versus Unfractionated Heparin During Percutaneous Coronary Intervention Following Fibrinolysis for ST-Segment Elevation Myocardial Infarction
Rashid et al. · The Journal of invasive cardiology
Added to ASH registry: 2026-05-29
Response to the letter to the editor: anticoagulant activity of bivalirudin
Laine et al. · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-29
[Argatroban in heparin-induced thrombocytopenia: A survey of prescribing practices and use in France].
Elalamy I et al. · Therapie
Added to ASH registry: 2026-05-28
[Rivaroxaban versus warfarin in high-risk patients with antiphospholipid syndrome].
Hadjiski D · Zeitschrift fur Rheumatologie
Added to ASH registry: 2026-05-28
A Prospective, Single-Arm, Multicenter Trial of Catheter-Directed Mechanical Thrombectomy for Intermediate-Risk Acute Pulmonary Embolism: The FLARE Study.
Tu et al. · JACC. Cardiovascular interventions
Added to ASH registry: 2026-05-28
Acquired platelet function disorders.
Brennan et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Andexanet alfa for reversal of factor Xa inhibitor-associated anticoagulation.
Carpenter et al. · Therapeutic advances in drug safety
Added to ASH registry: 2026-05-28
Andexanet alfa for reversal of factor Xa inhibitors: a critical review of the evidence.
Abdulrehman et al. · Future cardiology
Added to ASH registry: 2026-05-28
Andexanet Alfa for Reversing Factor Xa Inhibition
Sible et al. · Cardiology in review
Added to ASH registry: 2026-05-28
Andexanet alfa for the reversal of factor Xa inhibitors.
Favresse et al. · Expert opinion on biological therapy
Added to ASH registry: 2026-05-28
Andexanet alfa: A Novel Factor Xa Inhibitor Reversal Agent.
Powell et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Andexanet Alfa: A Recombinant Modified Human Factor Xa Protein for Drug Reversal of Rivaroxaban and Apixaban.
Abuan et al. · The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians
Added to ASH registry: 2026-05-28
Anti-Xa Oral Anticoagulant Plasma Concentration Assay in Real Life: Rivaroxaban and Apixaban Quantification in Emergency With LMWH Calibrator
Billoir P et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Anticoagulation in Venous Thromboembolism Prophylaxis in Medically Ill Patients: Potential Impact of NOACs
Knotts et al. · American journal of cardiovascular drugs : drugs, devices, and other interventions
Added to ASH registry: 2026-05-28
Anticoagulation, the Unknown of the Antithrombotic Equation After Stenting of an Acute Coronary Syndrome
Montalescot et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
Antithrombotic therapy after acute coronary syndrome and/or percutaneous coronary intervention in atrial fibrillation: finding the sweet spot.
Lopes et al. · European heart journal
Added to ASH registry: 2026-05-28
Apixaban and Rivaroxaban in Patients With Acute Venous Thromboembolism
Bott-Kitslaar et al. · Mayo Clinic proceedings
Added to ASH registry: 2026-05-28
Apixaban and rivaroxaban in patients with cerebral venous thrombosis
Covut et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Apixaban to Prevent Venous Thromboembolism in Patients with Cancer
Carrier et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Apixaban: A Clinical Pharmacokinetic and Pharmacodynamic Review.
Byon W et al. · Clinical pharmacokinetics
Added to ASH registry: 2026-05-28
Attenuation of type-1 diabetes-induced cardiovascular dysfunctions by direct thrombin inhibitor in rats: a mechanistic study
Bulani et al. · Molecular and cellular biochemistry
Added to ASH registry: 2026-05-28
Bivalirudin in Extracorporeal Life Support: Response and Considerations
Dager et al. · ASAIO journal (American Society for Artificial Internal Organs : 1992)
Added to ASH registry: 2026-05-28
Chronic thromboembolic pulmonary hypertension.
Kim NH et al. · The European respiratory journal
Added to ASH registry: 2026-05-28
Citrullination of fibrinogen by peptidylarginine deiminase 2 impairs fibrin clot structure.
Damiana et al. · Clinica chimica acta; international journal of clinical chemistry
Added to ASH registry: 2026-05-28
Clinical Pharmacology of Oral Anticoagulants in Patients with Kidney Disease
Jain N et al. · Clinical journal of the American Society of Nephrology : CJASN
Added to ASH registry: 2026-05-28
Comparative effectiveness and safety of pharmacological and non-pharmacological interventions for insomnia: an overview of reviews.
Rios et al. · Systematic reviews
Added to ASH registry: 2026-05-28
Comparison of the recanalization rate and postthrombotic syndrome in patients with deep venous thrombosis treated with rivaroxaban or warfarin
de et al. · Surgery
Added to ASH registry: 2026-05-28
Comparison of the Therapeutic Effects of Rivaroxaban Versus Warfarin in Antiphospholipid Syndrome: A Systematic Review.
Khodashahi M et al. · Archives of rheumatology
Added to ASH registry: 2026-05-28
Confidence and Attitudes Toward Osteoarthritis Care Among the Current and Emerging Health Workforce: A Multinational Interprofessional Study.
Briggs et al. · ACR open rheumatology
Added to ASH registry: 2026-05-28
Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial
Lorentz et al. · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-28
Crystal structures of the recombinant β-factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics.
Pathak M et al. · Acta crystallographica. Section D, Structural biology
Added to ASH registry: 2026-05-28
Current Management of Acute Pulmonary Embolism.
Martinez Licha et al. · Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
Added to ASH registry: 2026-05-28
Dabigatran as a Treatment Option for Heparin-Induced Thrombocytopenia
Nasiripour et al. · Journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Dabigatran Monitoring Was Influenced by Thrombin Time Reagent With Different Thrombin Concentrations
Xu et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Dabigatran must be used carefully: literature review and recommendations for management of adverse events
Lin et al. · Drug design, development and therapy
Added to ASH registry: 2026-05-28
Dabigatran reversal by idarucizumab in the setting of intracranial hemorrhage: A systematic review of the literature.
Lu et al. · Clinical neurology and neurosurgery
Added to ASH registry: 2026-05-28
Dabigatran Reversal with Idarucizumab in an Emergency Lumbar Puncture: A Case Report.
Spagnolello et al. · Current drug safety
Added to ASH registry: 2026-05-28
Dabigatran Reversal With Idarucizumab in Patients With Renal Impairment
Eikelboom et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
Dabigatran-induced esophagitis
Kajihara et al. · Cleveland Clinic journal of medicine
Added to ASH registry: 2026-05-28
Diagnosis and management of heparin-induced thrombocytopenia: a consensus statement from the Thrombosis and Haemostasis Society of Australia and New Zealand HIT Writing Group.
Joseph et al. · The Medical journal of Australia
Added to ASH registry: 2026-05-28
Diagnosis and management of sepsis-induced coagulopathy and disseminated intravascular coagulation.
Iba et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Diagnosis of sepsis-induced disseminated intravascular coagulation and coagulopathy.
Iba et al. · Acute medicine & surgery
Added to ASH registry: 2026-05-28
Diagnosis, Treatment and Follow Up of Acute Pulmonary Embolism: Consensus Practice from the PERT Consortium.
Rivera-Lebron et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Direct oral anticoagulants for venous thromboembolism prophylaxis in critically ill patients: where do we go from here?
Bertoletti et al. · Intensive care medicine
Added to ASH registry: 2026-05-28
Direct-Thrombin Inhibitor Utilization in Patients With Heparin-Induced Thrombocytopenia and Undergoing Catheter-Directed Thrombolysis: A Summary of Published Case Reports.
Badreldin et al. · The Journal of cardiovascular nursing
Added to ASH registry: 2026-05-28
Early initiation of a factor Xa inhibitor can attenuate tissue repair and neurorestoration after middle cerebral artery occlusion
Komori et al. · Brain research
Added to ASH registry: 2026-05-28
Edoxaban-based versus vitamin K antagonist-based antithrombotic regimen after successful coronary stenting in patients with atrial fibrillation (ENTRUST-AF PCI): a randomised, open-label, phase 3b trial.
Vranckx et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
Effect of a new inhibitor of factor Xa zifaxaban, on thrombosis in the inferior vena cava in rabbits
Qiu et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Efficacy and Safety of Direct Oral Anticoagulants for Secondary Prevention of Cancer-Associated Thrombosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Prospective Cohort Studies.
Wang Y et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-28
Efficacy of rivaroxaban for pulmonary embolism
Jia et al. · Medicine
Added to ASH registry: 2026-05-28
Enhanced potency of prasugrel on protease-activated receptors following bivalirudin treatment for PCI as compared to clopidogrel.
Kimmelstiel C et al. · Thrombosis research
Added to ASH registry: 2026-05-28
EULAR recommendations for the management of antiphospholipid syndrome in adults.
Tektonidou et al. · Annals of the rheumatic diseases
Added to ASH registry: 2026-05-28
Evidence-Based Minireview: Mortality and thrombosis in patients receiving prothrombin complex concentrates or andexanet alfa for the management of direct oral factor Xa inhibitor-associated major bleeding
Kimpton et al. · Hematology. American Society of Hematology. Education Program
Added to ASH registry: 2026-05-28
Expression and purification of recombinant serine protease domain of human coagulation factor XII in Pichia pastoris
Peng et al. · Bioscience, biotechnology, and biochemistry
Added to ASH registry: 2026-05-28
Factor VIII: Long-established role in haemophilia A and emerging evidence beyond haemostasis.
Samuelson Bannow B et al. · Blood reviews
Added to ASH registry: 2026-05-28
Factor Xa Inhibitory Profile of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban Does Not Fully Reflect Their Biologic Spectrum
Siddiqui et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Heparin Bridging Therapy for Patients on Chronic Oral Anticoagulants in Periprocedural Settings.
Nikolakopoulos I et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Idarucizumab for Dabigatran Reversal in the Management of Patients With Gastrointestinal Bleeding
Van et al. · Circulation
Added to ASH registry: 2026-05-28
Idarucizumab for Dabigatran-Related Gastrointestinal Bleeds
Siegal et al. · Circulation
Added to ASH registry: 2026-05-28
Idarucizumab for Reversal of Dabigatran in Early/Emergency Surgeries: A Case Series.
Peacock et al. · The Journal of emergency medicine
Added to ASH registry: 2026-05-28
Idarucizumab for Reversal of Dabigatran: Single-Center Real-World Experience.
Sheikh-Taha · American journal of cardiovascular drugs : drugs, devices, and other interventions
Added to ASH registry: 2026-05-28
Intravenous thrombolysis in stroke after dabigatran reversal with idarucizumab: case series and systematic review
Giannandrea et al. · Journal of neurology, neurosurgery, and psychiatry
Added to ASH registry: 2026-05-28
Management of direct factor Xa inhibitor-related major bleeding with prothrombin complex concentrate: a meta-analysis
Piran et al. · Blood advances
Added to ASH registry: 2026-05-28
Management of Severe Bleeding in Patients Treated With Oral Anticoagulants: Proceedings Monograph From the Emergency Medicine Cardiac Research and Education Group-International Multidisciplinary Severe Bleeding Consensus Panel October 20, 2018.
Gibler et al. · Critical pathways in cardiology
Added to ASH registry: 2026-05-28
Mechanism and inhibition kinetics of peptide P13 as thrombin inhibitor
Chen F et al. · International journal of biological macromolecules
Added to ASH registry: 2026-05-28
Na-binding modes involved in thrombin's allosteric response as revealed by molecular dynamics simulations, correlation networks and Markov modeling.
Xiao et al. · Physical chemistry chemical physics : PCCP
Added to ASH registry: 2026-05-28
Optimal Antithrombotic Therapy for Patients with STEMI Undergoing PCI at High Risk of Bleeding.
Tu Y et al. · Current atherosclerosis reports
Added to ASH registry: 2026-05-28
Pharmacological Profile of JNJ-64179375: A Novel, Long-Acting Exosite-1 Thrombin Inhibitor
Huang Devine et al. · The Journal of pharmacology and experimental therapeutics
Added to ASH registry: 2026-05-28
Pharmacomechanical Thrombectomy Versus Catheter-Directed Thrombolysis for Iliofemoral Deep Vein Thrombosis: A Meta-Analysis of Clinical Trials.
Tang T et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
PIFA PLUSS P4 Assay for Screening of Heparin-Induced Thrombocytopenia.
Compton et al. · Laboratory medicine
Added to ASH registry: 2026-05-28
Postprocedure bivalirudin infusion for primary percutaneous coronary intervention
Shah et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-28
Prothrombin complex concentrate for vitamin K antagonist reversal in acute bleeding settings: efficacy and safety
Ostermann H et al. · Expert review of hematology
Added to ASH registry: 2026-05-28
Proton Pump Inhibitors and Dabigatran Therapy: Impact on Gastric Bleeding and Dabigatran Plasma Levels
Bolek et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Pulmonary embolism management in the critical care setting.
Handal-Orefice et al. · Seminars in perinatology
Added to ASH registry: 2026-05-28
Removal of dabigatran using sorbent hemadsorption
Angheloiu et al. · International journal of cardiology
Added to ASH registry: 2026-05-28
Repeated mechanical thrombectomy for acute ischemic stroke in a dialysis patient: A case report and literature review.
Ding et al. · Hemodialysis international. International Symposium on Home Hemodialysis
Added to ASH registry: 2026-05-28
Reversal agents for oral anticoagulant-associated major or life-threatening bleeding.
Moia et al. · Internal and emergency medicine
Added to ASH registry: 2026-05-28
Reversal of direct oral anticoagulants: Guidance from the Anticoagulation Forum.
Cuker et al. · American journal of hematology
Added to ASH registry: 2026-05-28
Rivaroxaban after Thrombolysis in Acute Iliofemoral Venous Thrombosis: A Randomized, Open-labeled, Multicenter Trial
Kang et al. · Scientific reports
Added to ASH registry: 2026-05-28
Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial.
Ordi-Ros J et al. · Annals of internal medicine
Added to ASH registry: 2026-05-28
Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome.
Anonymous · Annals of internal medicine
Added to ASH registry: 2026-05-28
Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation.
Iba et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Should we continue to test soluble thrombomodulin, or other systemic anticoagulants, as a life-saving therapy for sepsis-induced coagulopathy?
Laterre et al. · Anaesthesia, critical care & pain medicine
Added to ASH registry: 2026-05-28
Stroke Prevention in Atrial Fibrillation: The Role of Oral Anticoagulation.
Mtwesi et al. · The Medical clinics of North America
Added to ASH registry: 2026-05-28
Sustained safe and effective anticoagulation using Edoxaban via percutaneous endoscopic gastrostomy
Galli et al. · ESC heart failure
Added to ASH registry: 2026-05-28
Thromboelastography-Guided Resuscitation of the Trauma Patient.
Subramanian et al. · JAMA surgery
Added to ASH registry: 2026-05-28
Tissue factor pathway inhibitor in atherosclerosis.
Yuan et al. · Clinica chimica acta; international journal of clinical chemistry
Added to ASH registry: 2026-05-28
Trauma-induced coagulopathy: The past, present, and future.
Kornblith et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Treatment of apixaban- and rivaroxaban-associated major bleeding using 4-factor prothrombin complex concentrate
Sheikh-Taha M · Internal and emergency medicine
Added to ASH registry: 2026-05-28
Treatment of cancer-associated venous thromboembolism in the age of direct oral anticoagulants.
Ay C et al. · Annals of oncology : official journal of the European Society for Medical Oncology
Added to ASH registry: 2026-05-28
Treatment of Pediatric Venous Thromboembolism.
Meier KA et al. · Journal of hospital medicine
Added to ASH registry: 2026-05-28
Use of dabigatran with antiretrovirals
Perram et al. · HIV medicine
Added to ASH registry: 2026-05-28
Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Clinical Practice Guideline Update.
Key et al. · Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Added to ASH registry: 2026-05-28
A novel protease-activated receptor 1 inhibitor from the leech Whitmania pigra
Ren SH et al. · Chinese journal of natural medicines
Added to ASH registry: 2026-05-27
A systematic review and meta-analysis of bivalirudin application in peripheral endovascular procedures
Hu Y et al. · Journal of vascular surgery
Added to ASH registry: 2026-05-27
An assay to measure levels of factor Xa inhibitors in blood and plasma
Kim PY et al. · Journal of Thrombosis and Haemostasis
Added to ASH registry: 2026-05-27
Assessment of residual thrombus burden in patients with ST-segment elevation myocardial infarction undergoing bivalirudin versus unfractionated heparin infusion: The MATRIX (minimizing adverse hemorrhagic events by transradial access site and angioX) OCT study
Garcia-Garcia HM et al. · Catheter Cardiovasc Interv
Added to ASH registry: 2026-05-27
Bivalirudin for pediatric procedural anticoagulation: a narrative review
Zaleski KL et al. · Anesthesia and analgesia
Added to ASH registry: 2026-05-27
Bivalirudin for Pediatric Procedural Anticoagulation: A Narrative Review
Zaleski KL et al. · Anesthesia and analgesia
Added to ASH registry: 2026-05-27
Clinical outcomes after TAVR with heparin or bivalirudin as periprocedural anticoagulation in patients with and without peripheral arterial disease: results from the BRAVO-3 randomized trial
Zilberszac R et al. · Catheterization and cardiovascular interventions
Added to ASH registry: 2026-05-27
Construction of engineered Streptococcus zooepidemicus for the production of hyaluronic acid ligosaccharide
Wei C et al. · Sheng Wu Gong Cheng Xue Bao (Chinese Journal of Biotechnology)
Added to ASH registry: 2026-05-27
De Novo Assessment and Review of Pan-American Pit Viper Anticoagulant and Procoagulant Venom Activities via Kinetomic Analyses
Nielsen VG et al. · Toxins
Added to ASH registry: 2026-05-27
Genetic variation, pseudocryptic diversity, and phylogeny of Erpobdella (Annelida: Hirudinida: Erpobdelliformes), with emphasis on Canadian species
Anderson K et al. · Mol Phylogenet Evol
Added to ASH registry: 2026-05-27
Heparin-induced Thrombocytopenia in Pediatrics Following Cardiopulmonary Bypass
Yuan SM · Journal of the College of Physicians and Surgeons--Pakistan
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia treated with fondaparinux: single center experience
Dulicek P et al. · International angiology
Added to ASH registry: 2026-05-27
High-Quality Studies in Complementary and Alternative Medicine are Necessary
Hubner R et al. · Deutsches Arzteblatt international
Added to ASH registry: 2026-05-27
Impact of sex on comparative outcomes of bivalirudin versus unfractionated heparin in patients with acute coronary syndromes undergoing invasive management: a pre-specified analysis of the MATRIX trial
Gargiulo G et al. · EuroIntervention
Added to ASH registry: 2026-05-27
Individual Patient Data Pooled Analysis of Randomized Trials of Bivalirudin versus Heparin in Acute Myocardial Infarction: Rationale and Methodology
Bikdeli B et al. · Thromb Haemost
Added to ASH registry: 2026-05-27
Leeches attenuate blood hyperviscosity and related metabolic disorders in rats differently than aspirin
Wang X et al. · Journal of ethnopharmacology
Added to ASH registry: 2026-05-27
Linear Peptides Containing d-Leucine with Neuroprotective Activities from the LeechWhitman
Zhang ZY et al. · Journal of natural products
Added to ASH registry: 2026-05-27
Management of Upper Airway Leech Infestations
Harun K et al. · Ear nose & throat journal
Added to ASH registry: 2026-05-27
Na/K-ATPase gene duplications in clitellate annelids are associated with freshwater colonization
Horn KM et al. · Journal of evolutionary biology
Added to ASH registry: 2026-05-27
Novel Strategy of Gene Delivery System Based on Dendrimer Loaded Recombinant Hirudine Plasmid for Thrombus Targeting Therapy
Chen J et al. · Molecular pharmaceutics
Added to ASH registry: 2026-05-27
Novel Strategy of Gene Delivery System Based on Dendrimer Loaded Recombinant Hirudine Plasmid for Thrombus Targeting Therapy
Chen J et al. · Molecular Pharmaceutics
Added to ASH registry: 2026-05-27
Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14
Skjeflo EW et al. · Molecular immunology
Added to ASH registry: 2026-05-27
Pharmacokinetic and pharmacodynamic modeling and simulation analysis of CTB-001, a recently developed generic of bivalirudin
Han S et al. · Pharmaceutical research
Added to ASH registry: 2026-05-27
Phylogenomic Analysis of a Putative Missing Link Sparks Reinterpretation of Leech Evolution
Phillips AJ et al. · Genome biology and evolution
Added to ASH registry: 2026-05-27
Post-Procedural Bivalirudin Infusion atFull or Low Regimen in Patients WithAcute Coronary Syndrome
Gargiulo G et al. · J Am Coll Cardiol
Added to ASH registry: 2026-05-27
Radial versus femoral access in patients with acute coronary syndrome undergoing invasive management: A prespecified subgroup analysis from VALIDATE-SWEDEHEART
Völz S et al. · Eur Heart J Acute Cardiovasc Care
Added to ASH registry: 2026-05-27
Reproductive differences among species, and between individuals and cohorts, in the leech genus Helobdella
Iyer RG et al. · PloS one
Added to ASH registry: 2026-05-27
Responsible, safe, and effective use of antithrombotics and anticoagulants in patients undergoing interventional techniques
Kaye AD et al. · Pain physician
Added to ASH registry: 2026-05-27
Revacept, a Novel Inhibitor of Platelet Adhesion, in Patients Undergoing Elective PCI-Design and Rationale of the Randomized ISAR-PLASTER Trial
Schpke S et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Role of bivalirudin for anticoagulation in adult perioperative cardiothoracic practice
Erdoes G et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
Safety, pharmacokinetics and pharmacodynamics of TNHH, a novel targeted neutrophil-inhibitory hirulog hybrid glycoprotein, in healthy volunteers
Gou ZP et al. · CNS drugs
Added to ASH registry: 2026-05-27
Spatio-temporal variation and the use of host body surface by ectoparasites of the chelonians Phrynops geoffroanus and Mesoclemmys tuberculata
Santana DO et al. · Parasitology research
Added to ASH registry: 2026-05-27
Spatiotemporal Expression of Anticoagulation Factorin Freshwater Leeches
Kwak HJ et al. · Int J Mol Sci
Added to ASH registry: 2026-05-27
The beneficial roles of metformin on the brain with cerebral ischaemia/reperfusion injury
Leech T et al. · Pharmacological research
Added to ASH registry: 2026-05-27
The Direct Thrombin Inhibitors Dabigatran and Lepirudin Inhibit GPIbalpha-Mediated Platelet Aggregation
Trabold K et al. · Thrombosis and Haemostasis
Added to ASH registry: 2026-05-27
The MATRIX trial
Meyer TM et al. · Lancet
Added to ASH registry: 2026-05-27
The MATRIX trial
Shah R et al. · Lancet
Added to ASH registry: 2026-05-27
Titration of Bivalirudin Infusion in the Pediatric Cardiac Catheterization Laboratory: A Case Report
Streiff A et al. · A&A practice
Added to ASH registry: 2026-05-27
Transcriptomic Analysis of the Influence of Methanol Assimilation on the Gene Expression in the RecombinantProducing Hirudin Variant 3
Li T et al. · Genes
Added to ASH registry: 2026-05-27
Vampire Venom: Vasodilatory Mechanisms of Vampire Bat Blood Feeding
Kakumanu R et al. · Toxins
Added to ASH registry: 2026-05-27
A Comprehensive Review of Medicinal Leeches in Plastic and Reconstructive Surgery
Hackenberger PN, Janis JE · Plastic and reconstructive surgery. Global open
Added to ASH registry: 2026-05-26
A novel protease-activated receptor 1 inhibitor from the leech Whitmania pigra
Ren SH, Liu ZJ, Cao Y et al. · Chinese journal of natural medicines
Added to ASH registry: 2026-05-26
Aqueous Extract of Whitmania Pigra Whitman Alleviates Thrombus Burden Via Sirtuin 1/NF-κB Pathway
Yao XL et al. · The Journal of surgical research
Added to ASH registry: 2026-05-26
Hirudins of the Asian medicinal leech, Hirudinaria manillensis: same same, but different
Lukas P et al. · Parasitology research
Added to ASH registry: 2026-03-18
HIRUDOTHERAPY IN PRESBYACUZIS PRAECOX IN CLEAN-UP WORKERS AFTER THE CHORNOBYL ACCIDENT DURING THE POST-CATASTROPHE YEARS
Zabolotnyi D, Mishchanchuk N · Problemy radiatsiinoi medytsyny ta radiobiolohii
Added to ASH registry: 2026-03-18
The effects of a hirudin/liposome complex on a diabetic nephropathy rat model
Wang H et al. · BMC complementary and alternative medicine
Added to ASH registry: 2026-03-18
Apixaban for the treatment of cancer-associated venous thromboembolism and left atrial appendage thrombus refractory to optimal anticoagulation with warfarin: a case report
Koga et al. · European heart journal. Case reports
Added to ASH registry: 2026-05-29
[Antithrombotic therapy in patients with atrial fibrillation and acute coronary syndrome].
Tubaro et al. · Giornale italiano di cardiologia (2006)
Added to ASH registry: 2026-05-28
[Venous thromboembolism and urological cancer: Epidemiology and therapeutically management].
Felber et al. · Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie
Added to ASH registry: 2026-05-28
[Von Willebrand disease].
Calmette L et al. · La Revue de medecine interne
Added to ASH registry: 2026-05-28
A Randomized Trial of the Optimum Duration of Acoustic Pulse Thrombolysis Procedure in Acute Intermediate-Risk Pulmonary Embolism: The OPTALYSE PE Trial.
Tapson VF et al. · JACC. Cardiovascular interventions
Added to ASH registry: 2026-05-28
American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy.
Bates et al. · Blood advances
Added to ASH registry: 2026-05-28
An update on the use of anticoagulant therapy in ST-segment elevation myocardial infarction
van Gameren M et al. · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-28
Andexanet alfa effectively reverses edoxaban anticoagulation effects and associated bleeding in a rabbit acute hemorrhage model
Lu et al. · PloS one
Added to ASH registry: 2026-05-28
Anti-Xa activity in oral factor Xa inhibitor-treated patients with atrial fibrillation and a higher risk of bleeding: a pilot study
Samoš M et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Anticoagulation during ECMO in neonatal and paediatric patients.
Barton et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Anticoagulation for the Treatment of Cancer-Associated Thrombosis: A Systematic Review and Network Meta-Analysis of Randomized Trials.
Sobieraj et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Anticoagulation in atrial fibrillation with heart failure
Zhao et al. · Heart failure reviews
Added to ASH registry: 2026-05-28
Anticoagulation in the management of neonatal cerebral sinovenous thrombosis: a systematic review and meta-analysis.
Rossor et al. · Developmental medicine and child neurology
Added to ASH registry: 2026-05-28
Antiplatelet and anticoagulant activities of two phospholipase A2s purified from Cerastes cerastes venom: Structure-function relationship.
Fatah C et al. · Journal of biochemical and molecular toxicology
Added to ASH registry: 2026-05-28
Apixaban for Treating Venous Thromboembolism in Real-World Clinical Practice
Monreal · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Argatroban dosing in obesity
Elagizi et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Atrial Cardiopathy and Stroke Prevention.
Elkind · Current cardiology reports
Added to ASH registry: 2026-05-28
Betrixaban: A Novel Factor Xa Inhibitor for the Prevention of Venous Thromboembolism in Acutely Ill Medical Patients
Lee et al. · Cardiology in review
Added to ASH registry: 2026-05-28
Bivalirudin Anticoagulation Dosing Protocol for Extracorporeal Membrane Oxygenation: A Retrospective Review.
Netley et al. · The journal of extra-corporeal technology
Added to ASH registry: 2026-05-28
Bivalirudin versus heparin monotherapy in non-ST-segment elevation myocardial infarction.
Erlinge D et al. · European heart journal. Acute cardiovascular care
Added to ASH registry: 2026-05-28
Bivalirudin versus heparin with primary percutaneous coronary intervention
Venetsanos D et al. · American heart journal
Added to ASH registry: 2026-05-28
Catheter-directed Thrombolysis for Intermediate-Risk Pulmonary Embolism.
Furfaro et al. · Annals of the American Thoracic Society
Added to ASH registry: 2026-05-28
Cerebral venous sinus thrombosis.
Capecchi et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Comparison of Anti-Xa Activity in Patients Receiving Apixaban or Rivaroxaban
Bookstaver et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Comparison of argatroban and fondaparinux for the management of patients with isolated heparin-induced thrombocytopenia
Al-Eidan et al. · Annals of hematology
Added to ASH registry: 2026-05-28
Conservative management of neonatal cerebral sinovenous thrombosis with coexisting thrombophilia.
Khatri et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Dabigatran affects thrombin-dependent platelet aggregation after a week-long therapy
Sokol et al. · Scandinavian cardiovascular journal : SCJ
Added to ASH registry: 2026-05-28
Dabigatran inhibits intravitreal thrombin activity
Bastiaans et al. · Acta ophthalmologica
Added to ASH registry: 2026-05-28
Diagnosis and Management of the Antiphospholipid Syndrome.
Garcia et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Disseminated Intravascular Coagulation: An Update on Pathogenesis, Diagnosis, and Therapeutic Strategies.
Papageorgiou et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism
Raskob et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Effectiveness and Safety of Rivaroxaban in Patients With Cancer-Associated Venous Thrombosis
Kohn et al. · Journal of the National Comprehensive Cancer Network : JNCCN
Added to ASH registry: 2026-05-28
Emerging Role of Direct Oral Anticoagulants in the Management of Heparin-Induced Thrombocytopenia
Tran PN et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Emicizumab for hemophilia A with factor VIII inhibitors.
Young G et al. · Expert review of hematology
Added to ASH registry: 2026-05-28
Emicizumab Prophylaxis in Patients Who Have Hemophilia A without Inhibitors.
Mahlangu J et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Exploration of Bivalirudin Use during Percutaneous Coronary Intervention for High Bleeding Risk Patients with Chronic Total Occlusion
Li C et al. · International heart journal
Added to ASH registry: 2026-05-28
Factor XIa Inhibitors as New Anticoagulants
Quan et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Heparin-Induced Thrombocytopenia in Infants after Heart Surgery.
Abdillah et al. · The Thoracic and cardiovascular surgeon
Added to ASH registry: 2026-05-28
How I manage patients with anticoagulation-associated bleeding or urgent surgery.
Sauter et al. · Swiss medical weekly
Added to ASH registry: 2026-05-28
Idarucizumab for Reversing Dabigatran-Induced Anticoagulation: A Systematic Review
Thibault et al. · American journal of therapeutics
Added to ASH registry: 2026-05-28
Idarucizumab: What Should We Know?
Cortese et al. · Current drug targets
Added to ASH registry: 2026-05-28
Incomplete dabigatran reversal with idarucizumab
Steele et al. · Clinical toxicology (Philadelphia, Pa.)
Added to ASH registry: 2026-05-28
Interventional Spine and Pain Procedures in Patients on Antiplatelet and Anticoagulant Medications (Second Edition): Guidelines From the American Society of Regional Anesthesia and Pain Medicine, the European Society of Regional Anaesthesia and Pain Therapy, the American Academy of Pain Medicine, the International Neuromodulation Society, the North American Neuromodulation Society, and the World Institute of Pain
Narouze S et al. · Regional anesthesia and pain medicine
Added to ASH registry: 2026-05-28
Intravenous Thrombolysis in Patients with Acute Ischemic Stroke after a Reversal of Dabigatran Anticoagulation with Idarucizumab: A Real-World Clinical Experience.
Šaňák et al. · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Added to ASH registry: 2026-05-28
Management of antiphospholipid syndrome.
Uthman et al. · Annals of the rheumatic diseases
Added to ASH registry: 2026-05-28
Management of Factor Xa inhibitor-associated life-threatening major hemorrhage: A retrospective multi-center analysis
Milling TJ Jr et al. · The American journal of emergency medicine
Added to ASH registry: 2026-05-28
Mechanical Thrombectomy in Patients with Acute Ischemic Stroke on Anticoagulation Therapy.
Černík et al. · Cardiovascular and interventional radiology
Added to ASH registry: 2026-05-28
Molecular cloning and functional characterization of a short peptidoglycan recognition protein from triangle-shell pearl mussel (Hyriopsis cumingii).
Huang Y et al. · Fish & shellfish immunology
Added to ASH registry: 2026-05-28
Novel heparin mimetics reveal cooperativity between exosite 2 and sodium-binding site of thrombin.
Abdel Aziz et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Oral anticoagulation cost in primary antiphospholipid syndrome: comparison between warfarin and hypothetical rivaroxaban.
Ciampa A et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Oral Anticoagulation.
Altiok et al. · Deutsches Arzteblatt international
Added to ASH registry: 2026-05-28
Patients treated with bivalirudin are still at higher risk of stent thrombosis: a comprehensive meta-analysis of randomised clinical trials of bivalirudin and heparin for percutaneous coronary interventions
Grajek et al. · Kardiologia polska
Added to ASH registry: 2026-05-28
Percutaneous left atrial appendage occlusion in the prevention of stroke in atrial fibrillation: a systematic review.
Baman JR et al. · Heart failure reviews
Added to ASH registry: 2026-05-28
Plasma contact factors as therapeutic targets.
Tillman et al. · Blood reviews
Added to ASH registry: 2026-05-28
Platelet function testing: dead or alive.
Helten et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay.
Warkentin et al. · Chest
Added to ASH registry: 2026-05-28
Platelet-targeted dual pathway antithrombotic inhibits thrombosis with preserved hemostasis.
Hanjaya-Putra et al. · JCI insight
Added to ASH registry: 2026-05-28
Probing light chain mutation effects on thrombin via molecular dynamics simulations and machine learning.
Xiao et al. · Journal of biomolecular structure & dynamics
Added to ASH registry: 2026-05-28
Reversal agents for non-vitamin K antagonist oral anticoagulants.
Levy et al. · Nature reviews. Cardiology
Added to ASH registry: 2026-05-28
Reversal Strategies for Intracranial Hemorrhage Related to Direct Oral Anticoagulant Medications.
Dabi et al. · Critical care research and practice
Added to ASH registry: 2026-05-28
rFVIIIFC for hemophilia A prophylaxis.
Mahlangu J · Expert review of hematology
Added to ASH registry: 2026-05-28
Rivaroxaban and apixaban induce clotting factor Xa fibrinolytic activity
Carter RLR et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Rivaroxaban versus nadroparin for preventing deep venous thrombosis after total hip arthroplasty following femoral neck fractures: A retrospective comparative study
Zhang et al. · The Journal of international medical research
Added to ASH registry: 2026-05-28
Rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome.
Pengo V et al. · Blood
Added to ASH registry: 2026-05-28
Sex-related response to bivalirudin and unfractionated heparin in patients with acute myocardial infarction undergoing percutaneous coronary intervention: A subgroup analysis of the VALIDATE-SWEDEHEART trial.
Venetsanos et al. · European heart journal. Acute cardiovascular care
Added to ASH registry: 2026-05-28
Splanchnic Vein Thrombosis in the Myeloproliferative Neoplasms.
Akpan et al. · Current hematologic malignancy reports
Added to ASH registry: 2026-05-28
State of the art in factor XIII laboratory assessment.
Durda et al. · Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
Added to ASH registry: 2026-05-28
State of the Art Management of Mechanical Heart Valves During Pregnancy.
Aggarwal et al. · Current treatment options in cardiovascular medicine
Added to ASH registry: 2026-05-28
Structural basis for the selective inhibition of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) by a selenium-containing inhibitor with chloro-aminopyridine as a basic group
Itoh et al. · Bioorganic & medicinal chemistry letters
Added to ASH registry: 2026-05-28
Submassive Pulmonary Embolism.
Rali et al. · American journal of respiratory and critical care medicine
Added to ASH registry: 2026-05-28
Symptomatic event reduction with extended-duration betrixaban in acute medically ill hospitalized patients
Gibson et al. · American heart journal
Added to ASH registry: 2026-05-28
Systematic Review and Meta-Analysis of Real-World Studies Evaluating Rivaroxaban for Cancer-Associated Venous Thrombosis
Martinez et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Systemic Thrombolysis for Pulmonary Embolism: Evidence, Patient Selection, and Protocols for Management.
Virk et al. · Interventional cardiology clinics
Added to ASH registry: 2026-05-28
Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke.
Campbell BCV et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
The clinical impact of edoxaban for the patients with postoperative anemia after total hip arthroplasty
Izushi et al. · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Added to ASH registry: 2026-05-28
Thrombin-like enzymes from snake venom: Structural characterization and mechanism of action
Ullah et al. · International journal of biological macromolecules
Added to ASH registry: 2026-05-28
Treatment algorithm in cancer-associated thrombosis: Canadian expert consensus.
