Antithrombotic Strategies in Valvular and Structural Heart Disease Interventions: Current Status and Future Directions
Review published in Interventional cardiology clinics (2013)
Abstract
Antithrombotic prophylaxis is the cornerstone of adjunctive pharmacologic therapy in patients undergoing transcatheter intervention for valvular and structural heart disease. However, drugs and doses of antiplatelet and anticoagulant agents are mostly empiric for these indications and typically administered at the operator's discretion. This article describes the rationale for antithrombotic management of patients undergoing transcatheter aortic valve implantation, percutaneous mitral valve repair with the Mitraclip system, patent foramen ovale, and atrial septal defect closure, as well as common strategies for managing antiplatelet and anticoagulant therapy in patients with valvular and structural heart disease undergoing transcatheter procedures.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Resumen
Antithrombotic prophylaxis is the cornerstone of adjunctive pharmacologic therapy in patients undergoing transcatheter intervention for valvular and structural heart disease.
Por qué esto importa para la hirudoterapia
This review describes antithrombotic management strategies—including antiplatelet and anticoagulant therapy—for patients undergoing transcatheter procedures such as aortic valve implantation, Mitraclip, patent foramen ovale, and atrial septal defect closure. The authors note that drug choices and doses are largely empiric and operator-dependent. While anticoagulation is broadly relevant to the therapeutic context in which hirudin-derived drugs like bivalirudin are sometimes used, the abstract does not specifically mention hirudin, bivalirudin, leeches, or any leech-derived compounds. The relevance to ASH's domain of hirudotherapy and the leech secretome is minimal and entirely indirect.
Citación
Antithrombotic Strategies in Valvular and Structural Heart Disease Interventions: Current Status and Future Directions
Capodanno D et al. · Interventional cardiology clinics, 2013
Contexto clínico relacionado
Explore cómo esta investigación se conecta con la práctica clínica
Añadido a la biblioteca ASH: May 27, 2026 · Última actualización del sitio: June 18, 2026