Keratitis following leech therapy for periocular eczematous dermatitis: a case report
Case report published in BMC complementary medicine and therapies (2023)
Abstract
BACKGROUND: The medicinal leech therapy (MLT) is a kind of complementary treatment method used for various diseases. The leeches (Hirudo medicinalis) have been used for more than 2500 years by surgeons. The substances presenting in the saliva of leeches have anti-inflammatory, anticoagulant, platelet inhibitory, thrombin regulatory, analgesic, extracellular matrix degradative and antimicrobial effects. The method is cheap, easy to apply, effective and its mechanisms of action have been clarified for specific diseases. Infection particularly Aeromonas infection is the most common complication of MLT. CASE PRESENTATION: In this case report, a keratitis case developing after leech therapy applied for the periocular and facial eczematous dermatitis lesions will be presented. The patient referred to our hospital with decreased vision, ocular pain, stinging, redness and lacrimation complaints. A large corneal epithelial defect with irregular margins, dying by fluorescein, involving more than inferior half of cornea and conjunctival hyperemia were seen in the right eye. No agent was determined in microbiological investigation, as the patient had used topical moxifloxacin eye drop which was commenced in another clinic before applying to us. The patient was treated with fortified vancomycin and ceftazidime, before using besifloxacin with the diagnosis of bacterial keratitis. Three weeks later epithelial defect improved completely leaving an opacity and neovascularization. CONCLUSIONS: MLT should be performed by certified physicians with sterile medicinal leeches and precautious antibiotics should be used before MLT for prevention against potential infections.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Resumen
The medicinal leech therapy (MLT) is a kind of complementary treatment method used for various diseases. The leeches (Hirudo medicinalis) have been used for more than 2500 years by surgeons.
Por qué esto importa para la hirudoterapia
Este reporte de caso documenta a un paciente que desarrolló queratitis bacteriana tras terapia con sanguijuelas medicinales (MLT) aplicada para dermatitis eccematosa periocular y facial, que se presentó con disminución de la visión, dolor ocular y un extenso defecto epitelial corneal que afectaba más de la mitad inferior de la córnea. El reporte es directamente relevante para la seguridad de la hirudoterapia, ya que destaca una grave complicación ocular infecciosa consistente con la observación del resumen de que la infección—particularmente la infección por Aeromonas—es la complicación más frecuente de la MLT, y los autores recomiendan que el tratamiento sea realizado por médicos certificados utilizando sanguijuelas estériles con antibióticos profilácticos considerados previamente. Sin embargo, al tratarse de un único reporte de caso, no puede establecer incidencia, riesgo comparativo ni causalidad definitiva; además, no se aisló ningún agente microbiano, probablemente debido al uso previo de antibióticos tópicos, lo que limita la información microbiológica sobre el patógeno responsable.
Citación
Keratitis following leech therapy for periocular eczematous dermatitis: a case report.
Özkaya D · BMC complementary medicine and therapies, 2023
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Añadido a la biblioteca ASH: March 18, 2026 · Última actualización del sitio: June 18, 2026