Carrier et al. · Current oncology (Toronto, Ont.)
Added to ASH registry: 2026-05-28
Uninterrupted anticoagulation with non-vitamin K antagonist oral anticoagulants in atrial fibrillation catheter ablation: Lessons learned from randomized trials.
Cardoso R et al. · Clinical cardiology
Added to ASH registry: 2026-05-28
Using metabarcoding to compare the suitability of two blood-feeding leech species for sampling mammalian diversity in North Borneo
Drinkwater R et al. · Molecular ecology resources
Added to ASH registry: 2026-05-28
Venous thromboembolism controversies.
Salazar Adum et al. · Disease-a-month : DM
Added to ASH registry: 2026-05-28
Venous thromboembolism incidence in hematologic malignancies.
Kekre et al. · Blood reviews
Added to ASH registry: 2026-05-28
A functional and thromboelastometric-based micromethod for assessing crotoxin anticoagulant activity and antiserum relative potency against Crotalus durissus terrificus venom
Prezoto BC et al. · Toxicon
Added to ASH registry: 2026-05-27
A Patient With Remote Heparin-Induced Thrombocytopenia and Antiphospholipid Syndrome Requiring Cardiopulmonary Bypass: Do Current Guidelines Apply?
Ibrahim W et al. · Semin Cardiothorac Vasc Anesth
Added to ASH registry: 2026-05-27
American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia
Cuker A et al. · Blood advances
Added to ASH registry: 2026-05-27
Bivalirudin during percutaneous coronary intervention in acute coronary syndromes
Laine M et al. · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-27
Bivalirudin for left ventricular assist device thrombosis
Weeks P et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-27
Bivalirudin or Heparin in Patients Undergoing Invasive Management of AcuteCoronarySyndromes
Gargiulo G et al. · J Am Coll Cardiol
Added to ASH registry: 2026-05-27
Cadmium selenide quantum dot-zinc oxide composite: Synthesis, characterization, dye removal ability with UV irradiation, and antibacterial activity as a safe and high-performance photocatalyst
Mahmoodi NM et al. · Journal of photochemistry and photobiology. B, Biology
Added to ASH registry: 2026-05-27
Clinical effects with inhibition of multiple coagulative pathways in patients admitted for acute coronary syndrome
Cavallari I et al. · Internal and emergency medicine
Added to ASH registry: 2026-05-27
Combined systems pharmacology and fecal metabonomics to study the biomarkers and therapeutic mechanism of type 2 diabetic nephropathy treated with leech
Chen R et al. · RSC advances
Added to ASH registry: 2026-05-27
Compact and Economical Microsurgical Training Made Possible with Virtual Reality
Huang TC et al. · Plastic and reconstructive surgery
Added to ASH registry: 2026-05-27
Comparison of two pediatric cases requiring the use of bivalirudin during cardiopulmonary bypass
Bryant ME et al. · Perfusion
Added to ASH registry: 2026-05-27
Comparison table: some parenteral anticoagulants for VTE
Unknown · The Medical letter on drugs and therapeutics
Added to ASH registry: 2026-05-27
Complications and Pitfalls after Finger Replantation in Young Children
Lafosse T et al. · Journal of hand and microsurgery
Added to ASH registry: 2026-05-27
Drugs for treatment and prevention of venous thromboembolism
Unknown · The Medical letter on drugs and therapeutics
Added to ASH registry: 2026-05-27
Effect of Astragali Radix on growth, immunity and related gene expression of Whitmania pigra
Wu B et al. · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Added to ASH registry: 2026-05-27
Effects of combined natural hirudin and hyperbaric oxygen therapy on survival of transplanted random-pattern skin flap in rats
Cai J et al. · Zhongguo xiu fu chong jian wai ke za zhi
Added to ASH registry: 2026-05-27
Efficacy and safety of bivalirudin for percutaneous coronary intervention in acute coronary syndromes: a meta-analysis of randomized-controlled trials
Nhrenberg TG et al. · Clinical research in cardiology : official journal of the German Cardiac Society
Added to ASH registry: 2026-05-27
Evaluating prodrug characteristics of a novel anticoagulant fusion protein neorudin, a prodrug targeting release of hirudin variant 2-Lys47 at the thrombosis site
Dong X et al. · European journal of pharmaceutical sciences
Added to ASH registry: 2026-05-27
Experience with pharmacologic leeching with bivalirudin for adjunct treatment of venous congestion of head and neck reconstructive flaps
Harun A et al. · Microsurgery
Added to ASH registry: 2026-05-27
Heparin-Induced Thrombocytopenia during Obstetric Hospital Admissions
Sagaram D et al. · American journal of perinatology
Added to ASH registry: 2026-05-27
In the transition from fibrinolysis to primary PCI, the HERO trials help refine STEMI ECG interpretation and Q wave analysis potentially alters future management
Wong CK et al. · European heart journal. Acute cardiovascular care
Added to ASH registry: 2026-05-27
Microfluidic Modeling of Thrombolysis
Loyau S et al. · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-27
Monitoring of argatroban and lepirudin anticoagulation in critically ill patients by conventional laboratory parameters and rotational thromboelastometry
Beiderlinden M et al. · BMC anesthesiology
Added to ASH registry: 2026-05-27
Monitoring of argatroban and lepirudin anticoagulation in critically ill patients by conventional laboratory parameters and rotational thromboelastometry — ALicia substudy
Beiderlinden M et al. · BMC Anesthesiology
Added to ASH registry: 2026-05-27
Noncoded amino acids in protein engineering: Structure-activity relationship studies of hirudin-thrombin interaction
De Filippis V et al. · Biotechnology and applied biochemistry
Added to ASH registry: 2026-05-27
Overcoming Heparin-Associated RT-qPCR Inhibition and Normalization Issues for microRNA Quantification in Patients with Acute Myocardial Infarction
Coelho-Lima J et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Phylogenetic and morphological resolution of the Helobdella stagnalis species-complex (Annelida: Clitellata: Hirudinea)
Saglam N et al. · Zootaxa
Added to ASH registry: 2026-05-27
Radial versus femoral access and bivalirudin versus unfractionated heparin in invasively managed patients with acute coronary syndrome (MATRIX): final 1-year results of a multicentre, randomised controlled trial
Valgimigli M et al. · Lancet
Added to ASH registry: 2026-05-27
Randomized Controlled Trial of Heparin Versus Bivalirudin Anticoagulation in Acyanotic Children Undergoing Open Heart Surgery
Hasija S et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
Role of isopeptidolysis in the process of thrombolysis
Baskova IP et al. · Thrombosis research
Added to ASH registry: 2026-05-27
Safety and efficacy of switching from unfractionated heparin to bivalirudin during primary percutaneous coronary intervention
Shah R et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-27
Temporal and spatial expression of the Fox gene family in the Leech Helobdella austinensis
Kwak HJ et al. · Journal of experimental zoology Part B
Added to ASH registry: 2026-05-27
Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization
Chang HW et al. · Microbiome
Added to ASH registry: 2026-05-26
Hirudin variants production by genetic engineered microbial factory
Zhang J, Lan N · Biotechnology & genetic engineering reviews
Added to ASH registry: 2026-03-18
Transcriptomic analysis of the salivary gland of medicinal leech Hirudo nipponia
Lu Z et al. · PloS one
Added to ASH registry: 2026-03-18
9-Phenanthrol modulates postinhibitory rebound and afterhyperpolarizing potentials in an excitatory motor neuron of the medicinal leech
Angstadt JD et al. · Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology
Added to ASH registry: 2026-05-28
An updated meta-analysis of novel oral anticoagulants versus vitamin K antagonists for uninterrupted anticoagulation in atrial fibrillation catheter ablation.
Cardoso R et al. · Heart rhythm
Added to ASH registry: 2026-05-28
Andexanet alfa for the reversal of anticoagulant activity in patients treated with direct and indirect factor Xa inhibitors
Nafee et al. · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-28
Andexanet alfa: a recombinant mimetic of human factor Xa for the reversal of anticoagulant therapies.
Escolar G et al. · Drugs of today (Barcelona, Spain : 1998)
Added to ASH registry: 2026-05-28
Anticoagulant Therapy in Sepsis. The Importance of Timing.
Scarlatescu et al. · Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)
Added to ASH registry: 2026-05-28
Anticoagulation Therapy in Children.
Radulescu · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Antithrombotic therapy for acute coronary syndrome: Past, present and future.
Sibbing et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Autoimmune heparin-induced thrombocytopenia.
Greinacher et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Bivalirudin in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: uncertainties almost clarified
Huber K et al. · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Added to ASH registry: 2026-05-28
Bivalirudin in percutaneous coronary intervention for chronic total occlusion: A single-center pilot study.
Li C et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-28
Bivalirudin versus heparin in women undergoing percutaneous coronary intervention: A systematic review and meta-analysis of randomized clinical trials
Saad M et al. · Cardiovascular revascularization medicine : including molecular interventions
Added to ASH registry: 2026-05-28
Bivalirudin versus Heparin plus Glycoprotein IIb/IIIa Inhibitors in Women Undergoing Percutaneous Coronary Intervention: A Meta-Analysis of Randomized Controlled Trials
Xu H et al. · PloS one
Added to ASH registry: 2026-05-28
Cardioembolic Stroke.
Kamel et al. · Circulation research
Added to ASH registry: 2026-05-28
Catastrophic antiphospholipid syndrome on switching from warfarin to rivaroxaban.
Crowley MP et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Catheter-Directed Thrombolysis Versus Standard Anticoagulation for Acute Lower Extremity Deep Vein Thrombosis: A Meta-Analysis of Clinical Trials.
Lu Y et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Cerebral venous sinus thrombosis.
Sriram et al. · British journal of hospital medicine (London, England : 2005)
Added to ASH registry: 2026-05-28
Coagulation Testing in the Core Laboratory.
Winter WE et al. · Laboratory medicine
Added to ASH registry: 2026-05-28
Dabigatran - Metabolism, Pharmacologic Properties and Drug Interactions
Antonijevic et al. · Current drug metabolism
Added to ASH registry: 2026-05-28
Dabigatran enhances platelet reactivity and platelet thrombin receptor expression in patients with atrial fibrillation.
Achilles et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Dabigatran Etexilate: A Review in Nonvalvular Atrial Fibrillation.
Blair et al. · Drugs
Added to ASH registry: 2026-05-28
Dabigatran etexilate: appropriate use in patients with chronic kidney disease and in the elderly patients
Molteni et al. · Internal and emergency medicine
Added to ASH registry: 2026-05-28
Dabigatran in nonvalvular atrial fibrillation: from clinical trials to real-life experience.
Mumoli et al. · Journal of cardiovascular medicine (Hagerstown, Md.)
Added to ASH registry: 2026-05-28
Dabigatran Reversal with Idarucizumab
Yip et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Dabigatran Reversal with Idarucizumab
Pollack et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Dabigatran Reversal with Idarucizumab
Sorigue · The New England journal of medicine
Added to ASH registry: 2026-05-28
Dabigatran reversal with idarucizumab in a patient undergoing heart transplantation: first European report.
Tralhão et al. · Thrombosis journal
Added to ASH registry: 2026-05-28
Development of bioanalytical assays for variegin, a peptide-based bivalent direct thrombin inhibitor
Shih et al. · Bioanalysis
Added to ASH registry: 2026-05-28
Diagnosis and Treatment of von Willebrand Disease and Rare Bleeding Disorders.
Castaman G et al. · Journal of clinical medicine
Added to ASH registry: 2026-05-28
Diagnostic Accuracy of a Novel Chromogenic Direct Thrombin Inhibitor Assay: Clinical Experiences for Dabigatran Monitoring
Poli et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Direct acting oral anticoagulants for the treatment of suspected heparin-induced thrombocytopenia
Davis KA et al. · European journal of haematology
Added to ASH registry: 2026-05-28
Direct oral anticoagulant reversal: how, when and issues faced.
Dzeshka et al. · Expert review of hematology
Added to ASH registry: 2026-05-28
Direct oral anticoagulants: An update.
Franco Moreno et al. · Medicina clinica
Added to ASH registry: 2026-05-28
Direct thrombin inhibition with dabigatran attenuates pressure overload-induced cardiac fibrosis and dysfunction in mice
Dong et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212)
Pinto et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Discovery of Chromen-7-yl Furan-2-Carboxylate as a Potent and Selective Factor XIa Inhibitor
Obaidullah et al. · Cardiovascular & hematological agents in medicinal chemistry
Added to ASH registry: 2026-05-28
Edoxaban: A direct oral anticoagulant.
Poulakos et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Edoxaban: How Does the Newest Agent Fit into the DOAC Landscape?
Gibson et al. · The American journal of medicine
Added to ASH registry: 2026-05-28
Efficacy and safety of bivalirudin versus heparin in patients with diabetes mellitus undergoing percutaneous coronary intervention: A meta-analysis of randomized controlled trials
Zhang J et al. · Medicine
Added to ASH registry: 2026-05-28
Evaluation of novel factor Xa inhibitors from Oxya chinensis sinuosa with anti-platelet aggregation activity
Lee et al. · Scientific reports
Added to ASH registry: 2026-05-28
Fibrin Formation, Structure and Properties.
Weisel et al. · Sub-cellular biochemistry
Added to ASH registry: 2026-05-28
Fibrinogen Mahdia: A congenitally abnormal fibrinogen characterized by defective fibrin polymerization.
Amri et al. · Haemophilia : the official journal of the World Federation of Hemophilia
Added to ASH registry: 2026-05-28
Functional analyses yield detailed insight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from
Pirone L et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Gender-based outcomes of bivalirudin versus heparin in patients undergoing percutaneous coronary interventions: Meta-analysis of randomized controlled trials
Mina et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-28
Generation and characterization of aptamers targeting factor XIa
Woodruff et al. · Thrombosis research
Added to ASH registry: 2026-05-28
H,N andC resonance assignments of Ixolaris, a tissue factor pathway inhibitor from the tick salivary gland.
De Paula VS et al. · Biomolecular NMR assignments
Added to ASH registry: 2026-05-28
How I treat disseminated intravascular coagulation.
Levi et al. · Blood
Added to ASH registry: 2026-05-28
How I treat pediatric venous thromboembolism.
Young G · Blood
Added to ASH registry: 2026-05-28
Idarucizumab for Dabigatran Reversal - Full Cohort Analysis
Pollack et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Idarucizumab for the Reversal of Dabigatran.
Gottlieb et al. · Annals of emergency medicine
Added to ASH registry: 2026-05-28
Identifying novel factor XIIa inhibitors with PCA-GA-SVM developed vHTS models
Chen et al. · European journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Impact of anticoagulation strategy with bivalirudin or heparin on nonaccess site bleeding in percutaneous coronary interventions: A meta-analysis of randomized trials
Verdoia et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-28
Impact of Thrombolytic Therapy on the Long-Term Outcome of Intermediate-Risk Pulmonary Embolism.
Konstantinides SV et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
International Normalized Ratio Is Significantly Elevated With Rivaroxaban and Apixaban Drug Therapies: A Retrospective Study
Ofek F et al. · Clinical therapeutics
Added to ASH registry: 2026-05-28
Joannsin, a novel Kunitz-type FXa inhibitor from the venom of Prospirobolus joannsi.
Luan et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Left Atrial Appendage Occlusion for Stroke Prevention.
Chanda A et al. · Progress in cardiovascular diseases
Added to ASH registry: 2026-05-28
Left Atrial Appendage Occlusion/Exclusion: Procedural Image Guidance with Transesophageal Echocardiography.
Vainrib AF et al. · Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
Added to ASH registry: 2026-05-28
Macrocyclic factor XIa inhibitors
Wang et al. · Bioorganic & medicinal chemistry letters
Added to ASH registry: 2026-05-28
Management of Trauma-Induced Coagulopathy with Thrombelastography.
Gonzalez et al. · Critical care clinics
Added to ASH registry: 2026-05-28
Measurement and reversal of the direct oral anticoagulants.
Samuelson et al. · Blood reviews
Added to ASH registry: 2026-05-28
Measuring Dabigatran Levels: What Tests Are Available and What Still Needs to Be Done?
Chan et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Measuring Direct Oral Anticoagulants
Gosselin RC et al. · Methods in molecular biology (Clifton, N.J.)
Added to ASH registry: 2026-05-28
Mechanical thrombectomy in orally anticoagulated patients with acute ischemic stroke.
Zapata-Wainberg et al. · Journal of neurointerventional surgery
Added to ASH registry: 2026-05-28
Mechanically Oriented 3D Collagen Hydrogel for Directing Neurite Growth.
Antman-Passig M et al. · Tissue engineering. Part A
Added to ASH registry: 2026-05-28
Mobile pump deep vein thrombosis prophylaxis: just say no to drugs
Haynes J et al. · The bone & joint journal
Added to ASH registry: 2026-05-28
Neonatal Venous Thromboembolism.
Haley KM · Frontiers in pediatrics
Added to ASH registry: 2026-05-28
New criteria for sepsis-induced coagulopathy (SIC) following the revised sepsis definition: a retrospective analysis of a nationwide survey.
Iba et al. · BMJ open
Added to ASH registry: 2026-05-28
Novel direct factor Xa inhibitory compounds from Tenebrio molitor with anti-platelet aggregation activity
Lee et al. · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Added to ASH registry: 2026-05-28
Old and new oral anticoagulants: Food, herbal medicines and drug interactions.
Di Minno A et al. · Blood reviews
Added to ASH registry: 2026-05-28
Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis.
López-López et al. · BMJ (Clinical research ed.)
Added to ASH registry: 2026-05-28
Oral anticoagulation in primary care
Altirriba et al. · Revista espanola de sanidad penitenciaria
Added to ASH registry: 2026-05-28
Patients' experience of the monitoring of free flaps after reconstruction for oral cancer
Nazir H et al. · The British journal of oral & maxillofacial surgery
Added to ASH registry: 2026-05-28
Peptide Macrocycle Inhibitor of Coagulation Factor XII with Subnanomolar Affinity and High Target Selectivity
Middendorp et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Platelet Aggregometry Testing: Molecular Mechanisms, Techniques and Clinical Implications.
Koltai et al. · International journal of molecular sciences
Added to ASH registry: 2026-05-28
Platelet Function Analyzed by Light Transmission Aggregometry.
Hvas et al. · Methods in molecular biology (Clifton, N.J.)
Added to ASH registry: 2026-05-28
Portal Vein Thrombosis: Recent Advance.
Qi · Advances in experimental medicine and biology
Added to ASH registry: 2026-05-28
Prevalence and Overtesting of True Heparin-Induced Thrombocytopenia in a 591-Bed Tertiary Care, Teaching Hospital.
Farley et al. · Journal of intensive care medicine
Added to ASH registry: 2026-05-28
Randomized, Multicenter Trial of ARTSS-2 (Argatroban With Recombinant Tissue Plasminogen Activator for Acute Stroke).
Barreto AD et al. · Stroke
Added to ASH registry: 2026-05-28
Real-World Experience with Idarucizumab to Reverse Anticoagulant Effect in Dabigatran-Treated Patients: Report of 11 Cases from Taiwan.
Tsai et al. · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Added to ASH registry: 2026-05-28
Real-world use of idarucizumab for dabigatran reversal in three cases of serious bleeding.
Gendron et al. · Clinical case reports
Added to ASH registry: 2026-05-28
Recombinant and chemo-/bio-orthogonal synthesis of liposomal thrombomodulin and its antithrombotic activity.
Wang et al. · Journal of bioscience and bioengineering
Added to ASH registry: 2026-05-28
Reversal of dabigatran-associated bleeding using idarucizumab: review of the current evidence
Giustozzi et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Reversal of Newer Direct Oral Anticoagulant Drugs (DOACs).
Hussain et al. · Cardiovascular & hematological agents in medicinal chemistry
Added to ASH registry: 2026-05-28
Reversing factor Xa inhibitors - clinical utility of andexanet alfa
Kaatz et al. · Journal of blood medicine
Added to ASH registry: 2026-05-28
Risk-adapted management of pulmonary embolism.
Barco et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Rivaroxaban in the Treatment of PICC-associated Upper Extremity Venous Thrombosis
Fan et al. · Clinical therapeutics
Added to ASH registry: 2026-05-28
Role of agents for reversing the effects of target-specific oral anticoagulants.
Riley et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Single-dose ciraparantag safely and completely reverses anticoagulant effects of edoxaban.
Ansell et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
The Evaluation of Pharmacodynamics and Pharmacokinetics of Anti-thrombin DNA Aptamer RA-36
Zavyalova E et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-28
Treatment of central venous catheter-associated deep venous thrombosis in cancer patients with rivaroxaban
Laube et al. · American journal of hematology
Added to ASH registry: 2026-05-28
Tyrosine sulfation modulates activity of tick-derived thrombin inhibitors
Thompson RE et al. · Nature chemistry
Added to ASH registry: 2026-05-28
Uninterrupted Dabigatran versus Warfarin for Ablation in Atrial Fibrillation.
Calkins H et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Whole Blood Platelet Aggregometry.
Fritsma et al. · Methods in molecular biology (Clifton, N.J.)
Added to ASH registry: 2026-05-28
A Comprehensive Review of Hirudiniasis: From Historic Uses of Leeches to Modern Treatments of Their Bites
Joslin J et al. · Wilderness & environmental medicine
Added to ASH registry: 2026-05-27
A substrate-selective enzyme-catalysis assembly strategy for oligopeptide hydrogel-assisted combinatorial protein delivery
Jiang T et al. · Nano letters
Added to ASH registry: 2026-05-27
Anticoagulation in children: making the most of little patients and little evidence
Young G · Blood cells, molecules & diseases
Added to ASH registry: 2026-05-27
Antithrombotic strategies in the catheterization laboratory for patients with acute coronary syndromes undergoing percutaneous coronary interventions: insights from the EmploYEd antithrombotic therapies in patients with acute coronary Syndromes HOspitalized in iTalian cardiac care units Registry
De Luca L et al. · Journal of cardiovascular medicine (Hagerstown, Md.)
Added to ASH registry: 2026-05-27
Assessment of Fibrin Polymerization During Bivalirudin Anticoagulation for Transcatheter Aortic Valve Replacement
Wipfli C et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
Bivalirudin as an Alternative Anticoagulant for Cardiopulmonary Bypass During Adult Cardiac Surgery-A Change in Practice
Gatt P et al. · J Extra Corpor Technol
Added to ASH registry: 2026-05-27
Bivalirudin versus heparin in patients undergoing percutaneous transcatheter aortic valve interventions: A systematic review and meta-analysis
Villablanca PA et al. · Journal of interventional cardiology
Added to ASH registry: 2026-05-27
Comparisons of argatroban to lepirudin and bivalirudin in the treatment of heparin-induced thrombocytopenia: a systematic review and meta-analysis
Sun Z et al. · International journal of hematology
Added to ASH registry: 2026-05-27
Development, validation, and clinical pharmacokinetic application of UPLC-MS/MS method for hirudin variant in human plasma
Dong X et al. · Journal of chromatography. B
Added to ASH registry: 2026-05-27
Effect of valve design and anticoagulation strategy on 30-day clinical outcomes in transcatheter aortic valve replacement: Results from the BRAVO 3 randomized trial
Linke A et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-27
Effects and related mechanism of bivalirudin on the survival of random skin flap on the back of rat
Cai LY et al. · Zhonghua Shao Shang Za Zhi (Chinese Journal of Burns)
Added to ASH registry: 2026-05-27
Efficacy and safety of bivalirudin in coronary artery disease patients with mild to moderate chronic kidney disease: Meta-analysis
Zeng X et al. · J Cardiol
Added to ASH registry: 2026-05-27
Efficacy and safety of bivalirudin in coronary artery disease patients with mild to moderate chronic kidney disease: Meta-analysis
Zeng X et al. · Journal of Cardiology
Added to ASH registry: 2026-05-27
Expression patterns of duplicated snail genes in the leech Helobdella
Kim JS et al. · Development genes and evolution
Added to ASH registry: 2026-05-27
In-Hospital Outcome Comparing Bivalirudin to Heparin in Real-World Primary Percutaneous Coronary Intervention
Hasun M et al. · Am J Cardiol
Added to ASH registry: 2026-05-27
Laboratory Monitoring of Parenteral Direct Thrombin Inhibitors
Van Cott EM et al. · Seminars in Thrombosis and Hemostasis
Added to ASH registry: 2026-05-27
Management of refractory bleeding post-cardiopulmonary bypass in an acute heparin-induced thrombocytopenia type II renal failure patient who underwent urgent cardiac surgery with bivalirudin (Angiox) anticoagulation
Hassen K et al. · Perfusion
Added to ASH registry: 2026-05-27
Monitoring of Argatroban and Lepirudin: What is the Input of Laboratory Values in Real Life?
Seidel H et al. · Clinical and applied thrombosis/hemostasis
Added to ASH registry: 2026-05-27
Overtreatment of Heparin-Induced Thrombocytopenia in the Surgical ICU
Harada MY et al. · Critical care medicine
Added to ASH registry: 2026-05-27
Periprocedural anticoagulation in transcatheter aortic valve replacement: Heparin vs bivalirudin
Minhas AMK et al. · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences
Added to ASH registry: 2026-05-27
Revisiting antithrombotic therapeutics; sculptin, a novel specific, competitive, reversible, scissile and tight binding inhibitor of thrombin
Iqbal A et al. · Scientific reports
Added to ASH registry: 2026-05-27
Safety and Effectiveness of Bivalirudin in Patients Undergoing Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis
Ahmad Hamdi AH et al. · Frontiers in pharmacology
Added to ASH registry: 2026-05-27
Use of Fondaparinux Off-Label or Approved Anticoagulants for Management of Heparin-Induced Thrombocytopenia
Schindewolf M et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-27
Whitmania Pigra Whitman Extracts Inhibit Lipopolysaccharide Induced Rat Vascular Smooth Muscle Cells Migration and their Adhesion Ability to THP-1 and RAW 264.7 Cells
Li S et al. · Journal of atherosclerosis and thrombosis
Added to ASH registry: 2026-05-27
Effectiveness of topical gel of medical leech (Hirudo medicinalis) saliva extract on patients with knee osteoarthritis: A randomized clinical trial
Shakouri A, Adljouy N, Balkani S et al. · Complementary therapies in clinical practice
Added to ASH registry: 2026-05-26
In-vitro antileishmanial potential of peptide drug hirudin
Khan H et al. · Chemical biology & drug design
Added to ASH registry: 2026-03-18
A direct thrombin inhibitor suppresses protein C activation and factor Va degradation in human plasma: Possible mechanisms of paradoxical enhancement of thrombin generation
Kamisato et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile.
Al-Horani RA et al. · PloS one
Added to ASH registry: 2026-05-28
Allosteric Partial Inhibition of Monomeric Proteases. Sulfated Coumarins Induce Regulation, not just Inhibition, of Thrombin.
Verespy S et al. · Scientific reports
Added to ASH registry: 2026-05-28
Allosterism-based simultaneous, dual anticoagulant and antiplatelet action: allosteric inhibitor targeting the glycoprotein Ibα-binding and heparin-binding site of thrombin.
Mehta AY et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
An Observational Study of the Factor Xa Inhibitors Rivaroxaban and Apixaban as Reported to Eight Poison Centers
Spiller HA et al. · Annals of emergency medicine
Added to ASH registry: 2026-05-28
An updated comprehensive meta-analysis of bivalirudin vs heparin use in primary percutaneous coronary intervention
Shah R et al. · American heart journal
Added to ASH registry: 2026-05-28
Andexanet Alfa for Factor Xa Inhibitor Reversal
Hunt et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Andexanet Alfa for Factor Xa Inhibitor Reversal
Connolly et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Andexanet Alfa for Factor Xa Inhibitor Reversal
Shatzel et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Andexanet alfa for the reversal of Factor Xa inhibitor related anticoagulation.
Ghadimi et al. · Expert review of hematology
Added to ASH registry: 2026-05-28
Anticoagulation and Renal Insufficiency
Koulouri et al. · Therapeutische Umschau. Revue therapeutique
Added to ASH registry: 2026-05-28
Anticoagulation in coronary intervention
Zeymer et al. · European heart journal
Added to ASH registry: 2026-05-28
Apixaban: A Review in Venous Thromboembolism
Greig et al. · Drugs
Added to ASH registry: 2026-05-28
Betrixaban - the next direct factor Xa inhibitor?
Thoenes et al. · Expert review of hematology
Added to ASH registry: 2026-05-28
Bivalirudin in Current Practice: Melius Abundare Quam Deficere?
Valgimigli et al. · JACC. Cardiovascular interventions
Added to ASH registry: 2026-05-28
Bivalirudin versus unfractionated heparin for percutaneous coronary intervention with radial access: A meta-analysis of randomized trials
Mahmoud AN et al. · International journal of cardiology
Added to ASH registry: 2026-05-28
Bivalirudin Versus Unfractionated Heparin in Acute Coronary Syndromes: An Updated Meta-analysis of Randomized Trials
Verdoia et al. · Revista espanola de cardiologia (English ed.)
Added to ASH registry: 2026-05-28
Cardiopulmonary Bypass Without Heparin.
Rehfeldt et al. · Seminars in cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-28
Changing the selectivity profile - from substrate analog inhibitors of thrombin and factor Xa to potent matriptase inhibitors
Maiwald et al. · Journal of enzyme inhibition and medicinal chemistry
Added to ASH registry: 2026-05-28
Ciraparantag safely and completely reverses the anticoagulant effects of low molecular weight heparin.
Ansell et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Dabigatran in clinical practice: Contemporary overview of the evidence
Ageno et al. · International journal of cardiology
Added to ASH registry: 2026-05-28
Dabigatran in real-world atrial fibrillation. Meta-analysis of observational comparison studies with vitamin K antagonists.
Carmo et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Daboxin P, a Major Phospholipase A2 Enzyme from the Indian Daboia russelii russelii Venom Targets Factor X and Factor Xa for Its Anticoagulant Activity.
Sharma et al. · PloS one
Added to ASH registry: 2026-05-28
Design, synthesis and antithrombotic evaluation of novel non-peptide thrombin inhibitors
Chen D et al. · Bioorganic & medicinal chemistry
Added to ASH registry: 2026-05-28
Disseminated intravascular coagulation.
Gando et al. · Nature reviews. Disease primers
Added to ASH registry: 2026-05-28
Edoxaban: A Novel Factor Xa Inhibitor for the Management of Non-valvular Atrial Fibrillation and Venous Thromboembolism
Kubli et al. · Cardiology in review
Added to ASH registry: 2026-05-28
Effect of Post-Primary Percutaneous Coronary Intervention Bivalirudin Infusion on Acute Stent Thrombosis: Meta-Analysis of Randomized Controlled Trials
Shah R et al. · JACC. Cardiovascular interventions
Added to ASH registry: 2026-05-28
Efficacy and safety of bivalirudin versus heparin in patients undergoing percutaneous coronary intervention: A meta-analysis of randomized controlled trials
Zhang S et al. · International journal of cardiology
Added to ASH registry: 2026-05-28
Efficacy of prothrombin complex concentrates for the emergency reversal of dabigatran-induced anticoagulation
Grottke et al. · Critical care (London, England)
Added to ASH registry: 2026-05-28
Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity
Zhou et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Establishing Edoxaban's Role in Anticoagulation
Guirguis et al. · Journal of pharmacy practice
Added to ASH registry: 2026-05-28
EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome.
Andreoli et al. · Annals of the rheumatic diseases
Added to ASH registry: 2026-05-28
Evidence supporting idarucizumab for the reversal of dabigatran.
Pollack · The American journal of emergency medicine
Added to ASH registry: 2026-05-28
Evidence Supporting Idarucizumab for the Reversal of Dabigatran.
Pollack · The American journal of medicine
Added to ASH registry: 2026-05-28
Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients
Cohen et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Factor Xa inhibitors: a novel therapeutic class for the treatment of nonvalvular atrial fibrillation
McCarty et al. · Therapeutic advances in cardiovascular disease
Added to ASH registry: 2026-05-28
Factor XI as a Therapeutic Target
Gailani et al. · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-28
Factor XIa inhibitors: A review of the patent literature
Al-Horani et al. · Expert opinion on therapeutic patents
Added to ASH registry: 2026-05-28
G-Quadruplex Aptamers to Human Thrombin Versus Other Direct Thrombin Inhibitors: The Focus on Mechanism of Action and Drug Efficiency as Anticoagulants.
Zavyalova E et al. · Current medicinal chemistry
Added to ASH registry: 2026-05-28
Goal-directed Hemostatic Resuscitation of Trauma-induced Coagulopathy: A Pragmatic Randomized Clinical Trial Comparing a Viscoelastic Assay to Conventional Coagulation Assays.
Gonzalez et al. · Annals of surgery
Added to ASH registry: 2026-05-28
Heparin Versus Bivalirudin Monotherapy in the Setting of Primary Percutaneous Coronary Intervention for Patients With ST-Segment Elevation Myocardial Infarction
Faulkenberg KD et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Idarucizumab for Dabigatran Reversal Guideline.
Reardon et al. · Critical pathways in cardiology
Added to ASH registry: 2026-05-28
Idarucizumab for Reversal of Dabigatran-Associated Anticoagulation
Yogaratnam et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Idarucizumab, a specific reversal agent for dabigatran: mode of action, pharmacokinetics and pharmacodynamics, and safety and efficacy in phase 1 subjects
Reilly et al. · The American journal of emergency medicine
Added to ASH registry: 2026-05-28
Idarucizumab, a Specific Reversal Agent for Dabigatran: Mode of Action, Pharmacokinetics and Pharmacodynamics, and Safety and Efficacy in Phase 1 Subjects
Reilly et al. · The American journal of medicine
Added to ASH registry: 2026-05-28
Idarucizumab: A Review as a Reversal Agent for Dabigatran.
Syed · American journal of cardiovascular drugs : drugs, devices, and other interventions
Added to ASH registry: 2026-05-28
In vitro antithrombotic activities of peanut protein hydrolysates
Zhang SB · Food chemistry
Added to ASH registry: 2026-05-28
Incidence of venous thromboembolism in COPD: linking inflammation and thrombosis?
Lankeit et al. · The European respiratory journal
Added to ASH registry: 2026-05-28
Low dose heparin lock (1000 U/mL) maintains tunnelled hemodialysis catheter patency when compared with high dose heparin (5000 U/mL): A randomised controlled trial.
Chu et al. · Hemodialysis international. International Symposium on Home Hemodialysis
Added to ASH registry: 2026-05-28
Low-dose versus high-dose heparin locks for hemodialysis catheters: a systematic review and meta-analysis.
Han et al. · Clinical nephrology
Added to ASH registry: 2026-05-28
Managing transitions from oral factor Xa inhibitors to unfractionated heparin infusions
Faust et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Meta-Analysis of Effects of Bivalirudin Versus Heparin on Myocardial Ischemic and Bleeding Outcomes After Percutaneous Coronary Intervention.
Barria Perez et al. · The American journal of cardiology
Added to ASH registry: 2026-05-28
New Approaches to the Role of Thrombin in Acute Coronary Syndromes: Quo Vadis Bivalirudin, a Direct Thrombin Inhibitor?
Esteve-Pastor MA et al. · Molecules (Basel, Switzerland)
Added to ASH registry: 2026-05-28
Non-vitamin K antagonist oral anticoagulant reversal: hope is on the horizon.
Yorkgitis · American journal of surgery
Added to ASH registry: 2026-05-28
Novel oral anticoagulants for heparin-induced thrombocytopenia
Skelley JW et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Prolonged High-Dose Bivalirudin Infusion Reduces Major Bleeding Without Increasing Stent Thrombosis in Patients Undergoing Primary Percutaneous Coronary Intervention: Novel Insights From an Updated Meta-Analysis
Fahrni G et al. · Journal of the American Heart Association
Added to ASH registry: 2026-05-28
Reduced induction of anti-PF4/heparin antibody in RA patients after total knee arthroplasty
Izumi et al. · Arthritis research & therapy
Added to ASH registry: 2026-05-28
Reversal agents for use with direct and indirect anticoagulants.
Smythe et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Reversal of dabigatran by idarucizumab: when and how?.
Vanassche et al. · Expert review of hematology
Added to ASH registry: 2026-05-28
Reversing anticoagulant effects of novel oral anticoagulants: role of ciraparantag, andexanet alfa, and idarucizumab.
Hu et al. · Vascular health and risk management
Added to ASH registry: 2026-05-28
Risk-guided use of the direct thrombin inhibitor bivalirudin
Hillegass et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-28
Rivaroxaban in treatment refractory heparin-induced thrombocytopenia
Casan et al. · BMJ case reports
Added to ASH registry: 2026-05-28
Rivaroxaban limits complement activation compared with warfarin in antiphospholipid syndrome patients with venous thromboembolism.
