Successful local use of heparin calcium for congested fingertip replants
Observational published in Arch Plast Surg (2020)
Abstract
BACKGROUND: Conventional methods of external bleeding for congested fingertip replants exhibit notable problems, including uncontrollable bleeding and unpredictable survival of the replant. We have added a local injection of heparin calcium to the routine use of systemic heparinization for inducing external bleeding. We retrospectively examined patients who underwent external bleeding using our method. METHODS: Local subcutaneous injections of heparin calcium were made in 15 congested replants in addition to systemic heparinization. Each injection ranged from 500 to 5,000 U. The average duration of the injections was 4.1 days. Surgical outcomes were analyzed and compared with a control group of patients who underwent external bleeding without heparin calcium. RESULTS: The overall survival rate was 93.3%, which was higher than that of the control group (83.3%), but the difference was not statistically significant (P=0.569). The survival rate for subzones I and II by the Ishikawa subzone classification was 100%, whereas it was 87.5% in subzones III and IV. No statistically significant difference was observed. The rate of partial necrosis was 0% in subzones I and II, whereas it was significantly higher (66.7%) in subzones III and IV (P=0.015). The mean total blood loss via external bleeding was 588 g in 10 fingers. No patients required blood transfusion. CONCLUSIONS: Congestion of a replanted fingertip can be successfully managed without blood transfusion by our method. Although complete relief from congestion in replants in subzones I and II is achievable, there is a higher risk of partial necrosis in subzones III and IV.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Resumen
Series of 15 congested fingertip replants treated with local heparin calcium injection as a 'chemical leech' alternative; 93.3% survival rate with no blood transfusions required. Subzone IV cases had higher partial necrosis (66.7%).
Por qué esto importa para la hirudoterapia
Este estudio retrospectivo examinó inyecciones locales subcutáneas de heparina cálcica (500-5.000 U por inyección, media de 4,1 días) adicionadas a la heparinización sistémica para inducir sangrado externo en 15 reimplantes de punta de dedo congestionados. La tasa de supervivencia fue del 93,3 % (frente a 83,3 % en el control, NS), con una supervivencia del 100 % en las subzonas I-II de Ishikawa, pero una necrosis parcial significativamente mayor (66,7 %) en las subzonas III-IV; no se requirieron transfusiones. Para el ámbito de ASH, la relevancia es indirecta: el estudio aborda una alternativa a la terapia con sanguijuelas para el manejo de la congestión venosa en el reimplante digital, un escenario donde las sanguijuelas se utilizan frecuentemente. No involucra sanguijuelas. La nota debe indicar claramente que no se utilizaron sanguijuelas ni agentes derivados de sanguijuela, lo que hace que sea relevante solo como contexto comparativo para las estrategias de manejo de la congestión que pueden competir o complementar a la hirudoterapia.
Citación
Successful local use of heparin calcium for congested fingertip replants.
Kadota H et al. · Archives of plastic surgery, 2020
Contexto clínico relacionado
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Añadido a la biblioteca ASH: May 27, 2026 · Última actualización del sitio: 18 de junio de 2026