Ciprofloxacin-resistant Aeromonas hydrophila infection following leech therapy

Compromised flap perfusion can lead to the use of leech therapy to aid in flap salvage. Aeromonas hydrophila, a symbiont of the leech, is a well-known bacterial pathogen that has the potential to cause infection in patients receiving leech therapy. Ciprofloxacin is commonly regarded as the antibiotic of choice for prophylaxis against this pathogen. We present patient who underwent leech therapy during salvage attempts for a venous congested flap. A resultant infection developed despite being on appropriate antibiotics. Culture sensitivities indicated that A. hydrophila was resistant to ciprofloxacin.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Patient with venous-congested flap developed ciprofloxacin-resistant A. hydrophila infection despite appropriate prophylaxis. Review of literature on emerging resistance.

Explore cómo esta investigación se conecta con la práctica clínica

More peer-reviewed studies in Resistencia antimicrobiana.

• Novel Leech Antimicrobial Peptides — Hirunipins — Kumar et al. (2025)
• Leech therapy (Hirudo medicinalis) attenuates testicular damages induced by testicular ischemia/reperfusion in an animal model — Davoodi F et al. (2021)
• AIF-1 and RNASET2 Play Complementary Roles in the Innate Immune Response of Medicinal Leech — Baranzini N et al. (2019)
• Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens — Grafskaia E et al. (2019)
• Antimicrobial Role of RNASET2 Protein During Innate Immune Response in the Medicinal Leech — Baranzini N et al. (2020)
• Morganella Morganii Infection in Hirudo Medicinalis (Iran): A Case Report — Rahmati Holasoo H et al. (2022)
• Clinical efficacy of Jalaukawacharana (leech application) in Thrombosed piles — Bhagat P, Raut S, Lakhapati A (2012)
• Determination of disulfide linkages in antimicrobial peptides of the macin family by combination of top-down and bottom-up proteomics — Hung CW, Jung S, Grötzinger J, Gelhaus C, Leippe M, Tholey A (2014)
• Molecular characterization of two novel antibacterial peptides inducible upon bacterial challenge in an annelid, the leech Theromyzon tessulatum — Tasiemski A, Vandenbulcke F, Mitta G, Lemoine J, Lefebvre C, Sautière PE, Salzet M (2004)
• Macin family of antimicrobial proteins combines antimicrobial and nerve repair activities — Jung S, Sönnichsen FD, Hung CW et al. (2012)

Browse all ASH-analysed research →