Arachchillage DRJ et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial.
Cohen H et al. · The Lancet. Haematology
Added to ASH registry: 2026-05-28
Spotlight on idarucizumab and its potential for the reversal of anticoagulant effects of dabigatran.
Sié · Drug design, development and therapy
Added to ASH registry: 2026-05-28
Structural and functional aspects of decorsin and its analog as recognized by integrin αIIbβ3.
Lao X et al. · Journal of molecular modeling
Added to ASH registry: 2026-05-28
Substrate-Guided Design of Selective FXIIa Inhibitors Based on the Plant-Derived Momordica cochinchinensis Trypsin Inhibitor-II (MCoTI-II) Scaffold
Swedberg et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
The Coagulation Factor XIIa Inhibitor rHA-Infestin-4 Improves Outcome after Cerebral Ischemia/Reperfusion Injury in Rats
Krupka et al. · PloS one
Added to ASH registry: 2026-05-28
The discovery of dabigatran etexilate for the treatment of venous thrombosis
Feuring et al. · Expert opinion on drug discovery
Added to ASH registry: 2026-05-28
The effect of the direct factor Xa inhibitors apixaban and rivaroxaban on haemostasis tests: a comprehensive assessment using in vitro and ex vivo samples
Bonar R et al. · Pathology
Added to ASH registry: 2026-05-28
The effects of bivalirudin vs heparin on short-term outcomes in patients undergoing percutaneous coronary intervention.
Palla et al. · International journal of cardiology
Added to ASH registry: 2026-05-28
The past and future of haemophilia: diagnosis, treatments, and its complications.
Peyvandi F et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
The safety of fondaparinux sodium for the treatment of venous thromboembolism
Mastroiacovo D et al. · Expert opinion on drug safety
Added to ASH registry: 2026-05-28
Transradial access mitigates bleeding benefit offered by bivalirudin over heparin in patients undergoing percutaneous coronary intervention: Insights from meta-analysis of randomized and observational studies
Pasala T et al. · International journal of cardiology
Added to ASH registry: 2026-05-28
Use of Extracorporeal Techniques in the Removal of Dabigatran
Muddana et al. · American journal of therapeutics
Added to ASH registry: 2026-05-28
Von Willebrand's Disease.
Leebeek FWG et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
A novel hirudin derivative inhibiting thrombin without bleeding for subcutaneous injection
Zhao B et al. · Thrombosis and Haemostasis
Added to ASH registry: 2026-05-27
Argatroban pharmacokinetics and pharmacodynamics in critically ill cardiac surgical patients with suspected heparin-induced thrombocytopenia
Keyl C et al. · Thrombosis and Haemostasis
Added to ASH registry: 2026-05-27
Assessing the cardiology community position on transradial intervention and the use of bivalirudin in patients with acute coronary syndrome undergoing invasive management: results of an EAPCI survey
Adamo M et al. · EuroIntervention
Added to ASH registry: 2026-05-27
Bivalirudin and the Matrix Trial: The End of the Story?
De Luca G et al. · Curr Vasc Pharmacol
Added to ASH registry: 2026-05-27
Bivalirudin Anticoagulation for a Pediatric Patient with Heparin-Induced Thrombocytopenia and Thrombosis Requiring Cardiopulmonary Bypass for Ventricular Assist Device Placement
Faella KH et al. · The journal of extra-corporeal technology
Added to ASH registry: 2026-05-27
Bivalirudin for Alternative Anticoagulation in Extracorporeal Membrane Oxygenation: A Systematic Review
Sanfilippo F et al. · Journal of intensive care medicine
Added to ASH registry: 2026-05-27
Bivalirudin or unfractionated heparin in patients with acute coronary syndromes managed invasively with and without ST elevation (MATRIX): randomised controlled trial
Leonardi S et al. · BMJ
Added to ASH registry: 2026-05-27
Characterisation of separated end hyaluronan oligosaccharides from leech hyaluronidase and evaluation of angiogenesis
Lv M et al. · Carbohydr Polym
Added to ASH registry: 2026-05-27
Chinese Medicinal Leech: Ethnopharmacology, Phytochemistry, and Pharmacological Activities
Dong H et al. · Evidence-based complementary and alternative medicine
Added to ASH registry: 2026-05-27
Combinatorial Evolution of Enzymes and Synthetic Pathways Using One-Step PCR
Jin P et al. · ACS Synthetic Biology
Added to ASH registry: 2026-05-27
Combined Use of Bivalirudin and Radial Access in Acute Coronary Syndromes IsNot Superior to the Use of Either OneSeparately: Meta-Analysis of Randomized Controlled Trials
Mina GS et al. · JACC. Cardiovascular interventions
Added to ASH registry: 2026-05-27
Comparison of heparin, bivalirudin, and different glycoprotein IIb/IIIa inhibitor regimens for anticoagulation during percutaneous coronary intervention: A network meta-analysis
Lipinski MJ et al. · Cardiovascular revascularization medicine : including molecular interventions
Added to ASH registry: 2026-05-27
Dabigatran approaching the realm of heparin-induced thrombocytopenia
Ho PJ et al. · Blood research
Added to ASH registry: 2026-05-27
Development of a predictive nomogram for the change in PT/INR upon discontinuation of bivalirudin as a bridge to warfarin
Hohlfelder B et al. · Clinical and applied thrombosis/hemostasis
Added to ASH registry: 2026-05-27
Direct Thrombin Inhibitor for LVAD Thrombosis: A Closer Look
Rimsans J et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-27
Early Stent Thrombosis and Mortality After Primary Percutaneous Coronary Intervention in ST-Segment-Elevation Myocardial Infarction: A Patient-Level Analysis of 2 Randomized Trials
Dangas GD et al. · Circ Cardiovasc Interv
Added to ASH registry: 2026-05-27
Effect of post-primary percutaneous coronary intervention bivalirudin infusion on net adverse clinical events and mortality: A comprehensive pairwise and network meta-analysis of randomized controlled trials
Shah R et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-27
Efficiency and safety of bivalirudin in patients undergoing emergency percutaneous coronary intervention via radial access: A subgroup analysis from the bivalirudin in acute myocardial infarction versus heparin and GPI plus heparin trial
Wang H et al. · Catheter Cardiovasc Interv
Added to ASH registry: 2026-05-27
Exploiting the antithrombotic effect of the (pro)thrombin inhibitor bothrojaracin
Assafim M et al. · Toxicon
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia in cardiac surgery and critically ill patients
Selleng S, Selleng K · Thrombosis and Haemostasis
Added to ASH registry: 2026-05-27
Heparin-induced Thrombocytopenia Presenting With Deep Venous Thrombosis and Pulmonary Embolism Successfully Treated With Rivaroxaban
Samos M et al. · Journal of cardiovascular pharmacology
Added to ASH registry: 2026-05-27
Hirudins and hirudin-like factors in Hirudinidae: implications for function and phylogenetic relationships
Mller C et al. · Parasitology research
Added to ASH registry: 2026-05-27
Identification and characterization of novel anticoagulant peptide with thrombolytic effect and nutrient oligopeptides with high branched chain amino acid from Whitmania pigra protein
Ren Y et al. · Amino Acids
Added to ASH registry: 2026-05-27
In vitro anticoagulant activity of different processed products of Whitmania pigra by water extraction and bionic extraction
Shan Y et al. · Zhongguo Zhong yao za zhi
Added to ASH registry: 2026-05-27
Intracoronary Bivalirudin Bolus in ST-Elevation Myocardial Infarction Patients Treated with Primary Angioplasty: Theoretical Bases, Clinical Experience, and Future Applications
Lupi A et al. · American Journal of Cardiovascular Drugs
Added to ASH registry: 2026-05-27
Pharmacological effects and pharmacokinetic properties of a dual-function peptide 5rolGLP-HV
Ni Z et al. · Applied biochemistry and biotechnology
Added to ASH registry: 2026-05-27
Potential mechanism of acute stent thrombosis with bivalirudin following percutaneous coronary intervention in acute coronary syndromes
Laine M et al. · International journal of cardiology
Added to ASH registry: 2026-05-27
Production of specific-molecular-weight hyaluronan by metabolically engineered Bacillus subtilis 168
Jin P et al. · Metabolic Engineering
Added to ASH registry: 2026-05-27
Safety and Efficacy of Bivalirudin in Patients With Diabetes Mellitus Undergoing Percutaneous Coronary Intervention: From the REPLACE-2, ACUITY and HORIZONS-AMI Trials
Giustino G et al. · Am J Cardiol
Added to ASH registry: 2026-05-27
The Coagulant Factor Xa Induces Protease-Activated Receptor-1 and Annexin A2-Dependent Airway Smooth Muscle Cytokine Production and Cell Proliferation
Schuliga M et al. · American journal of respiratory cell and molecular biology
Added to ASH registry: 2026-05-27
The IL-1 cytokine family and its role in inflammation and fibrosis in the lung
Borthwick LA · Seminars in immunopathology
Added to ASH registry: 2026-05-27
The safety and effectiveness of bivalirudin in female patients with acute myocardial infarction undergoing primary angioplasty: A subgroup analysis of the BRIGHT trial
Liang Z et al. · Catheter Cardiovasc Interv
Added to ASH registry: 2026-05-27
[Pulmonary embolism].
Hecker et al. · Medizinische Klinik, Intensivmedizin und Notfallmedizin
Added to ASH registry: 2026-05-28
A Synthetic Factor XIIa Inhibitor Blocks Selectively Intrinsic Coagulation Initiation
Baeriswyl et al. · ACS chemical biology
Added to ASH registry: 2026-05-28
Allosteric inhibition of factor XIa. Sulfated non-saccharide glycosaminoglycan mimetics as promising anticoagulants
Al-Horani et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity
Siegal DM et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Anticoagulants in children and adolescents
Young et al. · Hematology. American Society of Hematology. Education Program
Added to ASH registry: 2026-05-28
Apixaban in Venous Thromboembolism in an Era of New Oral Anticoagulants
Turagam et al. · Cardiovascular & hematological disorders drug targets
Added to ASH registry: 2026-05-28
Argatroban in the management of heparin-induced thrombocytopenia: a multicenter clinical trial
Tardy-Poncet et al. · Critical care (London, England)
Added to ASH registry: 2026-05-28
Benefit-risk profile of non-vitamin K antagonist oral anticoagulants in the management of venous thromboembolism
Beyer-Westendorf J et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Biological protein-resistance layer construction of recombinant hirudin on polymethyl methacrylate IOL surface
Zheng et al. · Journal of biomedical materials research. Part A
Added to ASH registry: 2026-05-28
Bivalirudin Anticoagulant Therapy With or Without Platelet Glycoprotein IIb/IIIa Inhibitors During Transcatheter Coronary Interventional Procedures: A Meta-Analysis.
Li et al. · Medicine
Added to ASH registry: 2026-05-28
Bivalirudin as an Alternative to Heparin for Anticoagulation in Infants and Children.
Buck · The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
Added to ASH registry: 2026-05-28
Bivalirudin in percutaneous coronary intervention, is it the anticoagulant of choice?
Mahmoud A et al. · Cardiovascular therapeutics
Added to ASH registry: 2026-05-28
Bivalirudin in stable angina and acute coronary syndromes
Mavrakanas et al. · Pharmacology & therapeutics
Added to ASH registry: 2026-05-28
Bivalirudin versus heparin in patients treated with percutaneous coronary intervention: a meta-analysis of randomised trials
Cassese S et al. · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Added to ASH registry: 2026-05-28
Bivalirudin versus heparin in patients with acute myocardial infarction: A meta-analysis of randomized trials
Ferrante et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-28
Catheter-directed thrombolysis for extensive iliofemoral deep vein thrombosis: review of literature and ongoing trials.
Liew A et al. · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-28
Changing practice of anticoagulation: will target-specific anticoagulants replace warfarin?
Arepally GM et al. · Annual review of medicine
Added to ASH registry: 2026-05-28
Chronic thromboembolic pulmonary hypertension: the evolving treatment landscape.
Kim NH et al. · European respiratory review : an official journal of the European Respiratory Society
Added to ASH registry: 2026-05-28
Chronic thromboembolic pulmonary hypertension.
O'Connell C et al. · Presse medicale (Paris, France : 1983)
Added to ASH registry: 2026-05-28
Comparing sixteen scoring functions for predicting biological activities of ligands for protein targets.
Xu W et al. · Journal of molecular graphics & modelling
Added to ASH registry: 2026-05-28
Comparison of the Novel Oral Anticoagulants Apixaban, Dabigatran, Edoxaban, and Rivaroxaban in the Initial and Long-Term Treatment and Prevention of Venous Thromboembolism: Systematic Review and Network Meta-Analysis
Cohen et al. · PloS one
Added to ASH registry: 2026-05-28
Conserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions.
Kim TK et al. · International journal for parasitology
Added to ASH registry: 2026-05-28
Critical Appraisal of Bivalirudin versus Heparin for Percutaneous Coronary Intervention: A Meta-Analysis of Randomized Trials
Bavry AA et al. · PloS one
Added to ASH registry: 2026-05-28
Current and emerging strategies in the management of venous thromboembolism: benefit-risk assessment of dabigatran
Fanola CL · Vascular health and risk management
Added to ASH registry: 2026-05-28
Current management of heparin-induced thrombocytopenia.
Cosmi · Expert review of hematology
Added to ASH registry: 2026-05-28
Dabigatran for the prevention and treatment of thromboembolic disorders
Enriquez et al. · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-28
Dabigatran for the treatment of venous thromboembolism
Schellong et al. · Expert review of hematology
Added to ASH registry: 2026-05-28
Direct factor Xa inhibitor edoxaban: from bench to clinical practice
Brekelmans et al. · Expert review of hematology
Added to ASH registry: 2026-05-28
Direct factor Xa inhibitors (rivaroxaban and apixaban) versus enoxaparin for the prevention of venous thromboembolism after total knee replacement: A meta-analysis of 6 randomized clinical trials
Ma G et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Discovery of novel antagonists of glycoprotein IIb/IIIa-mediated platelet aggregation through virtual screening
Wang et al. · Bioorganic & medicinal chemistry letters
Added to ASH registry: 2026-05-28
Disseminated intravascular coagulation in pregnancy: insights in pathophysiology, diagnosis and management.
Erez et al. · American journal of obstetrics and gynecology
Added to ASH registry: 2026-05-28
Dose tailoring of dabigatran etexilate: obvious or excessive?
Douxfils et al. · Expert opinion on drug safety
Added to ASH registry: 2026-05-28
Early stent thrombosis with bivalirudin in patients undergoing percutaneous coronary intervention. A meta-analysis of randomised clinical trials
Piccolo R et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Edoxaban, a Novel Oral Factor Xa Inhibitor
Minor et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Edoxaban: a review in nonvalvular atrial fibrillation
McCormack · American journal of cardiovascular drugs : drugs, devices, and other interventions
Added to ASH registry: 2026-05-28
Efficacy of argatroban in critically ill patients with heparin resistance: a retrospective analysis
Treichl et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Enhanced elimination of dabigatran through extracorporeal methods
Awad et al. · Journal of medical toxicology : official journal of the American College of Medical Toxicology
Added to ASH registry: 2026-05-28
Evaluation of 2 nomogram-based strategies for dosing argatroban in patients with known or suspected heparin-induced thrombocytopenia
Arpino et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Evaluation of a multi-target direct thrombin inhibitor dosing and titration guideline for patients with suspected heparin-induced thrombocytopenia
Gilmore et al. · American journal of hematology
Added to ASH registry: 2026-05-28
Factors Affecting Bleeding and Stent Thrombosis in Clinical Trials Comparing Bivalirudin With Heparin During Percutaneous Coronary Intervention
Bittl JA et al. · Circulation. Cardiovascular interventions
Added to ASH registry: 2026-05-28
Fasxiator, a novel factor XIa inhibitor from snake venom, and its site-specific mutagenesis to improve potency and selectivity
Chen et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Fondaparinux for Management of Heparin-induced Thrombocytopenia after Cardiovascular Intervention: A Systematic Review
Bhatt et al. · Cardiovascular & hematological agents in medicinal chemistry
Added to ASH registry: 2026-05-28
Fondaparinux in pregnancy: Could it be a safe option? A review of the literature
De et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Heparin induced thrombocytopenia. Contemporary therapeutic approaches in light of the new oral anticoagulants
Sanidas EA et al. · Hamostaseologie
Added to ASH registry: 2026-05-28
Heparin is Not Inferior to Bivalirudin in Percutaneous Coronary Intervention-Focusing on the Effect of Glycoprotein IIb/IIIa Inhibitor Use: A Meta-Analysis
Huang FY et al. · Angiology
Added to ASH registry: 2026-05-28
Idarucizumab for Dabigatran Reversal
Pollack et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Idarucizumab, a Humanized, Monoclonal Antibody Fragment for Immediate Reversal of Dabigatran
Miyares et al. · Journal of pharmacy practice
Added to ASH registry: 2026-05-28
Idarucizumab: The Antidote for Reversal of Dabigatran
Eikelboom et al. · Circulation
Added to ASH registry: 2026-05-28
In vitro, antithrombotic and bleeding time studies of BMS-654457, a small-molecule, reversible and direct inhibitor of factor XIa
Wong et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Laboratory testing for platelet function disorders.
Israels · International journal of laboratory hematology
Added to ASH registry: 2026-05-28
Left atrial appendage occlusion for prevention of stroke in nonvalvular atrial fibrillation: a meta-analysis.
Bode WD et al. · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
Added to ASH registry: 2026-05-28
Left atrial appendage occlusion in atrial fibrillation for stroke prevention: A systemic review.
Zhou X et al. · International journal of cardiology
Added to ASH registry: 2026-05-28
Limitation of the activated partial thromboplastin time as a monitoring method of the direct thrombin inhibitor argatroban
Guy et al. · International journal of laboratory hematology
Added to ASH registry: 2026-05-28
LX0702, a novel snake venom peptide derivative, inhibits thrombus formation via affecting the binding of fibrinogen with GPIIb/IIIa
Kong Y et al. · Journal of pharmacological sciences
Added to ASH registry: 2026-05-28
Managing target-specific oral anticoagulant associated bleeding including an update on pharmacological reversal agents.
Siegal · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Meta-analysis of dabigatran vs warfarin in patients undergoing catheter ablation for atrial fibrillation
Phan et al. · International journal of cardiology
Added to ASH registry: 2026-05-28
New anticoagulants in the management of venous thromboembolism in women
Piovella F et al. · Thrombosis research
Added to ASH registry: 2026-05-28
New oral anticoagulants in the treatment of heparin-induced thrombocytopenia
Sharifi et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Oral direct factor Xa inhibitor versus enoxaparin for thromboprophylaxis after hip or knee arthroplasty: Systemic review, traditional meta-analysis, dose-response meta-analysis and network meta-analysis
Feng et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of deep vein thrombosis
Robertson et al. · The Cochrane database of systematic reviews
Added to ASH registry: 2026-05-28
Plasmin regulation through allosteric, sulfated, small molecules.
Al-Horani RA et al. · Molecules (Basel, Switzerland)
Added to ASH registry: 2026-05-28
Relation between dabigatran concentration, as assessed using the direct thrombin inhibitor assay, and activated clotting time/activated partial thromboplastin time in patients with atrial fibrillation
Okubo et al. · The American journal of cardiology
Added to ASH registry: 2026-05-28
Reversal of anticoagulant effects in patients with intracerebral hemorrhage.
Yates et al. · Current neurology and neuroscience reports
Added to ASH registry: 2026-05-28
Rivaroxaban for the treatment of cerebral venous thrombosis
Mutgi et al. · International journal of stroke : official journal of the International Stroke Society
Added to ASH registry: 2026-05-28
Safety and efficacy of oral direct inhibitors of thrombin and factor Xa in antiphospholipid syndrome
Noel N et al. · Autoimmunity reviews
Added to ASH registry: 2026-05-28
Screening of direct thrombin inhibitors from Radix Salviae Miltiorrhizae by a peak fractionation approach
Lu et al. · Journal of pharmaceutical and biomedical analysis
Added to ASH registry: 2026-05-28
Selective disruption of heparin and antithrombin-mediated regulation of human factor IX.
Westmark PR et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Short- and long-term outcomes in diabetes patients undergoing percutaneous coronary intervention with bivalirudin compared with heparin and glycoprotein IIb/IIIA inhibitors: A meta-analysis of randomized trials
Nairooz R et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-28
Splanchnic Vein Thrombosis.
Valla · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Superficial vein thrombosis: a current approach to management
Scott et al. · British journal of haematology
Added to ASH registry: 2026-05-28
The association of direct thrombin inhibitor anticoagulants with cardiac thromboses
Davidson BL · Chest
Added to ASH registry: 2026-05-28
Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma induced coagulopathy in adult trauma patients with bleeding.
Hunt et al. · The Cochrane database of systematic reviews
Added to ASH registry: 2026-05-28
Tissue Factor Pathway Inhibitor: Multiple Anticoagulant Activities for a Single Protein.
Mast · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-28
Tonsillectomy on rivaroxaban
Saini et al. · American journal of otolaryngology
Added to ASH registry: 2026-05-28
Uninterrupted rivaroxaban vs. uninterrupted vitamin K antagonists for catheter ablation in non-valvular atrial fibrillation.
Cappato R et al. · European heart journal
Added to ASH registry: 2026-05-28
A novel stearic acid-modified hirudin peptidomimetic with improved pharmacokinetic properties and anticoagulant activity
Liu Z et al. · Scientific Reports
Added to ASH registry: 2026-05-27
Bivalirudin as compared to unfractionated heparin in patients undergoing percutaneous coronary revascularization: A meta-analysis of 22 randomized trials
Verdoia M et al. · Thrombosis research
Added to ASH registry: 2026-05-27
Bivalirudin or Unfractionated Heparin in Acute Coronary Syndromes
Valgimigli M et al. · N Engl J Med
Added to ASH registry: 2026-05-27
Bivalirudin versus heparin with or without glycoprotein IIb/IIIa inhibitors in patients with STEMI undergoing primary percutaneous coronary intervention: pooled patient-level analysis from the HORIZONS-AMI and EUROMAX trials
Stone GW et al. · J Am Coll Cardiol
Added to ASH registry: 2026-05-27
Bothrops jararaca envenomation: Pathogenesis of hemostatic disturbances and intravascular hemolysis
Senise LV et al. · Experimental biology and medicine
Added to ASH registry: 2026-05-27
Challenging Argatroban Management of a Child on Extracorporeal Support and Subsequent Heart Transplant
Latham GJ et al. · Seminars in cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-27
Comparison of bivalirudin to lepirudin and argatroban in patients with heparin-induced thrombocytopenia
Bain J et al. · American journal of health-system pharmacy
Added to ASH registry: 2026-05-27
Enhanced production of leech hyaluronidase by optimizing secretion and cultivation in Pichia pastoris
Kang Z et al. · Appl Microbiol Biotechnol
Added to ASH registry: 2026-05-27
Enzymatic production of specifically distributed hyaluronan oligosaccharides
Yuan P et al. · Carbohydr Polym
Added to ASH registry: 2026-05-27
Heparin-Induced Thrombocytopenia in a Patient with Essential Thrombocythemia: A Case Based Update
Noel E et al. · Case reports in hematology
Added to ASH registry: 2026-05-27
Impact of anticoagulation regimen prior to revascularization in patients with non-ST-segment elevation acute coronary syndromes: The ACUITY trial
Geisler T et al. · Catheter Cardiovasc Interv
Added to ASH registry: 2026-05-27
Impact of Bleeding and Bivalirudin Therapy on Mortality Risk in Women Undergoing Percutaneous Coronary Intervention (from the REPLACE-2, ACUITY, and HORIZONS-AMI Trials)
Ng VG et al. · Am J Cardiol
Added to ASH registry: 2026-05-27
Improving the bioactivity of rHirudin with boronophenylalanine site-specific modification
Xin X et al. · Molecular medicine reports
Added to ASH registry: 2026-05-27
Is routine post-procedural anticoagulation warranted after primary percutaneous coronary intervention in ST-segment elevation myocardial infarction? Insights from the HORIZONS-AMI trial
Madhavan MV et al. · European heart journal. Acute cardiovascular care
Added to ASH registry: 2026-05-27
Management and Outcome of Heparin-Induced Thrombocytopenia in Pregnancy: A Systematic Review
Chaudhary RK et al. · Cardiovascular & hematological agents in medicinal chemistry
Added to ASH registry: 2026-05-27
Plasma exchange on venovenous extracorporeal membrane oxygenation with bivalirudin anticoagulation
Preston TJ et al. · World journal for pediatric & congenital heart surgery
Added to ASH registry: 2026-05-27
Rational design of stable and functional hirudin III mutants with lower antigenicity
Asgari S et al. · Biologicals : journal of the International Association of Biological Standardization
Added to ASH registry: 2026-05-27
Re-infarction after primary percutaneous coronary intervention
French JK et al. · Current opinion in cardiology
Added to ASH registry: 2026-05-27
Successful use of a bivalirudin treatment protocol to prevent extracorporeal thrombosis in ambulatory hemodialysis patients with heparin-induced thrombocytopenia
Al-Ali FS et al. · Hemodialysis international
Added to ASH registry: 2026-05-27
Hirudotherapy in Medicine and Dentistry
Jha K et al. · Journal of clinical and diagnostic research : JCDR
Added to ASH registry: 2026-03-18
Frequent off-label use of fondaparinux in patients with suspected acute heparin-induced thrombocytopenia (HIT)--findings from the GerHIT multi-centre registry study
Schindewolf et al. · Thrombosis research
Added to ASH registry: 2026-05-29
A new peptide (Ruviprase) purified from the venom of Daboia russelii russelii shows potent anticoagulant activity via non-enzymatic inhibition of thrombin and factor Xa
Thakur R et al. · Biochimie
Added to ASH registry: 2026-05-28
A novel Toll like receptor with two TIR domains (HcToll-2) is involved in regulation of antimicrobial peptide gene expression of Hyriopsis cumingii.
Ren Q et al. · Developmental and comparative immunology
Added to ASH registry: 2026-05-28
A simple, general approach of allosteric coagulation enzyme inhibition through monosulfated hydrophobic scaffolds.
Sidhu PS et al. · Bioorganic & medicinal chemistry letters
Added to ASH registry: 2026-05-28
Acute coagulopathy in pediatric trauma.
Choi et al. · Current opinion in pediatrics
Added to ASH registry: 2026-05-28
Advantages and limitations of the new anticoagulants
Schulman S · Journal of internal medicine
Added to ASH registry: 2026-05-28
Anticoagulation and antiplatelet therapy in acute coronary syndromes
Singh et al. · Cleveland Clinic journal of medicine
Added to ASH registry: 2026-05-28
Antithrombotic activities of sulforaphane via inhibiting platelet aggregation and FIIa/FXa
Ku SK et al. · Archives of pharmacal research
Added to ASH registry: 2026-05-28
Argatroban, a new antithrombotic treatment for heparin-induced thrombocytopenia application in cardiac surgery and in intensive care
Rozec B et al. · Annales francaises d'anesthesie et de reanimation
Added to ASH registry: 2026-05-28
Benefit-risk assessment of dabigatran in the treatment of stroke prevention in non-valvular atrial fibrillation
Meyer et al. · Drug safety
Added to ASH registry: 2026-05-28
Bivalirudin versus heparin in patients planned for percutaneous coronary intervention: a meta-analysis of randomised controlled trials
Cavender MA et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
Chronic thromboembolic pulmonary hypertension.
Hoeper MM et al. · The Lancet. Respiratory medicine
Added to ASH registry: 2026-05-28
Chronic thromboembolic pulmonary hypertension.
Olsson KM et al. · Deutsches Arzteblatt international
Added to ASH registry: 2026-05-28
Clinical pharmacokinetic and pharmacodynamic profile of rivaroxaban.
Mueck W et al. · Clinical pharmacokinetics
Added to ASH registry: 2026-05-28
Clinical utility of apixaban in the prevention and treatment of venous thromboembolism: current evidence
Zalpour et al. · Drug design, development and therapy
Added to ASH registry: 2026-05-28
Comparison of the effect of edoxaban, a direct factor Xa inhibitor, with a direct thrombin inhibitor, melagatran, and heparin on intracerebral hemorrhage induced by collagenase in rats
Shirasaki et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Contemporary anticoagulation therapy in patients undergoing percutaneous intervention.
Bhatty et al. · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-28
Dabigatran etexilate and risk of myocardial infarction, other cardiovascular events, major bleeding, and all-cause mortality: a systematic review and meta-analysis of randomized controlled trials
Douxfils et al. · Journal of the American Heart Association
Added to ASH registry: 2026-05-28
Dabigatran etexilate for venous thromboembolism: a safety evaluation
Brown et al. · Expert opinion on drug safety
Added to ASH registry: 2026-05-28
Dabigatran etexilate: a review of its use in the treatment of acute venous thromboembolism and prevention of venous thromboembolism recurrence
Greig et al. · Drugs
Added to ASH registry: 2026-05-28
Designing allosteric inhibitors of factor XIa. Lessons from the interactions of sulfated pentagalloylglucopyranosides.
Al-Horani RA et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Drug-induced immune thrombocytopenia
Kam T et al. · Journal of pharmacy practice
Added to ASH registry: 2026-05-28
Edoxaban: a focused review of its clinical pharmacology
Lip et al. · European heart journal
Added to ASH registry: 2026-05-28
Edoxaban: Review of pharmacology and key phase I to III clinical trials
Plitt et al. · Journal of cardiovascular pharmacology and therapeutics
Added to ASH registry: 2026-05-28
Effect of thromboelastography (TEG®) and rotational thromboelastometry (ROTEM®) on diagnosis of coagulopathy, transfusion guidance and mortality in trauma: descriptive systematic review.
Da Luz et al. · Critical care (London, England)
Added to ASH registry: 2026-05-28
Effects of the oral, direct factor Xa inhibitor apixaban on routine coagulation assays and anti-FXa assays
Hillarp A et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Ensemble refinement shows conformational flexibility in crystal structures of human complement factor D.
Forneris F et al. · Acta crystallographica. Section D, Biological crystallography
Added to ASH registry: 2026-05-28
Feasibility and safety of uninterrupted rivaroxaban for periprocedural anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from a multicenter prospective registry.
Lakkireddy D et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
Global coagulation tests: their applicability for measuring direct factor Xa- and thrombin inhibition and reversal of anticoagulation by prothrombin complex concentrate
Dinkelaar J et al. · Clinical chemistry and laboratory medicine
Added to ASH registry: 2026-05-28
Glycoprotein IIb/IIIa inhibitors increase bleeding: the elephant in the cardiac catheterization laboratory.
Gaglia · Cardiovascular revascularization medicine : including molecular interventions
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia and the health economic analysis of argatroban
Coventry et al. · British journal of anaesthesia
Added to ASH registry: 2026-05-28
Inhibition of ADP-induced platelet aggregation and involvement of non-cellular blood chemical mediators are responsible for the antithrombotic potential of the fruits of Lagenaria siceraria
Rajput et al. · Chinese journal of natural medicines
Added to ASH registry: 2026-05-28
Laboratory monitoring of the non-vitamin K oral anticoagulants
Blann AD et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
Left atrial appendage occlusion with the WATCHMAN™ for stroke prevention in atrial fibrillation.
Price MJ · Reviews in cardiovascular medicine
Added to ASH registry: 2026-05-28
Mechanical thrombectomy in acute ischemic stroke-experience from 6 years of practice.
Kuntze Söderqvist et al. · Neuroradiology
Added to ASH registry: 2026-05-28
Meta-analysis of randomized clinical trials comparing bivalirudin versus heparin plus glycoprotein IIb/IIIa inhibitors in patients undergoing percutaneous coronary intervention and in patients with ST-segment elevation myocardial infarction
Nairooz R et al. · The American journal of cardiology
Added to ASH registry: 2026-05-28
Monitoring and reversal strategies for new oral anticoagulants.
Vanden Daelen et al. · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-28
Multiple inhibitory kinetics reveal an allosteric interplay among thrombin functional sites.
Zavyalova E et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Natural inhibitors of thrombin
Huntington · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Pharmacokinetics and pharmacodynamics of rivaroxaban--an oral, direct factor Xa inhibitor
Kreutz et al. · Current clinical pharmacology
Added to ASH registry: 2026-05-28
Pharmacologic and clinical characteristics of direct inhibitors of factor Xa: rivaroxaban, apixaban, edoxaban and betrixaban
Meddahi S et al. · Journal des maladies vasculaires
Added to ASH registry: 2026-05-28
Polyphenol compounds belonging to flavonoids inhibit activity of coagulation factor X.
Bijak M et al. · International journal of biological macromolecules
Added to ASH registry: 2026-05-28
Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial.
Holmes DR et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
Race against the clock: overcoming challenges in the management of anticoagulant-associated intracerebral hemorrhage.
Le Roux et al. · Journal of neurosurgery
Added to ASH registry: 2026-05-28
Reduced-dose warfarin or interrupted warfarin with heparin bridging for pacemaker or defibrillator implantation: a randomized trial.
Schulman S et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Riociguat for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
Bishop BM · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Rivaroxaban: a review of its use in the treatment of deep vein thrombosis or pulmonary embolism and the prevention of recurrent venous thromboembolism
Burness et al. · Drugs
Added to ASH registry: 2026-05-28
Safety of continuous periprocedural rivaroxaban for patients undergoing left atrial catheter ablation procedures.
Dillier R et al. · Circulation. Arrhythmia and electrophysiology
Added to ASH registry: 2026-05-28
Targeting the GPIbα binding site of thrombin to simultaneously induce dual anticoagulant and antiplatelet effects.
Mehta AY et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
The acute management of haemorrhage, surgery and overdose in patients receiving dabigatran
Alikhan et al. · Emergency medicine journal : EMJ
Added to ASH registry: 2026-05-28
The dosing and monitoring of argatroban for heparin-induced thrombocytopenia during extracorporeal membrane oxygenation: a word of caution
Phillips et al. · Anaesthesia and intensive care
Added to ASH registry: 2026-05-28
Ultrasound-assisted thrombolysis for acute pulmonary embolism: a systematic review.
Engelberger RP et al. · European heart journal
Added to ASH registry: 2026-05-28
Von Willebrand disease.
Cooper S et al. · Pediatrics in review
Added to ASH registry: 2026-05-28
Aqueous leaf extract of Jatropha gossypiifolia L. inhibits enzymatic and biological actions of Bothrops jararaca snake venom
Felix-Silva J et al. · PloS one
Added to ASH registry: 2026-05-27
Argatroban versus Lepirudin in critically ill patients (ALicia): a randomized controlled trial
Treschan TA et al. · Critical Care
Added to ASH registry: 2026-05-27
Bivalirudin for acute coronary syndromes: premises, promises and doubts
Capodanno D et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Bivalirudin versus heparin for percutaneous coronary intervention: an updated meta-analysis of randomized controlled trials
Lipinski MJ et al. · Cardiovascular revascularization medicine : including molecular interventions
Added to ASH registry: 2026-05-27
Comparison of prasugrel and bivalirudin vs clopidogrel and heparin in patients with ST-segment elevation myocardial infarction: Design and rationale of the Bavarian Reperfusion Alternatives Evaluation (BRAVE) 4 trial
Schulz S et al. · Clin Cardiol
Added to ASH registry: 2026-05-27
Comprehensive meta-analysis of safety and efficacy of bivalirudin versus heparin with or without routine glycoprotein IIb/IIIa inhibitors in patients with acute coronary syndrome
Navarese EP et al. · JACC. Cardiovascular interventions
Added to ASH registry: 2026-05-27
Design and rationale for the Minimizing Adverse haemorrhagic events by TRansradial access site and systemic Implementation of angioX program
Valgimigli M et al. · American heart journal
Added to ASH registry: 2026-05-27
Direct thrombin inhibitors: patents 2002-2012
Kong Y et al. · Molecular medicine reports
Added to ASH registry: 2026-05-27
Emerging therapy options in heparin-induced thrombocytopenia
Chaudhary RK et al. · Cardiovascular & Hematological Agents in Medicinal Chemistry
Added to ASH registry: 2026-05-27
GILZ: a new link between the hypothalamic pituitary adrenal axis and rheumatoid arthritis?
