Американское общество гирудотерапии

Augmented blood removal after medicinal leech feeding in congested tissue flaps

Basic science / device development published in J Rehabil Res Dev (2002)

Последнее обновление: June 18, 2026Рецензент: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Preclinical (animal)Клинические исследованияConnor NP et al. · Journal of rehabilitation research and development, 2002

Abstract

Reconstructive microsurgery is performed to reattach, transfer, or transplant body tissues. Venous congestion is a complication that threatens the viability of the affected tissue and is often treated with medicinal leeches. Leech therapy has two phases: active bloodletting and passive bleeding from the leech wound after detachment, which can last for several hours. Unfortunately, the small blood volumes removed by medicinal leeches are generally ineffective in decongesting tissue. Our goal was to develop a device to augment blood removal during the passive-bleeding phase of leech therapy with the use of a porcine model of venous congestion. Results indicated that the use of the device resulted in significant increases in blood retrieval relative to reports of passive bleeding alone (141%, 156%, and 155% in 1, 2, and 3 hours, respectively). These results are an encouraging first step toward development of a mechanical device that completely replaces the use of medicinal leeches in modern medicine.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeEvaluation StudyJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.
Indexed MeSH termsAnimalsCombined Modality TherapyEquipment DesignLeechingPostoperative ComplicationsSuctionSurgical FlapsSwineVascular Diseases

Резюме

Porcine model device development showing 141-156% increased blood retrieval after leech detachment versus passive bleeding alone. Step toward mechanical alternative to medicinal leeches.

Почему это важно для гирудотерапии

This evaluation study tested a mechanical device designed to augment blood removal during the passive bleeding phase of leech therapy, using a porcine model of venous congestion. The device resulted in significant increases in blood retrieval compared to passive bleeding alone, presenting an alternative to medicinal leeches in managing tissue flap congestion. While this research is directly relevant to the ASH domain by addressing a known limitation of leech therapy—namely, the small volume of blood removed by leeches—the ultimate goal of the device is to completely replace the use of medicinal leeches in modern medicine. Additionally, the results are based solely on an animal model (swine) and lack human clinical validation.

Цитирование

Augmented blood removal after medicinal leech feeding in congested tissue flaps.

Connor NP et al. · Journal of rehabilitation research and development, 2002

Связанный клинический контекст

Узнайте, как это исследование связано с клинической практикой

Добавлено в библиотеку ASH: May 27, 2026 · Последнее обновление сайта: June 18, 2026

Этот сайт предоставляет образовательную информацию и не является медицинской консультацией, диагнозом или рекомендацией по лечению. Гирудотерапия сопряжена с клинически значимыми рисками и должна проводиться только квалифицированными клиницистами в рамках институционально утверждённых протоколов. Разрешение FDA 510(k) для медицинских пиявок ограничено определёнными показаниями; обсуждения исследовательского и нелицензионного применения отмечены соответствующим образом. Для индивидуальных медицинских рекомендаций обратитесь к квалифицированному медицинскому специалисту.