Outcomes of flap salvage with medicinal leech therapy
Retrospective study published in Microsurgery (2012)
Abstract
Medicinal leech therapy (MLT) to salvage venous congestion in native skin and local flaps is commonly practiced. However, the role of MLT in compromised regional and free flaps remains unclear. Leeches were used in 39 patients to treat venous congestion in native skin (n = 5), local flaps (n = 6), regional flaps (n = 14), and free flaps (n = 14). There were no total losses in patients with compromised native skin or local flaps. One patient who had received a radial forearm free flap expired before flap outcome could be assessed, and was excluded from analysis. Of the remaining 27 regional and free flaps, 33.3% were salvaged, 33.3% were partially salvaged, and 33.3% were lost. Means of 38.3 ± 34.0, 101.0 ± 11.2, and 157.9 ± 224.4 leeches and 1.7 ± 3.6, 3.2 ± 4.4, and 5.6 ± 5.2 units of blood were required for the salvaged, partially salvaged, and lost groups, respectively. Twenty-two patients required blood transfusion (57.9%). No patients developed wound infection with Aeromonas hydrophilia. Two patients developed donor site hematomas, and four patients developed recipient site hematomas. MLT is efficacious in congested native skin and local flaps. Some regional and free flaps can be totally or partially salvaged. However, the morbidity of MLT must be weighed against the risks of flap loss.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Resumen
39-patient series of leech therapy for venous congestion: 100% salvage in native skin and local flaps; 33.3% salvaged, 33.3% partially salvaged, 33.3% lost in regional/free flaps with 57.9% requiring transfusion.
Por qué esto importa para la hirudoterapia
Este estudio evaluó los desenlaces de la terapia con sanguijuelas medicinales (MLT) para la congestión venosa en 39 pacientes con piel nativa, colgajos locales, colgajos regionales y colgajos libres. Los hallazgos son directamente relevantes para la práctica de la hirudoterapia, al demostrar que la MLT no produjo pérdidas totales en los casos de piel nativa y colgajos locales, mientras que los 27 colgajos regionales y libres evaluables mostraron desenlaces distribuidos de forma equitativa (33,3 % salvados, 33,3 % parcialmente salvados, 33,3 % perdidos). El estudio reportó una morbilidad notable, con un 57,9 % de pacientes que requirieron transfusión sanguínea, aunque no se produjeron infecciones de herida por Aeromonas hydrophila. El resumen describe desenlaces comparativos entre tipos de colgajo, pero no indica la existencia de un grupo control sin sanguijuelas, por lo que la eficacia de la MLT en relación con intervenciones alternativas no puede evaluarse a partir de este resumen por sí solo.
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Añadido a la biblioteca ASH: May 27, 2026 · Última actualización del sitio: 18 de junio de 2026