Eades LE et al. · Immunology and cell biology
Added to ASH registry: 2026-05-27
Highly active fractions of the medicinal leech recombinant destabilase-lysozyme
Fadeeva IY et al. · Biomeditsinskaia khimiia
Added to ASH registry: 2026-05-27
Identification of lactoferrin as a human dedifferentiation factor through the studies of reptile tissue regeneration mechanisms
Bae KS et al. · Journal of microbiology and biotechnology
Added to ASH registry: 2026-05-27
Intraspecific differences in the immunochemical reactivity and neutralization of venom from Argentinean Bothrops alternatus by specific experimental antivenoms
Lanari LC et al. · Toxicon
Added to ASH registry: 2026-05-27
Morphological and molecular characterization of a new species of leech (Glossiphoniidae, Hirudinida): Implications for the health of its imperiled amphibian host (Cryptobranchus alleganiensis)
Hopkins WA et al. · ZooKeys
Added to ASH registry: 2026-05-27
MULTInational non-interventional study of patients with ST-segment elevation myocardial infarction treated with PRimary Angioplasty and Concomitant use of upstream antiplatelet therapy with prasugrel or clopidogrel--the European MULTIPRAC Registry
Clemmensen P et al. · European heart journal. Acute cardiovascular care
Added to ASH registry: 2026-05-27
Oversulfated chondroitin sulfate binds to chemokines and inhibits stromal cell-derived factor-1 mediated signaling in activated T cells
Zhou ZH et al. · PloS one
Added to ASH registry: 2026-05-27
Prognostic value of angiographic lesion complexity in patients with acute coronary syndromes undergoing percutaneous coronary intervention (from the acute catheterization and urgent intervention triage strategy trial)
Goto K et al. · The American journal of cardiology
Added to ASH registry: 2026-05-27
Safety of desirudin in thrombosis prevention after total knee arthroplasty: the DESIR-ABLE study
Jove M et al. · American journal of therapeutics
Added to ASH registry: 2026-05-27
Scientific foundation and possible implications for practice of the Minimizing Adverse Haemorrhagic Events by Transradial Access Site andSystemic Implementation of AngioX (MATRIX) trial
Valgimigli M et al. · Journal of cardiovascular translational research
Added to ASH registry: 2026-05-27
Structural basis of RGD-hirudin binding to thrombin: Tyr3 and five C-terminal residues are crucial for inhibiting thrombin activity
Huang Y et al. · BMC structural biology
Added to ASH registry: 2026-05-27
The complete mitochondrial genome of Paracymoriza distinctalis (Lepidoptera: Crambidae)
Ye F et al. · Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis
Added to ASH registry: 2026-05-27
The marginal mandibular nerve in relation to the inferior border of the mandible
Baur DA et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
Added to ASH registry: 2026-05-27
Trends in parenteral direct thrombin inhibitor use in pediatric patients: analysis of a large administrative database
Moffett BS et al. · Archives of pathology & laboratory medicine
Added to ASH registry: 2026-05-27
Hijamat in traditional Persian medicine: risks and benefits
Nimrouzi M et al. · Journal of evidence-based complementary & alternative medicine
Added to ASH registry: 2026-05-26
Alternative monitoring of argatroban using plasma-diluted thrombin time
Wanat et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-29
[Direct oral thrombin inhibitor, "dabigatran"].
Yasaka · Nihon rinsho. Japanese journal of clinical medicine
Added to ASH registry: 2026-05-28
A specific antidote for dabigatran: functional and structural characterization
Schiele et al. · Blood
Added to ASH registry: 2026-05-28
An update on recent patents on thrombin inhibitors (2010 - 2013)
Mehta AY et al. · Expert opinion on therapeutic patents
Added to ASH registry: 2026-05-28
Anticoagulant therapy with the oral direct factor Xa inhibitors rivaroxaban, apixaban and edoxaban and the thrombin inhibitor dabigatran etexilate in patients with hepatic impairment
Graff J et al. · Clinical pharmacokinetics
Added to ASH registry: 2026-05-28
Anticoagulation beyond direct thrombin and factor Xa inhibitors: indications for targeting the intrinsic pathway?
van Montfoort ML et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Anticoagulation for atrial fibrillation: state of the art and recommendations for a quickly moving target.
Nattel et al. · The Canadian journal of cardiology
Added to ASH registry: 2026-05-28
Antithrombotic activities of epi-sesamin in vitro and in vivo
Ku SK et al. · The American journal of Chinese medicine
Added to ASH registry: 2026-05-28
Apixaban and rivaroxaban decrease deep venous thrombosis but not other complications after total hip and total knee arthroplasty
Russell et al. · The Journal of arthroplasty
Added to ASH registry: 2026-05-28
Apixaban for extended treatment of venous thromboembolism
Agnelli et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Betrixaban compared with warfarin in patients with atrial fibrillation: results of a phase 2, randomized, dose-ranging study (Explore-Xa)
Connolly et al. · European heart journal
Added to ASH registry: 2026-05-28
Bifunctional lipocalin ameliorates murine immune complex-induced acute lung injury
Roversi et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Bivalirudin in acute coronary syndromes and percutaneous coronary intervention: should we use it?
Ten Y et al. · Heart, lung & circulation
Added to ASH registry: 2026-05-28
Blocking direct inhibitor bleeding
Millar et al. · Blood
Added to ASH registry: 2026-05-28
Central venous catheter care for the patient with cancer: American Society of Clinical Oncology clinical practice guideline.
Schiffer et al. · Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Added to ASH registry: 2026-05-28
Dabigatran and kidney disease: a bad combination
Knauf et al. · Clinical journal of the American Society of Nephrology : CJASN
Added to ASH registry: 2026-05-28
Dabigatran etexilate in atrial fibrillation
Vora · The Journal of the Association of Physicians of India
Added to ASH registry: 2026-05-28
Designing allosteric regulators of thrombin. Exosite 2 features multiple subsites that can be targeted by sulfated small molecules for inducing inhibition.
Sidhu PS et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis in vivo
Ma et al. · Blood
Added to ASH registry: 2026-05-28
Development and characterization of new peptidomimetic inhibitors of the West Nile virus NS2B-NS3 protease
Hammamy et al. · ChemMedChem
Added to ASH registry: 2026-05-28
Direct thrombin and factor Xa inhibition for stroke prevention in patients with atrial fibrillation
Galanis et al. · Hospital practice (1995)
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors and factor xa inhibitors can influence the diluted prothrombin time used as the initial screen for lupus anticoagulant
Olah et al. · Archives of pathology & laboratory medicine
Added to ASH registry: 2026-05-28
Disseminated intravascular coagulation.
Hossain et al. · Seminars in perinatology
Added to ASH registry: 2026-05-28
Ecarin modified rotational thrombelastometry: a point-of-care applicable alternative to monitor the direct thrombin inhibitor argatroban
Schaden et al. · Wiener klinische Wochenschrift
Added to ASH registry: 2026-05-28
Effects of natural and recombinant hirudin on VEGF expression and random skin flap survival in a venous congested rat model
Yingxin et al. · International surgery
Added to ASH registry: 2026-05-28
Factor Xa activation of factor V is of paramount importance in initiating the coagulation system: lessons from a tick salivary protein.
Schuijt et al. · Circulation
Added to ASH registry: 2026-05-28
Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition.
Roddick LA et al. · BMC biochemistry
Added to ASH registry: 2026-05-28
Heparin induced thrombocytopenia: review.
Dasararaju et al. · Expert review of hematology
Added to ASH registry: 2026-05-28
High-dose argatroban for heparin-induced thrombocytopenia in a child using a ventricular assist device
Pasala et al. · The Annals of thoracic surgery
Added to ASH registry: 2026-05-28
Implications of Dabigatran, a direct thrombin inhibitor, for oral surgery practice
Davis et al. · Journal (Canadian Dental Association)
Added to ASH registry: 2026-05-28
Management of cardiovascular disease in haemophilia.
Cayla et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Monitoring the direct thrombin inhibitors
Fritsma et al. · Clinical laboratory science : journal of the American Society for Medical Technology
Added to ASH registry: 2026-05-28
Moving toward a more ideal anticoagulant: the oral direct thrombin and factor Xa inhibitors
King CS et al. · Chest
Added to ASH registry: 2026-05-28
Neutron and X-ray crystallographic analysis of the human α-thrombin-bivalirudin complex at pD 5.0: protonation states and hydration structure of the enzyme-product complex.
Yamada et al. · Biochimica et biophysica acta
Added to ASH registry: 2026-05-28
Oral apixaban for the treatment of acute venous thromboembolism
Agnelli et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
P1 and P2' site mutations convert protease nexin-2 from a factor XIa inhibitor to a plasmin inhibitor
Navaneetham et al. · Journal of biochemistry
Added to ASH registry: 2026-05-28
Pharmacokinetics and pharmacodynamics of anticoagulants in paediatric patients
Yee et al. · Clinical pharmacokinetics
Added to ASH registry: 2026-05-28
Pharmacokinetics study of recombinant hirudin in the plasma of rats using chromogenic substrate, ELISA, and radioisotope assays
Jiang et al. · PloS one
Added to ASH registry: 2026-05-28
Protamine-induced immune thrombocytopenia.
Singla et al. · Transfusion
Added to ASH registry: 2026-05-28
Randomized, controlled trial of ultrasound-assisted catheter-directed thrombolysis for acute intermediate-risk pulmonary embolism.
Kucher N et al. · Circulation
Added to ASH registry: 2026-05-28
Recurring extracorporeal circuit clotting during continuous renal replacement therapy in fungal sepsis: successful treatment with argatroban.
Ferguson et al. · The American journal of the medical sciences
Added to ASH registry: 2026-05-28
Review article: heparin sensitivity and resistance: management during cardiopulmonary bypass.
Finley et al. · Anesthesia and analgesia
Added to ASH registry: 2026-05-28
Riociguat for the treatment of chronic thromboembolic pulmonary hypertension.
Ghofrani H et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Safety of bivalirudin in percutaneous coronary intervention following thrombolytic therapy
Sardi GL et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-28
Sodium citrate 4% versus heparin as a lock solution in hemodialysis patients with central venous catheters.
Yon et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme
Yoshimoto et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa
Al-Horani et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
The clinical and economic impact of bivalirudin for percutaneous coronary intervention
Malik N et al. · Expert review of pharmacoeconomics & outcomes research
Added to ASH registry: 2026-05-28
The clinical utility of bivalirudin in patients with coronary artery disease.
Garner et al. · Cardiovascular & hematological agents in medicinal chemistry
Added to ASH registry: 2026-05-28
The relationships among hemostatic markers, the withdrawal of fondaparinux due to a reduction in hemoglobin and deep vein thrombosis in Japanese patients undergoing major orthopedic surgery
Hasegawa et al. · Clinica chimica acta; international journal of clinical chemistry
Added to ASH registry: 2026-05-28
The serine protease domain of MASP-3: enzymatic properties and crystal structure in complex with ecotin
Gaboriaud et al. · PloS one
Added to ASH registry: 2026-05-28
Treatment of cancer-associated thrombosis.
Lee et al. · Blood
Added to ASH registry: 2026-05-28
Use of argatroban: experiences in continuous renal replacement therapy in critically ill patients after cardiac surgery.
Klingele et al. · The Journal of thoracic and cardiovascular surgery
Added to ASH registry: 2026-05-28
[Anticoagulation]
Ptzsch B · Medizinische Klinik, Intensivmedizin und Notfallmedizin
Added to ASH registry: 2026-05-27
Antithrombotic strategies in children receiving long-term Berlin Heart EXCOR ventricular assist device therapy
Rutledge JM et al. · Journal of heart and lung transplantation
Added to ASH registry: 2026-05-27
Bivalirudin in pediatric patients maintained on extracorporeal life support
Nagle EL et al. · Pediatric critical care medicine
Added to ASH registry: 2026-05-27
Characterization of currently marketed heparin products: key tests for LMWH quality assurance
Ye H et al. · Journal of pharmaceutical and biomedical analysis
Added to ASH registry: 2026-05-27
Comparison of antithrombotic and hemorrhagic effects of edoxaban, a novel factor Xa inhibitor, with unfractionated heparin, dalteparin, lepirudin and warfarin in rats
Morishima Y et al. · Thrombosis research
Added to ASH registry: 2026-05-27
Diversity and selective pressures of anticoagulants in three medicinal leeches (Hirudinida: Hirudinidae, Macrobdellidae)
Kvist S et al. · Ecol Evol
Added to ASH registry: 2026-05-27
Elevating local concentrations of GPIIb-IIIa antagonists counteracts platelet thrombus stability
Speich HE et al. · Journal of Thrombosis and Thrombolysis
Added to ASH registry: 2026-05-27
Evaluation of a multifunctional staphylokinase variant with thrombin inhibition and antiplatelet aggregation activities produced from salt-inducible E. coli GJ1158
Kumar A et al. · Canadian Journal of Physiology and Pharmacology
Added to ASH registry: 2026-05-27
Long-range electrostatic complementarity governs substrate recognition by human chymotrypsin C, a key regulator of digestive enzyme activation
Batra J et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-27
Method to detect contaminants in heparin using radical depolymerization and liquid chromatography-mass spectrometry
Li G et al. · Analytical chemistry
Added to ASH registry: 2026-05-27
New developments in parenteral anticoagulation for arterial and venous thromboembolism
van Es N et al. · Best Practice & Research Clinical Haematology
Added to ASH registry: 2026-05-27
Pharmacological adjuvant therapies in primary coronary interventions: bivalirudin
Lupi A et al. · Cardiovascular & hematological agents in medicinal chemistry
Added to ASH registry: 2026-05-27
The bivalirudin paradox: high evidence, low use
De Servi S et al. · Journal of cardiovascular medicine (Hagerstown, Md.)
Added to ASH registry: 2026-05-27
The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand
Boyle AJ et al. · BMC biochemistry
Added to ASH registry: 2026-05-27
The cruelty and failings of therapies for neurological diseases in French literature
Walusinski O et al. · Progress in brain research
Added to ASH registry: 2026-05-27
Thrombosis during off pump LVAD placement in a patient with heparin induced thrombocytopenia using bivalirudin
Awad H et al. · Journal of cardiothoracic surgery
Added to ASH registry: 2026-05-27
History of the leech trade in Ireland, 1750-1915: microcosm of a global commodity
Sawyer RT · Medical history
Added to ASH registry: 2026-05-26
Proton bridging in the interactions of thrombin with hirudin and its mimics
Kovach IM, Kakalis L, Jordan F, Zhang D · Biochemistry
Added to ASH registry: 2026-05-26
Leech therapeutic applications
Abdualkader A et al. · Indian journal of pharmaceutical sciences
Added to ASH registry: 2026-03-18
A case of unsuccessful treatment of heparin-induced thrombocytopenia (HIT) with fondaparinux
Miranda et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-29
Argatroban anticoagulation for heparin induced thrombocytopenia in patients with ventricular assist devices
Pappalardo et al. · Minerva anestesiologica
Added to ASH registry: 2026-05-29
Dabigatran use in a postoperative coronary artery bypass surgery patient with nonvalvular atrial fibrillation and heparin-PF4 antibodies
Fieland et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-29
Heparin-induced thrombocytopenia: in vitro studies on the interaction of dabigatran, rivaroxaban, and low-sulfated heparin, with platelet factor 4 and anti-PF4/heparin antibodies
Krauel et al. · Blood
Added to ASH registry: 2026-05-29
[Catheter-directed thrombolysis in iliofemoral deep-vein thrombosis].
Strijkers RHW et al. · Nederlands tijdschrift voor geneeskunde
Added to ASH registry: 2026-05-28
Anticoagulation for cerebral venous sinus thrombosis.
Coutinho et al. · Stroke
Added to ASH registry: 2026-05-28
Anticoagulation in pregnancy.
Goland et al. · Cardiology clinics
Added to ASH registry: 2026-05-28
Antiplatelet and antithrombin strategies in acute coronary syndrome: state-of-the-art review.
Showkathali R et al. · Current cardiology reviews
Added to ASH registry: 2026-05-28
Argatroban dose reductions for suspected heparin-induced thrombocytopenia complicated by child-pugh class C liver disease
Yarbrough et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Bivalirudin has its own shelf in the cath lab, eventually.
Cortese et al. · International journal of cardiology
Added to ASH registry: 2026-05-28
Bleeding risk factors associated with argatroban therapy in the critically ill
Doepker et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Cerebral sinus-venous thrombosis.
Martinelli et al. · Internal and emergency medicine
Added to ASH registry: 2026-05-28
Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism
Li et al. · Blood
Added to ASH registry: 2026-05-28
Crystallization and preliminary crystallographic characterization of the N-terminal Kunitz domain of boophilin
Cereija et al. · Acta crystallographica. Section F, Structural biology and crystallization communications
Added to ASH registry: 2026-05-28
Dabigatran etexilate: a pharmacoeconomic review of its use in the prevention of stroke and systemic embolism in patients with atrial fibrillation
McKeage · PharmacoEconomics
Added to ASH registry: 2026-05-28
Dabigatran etexilate: a review of its use for the prevention of venous thromboembolism after total hip or knee replacement surgery
Burness et al. · Drugs
Added to ASH registry: 2026-05-28
Dabigatran etexilate: an oral direct thrombin inhibitor for the management of thromboembolic disorders
Cheng et al. · Clinical therapeutics
Added to ASH registry: 2026-05-28
Dabigatran etexilate: what do hospitalists need to know?
Zeidan et al. · Journal of hospital medicine
Added to ASH registry: 2026-05-28
Dabigatran or warfarin for the prevention of stroke in atrial fibrillation? A closer look at the RE-LY trial.
DiNicolantonio · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-28
Determination of dabigatran in human plasma samples
Harenberg et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Direct thrombin inhibitor (DTI) vs. aspirin in primary total hip and knee replacement using wound ooze as the primary outcome measure. A prospective cohort study
Aquilina et al. · Hip international : the journal of clinical and experimental research on hip pathology and therapy
Added to ASH registry: 2026-05-28
Direct thrombin inhibitor-bivalirudin functionalized plasma polymerized allylamine coating for improved biocompatibility of vascular devices
Yang et al. · Biomaterials
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors for management of heparin-induced thrombocytopenia in patients receiving renal replacement therapy: comparison of clinical outcomes.
Abel et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors in cardiovascular disease
Arsenault et al. · Nature reviews. Cardiology
Added to ASH registry: 2026-05-28
Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor
Dockendorff C et al. · ACS medicinal chemistry letters
Added to ASH registry: 2026-05-28
Discovery of benzothiazole guanidines as novel inhibitors of thrombin and trypsin IV
Karle et al. · Bioorganic & medicinal chemistry letters
Added to ASH registry: 2026-05-28
Duration of anticoagulation after cerebral venous sinus thrombosis.
Caprio et al. · Neurocritical care
Added to ASH registry: 2026-05-28
Exploration of the antiplatelet activity profile of betulinic acid on human platelets
Tzakos AG et al. · Journal of agricultural and food chemistry
Added to ASH registry: 2026-05-28
Functional characterisation of vizottin, the first factor Xa inhibitor purified from the leech Haementeria vizottoi
Oliveira et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
High-resolution crystal structure of human protease-activated receptor 1
Zhang et al. · Nature
Added to ASH registry: 2026-05-28
Identification of 3'UTR sequence elements and a teloplasm localization motif sufficient for the localization of Hro-twist mRNA to the zygotic animal and vegetal poles.
Farooq M et al. · Development, growth & differentiation
Added to ASH registry: 2026-05-28
Management consensus guidance for the use of rivaroxaban--an oral, direct factor Xa inhibitor
Turpie AG et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Management of bleeding in patients receiving conventional or new anticoagulants: a practical and case-based approach.
Donadini et al. · Drugs
Added to ASH registry: 2026-05-28
Measuring direct thrombin inhibitors with routine and dedicated coagulation assays: which assay is helpful?
Curvers et al. · American journal of clinical pathology
Added to ASH registry: 2026-05-28
Meta-analysis comparing bivalirudin versus heparin monotherapy on ischemic and bleeding outcomes after percutaneous coronary intervention.
Bertrand et al. · The American journal of cardiology
Added to ASH registry: 2026-05-28
Meta-analysis of safety and efficacy of uninterrupted warfarin compared to heparin-based bridging therapy during implantation of cardiac rhythm devices.
Ghanbari H et al. · The American journal of cardiology
Added to ASH registry: 2026-05-28
Moderate pulmonary embolism treated with thrombolysis (from the "MOPETT" Trial).
Sharifi M et al. · The American journal of cardiology
Added to ASH registry: 2026-05-28
Modification of polyurethane with polyethylene glycol-corn trypsin inhibitor for inhibition of factor Xlla in blood contact
Alibeik et al. · Journal of biomaterials science. Polymer edition
Added to ASH registry: 2026-05-28
New oral antithrombotics: focus on dabigatran, an oral, reversible direct thrombin inhibitor for the prevention and treatment of venous and arterial thromboembolic disorders
Dahl et al. · Vascular health and risk management
Added to ASH registry: 2026-05-28
New targets for anticoagulation and future perspectives
Ansell J et al. · Current drug discovery technologies
Added to ASH registry: 2026-05-28
Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Ageno W et al. · Chest
Added to ASH registry: 2026-05-28
Outcomes after heparin-induced thrombocytopenia in patients with Propaten vascular grafts
Kasirajan · Annals of vascular surgery
Added to ASH registry: 2026-05-28
Peri-procedural bridging with low molecular weight heparin in patients receiving warfarin for venous thromboembolism: a pediatric experience.
Moruf A et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Douketis et al. · Chest
Added to ASH registry: 2026-05-28
Pharmacokinetic evaluation of argatroban for the treatment of acute coronary syndrome
CruzGonzlez et al. · Expert opinion on drug metabolism & toxicology
Added to ASH registry: 2026-05-28
Pharmacokinetics and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor, with coadministration of digoxin
Stangier et al. · Journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Pharmacophore fingerprint-based approach to binding site subpocket similarity and its application to bioisostere replacement
Wood et al. · Journal of chemical information and modeling
Added to ASH registry: 2026-05-28
Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold.
Al-Horani RA et al. · European journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Practical use of apixaban in the prevention of venous thromboembolism after total knee or hip replacement
Lassen · Drugs of today (Barcelona, Spain : 1998)
Added to ASH registry: 2026-05-28
Protein C anticoagulant and cytoprotective pathways.
Griffin et al. · International journal of hematology
Added to ASH registry: 2026-05-28
Pulmonary embolism and deep vein thrombosis.
Goldhaber et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors
Figueiredo AC et al. · PloS one
Added to ASH registry: 2026-05-28
Recognition of heparin-induced thrombocytopenia and initiation of argatroban therapy after cardiothoracic surgery in the intensive care unit
Demma et al. · The Journal of thoracic and cardiovascular surgery
Added to ASH registry: 2026-05-28
Results of a consensus meeting on the use of argatroban in patients with heparin-induced thrombocytopenia requiring antithrombotic therapy - a European Perspective
Alatri et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Rivaroxaban in atrial fibrillation.
Giorgi et al. · Vascular health and risk management
Added to ASH registry: 2026-05-28
Safety and effectiveness outcomes of an inpatient collaborative drug therapy management service for direct thrombin inhibitors
Cooper et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Segmental and regional differences in neuronal expression of the leech Hox genes Lox1 and Lox2 during embryogenesis.
Gharbaran et al. · Cellular and molecular neurobiology
Added to ASH registry: 2026-05-28
Selective factor XIIa inhibition attenuates silent brain ischemia: application of molecular imaging targeting coagulation pathway
Chen et al. · JACC. Cardiovascular imaging
Added to ASH registry: 2026-05-28
Structural biology of factor VIIa/tissue factor initiated coagulation.
Vadivel et al. · Frontiers in bioscience (Landmark edition)
Added to ASH registry: 2026-05-28
The identification and management of heparin-induced thrombocytopenia in the vascular patient
LaMuraglia et al. · Journal of vascular surgery
Added to ASH registry: 2026-05-28
Thrombin activity associated with neuronal damage during acute focal ischemia
Chen et al. · The Journal of neuroscience : the official journal of the Society for Neuroscience
Added to ASH registry: 2026-05-28
Thromboembolic prophylaxis in orthopedic surgery using dabigatran: an oral direct thrombin inhibitor
Garza et al. · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-28
Agarose-gel electrophoresis for the quality assurance and purity of heparin formulations
Volpi N et al. · Journal of pharmaceutical and biomedical analysis
Added to ASH registry: 2026-05-27
Biotechnological production of recombinant analogs of hirudin-1 from Hirudo medicinalis
Kostromina MA et al. · Bioorganicheskaia khimiia
Added to ASH registry: 2026-05-27
Bivalirudin for primary percutaneous coronary intervention in acute myocardial infarction: the HORIZONS-AMI trial
Capranzano P et al. · Expert Rev Cardiovasc Ther
Added to ASH registry: 2026-05-27
Bivalirudin for primary percutaneous coronary interventions: outcome assessment in the Ottawa STEMI registry
Hibbert B et al. · Circulation Cardiovascular Interventions
Added to ASH registry: 2026-05-27
Designing allosteric regulators of thrombin. Monosulfated benzofuran dimers selectively interact with Arg173 of exosite 2 to induce inhibition
Abdel Aziz MH et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-27
Disintegrins from hematophagous sources
Assumpcao TC et al. · Toxins (Basel)
Added to ASH registry: 2026-05-27
Disintegrins from hematophagous sources
Assumpcao TCF et al. · Toxins
Added to ASH registry: 2026-05-27
Disintegrins from hematophagous sources
Assumpcao TC et al. · Toxins
Added to ASH registry: 2026-05-27
Electrophoresis for the analysis of heparin purity and quality
Volpi N et al. · Electrophoresis
Added to ASH registry: 2026-05-27
Emerging anticoagulants
Kennedy B et al. · Current Medicinal Chemistry
Added to ASH registry: 2026-05-27
Evaluation of dose requirements for prolonged bivalirudin administration in patients with renal insufficiency and suspected heparin-induced thrombocytopenia
Wisler JW et al. · Journal of Thrombosis and Thrombolysis
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia in the pediatric population: a review of current literature
Vakil NH et al. · The journal of pediatric pharmacology and therapeutics
Added to ASH registry: 2026-05-27
Identification of a novel structure in heparin generated by sequential oxidative-reductive treatment
Beccati D et al. · Analytical chemistry
Added to ASH registry: 2026-05-27
Impact of stage 3B chronic kidney disease on thrombosis and bleeding outcomes after orthopedic surgery in patients treated with desirudin or enoxaparin: insights from a randomized trial
Shorr AF et al. · Journal of thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Interactions of oversulfated chondroitin sulfate (OSCS) from different sources with unfractionated heparin
Gray A et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-27
Interference of thrombin in immunological assays for hirudin specific antibodies
Hamilton RG et al. · Journal of immunological methods
Added to ASH registry: 2026-05-27
Intra-procedural stent thrombosis: a new risk factor for adverse outcomes in patients undergoing percutaneous coronary intervention for acute coronary syndromes
Brener SJ et al. · JACC Cardiovasc Interv
Added to ASH registry: 2026-05-27
Investigation on the microcirculation effect of local application of natural hirudin on porcine random skin flap venous congestion
Yin GQ et al. · Cell biochemistry and biophysics
Added to ASH registry: 2026-05-27
Multicenter trial of desirudin for the prophylaxis of thrombosis: an alternative to heparin-based anticoagulation (DESIR-ABLE)
Bergese SD et al. · Clin Appl Thromb Hemost
Added to ASH registry: 2026-05-27
Otorrhagia bleeding due to leech bite
Askari N et al. · Advanced biomedical research
Added to ASH registry: 2026-05-27
Outcome of the HORIZONS-AMI trial: bivalirudin enhances long-term survival in patients with ST-elevation myocardial infarction undergoing angioplasty
Shah A et al. · Vasc Health Risk Manag
Added to ASH registry: 2026-05-27
Outcomes of patients with prior coronary artery bypass grafting and acute coronary syndromes: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial
Nikolsky E et al. · JACC. Cardiovascular interventions
Added to ASH registry: 2026-05-27
Prognostic significance of elevated baseline troponin in patients with acute coronary syndromes and chronic kidney disease treated with different antithrombotic regimens: a substudy from the ACUITY trial
Acharji S et al. · Circulation. Cardiovascular interventions
Added to ASH registry: 2026-05-27
The therapeutic management of bleeding and thrombotic disorders complicating CNS malignancies
Strowd RE et al. · Current treatment options in oncology
Added to ASH registry: 2026-05-27
The Use of Bivalirudin in ST-Segment Elevation Myocardial Infarction: Advantages and Limitations
Sergie Z et al. · Interv Cardiol Clin
Added to ASH registry: 2026-05-27
Translational success stories: development of direct thrombin inhibitors
Coppens M et al. · Circulation research
Added to ASH registry: 2026-05-27
New anticoagulants - direct thrombin inhibitors
Brand B, Graf L · Therapeutische Umschau
Added to ASH registry: 2026-05-26
Parenteral anticoagulants: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Garcia DA, Baglin TP, Weitz JI, Samama MM · Chest
Added to ASH registry: 2026-05-26
Heparin-induced thrombocytopenia: successful biological and clinical management with lepirudin despite severe renal impairment
Desconclois et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-29
Successful use of hirudin during cardiac surgery using minimized extracorporeal circulation in patients with heparin-induced thrombocytopenia
Haneya et al. · The Annals of thoracic surgery
Added to ASH registry: 2026-05-29
A common standard is inappropriate for determining the potency of ultra low molecular weight heparins such as semuloparin and bemiparin
Jeske WP et al. · Thrombosis research
Added to ASH registry: 2026-05-28
A randomized, open-label pilot study comparing desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without thrombosis: PREVENT-HIT Study
Boyce et al. · American journal of therapeutics
Added to ASH registry: 2026-05-28
Advances in anticoagulation: focus on dabigatran, an oral direct thrombin inhibitor
Augoustides JG · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-28
Anticoagulant, anti-aggregation and antithrombotic effects of a novel hexapeptide
Long LH et al. · The Journal of pharmacy and pharmacology
Added to ASH registry: 2026-05-28
Anticoagulation for cerebral venous sinus thrombosis.
Coutinho et al. · The Cochrane database of systematic reviews
Added to ASH registry: 2026-05-28
Anticoagulation with argatroban for elective percutaneous coronary intervention: population pharmacokinetics and pharmacokinetic-pharmacodynamic relationship of coagulation parameters
Akimoto et al. · Journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Antiinflammatory and antifibrotic effects of the oral direct thrombin inhibitor dabigatran etexilate in a murine model of interstitial lung disease
Bogatkevich et al. · Arthritis and rheumatism
Added to ASH registry: 2026-05-28
Antithrombin-independent thrombin inhibitors, but not direct factor Xa inhibitors, enhance thrombin generation in plasma through inhibition of thrombin-thrombomodulin-protein C system
Furugohri et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Apixaban for stroke prevention in atrial fibrillation: a review of the clinical trial evidence.
Yates · Hospital practice (1995)
Added to ASH registry: 2026-05-28
Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I.
Zarpellon A et al. · Proceedings of the National Academy of Sciences of the United States of America
Added to ASH registry: 2026-05-28
Bivalirudin is a dual inhibitor of thrombin and collagen-dependent platelet activation in patients undergoing percutaneous coronary intervention.
Kimmelstiel et al. · Circulation. Cardiovascular interventions
Added to ASH registry: 2026-05-28
Bivalirudin utilization in cardiac surgery: shifting anticoagulation from indirect to direct thrombin inhibition
Anand et al. · Canadian journal of anaesthesia = Journal canadien d'anesthesie
Added to ASH registry: 2026-05-28
Bivalirudin: a pharmacoeconomic profile of its use in patients with acute coronary syndromes
Lyseng-Williamson et al. · PharmacoEconomics
Added to ASH registry: 2026-05-28
Conformationally restricted analogs of the direct thrombin inhibitor FM 19
Girnys et al. · Bioorganic & medicinal chemistry
Added to ASH registry: 2026-05-28
Dabigatran etexilate in clinical practice: confronting challenges to improve safety and effectiveness
Gulseth et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Dabigatran etexilate versus warfarin as the oral anticoagulant of choice? A review of clinical data
Ma et al. · Pharmacology & therapeutics
Added to ASH registry: 2026-05-28
Dabigatran etexilate: a new oral anticoagulant
Hayes · South Dakota medicine : the journal of the South Dakota State Medical Association
Added to ASH registry: 2026-05-28
Dabigatran etexilate: a new oral thrombin inhibitor
Hankey et al. · Circulation
Added to ASH registry: 2026-05-28
Dabigatran etexilate: A novel oral direct thrombin inhibitor
Blommel ML et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Dabigatran etexilate: a novel oral thrombin inhibitor for thromboembolic disease
Bovio et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Dabigatran etexilate: a possible replacement for heparinoids and vitamin K antagonists?
Guay · Hospital practice (1995)
Added to ASH registry: 2026-05-28
Dabigatran etexilate: the first oral anticoagulant available in the United States since warfarin
Tran et al. · Cardiology in review
Added to ASH registry: 2026-05-28
Dabigatran: a review of clinical and pharmacoeconomic evidence
Reddy et al. · Critical pathways in cardiology
Added to ASH registry: 2026-05-28
Dabigatran: an oral direct thrombin inhibitor for use in atrial fibrillation
Bendel et al. · Advances in therapy
Added to ASH registry: 2026-05-28
Desirudin: a review of the pharmacology and clinical application for the prevention of deep vein thrombosis
Graetz et al. · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-28
Edoxaban: a new oral direct factor xa inhibitor
Camm et al. · Drugs
Added to ASH registry: 2026-05-28
Effects of argatroban as an anticoagulant for intermittent veno-venous hemofiltration (IVVH) in patients at high risk of bleeding
Sun et al. · Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Added to ASH registry: 2026-05-28
Effects of the oral, direct thrombin inhibitor dabigatran on five common coagulation assays
Lindahl et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Energetics of hydrogen bond switch, residue burial and cavity analysis reveals molecular basis of improved heparin binding to antithrombin
Singh et al. · Journal of biomolecular structure & dynamics
Added to ASH registry: 2026-05-28
Epidemiology and incidence: the scope of the problem and risk factors for development of venous thromboembolism.
Stein et al. · Critical care clinics
Added to ASH registry: 2026-05-28
Evaluation of empiric versus nomogram-based direct thrombin inhibitor management in patients with suspected heparin-induced thrombocytopenia
Kiser et al. · American journal of hematology
Added to ASH registry: 2026-05-28
Guidelines for the treatment of acute ischaemic stroke.
Alonso de Leciñana et al. · Neurologia (Barcelona, Spain)
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia and extracorporeal membrane oxygenation: a case report and review of the literature
Pollak et al. · The journal of extra-corporeal technology
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia: comparison between response to fondaparinux and lepirudin
Al-Rossaies et al. · International journal of clinical pharmacy
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia.
Shaikh · Journal of emergencies, trauma, and shock
Added to ASH registry: 2026-05-28
Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1
Dowal L et al. · Proceedings of the National Academy of Sciences of the United States of America
Added to ASH registry: 2026-05-28
Long-term outcome after additional catheter-directed thrombolysis versus standard treatment for acute iliofemoral deep vein thrombosis (the CaVenT study): a randomised controlled trial.
Enden T et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
Looking back into the future: desirudin in acute coronary syndromes and coronary stenting
Vranckx et al. · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Added to ASH registry: 2026-05-28
Mechanism of catheter thrombosis: comparison of the antithrombotic activities of fondaparinux, enoxaparin, and heparin in vitro and in vivo
Yau et al. · Blood
Added to ASH registry: 2026-05-28
New oral anticoagulant drugs: dabigatran, rivaroxaban and apixaban. Present and future
Dumont B et al. · Medecine sciences : M/S
Added to ASH registry: 2026-05-28
New parenteral anticoagulants in development
Gómez-Outes A et al. · Therapeutic advances in cardiovascular disease
Added to ASH registry: 2026-05-28
On the dosing of lepirudin
Alberio et al. · British journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Pediatric catheterization laboratory anticoagulation with bivalirudin.
Forbes et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-28
Pharmacokinetic and pharmacodynamic basis for effective argatroban dosing in pediatrics
Madabushi et al. · Journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Relipidated tissue factor linked to collagen surfaces potentiates platelet adhesion and fibrin formation in a microfluidic model of vessel injury
Colace et al. · Bioconjugate chemistry
Added to ASH registry: 2026-05-28
S35972, a direct-acting thrombin inhibitor with high oral bioavailability and antithrombotic efficacy
Rupin A et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction.
Corral-Rodríguez M& et al. · Blood
Added to ASH registry: 2026-05-28
Sulfated, low molecular weight lignins inhibit a select group of heparin-binding serine proteases.
Henry BL et al. · Biochemical and biophysical research communications
Added to ASH registry: 2026-05-28
The discovery and development of rivaroxaban, an oral, direct factor Xa inhibitor
Perzborn et al. · Nature reviews. Drug discovery
Added to ASH registry: 2026-05-28
The mechanism of action of rivaroxaban--an oral, direct Factor Xa inhibitor--compared with other anticoagulants
Samama et al. · Thrombosis research
Added to ASH registry: 2026-05-28
The practical management of intracerebral hemorrhage associated with oral anticoagulant therapy.
