Antibiotic sensitivities of Aeromonas hydrophila cultured from medicinal leeches
Microbiology study published in Br J Plast Surg (1988)
Abstract
Increased use of medicinal leeches (Hirudo medicinalis) for the treatment of venous congestion in flaps and replanted parts has coincided with reports of soft tissue infections following leech application. We cultured the gullets of 20 medicinal leeches to re-examine the antibiotic sensitivities of Aeromonas hydrophila, the leech enteric organism associated with reported infections. These isolates reflected reported resistance to penicillin and first generation cephalosporins as well as sensitivity to gentamicin, tetracycline and chloramphenicol. Additionally, the cultures were sensitive to cefamandol, cefoxitin and two third generation cephalosporins (cefoperazone and cefotaxime). These findings suggest that cefamandol, cefoxitin and some third generation cephalosporins may have a role as perioperative antibiotics in replantation and flap surgery. These antibiotics might provide prophylaxis against Aeromonas hydrophila infection when leech use is required.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Резюме
Cultured 20 leech gullets confirmed Aeromonas hydrophila resistance to penicillin and first-generation cephalosporins, with sensitivity to gentamicin, tetracycline, chloramphenicol, cefamandol and cefoxitin.
Почему это важно для гирудотерапии
This study cultured the gullets of 20 medicinal leeches (Hirudo medicinalis) to re-examine antibiotic sensitivities of Aeromonas hydrophila, the enteric organism associated with soft tissue infections following leech application. Isolates showed resistance to penicillin and first-generation cephalosporins but sensitivity to gentamicin, tetracycline, chloramphenicol, cefamandol, cefoxitin, and third-generation cephalosporins (cefoperazone and cefotaxime). This is directly relevant to ASH's domain, providing evidence to guide perioperative antibiotic prophylaxis during leech therapy for flap and replantation surgery. The findings are limited to in vitro sensitivity data from 20 leech specimens, and the study does not provide clinical outcome data to confirm prophylactic efficacy of the identified antibiotics.
Цитирование
Antibiotic sensitivities of Aeromonas hydrophila cultured from medicinal leeches.
Hermansdorfer J et al. · British journal of plastic surgery, 1988
Связанный клинический контекст
Узнайте, как это исследование связано с клинической практикой
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