Chinese herbal medicine for aspirin resistance: a systematic review of randomized controlled trials
Review published in Evidence-based complementary and alternative medicine : eCAM (2014)
Abstract
Aspirin resistance (AR) is a prevalent phenomenon and leads to significant clinical consequences, but the current evidence for effective interventional strategy is insufficient. The objective of this systematic review is thus to assess the efficacy and safety of Chinese herbal medicine (CHM) for AR. A systematical literature search was conducted in 6 databases until December 2012 to identify randomized controlled trials (RCTs) of CHM for AR. As a result, sixteen RCTs with a total of 1011 subjects were identified, suggesting that the interests of the medical profession and the public in the use of CHM for AR have grown considerably in the recent years. Tongxinluo capsule and Danshen-based prescriptions were the most frequently used herbal prescriptions, while danshen root, milkvetch root, Leech, and Rosewood were the most frequently used single herbs. Despite the apparent reported positive findings, it is premature to determine the efficacy and safety of CHM for the treatment of AR due to poor methodological quality and insufficient safety data. However, CHMs appeared to be well tolerated in all included studies. Thus, CHM as a promising candidate is worthy of improvement and development for further clinical AR trials. Large sample-size and well-designed rigorous RCTs are needed.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Резюме
Aspirin resistance (AR) is a prevalent phenomenon and leads to significant clinical consequences, but the current evidence for effective interventional strategy is insufficient.
Почему это важно для гирудотерапии
This systematic review of 16 RCTs (1,011 subjects) assessed Chinese herbal medicine for aspirin resistance, identifying leech as one of the four most frequently used single herbs alongside danshen root, milkvetch root, and rosewood, with Tongxinluo capsule and Danshen-based prescriptions being the most common formulations. For ASH's domain, this provides indirect evidence that leech-derived materials are incorporated into traditional Chinese medicine formulations used in the context of aspirin resistance. However, leech appears as one component within complex multi-herb preparations, so no conclusions about leech specifically can be drawn. The review found overall evidence premature due to poor methodological quality and insufficient safety data, and it does not involve live leech therapy or isolated leech compounds.
Цитирование
Chinese herbal medicine for aspirin resistance: a systematic review of randomized controlled trials
Liu AJ et al. · Evidence-based complementary and alternative medicine : eCAM, 2014
Связанный клинический контекст
Узнайте, как это исследование связано с клинической практикой
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