Masotti et al. · International journal of stroke : official journal of the International Stroke Society
Added to ASH registry: 2026-05-28
The protein C pathway and sepsis.
Della Valle et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Therapeutic potential of apixaban in the prevention of venous thromboembolism in patients undergoing total knee replacement surgery
Martin et al. · Current medical research and opinion
Added to ASH registry: 2026-05-28
Thrombin inhibitor or factor xa inhibitor? -Opening of a New Era of antithrombotic management-
Atarashi et al. · Circulation journal : official journal of the Japanese Circulation Society
Added to ASH registry: 2026-05-28
Tissue factor/TFPI and blood cells.
Osterud · Thrombosis research
Added to ASH registry: 2026-05-28
Use of prolonged bivalirudin infusions following percutaneous coronary intervention
Moser LR et al. · Cardiovascular drugs and therapy
Added to ASH registry: 2026-05-28
von Willebrand disease.
James PD et al. · Genetics in medicine : official journal of the American College of Medical Genetics
Added to ASH registry: 2026-05-28
A systematic overview of the medicinal importance of sanguivorous leeches
Zaidi SM et al. · Alternative medicine review
Added to ASH registry: 2026-05-27
An optimized method to assess in vivo efficacy of antithrombotic drugs using optical coherence tomography and a modified Doppler flow system
Couture L et al. · Journal of pharmacological and toxicological methods
Added to ASH registry: 2026-05-27
Bivalirudin use in an infant with persistent clotting on unfractionated heparin
Malloy KM et al. · Journal of Pediatric Pharmacology and Therapeutics
Added to ASH registry: 2026-05-27
Bivalirudin-based versus conventional heparin anticoagulation for postcardiotomy extracorporeal membrane oxygenation
Ranucci M et al. · Critical care
Added to ASH registry: 2026-05-27
Crystal structure of thrombin in complex with S-variegin: insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors
Koh CY et al. · PloS one
Added to ASH registry: 2026-05-27
Effect of O-glycosylation and tyrosine sulfation of leech-derived peptides on binding and inhibitory activity against thrombin
Hsieh YS et al. · Chemical communications
Added to ASH registry: 2026-05-27
Effect of O-glycosylation and tyrosine sulfation of leech-derived peptides on binding and inhibitory activity against thrombin
Hsieh YS et al. · Chemical communications
Added to ASH registry: 2026-05-27
Evaluation of a standardized protocol using lepirudin or argatroban for heparin-induced thrombocytopenia
Kennedy K et al. · Cardiovascular & Hematological Agents in Medicinal Chemistry
Added to ASH registry: 2026-05-27
Genomic insights into an obligate epibiotic bacterial predator: Micavibrio aeruginosavorus ARL-13
Wang Z et al. · BMC genomics
Added to ASH registry: 2026-05-27
How serious a problem is bleeding in patients with acute coronary syndromes?
Baber U et al. · Current cardiology reports
Added to ASH registry: 2026-05-27
New derivative of staphylokinase SAK-RGD-K2-Hirul exerts thrombolytic effects in the arterial thrombosis model in rats
Szemraj J et al. · Pharmacological reports : PR
Added to ASH registry: 2026-05-27
Prognostic value of the SYNTAX score in patients with acute coronary syndromes undergoing percutaneous coronary intervention: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage StrategY) trial
Palmerini T et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-27
Re-imagining bleeders: the medical leech in the nineteenth century bloodletting encounter
Kirk RGW et al. · Medical history
Added to ASH registry: 2026-05-27
Redesigning allosteric activation in an enzyme
Rana S et al. · Proceedings of the National Academy of Sciences of the United States of America
Added to ASH registry: 2026-05-27
Sensitive detection of oversulfated chondroitin sulfate in heparin sodium or crude heparin with a colorimetric microplate based assay
Sommers CD et al. · Analytical chemistry
Added to ASH registry: 2026-05-27
The occurrence of antibodies to heparin-platelet factor 4 in cardiac and thoracic surgical patients receiving desirudin or heparin for postoperative venous thrombosis prophylaxis
Avidan MS et al. · Thrombosis Research
Added to ASH registry: 2026-05-27
Two hour bivalirudin infusion after PCI for ST elevation myocardial infarction
Anderson PR et al. · Journal of Thrombosis and Thrombolysis
Added to ASH registry: 2026-05-27
Update in hematology: heparin-induced thrombocytopenia and bivalirudin
Augoustides JGT · Journal of Cardiothoracic and Vascular Anesthesia
Added to ASH registry: 2026-05-27
Direct thrombin inhibitors
Lee CJ, Ansell JE · British journal of clinical pharmacology
Added to ASH registry: 2026-05-26
Chemical and mechanical alternatives to leech therapy: a systematic review and critical appraisal
Azzopardi E et al. · Journal of reconstructive microsurgery
Added to ASH registry: 2026-03-18
Leech therapy- a holistic approach of treatment in unani (greeko-arab) medicine
Lone A et al. · Ancient science of life
Added to ASH registry: 2026-03-18
Alteration of pharmacokinetics of lepirudin caused by anti-lepirudin antibodies occurring after long-term subcutaneous treatment in a patient with recurrent VTE due to Behcets disease
Linnemann et al. · VASA. Zeitschrift fur Gefasskrankheiten
Added to ASH registry: 2026-05-29
Fondaparinux for the treatment of acute heparin-induced thrombocytopenia: a single-center experience
Grouzi et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-29
Heparin-induced thrombocytopenia in a patient treated with fondaparinux
Ratuapli et al. · Clinical advances in hematology & oncology : H&O
Added to ASH registry: 2026-05-29
Apixaban, a direct factor Xa inhibitor, inhibits tissue-factor induced human platelet aggregation in vitro: comparison with direct inhibitors of factor VIIa, XIa and thrombin
Wong PC et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Argatroban as a substitute of heparin during cardiopulmonary bypass: a safe alternative?
Follis et al. · Interactive cardiovascular and thoracic surgery
Added to ASH registry: 2026-05-28
Argatroban in the management of heparin-induced thrombocytopenia
Babuin et al. · Vascular health and risk management
Added to ASH registry: 2026-05-28
Atorvastatin has antithrombotic effects in patients with type 1 diabetes and dyslipidemia
Tehrani S et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Bivalirudin: a review of the pharmacology and clinical application
Van et al. · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-28
Bivalirudin: alternative anticoagulation during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia
Grubb et al. · Recent patents on cardiovascular drug discovery
Added to ASH registry: 2026-05-28
Boehringer launches first direct thrombin inhibitor: dabigatran (Pradaxa)
Anonymous · Cardiovascular journal of Africa
Added to ASH registry: 2026-05-28
Comparison of bivalirudin and argatroban for the management of heparin-induced thrombocytopenia
Skrupky et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Comparison of monitoring methods for lepirudin: impact of warfarin and lupus anticoagulant
Salmela et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Dabigatran etexilate
Dubois et al. · British journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Dabigatran etexilate--a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity
van Ryn J et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Dabigatran etexilate, a new oral direct thrombin inhibitor, for stroke prevention in patients with atrial fibrillation
Siddiqui FM et al. · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-28
Dabigatran etexilate: a new thrombin inhibitor
Verma · The Medical journal of Australia
Added to ASH registry: 2026-05-28
Dabigatran: an oral novel potent reversible nonpeptide inhibitor of thrombin
Eisert et al. · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-28
Desirudin dosing and monitoring in moderate renal impairment
Nafziger et al. · Journal of clinical pharmacology
Added to ASH registry: 2026-05-28
Detection of endogenous tissue factor levels in plasma using the calibrated automated thrombogram assay
Ollivier et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Epidemiology and incidence: the scope of the problem and risk factors for development of venous thromboembolism.
Stein et al. · Clinics in chest medicine
Added to ASH registry: 2026-05-28
Factor XIIa inhibitor recombinant human albumin Infestin-4 abolishes occlusive arterial thrombus formation without affecting bleeding
Hagedorn et al. · Circulation
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia: evaluation of IgG and IgGAM ELISA assays.
Morel-Kopp et al. · International journal of laboratory hematology
Added to ASH registry: 2026-05-28
Incidence and time course of asymptomatic deep vein thrombosis with fondaparinux in patients undergoing total joint arthroplasty
Yamaguchi et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Inhibition of factor XIa as a new approach to anticoagulation
Schumacher et al. · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-28
Ligand binding shuttles thrombin along a continuum of zymogen- and proteinase-like states.
Kamath P et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
New options with dabigatran etexilate in anticoagulant therapy
Maegdefessel et al. · Vascular health and risk management
Added to ASH registry: 2026-05-28
Oral rivaroxaban for symptomatic venous thromboembolism
EINSTEIN et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Pulmonary embolism.
McRae · Australian family physician
Added to ASH registry: 2026-05-28
Recombinant factor VIIa to manage major bleeding from newer parenteral anticoagulants
Vavra KA et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Review: recent advances in argatroban-warfarin transition in patients with heparin-induced thrombocytopenia
Taimeh et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Rivaroxaban vs dabigatran for thromboprophylaxis after joint-replacement surgery: exploratory indirect comparison based on meta-analysis of pivotal clinical trials
Trkulja et al. · Croatian medical journal
Added to ASH registry: 2026-05-28
Structure-based design of residue 1 analogs of the direct thrombin inhibitor pentapeptide FM 19
Girnys EA et al. · Chemical biology & drug design
Added to ASH registry: 2026-05-28
The antithrombotic effect of a novel hirudin derivative after reconstruction of carotid artery in rabbits.
Lu WF et al. · Thrombosis research
Added to ASH registry: 2026-05-28
The direct thrombin inhibitor argatroban effectively prevents cardiac catheter thrombosis in vitro
Raaz U et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
The paradoxical stimulation by a reversible thrombin inhibitor of thrombin generation in plasma measured with thrombinography is caused by alpha-macroglobulin-thrombin
Wagenvoord et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
YM-150, a Factor Xa inhibitor for the prevention of venous thromboembolism and coronary artery disease
Markel et al. · Current opinion in investigational drugs (London, England : 2000)
Added to ASH registry: 2026-05-28
A risk score to predict bleeding in patients with acute coronary syndromes
Mehran R et al. · J Am Coll Cardiol
Added to ASH registry: 2026-05-27
Argatroban therapy in pediatric patients requiring nonheparin anticoagulation: an open-label, safety, efficacy, and pharmacokinetic study
Young G et al. · Pediatric Blood & Cancer
Added to ASH registry: 2026-05-27
Bivalirudin use during radiofrequency catheter ablation procedures in two patients with a history of heparin-induced thrombocytopenia
Baetz BE et al. · Pharmacotherapy
Added to ASH registry: 2026-05-27
Bivalirudin versus unfractionated heparin for prevention of hemofilter occlusion during continuous renal replacement therapy
Kiser TH et al. · Pharmacotherapy
Added to ASH registry: 2026-05-27
Destabilase-lysozyme of medicinal leech. Multifunctionality of recombinant protein
Zavalova LL et al. · Biochemistry (Mosc)
Added to ASH registry: 2026-05-27
Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of venous thromboembolism following total hip or knee replacement
Salazar CA et al. · Cochrane Database Syst Rev
Added to ASH registry: 2026-05-27
Emerging anticoagulants for venous thromboembolism prevention
Trujillo TC · Am J Health Syst Pharm
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia and cardiac surgery
Levy JH, Winkler AM · Current opinion in anaesthesiology
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia: a practical review
Hong MS, Amanullah AM · Reviews in Cardiovascular Medicine
Added to ASH registry: 2026-05-27
National survey of the use and application of leeches in oral and maxillofacial surgery in the United Kingdom
Taneja P et al. · British journal of oral & maxillofacial surgery
Added to ASH registry: 2026-05-27
Paradoxical interactions between modifiers and elastase-2
Schenker P et al. · The FEBS journal
Added to ASH registry: 2026-05-27
Rationale and design of the PREVENT-HIT study: a randomized, open-label pilot study to compare desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia
Frame JN et al. · Clinical therapeutics
Added to ASH registry: 2026-05-27
The leech: a novel invertebrate model for studying muscle regeneration and diseases
Grimaldi A et al. · Current pharmaceutical design
Added to ASH registry: 2026-05-26
Leech-derived thrombin inhibitors: from structures to mechanisms to clinical applications
Corral-Rodríguez M et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-03-18
Medicinal leech therapy (hirudotherapy): a brief overview
Singh A · Complementary therapies in clinical practice
Added to ASH registry: 2026-03-18
Surface modification with PEG and hirudin for protein resistance and thrombin neutralization in blood contact
Alibeik S, Zhu S, Brash J · Colloids and surfaces. B, Biointerfaces
Added to ASH registry: 2026-03-18
A comparison of direct thrombin inhibitors in the treatment of Heparin-Induced Thrombocytopenia: a single institution experience
Curzio et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-29
Implementation of a collaborative drug therapy management service for inpatients receiving direct thrombin inhibitors
Cooper et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-29
Lepirudin treatment in a boy with suspected HIT II after surgery because of tetralogy of Fallot
Hanke et al. · Hamostaseologie
Added to ASH registry: 2026-05-29
Lepirudin treatment in a girl with iliac vein thrombosis, severe pulmonary embolism and suspected heparin-induced thrombocytopenia (HIT) II
Walter et al. · Klinische Padiatrie
Added to ASH registry: 2026-05-29
Thrombin-inducible platelet adhesion and regulation of the platelet seven-transmembrane thrombin receptor-1 (PAR-1): effects of unfractionated heparin and lepirudin
Reiter et al. · Platelets
Added to ASH registry: 2026-05-29
Aeruginosin analogs and other compounds with rigid bicyclic structure as potential antithrombotic agents
Wang G et al. · Cardiovascular & hematological agents in medicinal chemistry
Added to ASH registry: 2026-05-28
Anticoagulant activity of a sulfated galactan: serpin-independent effect and specific interaction with factor Xa.
Glauser et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Anticoagulation for continuous renal replacement therapy.
Tolwani et al. · Seminars in dialysis
Added to ASH registry: 2026-05-28
Anticoagulation with the direct thrombin inhibitor argatroban in patients presenting with acute coronary syndromes
Yeh RW et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-28
Argatroban for anticoagulation in continuous renal replacement therapy.
Link et al. · Critical care medicine
Added to ASH registry: 2026-05-28
Argatroban for anticoagulation in continuous renal replacement therapy.
Keegan et al. · Critical care medicine
Added to ASH registry: 2026-05-28
Argatroban: a review of its use in the management of heparin-induced thrombocytopenia.
Dhillon · American journal of cardiovascular drugs : drugs, devices, and other interventions
Added to ASH registry: 2026-05-28
Biochemical and pharmacological effects of the direct thrombin inhibitor AR-H067637
Deinum J et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Bivalirudin as compared to unfractionated heparin among patients undergoing coronary angioplasty: A meta-analyis of randomised trials
De et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Characterization of an i-type lysozyme gene from the sea cucumber Stichopus japonicus, and enzymatic and nonenzymatic antimicrobial activities of its recombinant protein.
Cong L et al. · Journal of bioscience and bioengineering
Added to ASH registry: 2026-05-28
Dabigatran etexilate for the prophylaxis of venous thromboembolism after hip or knee replacement rationale for dose regimen
Dahl · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Dabigatran etexilate in venous thromboembolism
Ferrer · Drugs of today (Barcelona, Spain : 1998)
Added to ASH registry: 2026-05-28
Dabigatran etexilate: future directions in anticoagulant treatment
Schulman et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Dabigatran etexilate: pivotal trials for venous thromboembolism prophylaxis after hip or knee arthroplasty
Eriksson et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Dabigatran, a direct thrombin inhibitor, demonstrates antifibrotic effects on lung fibroblasts
Bogatkevich GS et al. · Arthritis and rheumatism
Added to ASH registry: 2026-05-28
Diabetes mellitus is associated with increased ex vivo-platelet aggregation and decreased response to aspirin - antithrombotic potential of ACE-inhibitors and AT1-antagonists
Skowasch et al. · Platelets
Added to ASH registry: 2026-05-28
Direct Factor Xa and direct thrombin inhibitors: a clinical trial update
Turpie AG · Current opinion in drug discovery & development
Added to ASH registry: 2026-05-28
Direct thrombin inhibitor prevents delayed graft function in a porcine model of renal transplantation
Giraud S et al. · Transplantation
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors in atrial fibrillation reloaded
Steffel J et al. · European heart journal
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors in patients with mechanical heart valves: ready for clinical trials?
Rupprecht HJ · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Dosing patterns and outcomes in African American, Asian, and Hispanic patients with heparin-induced thrombocytopenia treated with argatroban
Hursting et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Factor XI Deficiency
Duga et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Favorable therapeutic index of the direct factor Xa inhibitors, apixaban and rivaroxaban, compared with the thrombin inhibitor dabigatran in rabbits
Wong PC et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Fondaparinux: an overview
Nadar et al. · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-28
From heparin to EP217609: the long way to a new pentasaccharide-based neutralisable anticoagulant with an unprecedented pharmacological profile
Petitou M et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology.
Levi et al. · British journal of haematology
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia (HIT II) - a drug-associated autoimmune disease
Nowak · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Lessons from ximelagatran: issues for future studies evaluating new oral direct thrombin inhibitors for venous thromboembolism prophylaxis in orthopedic surgery
Lazo-Langner et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Mechanism of the anticoagulant activity of thrombin mutant W215A/E217A.
Gandhi PS et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Membrane-dependent interaction of factor Xa and prothrombin with factor Va in the prothrombinase complex.
Qureshi et al. · Biochemistry
Added to ASH registry: 2026-05-28
Molecular basis of thrombomodulin activation of slow thrombin.
Adams et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Mutagenesis studies toward understanding allostery in thrombin.
Qureshi et al. · Biochemistry
Added to ASH registry: 2026-05-28
Pharmacology, pharmacokinetics, and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor
Stangier J et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Recombinant hirudin treatment modulates aquaporin-4 and aquaporin-9 expression after intracerebral hemorrhage in vivo
Sun et al. · Molecular biology reports
Added to ASH registry: 2026-05-28
Rivaroxaban, the first oral, direct factor Xa inhibitor
Fassiadis et al. · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-28
Rivaroxaban: a novel, oral, direct factor Xa inhibitor
Abrams et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
The direct factor Xa inhibitor rivaroxaban
Verma et al. · The Medical journal of Australia
Added to ASH registry: 2026-05-28
Thrombelastography.
Reikvam et al. · Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
Added to ASH registry: 2026-05-28
Thrombin allosteric modulation revisited: a molecular dynamics study.
de Amorim et al. · Journal of molecular modeling
Added to ASH registry: 2026-05-28
Thrombosis during lepirudin therapy: a case report
Wallet et al. · Intensive care medicine
Added to ASH registry: 2026-05-28
Thrombotic thrombocytopenic purpura and heparin-induced thrombocytopenia: two unique causes of life-threatening thrombocytopenia
Marques · Clinics in laboratory medicine
Added to ASH registry: 2026-05-28
Weight-based argatroban dosing nomogram for treatment of heparin-induced thrombocytopenia
Ansara et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Whole blood platelet aggregometry and platelet function testing.
McGlasson et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
A long-lasting, plasmin-activatable thrombin inhibitor aids clot lysis in vitro and does not promote bleeding in vivo
Sheffield WP et al. · Thromb Haemost
Added to ASH registry: 2026-05-27
Batroxobin mobilizes circulating endothelial progenitor cells in patients with deep vein thrombosis
Zhang L et al. · Clinical and applied thrombosis/hemostasis
Added to ASH registry: 2026-05-27
Dabigatran: new drug. Continue to use heparin, a better-known option
Prescrire International et al. · Prescrire international
Added to ASH registry: 2026-05-27
Extremely low doses of lepirudin in a patient with heparin-induced thrombocytopenia, high bleeding risk and renal insufficiency
Tardy-Poncet B et al. · British journal of haematology
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia: when a low platelet count is a mandate for anticoagulation
Ortel TL · Hematology. American Society of Hematology. Education Program
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia. A contemporary clinical approach to diagnosis and management
Shantsila E et al. · Chest
Added to ASH registry: 2026-05-27
Inhibition of coagulation activation and inflammation by a novel Factor Xa inhibitor synthesized from the earthworm Eisenia andrei
Joo SS et al. · Biological & pharmaceutical bulletin
Added to ASH registry: 2026-05-27
Lepirudin-induced thrombocytopenia following subcutaneous administration
Schroeder WS et al. · American journal of health-system pharmacy
Added to ASH registry: 2026-05-27
Prefilter bivalirudin for preventing hemofilter occlusion in continuous renal replacement therapy
Mueller SW et al. · Annals of Pharmacotherapy
Added to ASH registry: 2026-05-27
Prolonged elevation of plasma argatroban in a cardiac transplant patient with a suspected history of heparin-induced thrombocytopenia with thrombosis
Genzen JR et al. · Transfusion
Added to ASH registry: 2026-05-27
Qualities of Whitmania pigra in different-month-age and best harvest time
Shi H et al. · Zhongguo Zhong Yao Za Zhi (China Journal of Chinese Materia Medica)
Added to ASH registry: 2026-05-27
Role of clopidogrel loading dose in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty: results from the HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trial
Dangas G et al. · J Am Coll Cardiol
Added to ASH registry: 2026-05-27
[Leech hirudo medicinalis: a therapeutic alternative available in Mexico]
Cornejo-Esquerra A et al. · Revista medica del Instituto Mexicano del Seguro Social
Added to ASH registry: 2026-03-18
[Medicinal leeches]
Massart D, Sohawon S, Noordally O · Revue medicale de Bruxelles
Added to ASH registry: 2026-03-18
Heparin-induced thrombocytopenia--therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4-heparin complexes
Krauel et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-29
Prolonged half-life of argatroban in patients with renal dysfunction and antiphospholipid antibody syndrome being treated for heparin-induced thrombocytopenia
Athar et al. · American journal of hematology
Added to ASH registry: 2026-05-29
Successful use of argatroban during the third trimester of pregnancy: case report and review of the literature
Young et al. · Pharmacotherapy
Added to ASH registry: 2026-05-29
The use of ecarin chromogenic assay and prothrombinase induced clotting time in the monitoring of lepirudin for the treatment of heparin-induced thrombocytopenia
Guy et al. · British journal of haematology
Added to ASH registry: 2026-05-29
Antithrombotics for PCI: an indigenous direct thrombin inhibitor (DTI) makes the cut
Mukherjee D · Indian heart journal
Added to ASH registry: 2026-05-28
Apixaban, an oral, direct inhibitor of activated Factor Xa
Shantsila et al. · Current opinion in investigational drugs (London, England : 2000)
Added to ASH registry: 2026-05-28
Argatroban therapy in patients with hepatic and renal impairment.
Brand et al. · European journal of anaesthesiology
Added to ASH registry: 2026-05-28
Bivalirudin decreases NO bioavailability by vascular immobilization of myeloperoxidase.
Rudolph V et al. · The Journal of pharmacology and experimental therapeutics
Added to ASH registry: 2026-05-28
Bivalirudin.
Warkentin et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate
Stangier J · Clinical pharmacokinetics
Added to ASH registry: 2026-05-28
Computational study of the putative active form of protein Z (PZa): sequence design and structural modeling.
Chandrasekaran V et al. · Protein science : a publication of the Protein Society
Added to ASH registry: 2026-05-28
Current and future prospects for anticoagulant therapy: inhibitors of factor Xa and factor IIa
Harenberg J et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Dabigatran etexilate
Sanford et al. · Drugs
Added to ASH registry: 2026-05-28
Dabigatran etexilate
Eriksson et al. · Nature reviews. Drug discovery
Added to ASH registry: 2026-05-28
Desirudin reduces the rate of microvenous thrombosis in a rat model
Lewis et al. · The Laryngoscope
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors: pharmacology and application in cardiovascular anesthesia
Kozek-Langenecker SA · Der Anaesthesist
Added to ASH registry: 2026-05-28
Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT)--bridging the River Coumarin
Warkentin TE · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Fondaparinux: use in thromboprophylaxis of acute medical patients
Dhillon et al. · Drugs & aging
Added to ASH registry: 2026-05-28
Fragment-based approach to drug lead discovery: overview and advances in various techniques.
Fattori D et al. · Drugs in R&D
Added to ASH registry: 2026-05-28
How Na+ activates thrombin--a review of the functional and structural data.
Huntington · Biological chemistry
Added to ASH registry: 2026-05-28
Lepirudin in the management of patients with heparin-induced thrombocytopenia
Petros · Biologics : targets & therapy
Added to ASH registry: 2026-05-28
Locking solutions for hemodialysis catheters; heparin and citrate--a position paper by ASDIN.
Moran et al. · Seminars in dialysis
Added to ASH registry: 2026-05-28
Management of uremic patients with heparin-induced thrombocytopenia requiring hemodialysis
Matsuo et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
New anticoagulant strategies in ST elevation myocardial infarction: trials and clinical implications
McCann CJ et al. · Vascular health and risk management
Added to ASH registry: 2026-05-28
New anticoagulants
Bauersachs RM · Hamostaseologie
Added to ASH registry: 2026-05-28
On designing non-saccharide, allosteric activators of antithrombin.
Raghuraman A et al. · European journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Orally administered factor xa inhibitor, rivaroxaban: a novel thromboembolic prophylaxis agent
Komotar et al. · Neurosurgery
Added to ASH registry: 2026-05-28
Pathogenesis, diagnosis, and management of disseminated intravascular coagulation: a literature review.
Dalainas · European review for medical and pharmacological sciences
Added to ASH registry: 2026-05-28
Peptides and pseudopeptides incorporating D-Phe-Pro-Arg and Arg-Gly-Asp lead sequences as potential antithrombotic agents
Ilas J et al. · Journal of peptide science : an official publication of the European Peptide Society
Added to ASH registry: 2026-05-28
Percutaneous coronary intervention in patients with acute coronary syndrome: focus on bivalirudin
Ramana RK et al. · Vascular health and risk management
Added to ASH registry: 2026-05-28
Pharmacokinetics and pharmacodynamics of the direct oral thrombin inhibitor dabigatran in healthy elderly subjects
Stangier et al. · Clinical pharmacokinetics
Added to ASH registry: 2026-05-28
Platelet GPIb complex as a target for anti-thrombotic drug development
Clemetson KJ et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Rivaroxaban, an oral direct factor Xa inhibitor
Piccini et al. · Expert opinion on investigational drugs
Added to ASH registry: 2026-05-28
Rotational thrombelastometry for the bedside monitoring of recombinant hirudin
Sucker et al. · Acta anaesthesiologica Scandinavica
Added to ASH registry: 2026-05-28
Structural identification of the pathway of long-range communication in an allosteric enzyme.
Gandhi PS et al. · Proceedings of the National Academy of Sciences of the United States of America
Added to ASH registry: 2026-05-28
The in vitro anticoagulant effects of danaparoid, fondaparinux, and lepirudin in children compared to adults
Ignjatovic et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Thrombin.
Di Cera E · Molecular aspects of medicine
Added to ASH registry: 2026-05-28
Update on atrial fibrillation: part I.
Savelieva I et al. · Clinical cardiology
Added to ASH registry: 2026-05-28
A novel hirudin derivative characterized with anti-platelet aggregations and thrombin inhibition
Mo W et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-27
A recombinant peptide, hirudin, potentiates the inhibitory effects of stealthy liposomal vinblastine on the growth and metastasis of melanoma
Guo RR et al. · Biological & pharmaceutical bulletin
Added to ASH registry: 2026-05-27
Bivalirudin for patients with heparin-induced thrombocytopenia undergoing cardiovascular surgery
Czosnowski QA et al. · Annals of Pharmacotherapy
Added to ASH registry: 2026-05-27
Brave new world: the current and future use of novel anticoagulants
Spyropoulos AC · Thrombosis Research
Added to ASH registry: 2026-05-27
Current view on alveolar coagulation and fibrinolysis in acute inflammatory and chronic interstitial lung diseases
Wygrecka M et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Decrease of hirudin degradation by deleting the KEX1 gene in recombinant Pichia pastoris
Ni Z et al. · Yeast (Chichester, England)
Added to ASH registry: 2026-05-27
Dosing lepirudin in patients with heparin-induced thrombocytopenia and normal or impaired renal function: a single-center experience with 68 patients
Tschudi M et al. · Blood
Added to ASH registry: 2026-05-27
Expression of recombinant Hirudin in transgenic mice milk driven by the goat beta-casein promoter
Yen CH et al. · Biotechnol J
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia complicated by warfarin-induced skin necrosis
Howard-Thompson A et al. · American journal of health-system pharmacy
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia: diagnosis and management
Hassell K · Thrombosis research
Added to ASH registry: 2026-05-27
Increase of the pharmacological and pharmacokinetic efficacy of negatively charged polypeptide recombinant hirudin in rats via parenteral route by association with cationic liposomes
Meng M et al. · Journal of controlled release : official journal of the Controlled Release Society
Added to ASH registry: 2026-05-27
Lepirudin in the management of heparin-induced thrombocytopenia
Gajra A et al. · Expert Opinion on Drug Metabolism & Toxicology
Added to ASH registry: 2026-05-27
Management of anticoagulation in patients with subacute heparin-induced thrombocytopenia scheduled for heart transplantation
Selleng S et al. · Blood
Added to ASH registry: 2026-05-27
New anticoagulant agents: direct thrombin inhibitors
Nutescu EA et al. · Cardiology Clinics
Added to ASH registry: 2026-05-27
Role of the acidic hirudin-like COOH-terminal amino acid region of factor Va heavy chain in the enhanced function of prothrombinase
Hirbawi J et al. · Biochemistry
Added to ASH registry: 2026-05-27
Standardizing the management of heparin-induced thrombocytopenia
Fugate S, Chiappe J · American journal of health-system pharmacy
Added to ASH registry: 2026-05-27
Structure of the leech protein saratin and characterization of its binding to collagen
Gronwald W et al. · Journal of molecular biology
Added to ASH registry: 2026-05-27
The direct thrombin inhibitor hirudin
Greinacher A, Warkentin T · Thrombosis and haemostasis
Added to ASH registry: 2026-03-18
Hemofiltration of recombinant hirudin by different hemodialyzer membranes: implications for clinical use
Benz et al. · Clinical journal of the American Society of Nephrology : CJASN
Added to ASH registry: 2026-05-29
Lepirudin for anticoagulation in patients with heparin-induced thrombocytopenia treated with continuous renal replacement therapy
Gajra et al. · American journal of hematology
Added to ASH registry: 2026-05-29
Long-term application of lepirudin on chronic haemodialysis over 34 months after heparin-induced thrombocytopenia
Gay et al. · Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Added to ASH registry: 2026-05-29
Severe anaphylactic reaction after repeated intermittent exposure to lepirudin
Veach et al. · Pharmacotherapy
Added to ASH registry: 2026-05-29
Thrombin-activated thrombelastography for evaluation of thrombin interaction with thrombin inhibitors
Taketomi et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-29
Use of continuous venovenous hemofiltration for reversal of anticoagulation with lepirudin post-cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia after heart transplantation
Saravanan et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-29
[Anticoagulation in continuous renal replacement therapies (CRRT)].
Garcés et al. · Revista da Associacao Medica Brasileira (1992)
Added to ASH registry: 2026-05-28
[Sodium ions as the effector of catalytic action of alpha-thrombin].
Kolodzeĭskaia MV et al. · Ukrains'kyi biokhimichnyi zhurnal (1999 )
Added to ASH registry: 2026-05-28
Anticoagulation for acute coronary syndromes: from heparin to direct thrombin inhibitors
Lepor NE · Reviews in cardiovascular medicine
Added to ASH registry: 2026-05-28
Anticoagulation options for patients with heparin-induced thrombocytopenia requiring renal support in the intensive care unit.
Davenport · Contributions to nephrology
Added to ASH registry: 2026-05-28
Antithrombotic and hemostatic effects of a small molecule factor XIa inhibitor in rats
Schumacher et al. · European journal of pharmacology
Added to ASH registry: 2026-05-28
Argatroban anticoagulation for heparin-induced thrombocytopenia in elderly patients
Bartholomew et al. · Drugs & aging
Added to ASH registry: 2026-05-28
Argatroban for anticoagulation during cardiac surgery
Martin et al. · European journal of haematology
Added to ASH registry: 2026-05-28
Argatroban in extracorporeal membrane oxygenation
Beiderlinden et al. · Artificial organs
Added to ASH registry: 2026-05-28
Argatroban therapy for heparin-induced thrombocytopenia in acutely ill patients
Gray et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Argatroban therapy in women with heparin-induced thrombocytopenia
Jang et al. · Journal of women's health (2002)
Added to ASH registry: 2026-05-28
Arterial and venous complications of heparin-induced thrombocytopenia in burn patients
Scott et al. · Journal of burn care & research : official publication of the American Burn Association
Added to ASH registry: 2026-05-28
Clot structure modification by fondaparinux and consequence on fibrinolysis: a new mechanism of antithrombotic activity
Varin R et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4.
Bah A et al. · Proceedings of the National Academy of Sciences of the United States of America
Added to ASH registry: 2026-05-28
Direct antithrombins: mechanisms, trials, and role in contemporary interventional medicine.
Wong CK et al. · American journal of cardiovascular drugs : drugs, devices, and other interventions
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors: alternatives to heparin
Mureebe L · Vascular
Added to ASH registry: 2026-05-28
Effects of unfractionated heparin and glycoprotein IIb/IIIa antagonists versus bivalirdin on myeloperoxidase release from neutrophils.
Li G et al. · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-28
Efficacy and safety of bivalirudin versus heparins in reduction of cardiac outcomes in acute coronary syndrome and percutaneous coronary interventions
Singh et al. · Journal of cardiovascular pharmacology and therapeutics
Added to ASH registry: 2026-05-28
Exosites in the substrate specificity of blood coagulation reactions.
Bock et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Fondaparinux as a treatment option for heparin-induced thrombocytopenia
Papadopoulos et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Glycoprotein IIb/IIIa inhibitor-induced thrombocytopenia: diagnosis and treatment
Said SM et al. · Clinical research in cardiology : official journal of the German Cardiac Society
Added to ASH registry: 2026-05-28
Heparin induced thrombocytopenia: diagnosis and management update
Ahmed et al. · Postgraduate medical journal
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia in a uremic patient requiring hemodialysis: an alternative treatment and reexposure to heparin
Matsuo et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia: treatment options and special considerations.
Dager et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate
Wienen et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates.
Gruber et al. · Blood
Added to ASH registry: 2026-05-28
Structural insight into distinct mechanisms of protease inhibition by antibodies.
Wu Y et al. · Proceedings of the National Academy of Sciences of the United States of America
Added to ASH registry: 2026-05-28
The direct thrombin inhibitor ximelagatran/melagatran: a systematic review on clinical applications and an evidence based assessment of risk benefit profile
Testa L et al. · Expert opinion on drug safety
Added to ASH registry: 2026-05-28
The discovery of the Factor Xa inhibitor otamixaban: from lead identification to clinical development
Guertin et al. · Current medicinal chemistry
Added to ASH registry: 2026-05-28
The haemostatic role of tissue factor pathway inhibitor.
