Non-Occlusive Mesenteric Ischemia Due to Hirudotherapy: A Case Report
Akalın Ç, Ekmen N (2020) · Cureus · n=1
Характеристика исследования
- Дизайн
- single-patient case report (57-year-old male, Ordu University Training and Research Hospital, Turkey)
- Размер выборки (n)
- 1
- Вмешательство
- Hirudotherapy applied to diabetic foot wounds with subsequent prolonged uncontrollable bleeding and non-occlusive mesenteric ischemia
- Компаратор
- Conventional diabetic foot wound care
- Первичная конечная точка
- Identification of severe hirudotherapy adverse event - non-occlusive mesenteric ischemia
- Основной результат
- Excessive bleeding from leech bites caused hypovolemia and non-occlusive mesenteric ischemia; CT showed hepatic portal venous gas and pneumatosis intestinalis; laparotomy revealed necrosis of terminal ileum and entire colon; necrotic segments resected with end-ileostomy; patient discharged day 17
- Длительность наблюдения
- 17 days hospitalization with surgical resection
- PMID
- 32874797
Ключевые выводы
- Non-occlusive mesenteric ischemia from hirudotherapy bleeding
- Hypovolemia-driven splanchnic hypoperfusion
- Necrosis of terminal ileum and entire colon required resection
- End-ileostomy permanent at discharge
- Critical safety signal for unsupervised hirudotherapy
Ограничения
- Single case - cannot quantify incidence
- Diabetic foot wound treatment context may amplify risk
- Unable to establish causal link with full certainty
- Cannot recommend protocol changes from single case
- Patient demographics specific to Turkish clinical context
Клиническое значение
Akalın 2020 documents a catastrophic outcome (ischemic bowel necrosis requiring colectomy) from prolonged bleeding after off-label hirudotherapy for diabetic foot wounds. For US clinicians under K040187, this case reinforces the device's restricted indication (postoperative venous congestion in supervised settings) and the dangers of unsupervised use. Critical patient safety education content.
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Leech Me Alone! Atraumatic Hemarthrosis after Hirudotherapy
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Leech-bite induced anaphylaxis with or without Hymenoptera venom sensitization
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Time to Reconsidering the Potential Role of Leech Salivary Proteins in Medicine: Type-II Kounis Syndrome Triggered by Leech Bite
Tas S, Yildiz BS, Ersin A, Tas U (2025)
Unusual, Uncommon, Intriguing, and Significant Causes of Kounis Syndrome: Important Medications and Chemicals Used to Treat Kounis Syndrome and Myocardial Infarction Can Cause Kounis Syndrome
Kounis NG, de Gregorio C, Hung MY, Giamouzis G, Michalaki MA, Özkan U, Ceasovschih A, Mplani V, Dousdampanis P, Kouni SN, Stefanidis A, Nastouli KM, Bozika M, Patsouras N, Koniari I (2025)