Sociedad Americana de Hirudoterapia

Management of venous thrombosis in fibular free osseomusculocutaneous flaps used for mandibular reconstruction: clinical techniques and treatment considerations

Case report published in Head & face medicine (2010)

Última actualización: June 18, 2026Revisado por: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Case reportEnsayos clínicosDraenert FG et al. · Head & face medicine, 2010

Abstract

BACKGROUND: Mandibular reconstruction by means of fibula transplants is the standard therapy for severe bone loss after subtotal mandibulectomy. Venous failure still represents the most common complication in free flap surgery. We present the injection of heparine into the arterial pedicle as modification of the revising both anastomoses in these cases and illustrate the application with a clinical case example. METHODS: Methods consist of immediate revision surgery with clot removal, heparin perfusion by direct injection in the arterial vessel of the pedicle, subsequent high dose low-molecular weight heparin therapy, and leeches. After 6 hours postoperatively, images of early flap recovery show first sings of recovery by fading livid skin color. RESULTS: The application of this technique in a patient with venous thrombosis resulted in the complete recovery of the flap 60 hours postoperatively. Other cases achieved similar success without additional lysis Therapy or revision of the arterial anastomosis. CONCLUSION: Rescue of fibular flaps is possible even in patients with massive thrombosis if surgical revision is done quickly.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeCase ReportsJournal Article
Indexed MeSH termsAnticoagulantsBone TransplantationFibulaHeparinHumansMaleMandibleMiddle AgedOsteotomyPlastic Surgery ProceduresReoperationSurgical Flaps

Resumen

Mandibular reconstruction by means of fibula transplants is the standard therapy for severe bone loss after subtotal mandibulectomy.

Por qué esto importa para la hirudoterapia

This article describes a multimodal technique for managing venous thrombosis in fibular free flaps used for mandibular reconstruction, illustrated with a clinical case. The approach combined immediate surgical revision with clot removal, heparin perfusion via direct injection into the arterial pedicle, subsequent high-dose low-molecular-weight heparin therapy, and leeches. The abstract reports that the illustrated case achieved complete flap recovery within 60 hours, and notes that other cases achieved similar success without additional lysis therapy or arterial anastomosis revision. This article is directly relevant to hirudotherapy as it documents the inclusion of medicinal leeches within a combined protocol for venous congestion in surgical flaps. However, because multiple interventions were applied concurrently, the isolated contribution of leech therapy to outcomes cannot be determined from the abstract.

Citación

Management of venous thrombosis in fibular free osseomusculocutaneous flaps used for mandibular reconstruction: clinical techniques and treatment considerations

Draenert FG et al. · Head & face medicine, 2010

Contexto clínico relacionado

Añadido a la biblioteca ASH: May 27, 2026 · Última actualización del sitio: June 18, 2026

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