Crawley et al. · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-28
The new anticoagulants
Stone WM et al. · Perspectives in vascular surgery and endovascular therapy
Added to ASH registry: 2026-05-28
The NMR solution structure of recombinant RGD-hirudin
Song et al. · Biochemical and biophysical research communications
Added to ASH registry: 2026-05-28
Biochemical and biological characterization of the venoms of Bothriopsis bilineata and Bothriopsis taeniata (Serpentes: Viperidae)
Porto BN et al. · Toxicon
Added to ASH registry: 2026-05-27
Bloodletting a popular form of treatment that disappeared
Keeman JN et al. · Nederlands tijdschrift voor geneeskunde
Added to ASH registry: 2026-05-27
Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin
Liu CC et al. · Journal of the American Chemical Society
Added to ASH registry: 2026-05-27
Hemorrhagic, coagulant and fibrino(geno)lytic activities of crude venom and fractions from mapanare (Bothrops colombiensis) snakes
Giron ME et al. · Comparative biochemistry and physiology Toxicology & pharmacology
Added to ASH registry: 2026-05-27
Heparin induced thrombocytopenia: pathogenetic, clinical, diagnostic and therapeutic aspects
Castelli R et al. · Cardiovascular & hematological disorders drug targets
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia and thrombosis
Patel VP et al. · American journal of orthopedics
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia in intensive care patients
Selleng K et al. · Critical Care Medicine
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia: a frequent complication after cardiac surgery
Pouplard C et al. · Archives des maladies du coeur et des vaisseaux
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia: a general review
Swanson JM · Journal of infusion nursing
Added to ASH registry: 2026-05-27
Identification and characterization of a new member of snake venom thrombin inhibitors from Bothrops insularis using a proteomic approach
Oliveira-Carvalho AL et al. · Toxicon
Added to ASH registry: 2026-05-27
Neutrophil interaction with the hemostatic system contributes to liver injury in rats cotreated with lipopolysaccharide and ranitidine
Deng X et al. · The Journal of pharmacology and experimental therapeutics
Added to ASH registry: 2026-05-27
Off-pump coronary artery bypass with bivalirudin for patients with heparin-induced thrombocytopenia or antiplatelet factor four/heparin antibodies
Dyke CM et al. · Annals of Thoracic Surgery
Added to ASH registry: 2026-05-27
Recombinant hirudin for cardiopulmonary bypass anticoagulation: a randomized, prospective, and heparin-controlled pilot study
Riess FC et al. · Thoracic and Cardiovascular Surgeon
Added to ASH registry: 2026-05-27
Studies on preparation of recombinant hirudin-2 liposome and its pharmacokinetics by nasal delivery in rats
Zhang YJ et al. · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Added to ASH registry: 2026-05-27
Suramin counteracts the haemostatic disturbances produced by Bothrops jararaca snake venom
Fernandes CM et al. · Toxicon
Added to ASH registry: 2026-05-27
The leech product saratin is a potent inhibitor of platelet integrin alpha2beta1 and von Willebrand factor binding to collagen
White TC et al. · FEBS J
Added to ASH registry: 2026-05-27
The place of chemical leeching with heparin in digital replantation
Yokoyama T et al. · Plastic and reconstructive surgery
Added to ASH registry: 2026-05-27
Thrombin induced tumour growth - pharmacological control
Nowak G et al. · Hamostaseologie
Added to ASH registry: 2026-05-27
[Hirudo medicinalis-leech applications in plastic and reconstructive microsurgery--a literature review]
Knobloch K et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...
Added to ASH registry: 2026-03-18
Hirudin--the long and stony way from an anticoagulant peptide in the saliva of medicinal leech to a recombinant drug and beyond. A historical piece
Nowak G, Schrör K · Thrombosis and haemostasis
Added to ASH registry: 2026-03-18
Delayed thrombin generation is not associated with fibrinopeptide formation during prolonged cardiopulmonary bypass with hirudin anticoagulation
Belway et al. · Perfusion
Added to ASH registry: 2026-05-29
[Mechanism of thrombosis: physiopathology, role of thrombin and its inhibition by modern therapies].
Hamon M · Archives des maladies du coeur et des vaisseaux
Added to ASH registry: 2026-05-28
Activated protein C and sepsis.
O'Brien et al. · Frontiers in bioscience : a journal and virtual library
Added to ASH registry: 2026-05-28
Adenovirus-mediated expression of the anticoagulant hirudin in human islets: a tool to make the islets biocompatible to blood
Cabric S et al. · Cell transplantation
Added to ASH registry: 2026-05-28
Argatroban anticoagulation in pediatric patients: a literature analysis
Hursting et al. · Journal of pediatric hematology/oncology
Added to ASH registry: 2026-05-28
Argatroban for suspected heparin-induced thrombocytopenia: contemporary experience at a large teaching hospital
Kodityal et al. · Journal of intensive care medicine
Added to ASH registry: 2026-05-28
Argatroban, a direct thrombin inhibitor for heparin-induced thrombocytopaenia: present and future perspectives
Serebruany et al. · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-28
Argatroban: a direct thrombin inhibitor with reliable and predictable anticoagulant actions
Escolar G et al. · Drugs of today (Barcelona, Spain : 1998)
Added to ASH registry: 2026-05-28
Bivalirudin in acute coronary syndromes and percutaneous coronary intervention
Lee MS et al. · Reviews in cardiovascular medicine
Added to ASH registry: 2026-05-28
Bivalirudin in peripheral interventions
Maclean et al. · Techniques in vascular and interventional radiology
Added to ASH registry: 2026-05-28
Clinical development of bivalirudin (Angiox): rationale for thrombin-specific anticoagulation in percutaneous coronary intervention and acute coronary syndromes
Serruys PW et al. · International journal of clinical practice
Added to ASH registry: 2026-05-28
Comparison of alteplase and heparin in maintaining the patency of paediatric central venous haemodialysis lines: a randomised controlled trial.
Gittins et al. · Archives of disease in childhood
Added to ASH registry: 2026-05-28
Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants
Lin J et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Determinants of specificity of factor xa interaction with its physiological inhibitors.
Rezaie · Mini reviews in medicinal chemistry
Added to ASH registry: 2026-05-28
Diagnosis and management of heparin-induced thrombocytopenia.
de Maistre et al. · Canadian journal of anaesthesia = Journal canadien d'anesthesie
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors - a survey of recent developments
Schwienhorst A · Cellular and molecular life sciences : CMLS
Added to ASH registry: 2026-05-28
Economic implications of bivalirudin in the cardiac catheterization laboratory.
Bakhai et al. · Reviews in cardiovascular medicine
Added to ASH registry: 2026-05-28
Emerging anticoagulants: mechanism of action and future potential.
Klement P et al. · Vnitrni lekarstvi
Added to ASH registry: 2026-05-28
Fibrin structure and wound healing.
Laurens et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Graded inhibitory synaptic transmission between leech interneurons: assessing the roles of two kinetically distinct low-threshold Ca currents
Ivanov AI et al. · Journal of neurophysiology
Added to ASH registry: 2026-05-28
Inherited thrombophilia.
Franchini et al. · Critical reviews in clinical laboratory sciences
Added to ASH registry: 2026-05-28
Investigation on recombinant hirudin via oral route
Cen et al. · Peptides
Added to ASH registry: 2026-05-28
New anticoagulants
Bauer KA · Hematology. American Society of Hematology. Education Program
Added to ASH registry: 2026-05-28
Presentation, management and outcomes of thrombosis for children with cardiomyopathy.
McCrindle et al. · The Canadian journal of cardiology
Added to ASH registry: 2026-05-28
Promotion of proinflammatory interactions between platelets and monocytes by unfractionated heparin.
Harding SA et al. · Heart (British Cardiac Society)
Added to ASH registry: 2026-05-28
Protein C anticoagulant activity in relation to anti-inflammatory and anti-apoptotic activities.
Mosnier et al. · Frontiers in bioscience : a journal and virtual library
Added to ASH registry: 2026-05-28
Safety and efficacy of argatroban in patients with heparin-induced thrombocytopenia
Matthai · Current hematology reports
Added to ASH registry: 2026-05-28
Spike-mediated and graded inhibitory synaptic transmission between leech interneurons: evidence for shared release sites
Ivanov AI et al. · Journal of neurophysiology
Added to ASH registry: 2026-05-28
Successful recovery after an overdose of argatroban
Yee et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
The cost-effectiveness of argatroban treatment in heparin-induced thrombocytopenia: the effect of early versus delayed treatment
Arnold et al. · Cardiology in review
Added to ASH registry: 2026-05-28
The cytoprotective protein C pathway.
Mosnier et al. · Blood
Added to ASH registry: 2026-05-28
The full-length cDNA of anticoagulant protein infestin revealed a novel releasable Kazal domain, a neutrophil elastase inhibitor lacking anticoagulant activity
Lovato et al. · Biochimie
Added to ASH registry: 2026-05-28
The structure of thrombin: a janus-headed proteinase
Bode W · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Thrombin-cofactor interactions: structural insights into regulatory mechanisms.
Adams TE et al. · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-28
Thrombotic end point for assessing argatroban therapy for heparin-induced thrombocytopenia: learning from secondary analyses of prospective studies
Warkentin · Chest
Added to ASH registry: 2026-05-28
Tissue factor pathway inhibitor: structure, biology and involvement in disease.
Lwaleed et al. · The Journal of pathology
Added to ASH registry: 2026-05-28
Treatment of heparin-induced thrombocytopenia in cardiovascular patients.
Matthai · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-28
Treatment of heparin-induced thrombocytopenia: is there a role for bivalirudin?
Seybert et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Ximelagatran: direct thrombin inhibitor
Ho SJ et al. · Vascular health and risk management
Added to ASH registry: 2026-05-28
[Clinical use of a new class of anticoagulant drugs: the direct thrombin inhibitors]
Puccio D et al. · G Ital Cardiol (Rome)
Added to ASH registry: 2026-05-27
A backseat driver
Schwab IR · The British journal of ophthalmology
Added to ASH registry: 2026-05-27
Bivalirudin in percutaneous coronary intervention
Lehman SJ et al. · Vascular health and risk management
Added to ASH registry: 2026-05-27
Counteracting effect of glycyrrhizin on the hemostatic abnormalities induced by Bothrops jararaca snake venom
Assafim M et al. · British journal of pharmacology
Added to ASH registry: 2026-05-27
Effect of renal function on argatroban therapy in heparin-induced thrombocytopenia
Guzzi LM et al. · Journal of Thrombosis and Thrombolysis
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia in the critical care setting: diagnosis and management
Napolitano LM et al. · Critical Care Medicine
Added to ASH registry: 2026-05-27
High-level secretion of dipetarudin, a chimeric thrombin inhibitor, by Pichia pastoris
Lopez M et al. · Protein Expr Purif
Added to ASH registry: 2026-05-27
Macrophage migration inhibitory factor and glucocorticoid sensitivity
Aeberli D et al. · Rheumatology (Oxford, England)
Added to ASH registry: 2026-05-27
MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis
Morand EF et al. · Nature reviews. Drug discovery
Added to ASH registry: 2026-05-27
N-terminal proteolytic processing by cathepsin G converts RANTES/CCL5 and related analogs into a truncated 4-68 variant
Lim JK et al. · Journal of leukocyte biology
Added to ASH registry: 2026-05-27
Predictive factors for thrombosis and major bleeding in an observational study in 181 patients with heparin-induced thrombocytopenia treated with lepirudin
Tardy B et al. · Blood
Added to ASH registry: 2026-05-27
Purification and properties of a coagulant thrombin-like enzyme from the venom of Bothrops leucurus
Magalhaes A et al. · Comparative biochemistry and physiology Part A Molecular & integrative physiology
Added to ASH registry: 2026-05-27
Recognition and management of heparin-induced thrombocytopenia in pediatric cardiopulmonary bypass patients
Boshkov LK et al. · Annals of Thoracic Surgery
Added to ASH registry: 2026-05-27
Use of heparin versus lepirudin flushes to prevent withdrawal occlusion of central venous access devices
Horne MK et al. · Pharmacotherapy
Added to ASH registry: 2026-05-27
von Willebrand factor A1 domain can adequately substitute for A3 domain in recruitment of flowing platelets to collagen
Bonnefoy A et al. · J Thromb Haemost
Added to ASH registry: 2026-05-27
A comparison of lepirudin and argatroban outcomes
Smythe et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
A review of the oral direct thrombin inhibitor ximelagatran: not yet the end of the warfarin era.
Mohapatra R et al. · American heart journal
Added to ASH registry: 2026-05-28
Antithrombin abnormalities and perinatal management.
Kobayashi · Current drug targets
Added to ASH registry: 2026-05-28
Are cost benefits of anticoagulation for stroke prevention in atrial fibrillation underestimated?
Miller et al. · Stroke
Added to ASH registry: 2026-05-28
Argatroban and lepirudin: clinical trials to clinical practice
Messmore et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Argatroban and renal replacement therapy in patients with heparin-induced thrombocytopenia.
Tang et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Bivalirudin: a review of its use in patients undergoing percutaneous coronary intervention
Moen MD et al. · Drugs
Added to ASH registry: 2026-05-28
Bivalirudin: role in current percutaneous coronary intervention practice
West N · British journal of hospital medicine (London, England : 2005)
Added to ASH registry: 2026-05-28
Chemical synthesis of the RGD-protein decorsin: Pro-->Ala replacement reduces protein thermostability.
Frare E et al. · Protein engineering, design & selection : PEDS
Added to ASH registry: 2026-05-28
Determinants of specificity in coagulation proteases.
Page et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Direct thrombin inhibitor use during percutaneous coronary intervention
Kokolis S et al. · Journal of cardiovascular pharmacology
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors
Di Nisio M et al. · The New England journal of medicine
Added to ASH registry: 2026-05-28
Directing thrombin.
Lane DA et al. · Blood
Added to ASH registry: 2026-05-28
Effect of hirudin versus heparin on hemocompatibility of blood contacting biomaterials: an in vitro study
Kopp R et al. · The International journal of artificial organs
Added to ASH registry: 2026-05-28
Effect of lepirudin on the international normalized ratio
Stephens et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Evaluation of diagnostic tests and argatroban or lepirudin therapy in patients with suspected heparin-induced thrombocytopenia
Kiser et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Fondaparinux: an update on new study results
Bauersachs · European journal of clinical investigation
Added to ASH registry: 2026-05-28
Functional mapping of charged residues of the 82-116 sequence in factor Xa: evidence that lysine 96 is a factor Va independent recognition site for prothrombin in the prothrombinase complex.
Manithody et al. · Biochemistry
Added to ASH registry: 2026-05-28
Glucocorticosteroids for primary biliary cirrhosis.
Prince et al. · The Cochrane database of systematic reviews
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia from venous thromboembolism treatment
Begelman et al. · Journal of internal medicine
Added to ASH registry: 2026-05-28
Hirudin binding reveals key determinants of thrombin allostery.
Mengwasser KE et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Hirudin-based anticoagulant strategy during isolated limb perfusion in a patient with heparin-induced thrombocytopenia
Lindemann W et al. · Melanoma research
Added to ASH registry: 2026-05-28
In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design
Costanzo MJ et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Lepirudin in patients with heparin-induced thrombocytopenia - results of the third prospective study (HAT-3) and a combined analysis of HAT-1, HAT-2, and HAT-3.
Lubenow et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Lepirudin: is the approved dosing schedule too high?
Hacquard et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Mechanism of action of the oral direct thrombin inhibitor ximelagatran
Mattsson C et al. · Seminars in vascular medicine
Added to ASH registry: 2026-05-28
Mechanisms of postinhibitory rebound and its modulation by serotonin in excitatory swim motor neurons of the medicinal leech
Angstadt JD et al. · Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology
Added to ASH registry: 2026-05-28
Minimizing the incidence of heparin-induced thrombocytopenia: to heparinize or not to heparinize vascular access?
Chow et al. · Paediatric anaesthesia
Added to ASH registry: 2026-05-28
Modulators of the coagulation cascade: focus and recent advances in inhibitors of tissue factor, factor VIIa and their complex
Frédérick R et al. · Current medicinal chemistry
Added to ASH registry: 2026-05-28
Molecular design and characterization of recombinant long half-life mutants of human tissue factor pathway inhibitor.
Bai H et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
New anticoagulants
Weitz JI et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Pharmacodynamics and pharmacokinetics of recombinant hirudin via four non-parenteral routes
Liu et al. · Peptides
Added to ASH registry: 2026-05-28
Pharmacology and clinical potential of direct thrombin inhibitors
Linkins LA et al. · Current pharmaceutical design
Added to ASH registry: 2026-05-28
Short- and long-acting synthetic pentasaccharides as antithrombotic agents
Walenga JM et al. · Expert opinion on investigational drugs
Added to ASH registry: 2026-05-28
Studies on the basis for the properties of fibrin produced from fibrinogen-containing gamma' chains.
Siebenlist KR et al. · Blood
Added to ASH registry: 2026-05-28
The management of patients with heparin-induced thrombocytopenia who require anticoagulant therapy
Hassell · Chest
Added to ASH registry: 2026-05-28
The Na+ binding channel of human coagulation proteases: novel insights on the structure and allosteric modulation revealed by molecular surface analysis.
Silva et al. · Biophysical chemistry
Added to ASH registry: 2026-05-28
The safety of fondaparinux for the prevention and treatment of venous thromboembolism
Turpie · Expert opinion on drug safety
Added to ASH registry: 2026-05-28
Thrombin, an ideal target for pharmacological inhibition: a review of direct thrombin inhibitors
Gurm HS et al. · American heart journal
Added to ASH registry: 2026-05-28
Thrombosis of the cerebral veins and sinuses.
Stam · The New England journal of medicine
Added to ASH registry: 2026-05-28
Treatment of patients with a history of heparin-induced thrombocytopenia and anti-lepirudin antibodies with argatroban
Harenberg et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Ximelagatran: an orally active direct thrombin inhibitor
Gulseth MP · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Anticoagulant use in patients with chronic renal impairment
Grand'Maison A et al. · American Journal of Cardiovascular Drugs
Added to ASH registry: 2026-05-27
Delayed-onset heparin-induced thrombocytopenia
Smythe MA et al. · Annals of emergency medicine
Added to ASH registry: 2026-05-27
Design, synthesis and structure-activity relationship of a series of fragment analogues of antistasin (ATS) and ghilantens (GLS)
Danalev DL et al. · Bioorganic & medicinal chemistry letters
Added to ASH registry: 2026-05-27
Differences between human proteinase 3 and neutrophil elastase and their murine homologues are relevant for murine model experiments
Wiesner O et al. · FEBS letters
Added to ASH registry: 2026-05-27
Direct thrombin inhibitors for treatment of heparin induced thrombocytopenia, deep vein thrombosis and atrial fibrillation
Francis CW · Current Pharmaceutical Design
Added to ASH registry: 2026-05-27
Evolving management strategies for heparin-induced thrombocytopenia
Rice L · Seminars in hematology
Added to ASH registry: 2026-05-27
Extensive prolongation of aPTT with argatroban in an elderly patient with improving renal function, normal hepatic enzymes, and metastatic lung cancer
Kubiak DW et al. · Annals of Pharmacotherapy
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia with acute aortic and renal thrombosis in a patient treated with low-molecular-weight heparin
Chevalier J et al. · European journal of vascular and endovascular surgery
Added to ASH registry: 2026-05-27
History of evidence-based medicine. Oranges, chloride of lime and leeches: barriers to teaching old dogs new tricks
Doherty S et al. · Emergency medicine Australasia
Added to ASH registry: 2026-05-27
Improvement of the specificity of dipetarudin by site directed mutagenesis
Lpez M et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Neuropeptide-derived antimicrobial peptides from invertebrates for biomedical applications
Salzet M et al. · Current medicinal chemistry
Added to ASH registry: 2026-05-27
The new antithrombotic agents
Meyer Samama M et al. · Presse medicale
Added to ASH registry: 2026-05-27
Thrombin-directed inhibitors: pharmacology and clinical use
White CM · American heart journal
Added to ASH registry: 2026-05-27
Thrombocytopenia and platelet hypoaggregation induced by Bothrops asper snake venom. Toxins involved and their contribution to metalloproteinase-induced pulmonary hemorrhage
Rucavado A et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Bivalirudin: a review
Warkentin TE, Koster A · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-26
Bivalirudin: pharmacology and clinical applications
Shammas NW · Cardiovascular drug reviews
Added to ASH registry: 2026-05-26
By what mechanism do leeches help to salvage ischaemic tissues? A review
Whitaker IS et al. · The British journal of oral & maxillofacial surgery
Added to ASH registry: 2026-05-26
Peptidomimetic thrombin inhibitors
Kikelj D · Pathophysiology of haemostasis and thrombosis
Added to ASH registry: 2026-05-26
Leech therapy: a history
Hyson J · Journal of the history of dentistry
Added to ASH registry: 2026-03-18
A synthetic antithrombin III binding pentasaccharide is now a drug! What comes next?
Petitou M et al. · Angewandte Chemie (International ed. in English)
Added to ASH registry: 2026-05-28
Antibodies against lepirudin are polyspecific and recognize epitopes on bivalirudin
Eichler et al. · Blood
Added to ASH registry: 2026-05-28
Anticoagulant efficacy of PEG-Hirudin in patients on maintenance hemodialysis
Pöschel KA et al. · Kidney international
Added to ASH registry: 2026-05-28
Argatroban dosing in intensive care patients with acute renal failure and liver dysfunction.
Williamson et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Argatroban therapy for antithrombin deficiency and mesenteric thrombosis: case report and review of the literature
Dager et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Bivalirudin: an anticoagulant option for percutaneous coronary intervention
Bates ER · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-28
Bleeding profiles of anticoagulants, including the novel oral direct thrombin inhibitor ximelagatran: definitions, incidence and management
Bergqvist et al. · European journal of haematology
Added to ASH registry: 2026-05-28
Characterization of the postglomerular renal metabolism of lepirudin in healthy volunteers
Kautzleben et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Combined Abciximab REteplase Stent Study in acute myocardial infarction (CARESS in AMI).
Di Mario C et al. · American heart journal
Added to ASH registry: 2026-05-28
Crystal structure of anticoagulant thrombin variant E217K provides insights into thrombin allostery.
Carter et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Crystallization, data collection and phasing of infestin 4, a factor XIIa inhibitor
Campos et al. · Acta crystallographica. Section D, Biological crystallography
Added to ASH registry: 2026-05-28
Developing an algorithm for treating heparin-induced thrombocytopenia.
McIntosh · Clinical advances in hematology & oncology : H&O
Added to ASH registry: 2026-05-28
Differential activation and inhibition of human platelet thrombin receptors by structurally distinct alpha-, beta- and gamma-thrombin
Soslau G et al. · Platelets
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors
Fritsma GA · Clinical laboratory science : journal of the American Society for Medical Technology
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors for anticoagulation
Nutescu EA et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Effect of direct thrombin inhibitors, bivalirudin, lepirudin, and argatroban, on prothrombin time and INR values
Gosselin et al. · American journal of clinical pathology
Added to ASH registry: 2026-05-28
Factor Xa inhibitors
Walenga et al. · Methods in molecular medicine
Added to ASH registry: 2026-05-28
Fondaparinux sodium: a review of its use in the prevention of venous thromboembolism following major orthopaedic surgery
Reynolds et al. · Drugs
Added to ASH registry: 2026-05-28
Fondaparinux: a Factor Xa inhibitor for antithrombotic therapy
Turpie · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-28
Fondaparinux: a new synthetic and selective inhibitor of Factor Xa
Bauer · Best practice & research. Clinical haematology
Added to ASH registry: 2026-05-28
Full or partial substitution of the reactive center loop of alpha-1-proteinase inhibitor by that of heparin cofactor II: P1 Arg is required for maximal thrombin inhibition
Filion ML et al. · Biochemistry
Added to ASH registry: 2026-05-28
Functional properties of a recombinant chimeric plasminogen activator with platelet-targeted fibrinolytic and anticoagulant potential.
Zhang L et al. · Molecular genetics and metabolism
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia: recognition, treatment, and prevention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
Warkentin et al. · Chest
Added to ASH registry: 2026-05-28
Identification and characterization of a novel factor XIIa inhibitor in the hematophagous insect, Triatoma infestans (Hemiptera: Reduviidae)
Campos et al. · FEBS letters
Added to ASH registry: 2026-05-28
Improvement of recombinant hirudin production by controlling NH4+ concentration in Pichia pastoris fermentation
Yang et al. · Biotechnology letters
Added to ASH registry: 2026-05-28
Lepirudin anaphylaxis and Kounis syndrome
Koutsojannis et al. · Circulation
Added to ASH registry: 2026-05-28
Lepirudin for prophylaxis of thrombosis in patients with acute isolated heparin-induced thrombocytopenia: an analysis of 3 prospective studies.
Lubenow et al. · Blood
Added to ASH registry: 2026-05-28
Lepirudin prevents lethal effects of Shiga toxin in a canine model
Raife et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Lepirudin therapy for thrombotic complications in congenital afibrinogenaemia
Schuepbach et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Lepirudin: a bivalent direct thrombin inhibitor for anticoagulation therapy
Greinacher A · Expert review of cardiovascular therapy
Added to ASH registry: 2026-05-28
Molecular dissection of Na+ binding to thrombin.
Pineda et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Penthalaris, a novel recombinant five-Kunitz tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick vector of Lyme disease, Ixodes scapularis.
Francischetti IM et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Pharmacokinetics of recombinant hirudin in healthy horses
Feige et al. · Equine veterinary journal
Added to ASH registry: 2026-05-28
Plasma fibrinogen.
Lowe et al. · Annals of clinical biochemistry
Added to ASH registry: 2026-05-28
Purification and identification of recombinant hirudin and its degradation products expressed in Pichia pastoris.
Zhou WB et al. · Preparative biochemistry & biotechnology
Added to ASH registry: 2026-05-28
Rational design and selection of bivalent peptide ligands of thrombin incorporating P4-P1 tetrapeptide sequences: from good substrates to potent inhibitors.
Su Z et al. · Protein engineering, design & selection : PEDS
Added to ASH registry: 2026-05-28
Recombinant hirudin enhances cardiac output and decreases systemic vascular resistance during reperfusion after cardiopulmonary bypass in a porcine model
Jormalainen et al. · The Journal of thoracic and cardiovascular surgery
Added to ASH registry: 2026-05-28
Small-molecule direct antithrombins: argatroban
Fareed et al. · Best practice & research. Clinical haematology
Added to ASH registry: 2026-05-28
Stroke in patients with heparin-induced thrombocytopenia and the effect of argatroban therapy
LaMonte et al. · Critical care medicine
Added to ASH registry: 2026-05-28
The direct thrombin inhibitor melagatran/ximelagatran
Brighton TA · The Medical journal of Australia
Added to ASH registry: 2026-05-28
The effect of anticoagulation with subcutaneously delivered polyethylene glycol conjugated hirudin and recombinant tissue plasminogen activator on recurrent stenosis in the rabbit double-balloon injury model
Alexander et al. · Thrombosis research
Added to ASH registry: 2026-05-28
The heparin binding properties of heparin cofactor II suggest an antithrombin-like activation mechanism
O'Keeffe D et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
The use of direct thrombin inhibitors in cardiovascular surgery in patients with heparin-induced thrombocytopenia.
Greinacher · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Thrombolysis and adjunctive therapy in acute myocardial infarction: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
Menon V et al. · Chest
Added to ASH registry: 2026-05-28
Ximelagatran: a novel oral direct thrombin inhibitor for long-term anticoagulation
McCullough PA et al. · Reviews in cardiovascular medicine
Added to ASH registry: 2026-05-28
Ximelagatran: the first oral direct thrombin inhibitor
Crowther et al. · Expert opinion on investigational drugs
Added to ASH registry: 2026-05-28
Adjunctive use of direct thrombin inhibitors in patients receiving fibrinolytic therapy for acute myocardial infarction
French JK et al. · American Journal of Cardiovascular Drugs
Added to ASH registry: 2026-05-27
Antithrombotic effects of saratin on human atherosclerotic plaques
Vilahur G et al. · Thromb Haemost
Added to ASH registry: 2026-05-27
Clinical potential of oral direct thrombin inhibitors in the prevention and treatment of venous thromboembolism
Agnelli G · Drugs
Added to ASH registry: 2026-05-27
Direct antithrombins: new perspectives in cardiovascular medicine
Lettino M et al. · Current medicinal chemistry. Cardiovascular and hematological agents
Added to ASH registry: 2026-05-27
Early onset of heparin-induced thrombocytopenia with thrombosis after open heart surgery: importance of an early diagnosis and Lepirudin treatment
Paparella D et al. · Blood coagulation & fibrinolysis
Added to ASH registry: 2026-05-27
Lepirudin in heparin-induced thrombocytopenia and extracorporeal membranous oxygenation
Dager WE et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-27
Molecular mapping of the thrombin-heparin cofactor II complex
Fortenberry YM et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-27
Prevention of venous thromboembolism following orthopaedic surgery: clinical potential of direct thrombin inhibitors
Eriksson BI et al. · Drugs
Added to ASH registry: 2026-05-27
Recombinant destabilase-lysozyme: synthesis de novo in E. coli and action mechanism of the enzyme expressed in Spodoptera frugiperda
Zavalova LL et al. · Biochemistry (Mosc)
Added to ASH registry: 2026-05-27
Saratin (an inhibitor of platelet-collagen interaction) decreases platelet aggregation and homocysteine-mediated postcarotid endarterectomy intimal hyperplasia in a dose-dependent manner
Davis JA et al. · Am J Surg
Added to ASH registry: 2026-05-27
Two engineered eglin c mutants potently and selectively inhibiting kexin or furin
Liu Z et al. · FEBS letters
Added to ASH registry: 2026-05-27
Hirudo medicinalis: ancient origins of, and trends in the use of medicinal leeches throughout history
Whitaker IS et al. · The British journal of oral & maxillofacial surgery
Added to ASH registry: 2026-05-26
The role of recombinant hirudins in the management of thrombotic disorders
Fischer KG · BioDrugs
Added to ASH registry: 2026-05-26
Bivalent direct thrombin inhibitors: hirudin and bivalirudin
Warkentin T · Best practice & research. Clinical haematology
Added to ASH registry: 2026-03-18
Anaphylactic and anaphylactoid reactions associated with lepirudin in patients with heparin-induced thrombocytopenia
Greinacher et al. · Circulation
Added to ASH registry: 2026-05-28
Anti-hirudin antibodies alter pharmacokinetics and pharmacodynamics of recombinant hirudin
Fischer et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Antithrombotic properties of a direct thrombin inhibitor with a prolonged half-life and AT-mediated factor Xa inhibitory activity
Vogel GM et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Argatroban anticoagulation in patients with heparin-induced thrombocytopenia
Lewis et al. · Archives of internal medicine
Added to ASH registry: 2026-05-28
Argatroban dosing in patients with heparin-induced thrombocytopenia.
Verme-Gibboney CN et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Argatroban inhibits staphylothrombin
Hijikata-Okunomiya et al. · Journal of thrombosis and haemostasis : JTH
Added to ASH registry: 2026-05-28
Argatroban, a new treatment option for heparin-induced thrombocytopenia
Cleveland KW · Critical care nurse
Added to ASH registry: 2026-05-28
Beneficial effects of immediate stenting after thrombolysis in acute myocardial infarction.
Scheller B et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
Benefit-risk assessment of treatments for heparin-induced thrombocytopenia
Messmore et al. · Drug safety
Added to ASH registry: 2026-05-28
Bivalirudin in percutaneous coronary intervention
Caron MF et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Bivalirudin provides increasing benefit with decreasing renal function: a meta-analysis of randomized trials
Chew et al. · The American journal of cardiology
Added to ASH registry: 2026-05-28
Bivalirudin, thrombin and platelets: clinical implications and future directions.
Becker R et al. · The Journal of invasive cardiology
Added to ASH registry: 2026-05-28
Clinical utility of subcutaneous hirudins.
Deitcher SR · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Combination platelet glycoprotein IIb/IIIa receptor and lepirudin administration during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia
Pinto et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Added to ASH registry: 2026-05-28
Design, parallel synthesis, and crystal structures of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex
Parlow JJ et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Dextran-related complications in head and neck microsurgery: do the benefits outweigh the risks? A prospective randomized analysis.
Disa et al. · Plastic and reconstructive surgery
Added to ASH registry: 2026-05-28
Direct thrombin inhibitor melagatran followed by oral ximelagatran in comparison with enoxaparin for prevention of venous thromboembolism after total hip or knee replacement
Eriksson BI et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Direct thrombin inhibitor therapy in the cardiovascular patient.
Chesebro JH · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Directed evolution towards protease-resistant hirudin variants.
Wirsching F et al. · Molecular genetics and metabolism
Added to ASH registry: 2026-05-28
Discovery of potent peptide-mimetic antagonists for the human thrombin receptor, protease-activated receptor-1 (PAR-1)
Maryanoff BE et al. · Current medicinal chemistry. Cardiovascular and hematological agents
Added to ASH registry: 2026-05-28
Early thrombolysis for the treatment of acute myocardial infarction: a systematic review and economic evaluation.
Boland A et al. · Health technology assessment (Winchester, England)
Added to ASH registry: 2026-05-28
Effects of lepirudin, argatroban and melagatran and additional influence of phenprocoumon on ecarin clotting time
Fenyvesi et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Efficacious and orally bioavailable thrombin inhibitors based on a 2,5-thienylamidine at the P1 position: discovery of N-carboxymethyl-d-diphenylalanyl-l-prolyl[(5-amidino-2-thienyl)methyl]amide
Lee K et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Engineering of a staphylokinase-based fibrinolytic agent with antithrombotic activity and targeting capability toward thrombin-rich fibrin and plasma clots.
Lian et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Engineering the proteolytic specificity of activated protein C improves its pharmacological properties.
Berg et al. · Proceedings of the National Academy of Sciences of the United States of America
Added to ASH registry: 2026-05-28
Evolving role of bivalirudin in percutaneous coronary interventions; impact of the REPLACE-2 study
Salam · Expert opinion on investigational drugs
Added to ASH registry: 2026-05-28
Excessive argatroban anticoagulation for heparin-induced thrombocytopenia
Reichert et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Fondaparinux for prevention of venous thromboembolism in major orthopedic surgery
Tran et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Fondaparinux, the first selective factor Xa inhibitor
Turpie et al. · Current opinion in hematology
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia--recognition and treatment.
Miller · AORN journal
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia: twenty-nine years later
Shuster et al. · Journal of vascular surgery
Added to ASH registry: 2026-05-28
Lepirudin use in a neonate with heparin-induced thrombocytopenia
Nguyen et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Management of heparin-induced thrombocytopenia: a critical comparison of lepirudin and argatroban.
Warkentin · Thrombosis research
Added to ASH registry: 2026-05-28
New developments in diagnosis and treatment of heparin-induced thrombocytopenia
Lubenow · Pathophysiology of haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Non-peptidic small-molecule antagonists of the human platelet thrombin receptor PAR-1
Selnick HG et al. · Current medicinal chemistry. Cardiovascular and hematological agents
Added to ASH registry: 2026-05-28
Oral direct thrombin inhibitors in clinical development
Gustafsson D · Journal of internal medicine
Added to ASH registry: 2026-05-28
Overview of heparin-induced thrombocytopenia.
Spinler et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Platelet function assays.
Rand et al. · Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
Added to ASH registry: 2026-05-28
Potential pharmacological applications of the antithrombotic molecule high molecular weight kininogen
Chavakis T et al. · Current vascular pharmacology
Added to ASH registry: 2026-05-28
Should bivalirudin replace heparin during percutaneous coronary interventions?
Antman · JAMA
Added to ASH registry: 2026-05-28
Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex
South MS et al. · Bioorganic & medicinal chemistry letters
Added to ASH registry: 2026-05-28
The evolving role of direct thrombin inhibitors in acute coronary syndromes
Eikelboom et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
The molecular basis of thrombin allostery revealed by a 1.8 A structure of the "slow" form.
Huntington et al. · Structure (London, England : 1993)
Added to ASH registry: 2026-05-28
Treatment options for heparin-induced thrombocytopenia.
Greinacher · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Added to ASH registry: 2026-05-28
Use of lepirudin during percutaneous vascular interventions in patients with heparin-induced thrombocytopenia.
Cochran et al. · The Journal of invasive cardiology
Added to ASH registry: 2026-05-28
Coexpression of BiP increased antithrombotic hirudin production in recombinant Saccharomyces cerevisiae
Kim MD et al. · J Biotechnol
Added to ASH registry: 2026-05-27
Direct thrombin inhibitors
Kaplan KL · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-27
Effect of plant Kunitz inhibitors from Bauhinia bauhinioides and Bauhinia rufa on pulmonary edema caused by activated neutrophils
Neuhof C et al. · Biological chemistry
Added to ASH registry: 2026-05-27
Novel anticoagulants for the prevention and treatment of venous thromboembolism
Weltermann A et al. · Wiener medizinische Wochenschrift (1946)
Added to ASH registry: 2026-05-27
The neurite-stimulating influence of components of medicinal leech salivary gland secretions in organotypic culture of spinal ganglia
Chalisova NI et al. · Neuroscience and behavioral physiology
Added to ASH registry: 2026-05-27
The present and future of heparin, low molecular weight heparins, pentasaccharide, and hirudin for venous thromboembolism and acute coronary syndromes
Haas S et al. · Seminars in vascular medicine
Added to ASH registry: 2026-05-27
Management of thrombotic and cardiovascular disorders in the new millenium
Fareed J, Hoppensteadt DA, Bick RL · Clinical and applied thrombosis/hemostasis
Added to ASH registry: 2026-05-26
A 2-sulfated, 3-linked alpha-L-galactan is an anticoagulant polysaccharide
Pereira MS et al. · Carbohydrate research
Added to ASH registry: 2026-05-28
Activated partial thromboplastin time is more sensitive than ecarin clotting time for monitoring low doses of desirudin
Mazoyer et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Anticoagulation with bivalirudin during cardiopulmonary bypass in cardiac surgery
Vasquez et al. · The Annals of thoracic surgery
Added to ASH registry: 2026-05-28
Anticoagulation with recombinant hirudin and danaparoid sodium in pediatric patients
Severin et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Argatroban
Kathiresan S et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Argatroban in HIT type II and acute coronary syndrome
Lewis et al. · Pathophysiology of haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Argatroban in thrombotic stroke
LaMonte et al. · Pathophysiology of haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Biological relevance of anti-recombinant hirudin antibodies--results from in vitro and in vivo studies
Liebe et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Bivalirudin: a direct thrombin inhibitor for percutaneous transluminal coronary angioplasty
Wiggins et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Bivalirudin: a review of its potential place in the management of acute coronary syndromes
Carswell et al. · Drugs
Added to ASH registry: 2026-05-28
Clinical monitoring of direct thrombin inhibitors using the ecarin clotting time
de Denus S et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism.
