Complete penile amputation during ritual neonatal circumcision and successful replantation using postoperative leech therapy
Banihani OI, Fox JA, Gander BH, Grunwaldt LJ, Cannon GM (2014) · Urology · n=1
Детали доказательств RCTСсылка на исследование
GRADE Очень низкаяНедостаточно доказательствСостояние: Microsurgical Replantation (Digit / Ear / Scalp) →
Характеристика исследования
- Дизайн
- single-patient case report (7-day-old neonate, Children's Hospital of Pittsburgh of UPMC)
- Размер выборки (n)
- 1
- Вмешательство
- Microvascular replantation of completely amputated penis at penopubic junction (Mogen clamp injury during circumcision) with postoperative leech therapy
- Компаратор
- No control - single case report
- Первичная конечная точка
- Penile salvage and functional restoration
- Основной результат
- First reported neonatal penile amputation replantation with postoperative leech therapy; successful tissue survival with leech-mediated venous decongestion
- Длительность наблюдения
- Postoperative hospitalization with subsequent outpatient follow-up
- PMID
- 24928459
Ключевые выводы
- First reported neonatal penile leech therapy for replantation
- Mogen clamp circumcision complication context
- Successful tissue survival with leech-mediated venous decongestion
- Penopubic junction amputation level
- Documents US K040187 application in 7-day-old patient
Ограничения
- Single case - no generalizable conclusions
- Limited long-term follow-up reporting
- Functional outcomes uncertain at age 7 days
- Cannot quantify leech vs surgical contribution
- Extreme age limits protocol transfer
Клиническое значение
Banihani 2014 documents the youngest reported leech therapy patient in penile replantation literature. For US clinicians under K040187, the case demonstrates feasibility of the device indication in neonates but raises proportional dose/duration questions. The Mogen clamp circumcision complication context highlights leech therapy's role in iatrogenic injury salvage.
Связанные исследования
Successful Microsurgical Replantation of Amputated Penis: A Case Report and Review of Literature
Akhoondinasab MR, Farahmand HR, Zahedi A, Saraee A (2023)
Leeches and Caudal Analgesia After Replantation for Glans Amputation During Neonatal Circumcision
Mousa A, Keefe DT, Wong K, Davidge K, Lorenzo AJ, Dos Santos J (2022)
Penile Replantation: A Review of Microsurgical Techniques, Patient Outcomes, and Solutions to Complex Reconstructive Challenges
Arbel EJ, Reese AD, Richards R, Singh S, O'Shea AW, Hennig F, Abramowitz D (2024)
Medicinal Leech Therapy in Urology: A PRISMA-Compliant Systematic Review
Battin AO, Hobeika N, Zdilla MJ (2023)