Sociedad Americana de Hirudoterapia

Leech bites: massive bleeding, coagulation profile disorders, and severe anemia

Case report published in American Journal of Emergency Medicine (2008)

Última actualización: June 18, 2026Revisado por: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Case reportSeguridad y control de infeccionesEnsayos clínicosKose A et al. · American Journal of Emergency Medicine, 2008

Abstract

Leeches have been in use for centuries, especially in plastic and reconstructive surgery wound and flap healing, in venous insufficiencies, and in the treatment of many disorders such as hemorrhoids and varicosity. With this study, we aimed to discuss coagulation disorder due to uncontrolled leech bites, consequent excessive skin hemorrhage, and anemia requiring blood transfusion. A 65-year-old male patient was referred to the emergency department because of excessive intractable bleeding that had occurred after leech bites. On physical examination, a total of 130 bites were detected on various regions of the body. In the laboratory findings of the patient, hemoglobin and hematocrit levels were extremely low, and prothrombin time, international normalized ratio, and partial thromboplastin time were markedly increased. The patient received a total of 8 units of fresh frozen plasma and 6 units of erythrocyte suspension. Bleeding stopped by decreasing after the transfusion of fresh frozen plasma. Although the complications due to leech injuries are rare, they may be an important cause of morbidity and mortality when an injury or prolonged bleeding in an internal region occurs. Prolonged skin hemorrhages rarely cause anemia, and deaths are caused by intractable hemorrhages. However, a coagulation disorder and consequent intractable hemorrhage have not been reported previously in the literature. In conclusion, it should be known that uncontrolled, blind, and excessive leech use causes severe hemorrhage and excessive blood loss, causing significant morbidity and mortality. Therefore, the awareness of either physicians or people using or recommending alternative medicine should be raised on this subject.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeCase ReportsJournal Article
Indexed MeSH termsAgedAnemiaAnimalsBites and StingsHemorrhageHumansLeechesMale

Resumen

65-year-old male with 130 leech bites developed coagulopathy with markedly elevated PT/INR/PTT, severe anemia, and required 8 units fresh frozen plasma and 6 units of erythrocyte suspension — illustrates morbidity of uncontrolled traditional leech application.

Por qué esto importa para la hirudoterapia

This case report describes a 65-year-old man with 130 leech bites who presented with excessive intractable bleeding, severe anemia (extremely low hemoglobin and hematocrit), and coagulation profile abnormalities (markedly increased prothrombin time, INR, and partial thromboplastin time), requiring 8 units of fresh frozen plasma and 6 units of erythrocyte suspension, with bleeding cessation following plasma transfusion. The authors state that coagulation disorder with consequent intractable hemorrhage from leech bites had not been previously reported in the literature. The report is directly relevant to ASH's domain as a serious safety concern, illustrating the potential morbidity of uncontrolled, excessive leech application. Caveat: This is a single case report involving an extreme number of bites (130) from uncontrolled alternative medicine use; the coagulation abnormalities may reflect pre-existing or leech-induced coagulopathy from massive anticoagulant exposure, and no systematic data on dose-response relationships or incidence are provided.

Citación

Leech bites: massive bleeding, coagulation profile disorders, and severe anemia.

Kose A et al. · American Journal of Emergency Medicine, 2008

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Añadido a la biblioteca ASH: May 27, 2026 · Última actualización del sitio: June 18, 2026

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