Baglin TP et al. · Proceedings of the National Academy of Sciences of the United States of America
Added to ASH registry: 2026-05-28
Development of argatroban as an anticoagulant and antithrombin agent in Japan
Ikoma et al. · Pathophysiology of haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors
Kaplan KL et al. · Seminars in hematology
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors
Weitz JI et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors in acute coronary syndromes: principal results of a meta-analysis based on individual patients' data
Direct et al. · Lancet (London, England)
Added to ASH registry: 2026-05-28
Effect of phenprocoumon on monitoring of lepirudin, argatroban, melagatran and unfractionated heparin with the PiCT method
Fenyvesi et al. · Pathophysiology of haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Effects of a synthetic factor Xa inhibitor (JTV-803) on various laboratory tests
Tobu et al. · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Added to ASH registry: 2026-05-28
Feasibility and timing of prehospital administration of reteplase in patients with acute myocardial infarction.
Rosenberg DG et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Fondaparinux: a new antithrombotic agent
Cheng · Clinical therapeutics
Added to ASH registry: 2026-05-28
Fondaparinux: a synthetic heparin pentasaccharide as a new antithrombotic agent
Walenga et al. · Expert opinion on investigational drugs
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia: pathophysiology and management
Mureebe et al. · Vascular and endovascular surgery
Added to ASH registry: 2026-05-28
Influence of lepirudin, argatroban, and melagatran on prothrombin time and additional effect of oral anticoagulation
Fenyvesi et al. · Clinical chemistry
Added to ASH registry: 2026-05-28
Lepirudin anticoagulation for heparin-induced thrombocytopenia
Deitcher et al. · The Journal of pediatrics
Added to ASH registry: 2026-05-28
Noncovalent tripeptidic thrombin inhibitors incorporating amidrazone, amine and amidine functions at P1
Lee K et al. · Bioorganic & medicinal chemistry letters
Added to ASH registry: 2026-05-28
Pharmacokinetics of new synthetic heparin mimetics
Hérault JP et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Pharmacology and clinical use of bivalirudin
Sciulli et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Platelet aggregation in different antithrombotic regimens. Possible proaggregant effect of low level oral anticoagulation
Perez et al. · Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
Added to ASH registry: 2026-05-28
Point of care measurement of lepirudin and heparin anticoagulation during systemic inflammation
Homoncik et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Practical issues in the development of argatroban: a perspective
Fareed et al. · Pathophysiology of haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Removal of lepirudin, a recombinant hirudin, by hemodialysis, hemofiltration, or plasmapheresis
Willey et al. · Pharmacotherapy
Added to ASH registry: 2026-05-28
Unique overlap in the prerequisites for thrombin inhibition and oral bioavailability resulting in potent oral antithrombotics
Adang AE et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Bivalirudin administration during percutaneous coronary intervention: emphasis on high-risk patients
Seybert AL · Pharmacotherapy
Added to ASH registry: 2026-05-27
Bivalirudin pharmacokinetics and pharmacodynamics: effect of renal function, dose, and gender
Robson R et al. · Clinical Pharmacology and Therapeutics
Added to ASH registry: 2026-05-27
Current agents for the treatment of patients with heparin-induced thrombocytopenia
Warkentin TE · Current opinion in pulmonary medicine
Added to ASH registry: 2026-05-27
Desirudin (Revasc) to prevent thromboembolic complications after hip or knee replacement surgery
Heiz-Valle C et al. · Therapie
Added to ASH registry: 2026-05-27
Hirudins in the treatment of heparin-induced thrombocytopenia and in thrombosis prophylaxis
Lubenow N et al. · Hamostaseologie
Added to ASH registry: 2026-05-27
Neutrophil elastase and acute lung injury: prospects for sivelestat and other neutrophil elastase inhibitors as therapeutics
Zeiher BG et al. · Critical care medicine
Added to ASH registry: 2026-05-27
Treatment of heparin-induced thrombocytopenia
Dager WE et al. · Ann Pharmacother
Added to ASH registry: 2026-05-27
Antihirudin antibodies following low-dose subcutaneous treatment with desirudin for thrombosis prophylaxis after hip-replacement surgery
Greinacher A, Eichler P, Albrecht D, Strobel U, Pötzsch B, Eriksson BI · Blood
Added to ASH registry: 2026-05-26
Bivalirudin: a direct thrombin inhibitor
Gladwell TD · Clinical therapeutics
Added to ASH registry: 2026-05-26
Bivalirudin: an anticoagulant for acute coronary syndromes and coronary interventions
White HD, Chew DP · Expert opinion on pharmacotherapy
Added to ASH registry: 2026-05-26
Probing the hirudin-thrombin interaction by incorporation of noncoded amino acids and molecular dynamics simulation
De Filippis V, Colombo G, Russo I, Spadari B, Fontana A · Biochemistry
Added to ASH registry: 2026-05-26
Hirudin and its reversal
Dornan R · British journal of anaesthesia
Added to ASH registry: 2026-03-18
Hirudin as alternative anticoagulant--a historical review
Markwardt F · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-03-18
Hirudin in heparin-induced thrombocytopenia
Lubenow N, Greinacher A · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-03-18
Hirudin in renal insufficiency
Fischer K · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-03-18
Pharmacology of recombinant hirudin
Nowak G · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-03-18
[Decolorization and isolation of recombinant hirudin expressed in the methylotrophic yeast Pichia pastoris].
Zhou WB et al. · Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Added to ASH registry: 2026-05-28
A comparison of danaparoid and lepirudin in heparin-induced thrombocytopenia.
Farner et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
A synopsis of the clinical uses of argatroban
Moledina et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Alternatives to unfractionated heparin for anticoagulation in cardiopulmonary bypass.
von Segesser et al. · Perfusion
Added to ASH registry: 2026-05-28
Anticoagulants and inhibitors of platelet aggregation derived from leeches
Salzet. · FEBS letters
Added to ASH registry: 2026-05-28
Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia
Lewis et al. · Circulation
Added to ASH registry: 2026-05-28
Argatroban for prevention and treatment of thromboembolism in heparin-induced thrombocytopenia.
Kondo LM et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Bivalirudin for percutaneous coronary intervention and in acute coronary syndromes
Bates ER · Current cardiology reports
Added to ASH registry: 2026-05-28
Delayed-type hypersensitivity and cross-reactivity to heparins and danaparoid: a prospective study
Grassegger et al. · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
Added to ASH registry: 2026-05-28
Direct thrombin antagonists
Lankes W et al. · Herz
Added to ASH registry: 2026-05-28
Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa.
Pinto et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Discovery of the factor Xa inhibitor, ZK 807834 (CI-1031)
Light et al. · Current topics in medicinal chemistry
Added to ASH registry: 2026-05-28
Drugs for the prevention and treatment of thrombosis in patients with heparin-induced thrombocytopenia
Lubenow N et al. · American journal of cardiovascular drugs : drugs, devices, and other interventions
Added to ASH registry: 2026-05-28
Effects of methanol on expression of an anticoagulant hirudin in recombinant Hansenula polymorpha
Kim et al. · Journal of industrial microbiology & biotechnology
Added to ASH registry: 2026-05-28
Errors-in-variables in joint population pharmacokinetic/pharmacodynamic modeling
Bennett et al. · Biometrics
Added to ASH registry: 2026-05-28
Fibrin-mediated plasminogen activation.
Nieuwenhuizen · Annals of the New York Academy of Sciences
Added to ASH registry: 2026-05-28
Heparin-coated cardiopulmonary bypass circuits: current status.
Hsu · Perfusion
Added to ASH registry: 2026-05-28
Lepirudin is a safe and effective anticoagulant for patients with heparin-associated antiplatelet antibodies
Mudaliar et al. · Journal of vascular surgery
Added to ASH registry: 2026-05-28
Management of Heparin-Induced Thrombocytopenia During Renal Replacement Therapy.
Davenport · Hemodialysis international. International Symposium on Home Hemodialysis
Added to ASH registry: 2026-05-28
Neutrophil enhancement of fibrin deposition under flow through platelet-dependent and -independent mechanisms
Goel et al. · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-28
New anticoagulants.
Hirsh · American heart journal
Added to ASH registry: 2026-05-28
Non-hemostatic activity of coagulation factor Xa: potential implications for various diseases
Leadley et al. · Current opinion in pharmacology
Added to ASH registry: 2026-05-28
Production and clinical development of a Hansenula polymorpha-derived PEGylated hirudin.
Avgerinos et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Prolonged in vivo anticoagulant activity of a hirudin-albumin fusion protein secreted from Pichia pastoris
Sheffield WP et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammation.
Esmon · Critical care medicine
Added to ASH registry: 2026-05-28
r-hirudin as anticoagulant for cardiopulmonary bypass
Cameron RJ · Anaesthesia and intensive care
Added to ASH registry: 2026-05-28
Standard heparin, low molecular weight heparin, low molecular weight heparinoid, and recombinant hirudin differ in their ability to inhibit transduction by recombinant adeno-associated virus type 2 vectors
Hacker et al. · Gene therapy
Added to ASH registry: 2026-05-28
Structure and biology of tissue factor pathway inhibitor.
Bajaj et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
The direct thrombin inhibitor melagatran and its oral prodrug H 376/95: intestinal absorption properties, biochemical and pharmacodynamic effects
Gustafsson D et al. · Thrombosis research
Added to ASH registry: 2026-05-28
The structure and biological features of fibrinogen and fibrin.
Mosesson et al. · Annals of the New York Academy of Sciences
Added to ASH registry: 2026-05-28
The tissue factor pathway in disseminated intravascular coagulation.
Østerud et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
The use of hirudin as universal anticoagulant in haematology, clinical chemistry and blood grouping
Menssen HD et al. · Clinical chemistry and laboratory medicine
Added to ASH registry: 2026-05-28
Tissue factor pathway inhibitor: an update of potential implications in the treatment of cardiovascular disorders.
Kaiser et al. · Expert opinion on investigational drugs
Added to ASH registry: 2026-05-28
Comparative trial of local pharmacotherapy with L-arginine, r-hirudin, and molsidomine to reduce restenosis after balloon angioplasty of stenotic rabbit iliac arteries
Kalinowski M · Radiology
Added to ASH registry: 2026-05-27
Cost effectiveness of desirudin compared with a low molecular weight heparin in the prevention of deep vein thrombosis after total hip replacement surgery
Levin LA et al. · PharmacoEconomics
Added to ASH registry: 2026-05-27
Diagnosis and therapy of laryngeal diseases in the history of medicine. I: The pre-laryngoscopic era
Feldmann H et al. · Laryngo- rhino- otologie
Added to ASH registry: 2026-05-27
Efficacy and safety of topical hirudin (Hirudex): a double-blind, placebo-controlled study
Stamenova PK et al. · European review for medical and pharmacological sciences
Added to ASH registry: 2026-05-27
Electrostatic steering and ionic tethering in the formation of thrombin-hirudin complexes: the role of the thrombin anion-binding exosite-I
Myles T et al. · Biochemistry
Added to ASH registry: 2026-05-27
Enhanced production of anticoagulant hirudin in recombinant Saccharomyces cerevisiae by chromosomal delta-integration
Kim MD et al. · J Biotechnol
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia: natural history, diagnosis, and management
Deitcher SR, Carman TL · Vascular medicine
Added to ASH registry: 2026-05-27
Neurite-stimulating effect of Hirudo medicinalis salivary gland secreting factors in organotypic culture of the dorsal root ganglia
Chalisova NI et al. · Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova
Added to ASH registry: 2026-05-27
Sequential assignment and secondary structure of saratin, an inhibitor of von Willebrand factor-dependent platelet adhesion to collagen
Maurer T et al. · J Biomol NMR
Added to ASH registry: 2026-05-27
Technical improvements in genetic manipulation of Pichia pastoris and their application in hirudin expression
Cai CQ et al. · Sheng Wu Gong Cheng Xue Bao
Added to ASH registry: 2026-05-27
The dual role of thrombin's anion-binding exosite-I in the recognition and cleavage of the protease-activated receptor 1
Myles T et al. · European journal of biochemistry
Added to ASH registry: 2026-05-27
The potential role of new therapies in deep-vein thrombosis prophylaxis
Wille-Jørgensen P · Semin Hematol
Added to ASH registry: 2026-05-27
Bivalirudin: a new approach to anticoagulation
Nawarskas JJ, Anderson JR · Heart disease (Hagerstown, Md.)
Added to ASH registry: 2026-05-26
Hirudo medicinalis: the medicinal leech
Andrews S · The Journal of audiovisual media in medicine
Added to ASH registry: 2026-05-26
Production and characterization of saratin, an inhibitor of von Willebrand factor-dependent platelet adhesion to collagen
Barnes CS, Krafft B, Frech M et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-26
Saratin, an inhibitor of von Willebrand factor-dependent platelet adhesion, decreases platelet aggregation and intimal hyperplasia in a rat carotid endarterectomy model
Cruz CP, Eidt J, Drouilhet J, Brown AT, Wang Y, Barnes CS, Moursi MM · Journal of vascular surgery
Added to ASH registry: 2026-05-26
Clinical monitoring of hirudin and direct thrombin inhibitors
Nowak G · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-03-18
Current status of the anticoagulant hirudin: its biotechnological production and clinical practice
Sohn J et al. · Applied microbiology and biotechnology
Added to ASH registry: 2026-03-18
Proteinase inhibitors from the medicinal leech Hirudo medicinalis
Baskova I, Zavalova L · Biochemistry. Biokhimiia
Added to ASH registry: 2026-03-18
Recombinant hirudin in clinical practice: focus on lepirudin
Greinacher A, Lubenow N · Circulation
Added to ASH registry: 2026-03-18
A quick assay for monitoring recombinant hirudin during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia type II : adaptation of the ecarin clotting time to the act II device
Koster et al. · The Journal of thoracic and cardiovascular surgery
Added to ASH registry: 2026-05-28
Antihirudin antibodies in patients with heparin-induced thrombocytopenia treated with lepirudin: incidence, effects on aPTT, and clinical relevance
Eichler et al. · Blood
Added to ASH registry: 2026-05-28
Bivalirudin for percutaneous coronary interventions: development perspective
Bittl · The Journal of invasive cardiology
Added to ASH registry: 2026-05-28
Bivalirudin in patients with heparin-induced thrombocytopenia undergoing percutaneous coronary intervention
Campbell KR et al. · The Journal of invasive cardiology
Added to ASH registry: 2026-05-28
Bivalirudin: a new generation antithrombotic drug
Scatena et al. · Expert opinion on investigational drugs
Added to ASH registry: 2026-05-28
Cardiopulmonary bypass in humans: bypassing unfractionated heparin.
Frederiksen · The Annals of thoracic surgery
Added to ASH registry: 2026-05-28
Cardiopulmonary bypass in patients with heparin-induced thrombocytopenia and thrombosis.
Follis et al. · The Annals of thoracic surgery
Added to ASH registry: 2026-05-28
Cerebral venous sinus thrombosis.
Allroggen et al. · Postgraduate medical journal
Added to ASH registry: 2026-05-28
Clinical application of argatroban as an alternative anticoagulant for extracorporeal circulation
Kawada et al. · Hematology/oncology clinics of North America
Added to ASH registry: 2026-05-28
Clinical experience of Argatroban for anticoagulation in cardiovascular surgery.
Ohteki et al. · The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi
Added to ASH registry: 2026-05-28
Combination reperfusion therapy with abciximab and reduced dose reteplase: results from TIMI 14. The Thrombolysis in Myocardial Infarction (TIMI) 14 Investigators.
Antman EM et al. · European heart journal
Added to ASH registry: 2026-05-28
Continuous haemofiltration with r-hirudin (lepirudin) as anticoagulant in a patient with heparin induced thrombocytopenia (HIT II)
Schneider T et al. · Wiener klinische Wochenschrift
Added to ASH registry: 2026-05-28
Current status of anticoagulants
Oger E et al. · Presse medicale (Paris, France : 1983)
Added to ASH registry: 2026-05-28
Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.
Slon-Usakiewicz et al. · Biochemistry
Added to ASH registry: 2026-05-28
Dosage, pharmacological effects and clinical outcomes for bivalirudin in percutaneous coronary intervention
Lui HK · The Journal of invasive cardiology
Added to ASH registry: 2026-05-28
Elimination of recombinant hirudin by modified ultrafiltration during simulated cardiopulmonary bypass: assessment of different filter systems
Koster et al. · Anesthesia and analgesia
Added to ASH registry: 2026-05-28
Fibrin specificity and procoagulant effect related to the kallikrein-contact phase system and to plasmin generation with double-bolus reteplase and front-loaded alteplase thrombolysis in acute myocardial infarction.
Hoffmeister HM et al. · The American journal of cardiology
Added to ASH registry: 2026-05-28
Heparin-binding exosite of factor Xa.
Rezaie · Trends in cardiovascular medicine
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia with thromboembolic complications: meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range.
Greinacher et al. · Blood
Added to ASH registry: 2026-05-28
Heparin-Induced thrombocytopenia: minimising the risks in the elderly patient
Tardy-Poncet et al. · Drugs & aging
Added to ASH registry: 2026-05-28
Hirudin as anticoagulant for cardiopulmonary bypass: importance of preoperative renal function
Koster A et al. · The Annals of thoracic surgery
Added to ASH registry: 2026-05-28
Lepirudin blunts endotoxin-induced coagulation activation
Pernerstorfer et al. · Blood
Added to ASH registry: 2026-05-28
Management of patients with heparin-induced thrombocytopenia: focus on recombinant hirudin
Lubenow N et al. · Journal of thrombosis and thrombolysis
Added to ASH registry: 2026-05-28
Novel, bedside, tissue factor-dependent clotting assay permits improved assessment of combination antithrombotic and antiplatelet therapy
Holmes et al. · Circulation
Added to ASH registry: 2026-05-28
Novel, potent and selective chimeric FXa inhibitors featuring hydrophobic P1-ketoamide moieties
Semple et al. · Bioorganic & medicinal chemistry letters
Added to ASH registry: 2026-05-28
Protease nexin II interactions with coagulation factor XIa are contained within the Kunitz protease inhibitor domain of protease nexin II and the factor XIa catalytic domain
Badellino et al. · Biochemistry
Added to ASH registry: 2026-05-28
SERPIN regulation of factor XIa. The novel observation that protease nexin 1 in the presence of heparin is a more potent inhibitor of factor XIa than C1 inhibitor
Knauer et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
The protein C pathway.
Esmon · Critical care medicine
Added to ASH registry: 2026-05-28
The role of bivalirudin in percutaneous coronary intervention
Topol EJ · The Journal of invasive cardiology
Added to ASH registry: 2026-05-28
The use of bivalirudin in patients with renal impairment
Robson et al. · The Journal of invasive cardiology
Added to ASH registry: 2026-05-28
Theromin, a novel leech thrombin inhibitor
Salzet et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Thrombolysis and percutaneous transluminal coronary angioplasty in patients with acute myocardial infarction.
Zeymer U et al. · Zeitschrift fur Kardiologie
Added to ASH registry: 2026-05-28
Activated neutrophils impair gastric cytoprotection role of neutrophil elastase
Harada N et al. · Digestive diseases and sciences
Added to ASH registry: 2026-05-27
Crystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor
Richardson JL et al. · The EMBO journal
Added to ASH registry: 2026-05-27
Desirudin: a review of its use in the management of thrombotic disorders
Matheson AJ et al. · Drugs
Added to ASH registry: 2026-05-27
Finding the right fit: effective thrombosis risk stratification in orthopedic patients
Arcelus JI et al. · Orthopedics
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia
Depasse F, Samama MM · Annales de biologie clinique
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia (review)
Fabris F et al. · Haematologica
Added to ASH registry: 2026-05-27
Heparin-induced thrombocytopenia: how to manage it, how to avoid it
Caiola E · Cleveland Clinic journal of medicine
Added to ASH registry: 2026-05-27
Hirudin reduces tissue factor expression and attenuates graft arteriosclerosis in rat cardiac allografts
Holschermann H et al. · Circulation
Added to ASH registry: 2026-05-27
Hirudin-based anticoagulant strategies for patients with suspected heparin-induced thrombocytopenia undergoing percutaneous coronary interventions and bypass grafting
Becker RC · Journal of Thrombosis and Thrombolysis
Added to ASH registry: 2026-05-27
Inhibition of induced and spontaneous platelet aggregation by destabilase from medicinal leech
Baskova I et al. · Platelets
Added to ASH registry: 2026-05-27
Lepirudin dosing in dialysis-dependent renal failure
Wittkowsky AK et al. · Pharmacotherapy
Added to ASH registry: 2026-05-27
Modulation of clearance of recombinant serum albumin by either glycosylation or truncation
Sheffield WP et al. · Thrombosis research
Added to ASH registry: 2026-05-27
New therapeutic options in deep vein thrombosis prophylaxis
Eriksson BI et al. · Seminars in hematology
Added to ASH registry: 2026-05-27
New therapeutic options in DVT prophylaxis
Wille-Jorgensen P et al. · Orthopedics
Added to ASH registry: 2026-05-27
Novel inhibitors of factor X for use in cardiovascular diseases
Spencer FA et al. · Current cardiology reports
Added to ASH registry: 2026-05-27
PAR3 is a cofactor for PAR4 activation by thrombin
Nakanishi-Matsui M et al. · Nature
Added to ASH registry: 2026-05-27
Pathophysiology and therapeutic modification of thrombin generation in patients with coronary artery disease
Pothula A et al. · European Journal of Pharmacology
Added to ASH registry: 2026-05-27
Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin
Shapiro MJ et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-27
Recombinant decorsin: dynamics of the RGD recognition site
Krezel AM et al. · Protein science : a publication of the Protein Society
Added to ASH registry: 2026-05-27
The pharmacokinetics and pharmacodynamics of argatroban: effects of age, gender, and hepatic or renal dysfunction
Swan SK, Hursting MJ · Pharmacotherapy
Added to ASH registry: 2026-05-27
The role of Glu(192) in the allosteric control of the S(2)' and S(3)' subsites of thrombin
Marque PE et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-27
The stabilization and release of hirudin from liposomes or lipid-assemblies coated with hydrophobically modified dextran
Mumper RJ et al. · AAPS PharmSciTech
Added to ASH registry: 2026-05-27
Use of direct thrombin inhibitors in acute coronary syndrome
Nemergut C et al. · Clinical therapeutics
Added to ASH registry: 2026-05-27
Clinical and scientific considerations in leech therapy for the management of acute venous congestion: an updated review
Weinfeld AB et al. · Annals of plastic surgery
Added to ASH registry: 2026-05-26
[Peptides as inhibitors of thrombin coagulation activity and of thrombocyte aggregation].
Pastorova VE et al. · Uspekhi fiziologicheskikh nauk
Added to ASH registry: 2026-05-28
Activation of the contact system of coagulation does not contribute to the hemostatic imbalance in hypertriglyceridemia
Minnema et al. · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-28
Allosteric modulation of BPTI interaction with human alpha- and zeta-thrombin.
De Cristofaro et al. · European journal of biochemistry
Added to ASH registry: 2026-05-28
Anticoagulant therapy in unstable angina
Choy JB et al. · Cardiology clinics
Added to ASH registry: 2026-05-28
Anticoagulation and anticoagulation reversal with cardiac surgery involving cardiopulmonary bypass: an update.
Despotis et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-28
Current clinical use of reteplase for thrombolysis. A pharmacokinetic-pharmacodynamic perspective.
Martin U et al. · Clinical pharmacokinetics
Added to ASH registry: 2026-05-28
Effectiveness of early coronary angioplasty and abciximab for failed thrombolysis (reteplase or alteplase) during acute myocardial infarction (results from the GUSTO-III trial). Global Use of Strategies To Open occluded coronary arteries.
Miller JM et al. · The American journal of cardiology
Added to ASH registry: 2026-05-28
Lepirudin (recombinant hirudin) for parenteral anticoagulation in patients with heparin-induced thrombocytopenia. Heparin-Associated Thrombocytopenia Study (HAT) investigators.
Greinacher et al. · Circulation
Added to ASH registry: 2026-05-28
Recombinant hirudin (lepirudin) as anticoagulant in intensive care patients treated with continuous hemodialysis
Fischer KG et al. · Kidney international. Supplement
Added to ASH registry: 2026-05-28
Recombinant hirudin (lepirudin) for the improvement of thrombolysis with streptokinase in patients with acute myocardial infarction: results of the HIT-4 trial
Neuhaus et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
Recombinant hirudin (lepirudin) provides safe and effective anticoagulation in patients with heparin-induced thrombocytopenia: a prospective study.
Greinacher et al. · Circulation
Added to ASH registry: 2026-05-28
Sites of elimination and pharmacokinetics of recombinant [131I]lepirudin in baboons
Meiring et al. · Journal of pharmaceutical sciences
Added to ASH registry: 2026-05-28
Tissue factor pathway inhibitor.
Camici et al. · Minerva medica
Added to ASH registry: 2026-05-28
Biochemical characterization of a thrombin inhibitor from the bloodsucking bug Dipetalogaster maximus
Lange U et al. · Haemostasis
Added to ASH registry: 2026-05-27
Bloodletting as medical therapy for 2500 years
Ulvik RJ et al. · Tidsskrift for den Norske laegeforening
Added to ASH registry: 2026-05-27
Enhancement of heparin cofactor II anticoagulant activity
Bauman SJ et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-27
Evidence that heparin but not hirudin reduces PAI-1 expression in cultured human endothelial cells
Orbe J et al. · Thrombosis research
Added to ASH registry: 2026-05-27
Functional phage display of leech-derived tryptase inhibitor (LDTI): construction of a library and selection of thrombin inhibitors
Tanaka AS et al. · FEBS letters
Added to ASH registry: 2026-05-27
Future prospects of prophylaxis for deep vein thrombosis
Pini M · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-27
Hyaluronidase activity in leeches (Hirudinea)
Hovingh P et al. · Comp Biochem Physiol B Biochem Mol Biol
Added to ASH registry: 2026-05-27
Implications of the Organization to Assess Strategies for Ischemic Syndromes-2 (OASIS-2) study and the results in the context of other trials
Fox KA et al. · The American journal of cardiology
Added to ASH registry: 2026-05-27
Incorporation of noncoded amino acids into the N-terminal domain 1-47 of hirudin yields a highly potent and selective thrombin inhibitor
De Filippis V et al. · Protein science : a publication of the Protein Society
Added to ASH registry: 2026-05-27
Invertebrate compounds acting on the hemostatic mechanism
Arocha-Pinango CL et al. · Blood Coagul Fibrinolysis
Added to ASH registry: 2026-05-27
Probing intermolecular backbone H-bonding in serine proteinase-protein inhibitor complexes
Lu W et al. · Chemistry & biology
Added to ASH registry: 2026-05-27
Roles of oxygen radicals and elastase in citric acid-induced airway constriction of guinea-pigs
Lai YL et al. · British journal of pharmacology
Added to ASH registry: 2026-05-27
The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors
Uson I et al. · Structure
Added to ASH registry: 2026-05-27
The collagen-binding leech products rLAPP and calin prevent both von Willebrand factor and alpha2beta1(GPIa/IIa)-I-domain binding to collagen in a different manner
Depraetere H et al. · Thromb Haemost
Added to ASH registry: 2026-05-27
The crystal structure of alpha-thrombin-hirunorm IV complex reveals a novel specificity site recognition mode
Lombardi A et al. · Protein science : a publication of the Protein Society
Added to ASH registry: 2026-05-27
The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop
Dekker RJ et al. · Journal of molecular biology
Added to ASH registry: 2026-05-27
Anticoagulants in acute coronary syndromes
Turpie AG · The American journal of cardiology
Added to ASH registry: 2026-05-26
Cardiovascular drug highlight: hirudin
Cheng-Lai A · Heart disease (Hagerstown, Md.)
Added to ASH registry: 2026-03-18
Lepirudin: a review of its potential place in the management of thrombotic disorders
Adkins et al. · BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy
Added to ASH registry: 2026-05-29
Coagulation factor Xa: the prothrombinase complex as an emerging therapeutic target for small molecule inhibitors.
Scarborough · Journal of enzyme inhibition
Added to ASH registry: 2026-05-28
Fibrinogen structure and fibrin clot assembly.
Mosesson · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Lepirudin for heparin-induced thrombocytopenia.
Unknown · The Medical letter on drugs and therapeutics
Added to ASH registry: 2026-05-28
New treatment options for heparin-induced thrombocytopenia
Ortel et al. · Seminars in hematology
Added to ASH registry: 2026-05-28
Pharmacology and therapeutic applications of hirudin, a new anticoagulant
Glusa et al. · Kidney international. Supplement
Added to ASH registry: 2026-05-28
Sustained release of injectable zinc-recombinant hirudin suspensions: development and validation of in vitro release model
Gietz et al. · European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Added to ASH registry: 2026-05-28
Chemical synthesis and structural characterization of the RGD-protein decorsin: a potent inhibitor of platelet aggregation
Polverino de Laureto P et al. · Protein science : a publication of the Protein Society
Added to ASH registry: 2026-05-27
Economic evaluation of desirudin vs heparin in deep vein thrombosis prevention after hip replacement surgery
Levin LA et al. · Pharmacoeconomics
Added to ASH registry: 2026-05-27
Elastase in hyperpnea-induced guinea pig airway constriction
Lai YL · European journal of pharmacology
Added to ASH registry: 2026-05-27
Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex
De Simone G et al. · Protein science : a publication of the Protein Society
Added to ASH registry: 2026-05-27
ICAM-1-CD18 interaction mediates neutrophil cytotoxicity through protease release
Barnett CC · The American journal of physiology
Added to ASH registry: 2026-05-27
Leeches in medicine
Thearle MJ et al. · Australian and New Zealand journal of surgery
Added to ASH registry: 2026-05-27
Polymorphonuclear leukocytes induce PDGF release from IL-1beta-treated endothelial cells: role of adhesion molecules and serine proteases
Totani L · Arteriosclerosis, thrombosis, and vascular biology
Added to ASH registry: 2026-05-27
Prolonged thrombin inhibition reduces restenosis after balloon angioplasty in porcine coronary arteries
Gallo R · Circulation
Added to ASH registry: 2026-05-27
Role of neutrophil elastase in compression-induced spinal cord injury in rats
Taoka Y · Brain research
Added to ASH registry: 2026-05-27
Staging of middle and late embryonic development in the medicinal leech Hirudo medicinalis
Reynolds SA et al. · Journal of comparative neurology
Added to ASH registry: 2026-05-27
Stopped flow fluorescence energy transfer measurement of the rate constants describing the reversible formation and the irreversible rearrangement of the elastase-alpha1-proteinase inhibitor complex
Mellet P · The Journal of biological chemistry
Added to ASH registry: 2026-05-27
A soluble tissue factor mutant is a selective anticoagulant and antithrombotic agent.
Kelley et al. · Blood
Added to ASH registry: 2026-05-28
Anticoagulation with Novastan (argatroban) in patients with heparin-induced thrombocytopenia and heparin-induced thrombocytopenia and thrombosis syndrome
Lewis et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Application of argatroban, direct thrombin inhibitor, in heparin-intolerant patients requiring extracorporeal circulation
Matsuo et al. · Artificial organs
Added to ASH registry: 2026-05-28
Congenital dysfibrinogenemia.
Martinez · Current opinion in hematology
Added to ASH registry: 2026-05-28
Critical role of W60d in thrombin allostery.
Guinto et al. · Biophysical chemistry
Added to ASH registry: 2026-05-28
Development of argatroban, a direct thrombin inhibitor, and its clinical application
Matsuo et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Effect of argatroban, a selective thrombin inhibitor, on animal models of cerebral thrombosis
Tamao et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Effect of renal impairment on the pharmacokinetics and pharmacodynamics of desirudin
Lefvre et al. · Clinical pharmacology and therapeutics
Added to ASH registry: 2026-05-28
Factor XIIa activation of plasminogen is enhanced by contact activating surfaces and Zn2+
Schousboe et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Functional characterization of recombinant human meizothrombin and Meizothrombin(desF1). Thrombomodulin-dependent activation of protein C and thrombin-activatable fibrinolysis inhibitor (TAFI), platelet aggregation, antithrombin-III inhibition.
Côté et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia. Pathogenesis, frequency, avoidance and management.
Warkentin · Drug safety
Added to ASH registry: 2026-05-28
Kinetic pathway for the slow to fast transition of thrombin. Evidence of linked ligand binding at structurally distinct domains.
Lai et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Molecular mechanisms of thrombin function.
Di Cera et al. · Cellular and molecular life sciences : CMLS
Added to ASH registry: 2026-05-28
Monitoring of recombinant hirudin: assessment of a plasma-based ecarin clotting time assay
Pötzsch et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Nonpeptide glycoprotein IIb/IIIa inhibitors. 15. Antithrombotic efficacy of L-738,167, a long-acting GPIIb/IIIa antagonist, correlates with inhibition of adenosine diphosphate-induced platelet aggregation but not with bleeding time prolongation
Cook et al. · The Journal of pharmacology and experimental therapeutics
Added to ASH registry: 2026-05-28
Pharmacodynamic and safety results of PEG-Hirudin in healthy volunteers
Esslinger et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Pharmacokinetics of recombinant hirudin in hemodialyzed end-stage renal failure patients
Vanholder et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Potent antithrombin activity and delayed clearance from the circulation characterize recombinant hirudin genetically fused to albumin
Syed et al. · Blood
Added to ASH registry: 2026-05-28
Rational engineering of activity and specificity in a serine protease.
Dang et al. · Nature biotechnology
Added to ASH registry: 2026-05-28
Recombinant hirudin as an anticoagulant during cardiac operations: experiments in a pig model
Riess et al. · European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Added to ASH registry: 2026-05-28
Recombinant hirudin is a heparin alternative in cardiac surgery
Riess et al. · Journal of cardiothoracic and vascular anesthesia
Added to ASH registry: 2026-05-28
Recombinant hirudin prevents postoperative fibrin formation after experimental cataract surgery
Mittra et al. · Ophthalmology
Added to ASH registry: 2026-05-28
Reduction of plasma clot stability by a novel factor XIIIa inhibitor from the Giant Amazon Leech, Haementeria ghilianii
Wallis et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Stable expression and purification of a secreted human recombinant prethrombin-2 and its activation to thrombin.
Russo et al. · Protein expression and purification
Added to ASH registry: 2026-05-28
Strategies for development of novel antithrombotics: modulating thrombin's procoagulant and anticoagulant properties.
