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RCTs
15Investigating the therapeutic potential of medical leech and leech saliva extract in flap survival: an in vivo study using rats
GRADE sehr niedrigÜnal K, Emre Erol M, Dayanır D, Deniz E, Ayhan H, Fındıkçıoğlu K (2025) · Journal of Complementary & Integrative Medicine
Efficiency of medical leech on experimentally induced incisional wound healing in rats
GRADE sehr niedrigBilden A, Kara O, Kahraman M, Caglayan N, Cicek M (2025) · Journal of Complementary & Integrative Medicine
Effects of hirudotherapy on liver functions, lipid profile, and insulin sensitivity in rats with metabolic syndrome
GRADE niedrigBilden A, Kocak S, Yildiz HT, Cakir F, Kahraman M, Cicek M (2026) · BMC Complementary Medicine and Therapies
Investigation of the therapeutic effects of medicinal leech treatment on lower extremity ischemia-reperfusion injury
GRADE niedrigUnal K, Samur B, Sharif A, Ibrahimkhanli L, Yumusak N (2026) · Journal of Complementary & Integrative Medicine
Evaluation of Methylene Blue as An Effective Antiseptic for Medicinal Leeches
GRADE sehr niedrigDoğan S, Farzali S, Karimova B, Sağlam N (2024) · Türkiye Parazitoloji Dergisi
Comparative genomics suggests extensive antithrombotic gene expansion in Haemadipsa yanyuanensis
GRADE sehr niedrigLin Y, Zhao F, Fan S, Yang D, Tong X, Tang L, Kong D, Lin G, Liu Z (2025) · BMC Genomics
Comparative Study of Hirustasin Superfamily Gene Expression in Two Medicinal Leeches, Hirudinaria manillensis and Whitmania pigra
GRADE sehr niedrigSun R, Ai R, Yin J, Cheng J, Huang Z, Tang L, Liu Z, Zeng Q, Zhao F, Lin G (2025) · Genes
Genetic Variation and Gene Expression of the Antimicrobial Peptide Macins in Asian Buffalo Leech (Hirudinaria manillensis)
GRADE sehr niedrigYu Y, Tang L, Xiao M, Yin J, Ye T, Sun R, Ai R, Zhao F, Huang Z, Lin G (2025) · Biology
Identification and Characterization of RK22, a Novel Antimicrobial Peptide from Hirudinaria manillensis against Methicillin Resistant Staphylococcus aureus
GRADE sehr niedrigLu X, Yang M, Zhou S, Yang S, Chen X, Khalid M, Wang K, Fang Y, Wang C, Lai R, Duan Z (2023) · International Journal of Molecular Sciences
Transcriptomic profiling and the first spatial expression analysis of candidate genes in the salivary gland of the East Asian medicinal leech, Hirudo nipponia
GRADE sehr niedrigKim JH, Lee CJ, Yu YS, Aryal YP, Kim S, Suh JY, Kim JY, Min SH, Cha IT, Lee HY, Shin SY, Cho SJ (2023) · Developmental and Comparative Immunology
Cloning, characterization, and heterologous expression of a candidate Hirudin gene from the salivary gland transcriptome of Hirudo nipponia
GRADE sehr niedrigShi P, Wei J, You H, Chen S, Tan F, Lu Z (2023) · Scientific Reports
Life without blood: Molecular and functional analysis of hirudins and hirudin-like factors of the Asian non-hematophagous leech Whitmania pigra
GRADE sehr niedrigMüller C, Wang Z, Hamann M, Sponholz D, Hildebrandt JP (2022) · Journal of Thrombosis and Haemostasis
Transcriptomic analysis of the salivary gland of medicinal leech Hirudo nipponia
GRADE sehr niedrigLu Z, Shi P, You H, Liu Y, Chen S (2018) · PLoS ONE
Hirudins and fenestrins of the African medicinal leech Asiaticobdella fenestrata
GRADE sehr niedrigSchulz L, Tolksdorf C, Rauch BH, Kvist S, Müller C (2025) · Parasitology Research
Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches
GRADE sehr niedrigBabenko VV, Podgorny OV, Manuvera VA, Kasianov AS, Manolov AI, Grafskaia EN, Shirokov DA, Kurdyumov AS, Vinogradov DV, Nikitina AS, Kovalchuk SI, Anikanov NA, Butenko IO, Pobeguts OV, Matyushkina DS, Rakitina DV, Kostryukova ES, Zgoda VG, Baskova IP, Trukhan VM, Gelfand MS, Govorun VM, Schiöth HB, Lazarev VN (2020) · BMC Genomics