Hall et al. · Cellular and molecular life sciences : CMLS
Added to ASH registry: 2026-05-28
The therapeutic potential of novel anticoagulants
Chi et al. · Expert opinion on investigational drugs
Added to ASH registry: 2026-05-28
A comparison of recombinant hirudin with a low-molecular-weight heparin to prevent thromboembolic complications after total hip replacement
Eriksson BI et al. · N Engl J Med
Added to ASH registry: 2026-05-27
Anticoagulation with r-hirudin in regular haemodialysis with heparin-induced thrombocytopenia (HIT II)
Nowak G · Wiener klinische Wochenschrift
Added to ASH registry: 2026-05-27
Comparison of enoxaparin, hirulog, and heparin as adjunctive antithrombotic therapy during thrombolysis with rtPA in the stenosed canine coronary artery
Leadley RJ et al. · Thrombosis and Haemostasis
Added to ASH registry: 2026-05-27
Hyaluronidases in tissue invasion
Csoka TB et al. · Invasion Metastasis
Added to ASH registry: 2026-05-27
Intimal hyperplasia following vascular injury is not inhibited by an antisense thrombin receptor oligodeoxynucleotide
Herbert JM et al. · Journal of cellular physiology
Added to ASH registry: 2026-05-27
Pharmacologic prevention of acute ischemic complications of coronary angioplasty
Wheeldon N · Catheterization and cardiovascular diagnosis
Added to ASH registry: 2026-05-27
Prevention of thromboembolism with use of recombinant hirudin. Results of a double-blind, multicenter trial comparing the efficacy of desirudin (Revasc) with that of unfractionated heparin in patients having a total hip replacement
Eriksson BI et al. · J Bone Joint Surg Am
Added to ASH registry: 2026-05-27
The crystal structure of human alpha-thrombin complexed with LY178550, a nonpeptidyl, active site-directed inhibitor
Chirgadze NY et al. · Protein science : a publication of the Protein Society
Added to ASH registry: 2026-05-27
The regulation of p42/p44 mitogen-activated protein kinases in the injured rat carotid artery
Lille ST et al. · Journal of surgical research
Added to ASH registry: 2026-05-27
X-ray structure of antistasin at 1.9 A resolution and its modelled complex with blood coagulation factor Xa
Lapatto R et al. · EMBO Journal
Added to ASH registry: 2026-05-27
A case report on the use of recombinant hirudin as an anticoagulant for cardiopulmonary bypass in open heart surgery
Riess et al. · European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Added to ASH registry: 2026-05-28
Argatroban: a synthetic thrombin inhibitor of low relative molecular mass
Fitzgerald et al. · Coronary artery disease
Added to ASH registry: 2026-05-28
Clearance of human factor XIa-inhibitor complexes in rats
Wuillemin et al. · British journal of haematology
Added to ASH registry: 2026-05-28
DDAVP reduces bleeding during continued hirudin administration in the rabbit
Bove CM et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Hirulog: a direct thrombin inhibitor for management of acute coronary syndromes
Maraganore et al. · Coronary artery disease
Added to ASH registry: 2026-05-28
Influence of recombinant hirudin on tissue-factor-induced activation of coagulation in rabbits
Kouz et al. · Haemostasis
Added to ASH registry: 2026-05-28
Production and purification of recombinant hirudin expressed in the methylotrophic yeast Pichia pastoris
Rosenfeld et al. · Protein expression and purification
Added to ASH registry: 2026-05-28
Recombinant hirudin as a periprocedural antithrombotic in coronary angioplasty for unstable angina pectoris
Hafner et al. · European heart journal
Added to ASH registry: 2026-05-28
Salivary lipid profiles of the leech (Hirudo medicinalis).
Rabinowitz · Lipids
Added to ASH registry: 2026-05-28
The role of the insertion loop around tryptophan 148 in tthe activity of thrombin.
DiBella et al. · Biochemistry
Added to ASH registry: 2026-05-28
Anticoagulation after intracoronary stent implantation
Bode C · Herz
Added to ASH registry: 2026-05-27
Enhancement of recombinant tissue-type plasminogen activator thrombolysis with a selective factor Xa inhibitor derived from the leech Hirudo medicinalis: comparison with heparin and hirudin in a rabbit thrombosis model
Kornowski R et al. · Coronary artery disease
Added to ASH registry: 2026-05-27
Failure of thrombin inhibition to prevent intracoronary thrombosis in the dog (Folts model)
Belcher PR et al. · Clinical Science
Added to ASH registry: 2026-05-27
Genes from the medicinal leech Hirudo medicinalis coding for unusual enzymes that specifically cleave endo-epsilon (gamma-Glu)-Lys isopeptide bonds and help to dissolve blood clots
Zavalova LL et al. · Molecular & general genetics
Added to ASH registry: 2026-05-27
Is colour Doppler ultrasound a sensitive screening method in diagnosing deep vein thrombosis after hip surgery?
Magnusson M et al. · Thromb Haemost
Added to ASH registry: 2026-05-27
Prevention of deep-vein thrombosis after total hip replacement: direct thrombin inhibition with recombinant hirudin, CGP 39393
Eriksson BI et al. · Lancet
Added to ASH registry: 2026-05-27
Selective inhibition of factor Xa during thrombolytic therapy markedly improves coronary artery patency in a canine model of coronary thrombosis
Nicolini FA et al. · Blood Coagulation and Fibrinolysis
Added to ASH registry: 2026-05-27
Synthesis, structure, and structure-activity relationships of divalent thrombin inhibitors containing an alpha-keto-amide transition-state mimetic
Krishnan R et al. · Protein science
Added to ASH registry: 2026-05-27
The ornithodorin-thrombin crystal structure, a key to the TAP enigma?
van de Locht A et al. · The EMBO journal
Added to ASH registry: 2026-05-27
Pharmacological properties of hirudin and its derivatives. Potential clinical advantages over heparin
Monreal M, Costa J, Salva P · Drugs & aging
Added to ASH registry: 2026-03-18
A comparison between the use of recombinant hirudin and heparin during hemodialysis
van Wyk et al. · Kidney international
Added to ASH registry: 2026-05-28
Conversion of thrombin into an anticoagulant by protein engineering.
Gibbs et al. · Nature
Added to ASH registry: 2026-05-28
Core domain of hirudin from the leech Hirudinaria manillensis: chemical synthesis, purification, and characterization of a Trp3 analog of fragment 1-47.
De Filippis V et al. · Biochemistry
Added to ASH registry: 2026-05-28
Development of a novel recombinant serpin with potential antithrombotic properties.
Hopkins et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Hemostasis and atherosclerosis.
Warkentin · The Canadian journal of cardiology
Added to ASH registry: 2026-05-28
High-level secretion of hirudin by Hansenula polymorpha--authentic processing of three different preprohirudins.
Weydemann U et al. · Applied microbiology and biotechnology
Added to ASH registry: 2026-05-28
Plasmin-mediated activation of contact system in response to pharmacological thrombolysis
Ewald et al. · Circulation
Added to ASH registry: 2026-05-28
Recombinant hirudin (HBW 023): biological data of ten patients with severe venous thrombo-embolism
Bridey et al. · American journal of hematology
Added to ASH registry: 2026-05-28
The Na+ binding site of thrombin.
Di Cera et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Use of a direct thrombin inhibitor (argatroban) during pulse-spray thrombolysis in experimental thrombosis
Valji et al. · Journal of vascular and interventional radiology : JVIR
Added to ASH registry: 2026-05-28
Use of recombinant hirudin as antithrombotic treatment in patients with heparin-induced thrombocytopenia
Schiele et al. · American journal of hematology
Added to ASH registry: 2026-05-28
A comparison of hirudin with heparin in the prevention of restenosis after coronary angioplasty. Helvetica Investigators
Serruys PW · The New England journal of medicine
Added to ASH registry: 2026-05-27
A comparison of the effect of decorsin and two disintegrins, albolabrin and eristostatin, on platelet function
McLane MA et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Calin from Hirudo medicinalis, an inhibitor of platelet adhesion to collagen, prevents platelet-rich thrombosis in hamsters
Deckmyn H et al. · Blood
Added to ASH registry: 2026-05-27
Calin from Hirudo medicinalis, an inhibitor of von Willebrand factor binding to collagen under static and flow conditions
Harsfalvi J et al. · Blood
Added to ASH registry: 2026-05-27
Comparative pharmacology of site directed antithrombin agents. Implication in drug development
Callas DD et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Crystal structure of a peptidyl pyridinium methyl ketone inhibitor with thrombin
Rehse PH et al. · Biochemistry
Added to ASH registry: 2026-05-27
Crystal structure of human alpha-thrombin complexed with hirugen and p-amidinophenylpyruvate at 1.6 A resolution
Chen Z et al. · Archives of biochemistry and biophysics
Added to ASH registry: 2026-05-27
Evaluation of recombinant hirudin (CGP 39,393/TMREVASC) in the prevention of restenosis after percutaneous transluminal coronary angioplasty
Herrman JP · European heart journal
Added to ASH registry: 2026-05-27
Inhibition of arterial thrombus formation in two canine models: comparison of ancrod, r-hirudin, and Ro 43-8857 GPIIb/IIIa antagonist
Rubsamen K et al. · Thrombosis and Haemostasis
Added to ASH registry: 2026-05-27
Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin
van de Locht A et al. · The EMBO journal
Added to ASH registry: 2026-05-27
Antithrombotic effect of piyavit, a substance from the medicinal leech (Hirudo medicinalis), containing prostanoid and destabilase fractions
Baskova IP, Zavalova LL, Basanova AV, Aquejouf OM, Azougagh-Oualane F, Doutremepuich C · Biokhimiia
Added to ASH registry: 2026-05-26
Arterial antithrombotic effect of piyavit, the novel pharmacological preparation from the medicinal leech, and of its components, prostanoids and enzyme destabilase
Baskova IP, Aguejouf OM, Azougagh-Oualane F, Zavalova LL, Basanova AV, Doutremepuich C · Thrombosis research
Added to ASH registry: 2026-05-26
Hirudin and excess bleeding. Implications for future use
Zeymer U, Neuhaus K · Drug safety
Added to ASH registry: 2026-03-18
Hirudin and hirudin analogues as new anticoagulant agents
Pineo G, Hull R · Current opinion in hematology
Added to ASH registry: 2026-03-18
A pilot study of subcutaneous recombinant hirudin (HBW 023) in the treatment of deep vein thrombosis
Schiele et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Ecotin is a potent anticoagulant and reversible tight-binding inhibitor of factor Xa
Seymour et al. · Biochemistry
Added to ASH registry: 2026-05-28
Epitope mapping of human factor IX inhibitor antibodies
Takahashi et al. · British journal of haematology
Added to ASH registry: 2026-05-28
Fibrin-targeted recombinant hirudin inhibits fibrin deposition on experimental clots more efficiently than recombinant hirudin
Bode et al. · Circulation
Added to ASH registry: 2026-05-28
Fibrinogen structure, activation, polymerization and fibrin gel structure.
Blombäck · Thrombosis research
Added to ASH registry: 2026-05-28
The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
Vijayalakshmi et al. · Protein science : a publication of the Protein Society
Added to ASH registry: 2026-05-28
Thrombolytic and antithrombotic efficacy of the platelet GPIIb-IIIa antagonist DMP728
Mousa et al. · Coronary artery disease
Added to ASH registry: 2026-05-28
A Kazal-type inhibitor of human mast cell tryptase: isolation from the medical leech Hirudo medicinalis, characterization, and sequence analysis
Sommerhoff CP et al. · Biol Chem Hoppe Seyler
Added to ASH registry: 2026-05-27
Current trends in the development of anticoagulant and antithrombotic drugs
Fareed J · The Medical clinics of North America
Added to ASH registry: 2026-05-27
Design of potent bivalent thrombin inhibitors based on hirudin sequence: incorporation of nonsubstrate-type active site inhibitors
Tsuda Y et al. · Biochemistry
Added to ASH registry: 2026-05-27
Direct thrombin inhibition with Rec-hirudin CGP 39393 as prophylaxis of thromboembolic complications after total hip replacement
Eriksson BI et al. · Thromb Haemost
Added to ASH registry: 2026-05-27
Displacement of fibrin-bound thrombin by r-hirudin precludes the use of 131I-r-hirudin for detecting pulmonary emboli in the rabbit
Rubens FD et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Expression and kinetic characterization of barley chymotrypsin inhibitors 1a and 1b
Greagg MA et al. · Biochim Biophys Acta
Added to ASH registry: 2026-05-27
Inhibition of in vitro clot growth by r-hirudin is more effective and longer sustained than by an analogous peptide
Romisch J et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Mutational analysis of antistasin, an inhibitor of blood coagulation factor Xa derived from the Mexican leech Haementeria officinalis
Theunissen HJ et al. · Thrombosis research
Added to ASH registry: 2026-05-27
New N alpha-guanidinobenzoyl derivatives of hirudin-54-65 containing stabilized carboxyl or phosphoryl groups on the side chain of phenylalanine-63
Thurieau C et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-27
Prevention of rethrombosis after coronary thrombolysis in a chronic canine model. II. Adjunctive therapy with r-hirudin
Rote WE et al. · Journal of Cardiovascular Pharmacology
Added to ASH registry: 2026-05-27
Radiolabeled r-hirudin as a measure of thrombin activity at or within the rabbit aorta wall in vitro and in vivo
Hatton MW et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Specific factor Xa inhibition reduces restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits
Ragosta M et al. · Circulation
Added to ASH registry: 2026-05-27
Thrombin generation following arterial injury is a critical initiating event in the pathogenesis of the proliferative stages of the atherosclerotic process
Walters TK et al. · Journal of vascular research
Added to ASH registry: 2026-05-27
True and artificial leeches and their use in otology
Feldmann H et al. · Laryngo- rhino- otologie
Added to ASH registry: 2026-05-27
Hirudin: clinical potential of a thrombin inhibitor
Johnson P · Annual review of medicine
Added to ASH registry: 2026-03-18
Hirudin: long live the leech!
Bhatt A · The Journal of the Association of Physicians of India
Added to ASH registry: 2026-03-18
Biologic effects of recombinant hirudin (CGP 39393) in human volunteers. European Hirudin in Thrombosis Group
Verstraete et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
Bovine factor XIIa inhibitor
Muldbjerg et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Novel hirudin variants from the leech Hirudinaria manillensis. Amino acid sequence, cDNA cloning and genomic organization.
Scacheri E et al. · European journal of biochemistry
Added to ASH registry: 2026-05-28
Structures of thrombin complexes with a designed and a natural exosite peptide inhibitor.
Qiu X et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
The antithrombotic and anticoagulant effects of a synthetic tripeptide and recombinant hirudin in various animal models
Bacher et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Vascular complications of vascularized composite tissue transfer: outcome and salvage techniques.
Yajima et al. · Microsurgery
Added to ASH registry: 2026-05-28
A new rat model of arterial thrombosis with a platelet-rich head and an erythrocyte-rich tail: thrombolysis experiments with specific thrombin inhibition
Lenfors S et al. · Blood Coagulation and Fibrinolysis
Added to ASH registry: 2026-05-27
Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms
Priestle JP et al. · Protein science : a publication of the Protein Society
Added to ASH registry: 2026-05-27
Crystallization and preliminary crystallographic analysis of antistasin, a leech-derived inhibitor of blood coagulation factor Xa
Schreuder H et al. · Journal of molecular biology
Added to ASH registry: 2026-05-27
Expression, purification and characterization of multigram amounts of a recombinant hybrid HV1-HV2 hirudin variant expressed in Saccharomyces cerevisiae
Lehman ED et al. · Protein expression and purification
Added to ASH registry: 2026-05-27
Recombinant hirudin in patients with chronic, stable coronary artery disease. Safety, half-life, and effect on coagulation parameters
Zoldhelyi P et al. · Circulation
Added to ASH registry: 2026-05-27
The structure of a designed peptidomimetic inhibitor complex of alpha-thrombin
Wu TP et al. · Protein engineering
Added to ASH registry: 2026-05-27
Hirudin: the famous anticoagulant agent
Markwardt F · Advances in experimental medicine and biology
Added to ASH registry: 2026-03-18
A low molecular weight platelet inhibitor of factor XIa: purification, characterization, and possible role in blood coagulation
Cronlund et al. · Biochemistry
Added to ASH registry: 2026-05-28
Anticoagulant efficacy and immunogenicity of the selective factor Xa inhibitor antistasin following subcutaneous administration in the rhesus monkey.
Dunwiddie CT et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Clinical application of the synthetic thrombin inhibitor, argatroban (MD-805)
Matsuo et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Direct thrombin inhibitors
Maffrand JP · Nouvelle revue francaise d'hematologie
Added to ASH registry: 2026-05-28
Hirudins: antithrombin anticoagulants
Stringer et al. · The Annals of pharmacotherapy
Added to ASH registry: 2026-05-28
Interaction of the N-terminal region of hirudin with the active-site cleft of thrombin.
Betz A et al. · Biochemistry
Added to ASH registry: 2026-05-28
Interaction of thrombin des-ETW with antithrombin III, the Kunitz inhibitors, thrombomodulin and protein C. Structural link between the autolysis loop and the Tyr-Pro-Pro-Trp insertion of thrombin.
Le Bonniec et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Primary structure and function of novel O-glycosylated hirudins from the leech Hirudinaria manillensis.
Steiner V et al. · Biochemistry
Added to ASH registry: 2026-05-28
Selective factor Xa inhibition by recombinant antistasin prevents vascular graft thrombosis in baboons.
Schaffer LW et al. · Arteriosclerosis and thrombosis : a journal of vascular biology
Added to ASH registry: 2026-05-28
Therapeutic levels of recombinant hirudin
Nowak et al. · Haemostasis
Added to ASH registry: 2026-05-28
Acceleration of recombinant tissue-type plasminogen activator-induced reperfusion and prevention of reocclusion by recombinant antistasin, a selective factor Xa inhibitor, in a canine model of femoral arterial thrombosis
Mellott MJ et al. · Circulation research
Added to ASH registry: 2026-05-27
Analysis of recombinant proteins by isoelectric focusing in immobilized pH gradients
Bischoff R et al. · Electrophoresis
Added to ASH registry: 2026-05-27
Combination of inhibition of thrombin and blockade of thromboxane A2 synthetase and receptors enhances thrombolysis and delays reocclusion in canine coronary arteries
Yao SK et al. · Circulation
Added to ASH registry: 2026-05-27
Conformationally restricted thrombin inhibitors resistant to proteolytic digestion
Szewczuk Z et al. · Biochemistry
Added to ASH registry: 2026-05-27
The hydrolysis and resynthesis of a single reactive site peptide bond in recombinant antistasin by coagulation factor Xa
Dunwiddie CT et al. · Archives of biochemistry and biophysics
Added to ASH registry: 2026-05-27
The pharmacology of extinction
Huxtable RJ · Journal of ethnopharmacology
Added to ASH registry: 2026-05-27
[Hirudin and hirudin fragments]
Deschamps A, Samama M · Annales de cardiologie et d'angeiologie
Added to ASH registry: 2026-03-18
[Hirudin--comeback of Hirudo medicinalis]
Lassila R · Duodecim; laaketieteellinen aikakauskirja
Added to ASH registry: 2026-03-18
[Physicians and leeches--and traces in words].
Naess K · Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke
Added to ASH registry: 2026-05-28
Allergy to protamine.
Weiss et al. · Clinical reviews in allergy
Added to ASH registry: 2026-05-28
Anticoagulant and antithrombotic actions of recombinant hirudin
Kaiser et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Characterization, stability and refolding of recombinant hirudin
Otto et al. · European journal of biochemistry
Added to ASH registry: 2026-05-28
Chemical modifications and amino acid substitutions in recombinant hirudin that increase hirudin-thrombin affinity
Winant et al. · Biochemistry
Added to ASH registry: 2026-05-28
Comparison of in vitro platelet aggregation and its inhibition by three antithrombotic drugs between human and guinea pig
Huang et al. · Proceedings of the National Science Council, Republic of China. Part B, Life sciences
Added to ASH registry: 2026-05-28
Hirudin and derivatives as anticoagulant agents
Markwardt F · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Hirudin and platelets.
Glusa E · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Hirudin as anticoagulant in experimental hemodialysis
Markwardt F et al. · Haemostasis
Added to ASH registry: 2026-05-28
Hirudin. A new and promising anticoagulant from leech
Aiach M et al. · La Revue du praticien
Added to ASH registry: 2026-05-28
Inherited bleeding disorders.
Blanchette et al. · Bailliere's clinical haematology
Added to ASH registry: 2026-05-28
Isolation of thrombin inhibitor from the leech Hirudinaria manillensis.
Electricwala A et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Laboratory assays for the evaluation of recombinant hirudin
Walenga JM et al. · Haemostasis
Added to ASH registry: 2026-05-28
Neutralization of recombinant hirudin: some practical considerations
Fareed et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Old and new natural products as the source of modern antithrombotic drugs
Beretz A et al. · Planta medica
Added to ASH registry: 2026-05-28
Old and new natural products as the source of modern antithrombotic drugs
Beretz A et al. · Planta medica
Added to ASH registry: 2026-05-28
Platelet aggregation in recombinant-hirudin-anticoagulated blood
Glusa et al. · Haemostasis
Added to ASH registry: 2026-05-28
Production of the HV1 variant of hirudin by recombinant DNA methodology
de et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
Recombinant hirudin: a new prospect in thrombosis
Talbot et al. · Current studies in hematology and blood transfusion
Added to ASH registry: 2026-05-28
Structure-function relationships of the C-terminal functional domain of hirudin and its variants.
Krstenansky JL et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-05-28
The influence of infusions of 1-desamino-8-D-arginine vasopressin (DDAVP) in vivo on the anticoagulant effect of recombinant hirudin (CGP39393) in vitro
Ibbotson SH et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
Toxicology of hirudin.
Klöcking HP · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Calin--a platelet adhesion inhibitor from the saliva of the medicinal leech
Munro R et al. · Blood Coagul Fibrinolysis
Added to ASH registry: 2026-05-27
Different susceptibility of elastase inhibitors to inactivation by proteinases from Staphylococcus aureus and Pseudomonas aeruginosa
Sponer M et al. · Biol Chem Hoppe Seyler
Added to ASH registry: 2026-05-27
Different susceptibility of elastase inhibitors to inactivation by proteinases from Staphylococcus aureus and Pseudomonas aeruginosa
Sponer M et al. · Biological chemistry Hoppe-Seyler
Added to ASH registry: 2026-05-27
Hirulog peptides with scissile bond replacements resistant to thrombin cleavage
Kline T et al. · Biochemical and biophysical research communications
Added to ASH registry: 2026-05-27
Past, present and future of hirudin
Markwardt F et al. · Haemostasis
Added to ASH registry: 2026-05-27
Refined structure of the hirudin-thrombin complex
Rydel TJ et al. · Journal of molecular biology
Added to ASH registry: 2026-05-27
Structure-function and refolding studies of the thrombin-specific inhibitor hirudin
Johnson PH et al. · Haemostasis
Added to ASH registry: 2026-05-27
Studies on the anticoagulant, antimetastatic and heparin-binding properties of ghilanten-related inhibitors
Brankamp RG et al. · Blood Coagul Fibrinolysis
Added to ASH registry: 2026-05-27
The use of medicinal leeches in microsurgery
Valauri FA et al. · Blood coagulation & fibrinolysis
Added to ASH registry: 2026-05-27
Destabilase, the novel epsilon-(gamma-Glu)-Lys isopeptidase with thrombolytic activity
Baskova IP, Nikonov GI · Blood coagulation & fibrinolysis
Added to ASH registry: 2026-05-26
Structure-activity relationships of recombinant hirudins
Stürzebecher J, Walsmann P · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-26
An objective perspective on recombinant hirudin: a new anticoagulant and antithrombotic agent
Fareed J et al. · Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Added to ASH registry: 2026-03-18
Clinical pharmacology of recombinant hirudin
Markwardt F, Nowak G, Stürzebecher J · Haemostasis
Added to ASH registry: 2026-03-18
Hirudin for diagnostic purposes
Stocker K · Haemostasis
Added to ASH registry: 2026-03-18
Hirudin, a new therapeutic tool?
Bichler J, Fritz H · Annals of hematology
Added to ASH registry: 2026-03-18
Isolation and characterization of hirudin from Hirudo medicinalis
Walsmann P · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-03-18
Methods for determination of hirudin
Stürzebecher J · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-03-18
Past, present and future of hirudin
Markwardt F · Haemostasis
Added to ASH registry: 2026-03-18
Pharmacokinetics of hirudin
Nowak G · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-03-18
Recombinant hirudin: genetic engineering and structure analysis
Märki W et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-03-18
Some objective considerations for the neutralization of the anticoagulant actions of recombinant hirudin
Fareed J et al. · Haemostasis
Added to ASH registry: 2026-03-18
The comeback of hirudin as an antithrombotic agent
Markwardt F · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-03-18
The history of leeching and hirudin
Fields W · Haemostasis
Added to ASH registry: 2026-03-18
Thrombin inhibition by hirudin: how hirudin inhibits thrombin
Fenton J et al. · Haemostasis
Added to ASH registry: 2026-03-18
Conversion of recombinant hirudin to the natural form by in vitro tyrosine sulfation. Differential substrate specificities of leech and bovine tyrosylprotein sulfotransferases
Niehrs et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Effect of recombinant hirudin, a specific inhibitor of thrombin, on endotoxin-induced intravascular coagulation and acute lung injury in pigs.
Hoffmann H et al. · The American review of respiratory disease
Added to ASH registry: 2026-05-28
Heparin and platelets
Warkentin et al. · Hematology/oncology clinics of North America
Added to ASH registry: 2026-05-28
Heparin-induced thrombocytopenia and arterial thrombosis: alternative therapies
Cola et al. · American heart journal
Added to ASH registry: 2026-05-28
Hirudin in haemodialysis
Bucha et al. · Thrombosis research
Added to ASH registry: 2026-05-28
Platelet functions in recombinant hirudin-anticoagulated blood
Glusa et al. · Haemostasis
Added to ASH registry: 2026-05-28
Preparation of monoclonal antibodies to hirudin and hirudin peptides. A method for studying the hirudin--thrombin interaction.
Schlaeppi JM et al. · European journal of biochemistry
Added to ASH registry: 2026-05-28
Production, properties, and thrombin inhibitory mechanism of hirudin amino-terminal core fragments.
Chang JY · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Quantitative comparison of recombinant hirudin's antithrombotic and anticoagulant activities with those of heparin
Porta et al. · Thrombosis research
Added to ASH registry: 2026-05-28
The anticoagulant mechanism of action of recombinant hirudin (CGP 39393) in plasma
Lindhout T et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-28
The COOH-terminal domain of hirudin. An exosite-directed competitive inhibitor of the action of alpha-thrombin on fibrinogen.
Naski MC et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
The structure of a complex of recombinant hirudin and human alpha-thrombin
Rydel et al. · Science (New York, N.Y.)
Added to ASH registry: 2026-05-28
von Willebrand's disease.
Perry JJ et al. · American family physician
Added to ASH registry: 2026-05-28
Antithrombotic effects of recombinant hirudin in experimental angioplasty and intravascular thrombolysis
Kaiser B et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition
Grtter MG et al. · The EMBO journal
Added to ASH registry: 2026-05-27
Decorsin. A potent glycoprotein IIb-IIIa antagonist and platelet aggregation inhibitor from the leech Macrobdella decora
Seymour JL et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-27
Interference of recombinant eglin C, a proteinase inhibitor extracted from leeches, with neutrophil-mediated platelet activation
Renesto P et al. · Laboratory investigation
Added to ASH registry: 2026-05-27
Preparation of dextran-bound recombinant hirudin and its pharmacokinetic behaviour
Markwardt F et al. · Biomedica biochimica acta
Added to ASH registry: 2026-05-27
[The medicinal leech Hirudo medicinalis: clinical use of the animal and therapeutic prospects of hirudin]
Henriot J et al. · Journal de pharmacie de Belgique
Added to ASH registry: 2026-03-18
Anticoagulant activity of synthetic hirudin peptides
Maraganore JM et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Biology of recombinant hirudin (CGP 39393): a new prospect in the treatment of thrombosis
Talbot et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Contribution of the N-terminal region of hirudin to its interaction with thrombin.
Wallace A et al. · Biochemistry
Added to ASH registry: 2026-05-28
Development of recombinant hirudin as a therapeutic anticoagulant and antithrombotic agent: some objective considerations
Walenga et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-28
Small cardioactive peptide-like immunoreactivity and its colocalization with FMRFamide-like immunoreactivity in the central nervous system of the leech Hirudo medicinalis
Evans BD et al. · Cell and tissue research
Added to ASH registry: 2026-05-28
C-terminal peptide alcohol, acid and amide analogs of desulfato hirudin54-65 as antithrombin agents
Krstenansky JL et al. · Thrombosis research
Added to ASH registry: 2026-05-27
Free radicals inactivate human neutrophil elastase and its inhibitors with comparable efficiency
Dean RT et al. · Biochemical and biophysical research communications
Added to ASH registry: 2026-05-27
Isolation and structural characterization of a potent inhibitor of coagulation factor Xa from the leech Haementeria ghilianii
Condra C et al. · Thrombosis and haemostasis
Added to ASH registry: 2026-05-27
Isolation of recombinant hirudin by preparative high-performance liquid chromatography
Bischoff R et al. · J Chromatogr
Added to ASH registry: 2026-05-27
The medicinal leech: historical perspectives
Adams SL · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-05-26
Development of hirudin as an antithrombotic agent
Markwardt F · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-03-18
Production and evaluation of recombinant hirudin
Courtney M et al. · Seminars in thrombosis and hemostasis
Added to ASH registry: 2026-03-18
Antithrombotic effect of preparations from the leeches Hirudo medicinalis
Nikonov GI et al. · Folia haematologica (Leipzig, Germany : 1928)
Added to ASH registry: 2026-05-28
Inactivation of human plasma kallikrein and factor XIa by protein C inhibitor
Meijers et al. · Biochemistry
Added to ASH registry: 2026-05-28
Inhibition of human blood coagulation factor XIa by C-1 inhibitor
Meijers et al. · Biochemistry
Added to ASH registry: 2026-05-28
Interaction of bovine factor XIIa with an inhibitor from bovine plasma
Thornton et al. · Biochimica et biophysica acta
Added to ASH registry: 2026-05-28
Pharmacokinetic studies with recombinant hirudin in dogs
Nowak et al. · Folia haematologica (Leipzig, Germany : 1928)
Added to ASH registry: 2026-05-28
Synthesis, platelet aggregation inhibitory activity, and in vivo antithrombotic activity of new 1,4-dihydropyridines
Sunkel et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-28
Antibiotic sensitivities of Aeromonas hydrophila cultured from medicinal leeches
Hermansdorfer J et al. · British journal of plastic surgery
Added to ASH registry: 2026-05-27
Evidence for the identity of hirudin isolated after kidney passage with the starting material
Henschen A et al. · Folia Haematol Int Mag Klin Morphol Blutforsch
Added to ASH registry: 2026-05-27
N-terminal requirements of small peptide anticoagulants based on hirudin54-65
Owen TJ et al. · Journal of medicinal chemistry
Added to ASH registry: 2026-05-27
The amino acid sequence of antistasin. A potent inhibitor of factor Xa reveals a repeated internal structure
Nutt E et al. · Journal of biological chemistry
Added to ASH registry: 2026-05-27
The comeback of hirudin--an old-established anticoagulant agent
Markwardt F et al. · Folia Haematol Int Mag Klin Morphol Blutforsch
Added to ASH registry: 2026-05-27
The medicinal leech: a page from the annelids of internal medicine
Adams SL · Annals of internal medicine
Added to ASH registry: 2026-05-26
[The leech or Hirudo medicinalis].
Zandbergen M · Tijdschrift voor ziekenverpleging
Added to ASH registry: 2026-05-28
Antithrombotic profile of iloprost in experimental models of in vivo platelet aggregation and thrombosis
Witt et al. · Advances in prostaglandin, thromboxane, and leukotriene research
Added to ASH registry: 2026-05-28
Isolation and characterization of an inhibitor of factor XIIa from bovine plasma
Thornton et al. · The Journal of biological chemistry
Added to ASH registry: 2026-05-28
Rapid purification and revised amino-terminal sequence of hirudin: a specific thrombin inhibitor of the bloodsucking leech.
Mao SJ et al. · Analytical biochemistry
Added to ASH registry: 2026-05-28
Regulation of factor XIa activity by platelets and alpha 1-protease inhibitor
Walsh et al. · The Journal of clinical investigation
Added to ASH registry: 2026-05-28
von Willebrand disease.
Zimmerman TS et al. · Human pathology
Added to ASH registry: 2026-05-28
Isolation and characterization of antistasin. An inhibitor of metastasis and coagulation
Tuszynski GP et al. · Journal of biological chemistry
Added to ASH registry: 2026-05-27
Ozone effects on inhibitors of human neutrophil proteinases
Smith CE et al. · Arch Biochem Biophys
Added to ASH registry: 2026-05-27
Ozone effects on inhibitors of human neutrophil proteinases
Smith CD et al. · Archives of biochemistry and biophysics
Added to ASH registry: 2026-05-27
Alpha-1-antitrypsin-Pittsburgh. A potent inhibitor of human plasma factor XIa, kallikrein, and factor XIIf
Scott et al. · The Journal of clinical investigation
Added to ASH registry: 2026-05-28
Disseminated intravascular coagulation.
Fruchtman et al. · Journal of the American College of Cardiology
Added to ASH registry: 2026-05-28
Inhibition of mast cell chymase by eglin c and antileukoprotease (HUSI-I). Indications for potential biological functions of these inhibitors
Fink et al. · Biological chemistry Hoppe-Seyler
Added to ASH registry: 2026-05-28
Equine pythiosis in Costa Rica: report of 39 cases
Mendoza L et al. · Mycopathologia
Added to ASH registry: 2026-05-27
Kinetics of the inhibition of thrombin by hirudin
Stone S, Hofsteenge J · Biochemistry
Added to ASH registry: 2026-03-18
[Destabilase: an enzyme of medicinal leech salivary gland secretion hydrolyzes the isopeptide bonds in stabilized fibrin].
Baskova et al. · Biokhimiia (Moscow, Russia)
Added to ASH registry: 2026-05-28
Alpha 1-antitrypsin-Pittsburgh: a potent inhibitor of human plasma factor XIa, kallikrein, and factor XIIf
Scott et al. · Transactions of the Association of American Physicians
Added to ASH registry: 2026-05-28
The hypercoagulable states.
Schafer · Annals of internal medicine
Added to ASH registry: 2026-05-28
On the isolation of the thrombin inhibitor hirudin
Walsmann P et al. · Thromb Res
Added to ASH registry: 2026-05-27
Pharmacology of hirudin: one hundred years after the first report of the anticoagulant agent in medicinal leeches
Markwardt F et al. · Biomed Biochim Acta
Added to ASH registry: 2026-05-27
Eglin c, a pharmacologically active elastase inhibitor
Schnebli HP, Seemüller U, Fritz H et al. · European journal of respiratory diseases. Supplement
Added to ASH registry: 2026-05-26
Eglin-c, a polypeptide derived from the medicinal leech, prevents human neutrophil elastase-induced emphysema and bronchial secretory cell metaplasia in the hamster
Snider GL, Stone PJ, Lucey EC et al. · The American review of respiratory disease
Added to ASH registry: 2026-05-26
Protein C.
Esmon · Progress in hemostasis and thrombosis
Added to ASH registry: 2026-05-28
Protease inhibitors in Haementeria leech species
Murer EH et al. · Thromb Haemost
Added to ASH registry: 2026-05-27
A large fragment approach to DNA synthesis: total synthesis of a gene for the protease inhibitor eglin c from the leech Hirudo medicinalis and its expression in E. coli
Rink H, Liersch M, Sieber P, Meyer F · Nucleic acids research
Added to ASH registry: 2026-05-26
Inactivation of factor XIa by plasma protease inhibitors: predominant role of alpha 1-protease inhibitor and protective effect of high molecular weight kininogen
Scott et al. · The Journal of clinical investigation
Added to ASH registry: 2026-05-28
Biochemical and pharmacological aspects of the thrombin inhibitor hirudin
Walsmann P et al. · Pharmazie
Added to ASH registry: 2026-05-27
Disseminated intravascular coagulation and related syndromes: etiology, pathophysiology, diagnosis, and management.
Bick · American journal of hematology
Added to ASH registry: 2026-05-28
A pathological and bacteriological study of the mammary glands of beef cows in north Queensland
Sobari TW et al. · Australian veterinary journal
Added to ASH registry: 2026-05-27
Proceedings: In vivo activity of tieclopidine, a new drug with platelet aggregation inhibiting, antisludge and antithrombotic properties
Ferrand et al. · Thrombosis et diathesis haemorrhagica
Added to ASH registry: 2026-05-28
The frequency of infertility in thoroughbred mares
Laing JA et al. · Journal of reproduction and fertility. Supplement
Added to ASH registry: 2026-05-27
Platelet aggregation and haemolysis induced in rats by intravenous infusion of ADP - effect of potentially antithrombotic drugs
Reyers-Degli et al. · Scandinavian journal of haematology
Added to ASH registry: 2026-05-28
Early Australian dental literature--prior to 1900
Levine S · Australian dental journal
Added to ASH registry: 2026-05-27
Letter: Incidence and prevalence
Leech FB · The Veterinary record
Added to ASH registry: 2026-05-27
Isolation of hirudin from medicinal leech
Markwardt F et al. · Pharmazie
Added to ASH registry: 2026-05-27
Purification and analysis of the thrombin inhibitor hirudin
Markwardt F et al. · Hoppe Seylers Z Physiol Chem
Added to ASH registry: 2026-05-27
The hyaluronidase of the leech: an endoglucuronidase
Linker A et al. · Nature
Added to ASH registry: 2026-05-27
Studies on the mechanism of the anticoagulant effect of hirudin
MARKWARDT F · Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie
Added to ASH registry: 2026-05-28