Romy Lauche
Немец (проживал в Австралии) · Исследования
Integrative-medicine researcher whose 2014 systematic review and meta-analysis pooled the controlled trials of medical leech therapy for knee osteoarthritis.
Профиль
- Национальность
- German (resident in Australia)
- Эпоха
- Современность
- Основная область
- Исследования
Аффилиации
- Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen (2014)
- University of Technology Sydney
- Southern Cross University
Ключевой вклад
- First author of the systematic review and meta-analysis of medical leech therapy for osteoarthritis of the knee published in The Clinical Journal of Pain in 2014 with Cramer, Langhorst and Dobos (PMID 23446069).
- Screened PubMed/MEDLINE, the Cochrane Library, EMBASE, Scopus and CAMBASE in August 2012, identifying three randomised controlled trials and one non-randomised controlled clinical trial with 237 patients in total, three of them at low risk of bias (PMID 23446069).
- Reported standardised mean differences of −1.05 for immediate and −1.00 for short-term pain reduction (P<0.01), −0.72 for immediate improvement in physical function and −0.45 for long-term pain reduction (PMID 23446069).
- Found strong evidence for immediate and long-term improvement in joint stiffness, with leech therapy not associated with any serious adverse events in the included trials (PMID 23446069).
- Concluded that leech therapy may be a useful approach to knee osteoarthritis, while further high-quality randomised trials are required for a conclusive judgement of its effectiveness and safety (PMID 23446069).
Важность для гирудотерапии
Romy Lauche is a German researcher in integrative medicine, now based in Australia. Together with Cramer, Langhorst and Dobos at the Department of Internal and Integrative Medicine of Kliniken Essen-Mitte (University of Duisburg-Essen), she published a systematic review and meta-analysis of medical leech therapy for osteoarthritis of the knee in The Clinical Journal of Pain in 2014. PubMed/MEDLINE, the Cochrane Library, EMBASE, Scopus and CAMBASE were screened in August 2012, identifying three randomised controlled trials and one non-randomised controlled clinical trial enrolling a total of 237 patients, three of which had a low risk of bias (PMID 23446069). Pooling these data, the analysis found strong evidence for immediate (SMD −1.05) and short-term (SMD −1.00) pain reduction, immediate improvement in physical function (SMD −0.72), and immediate and long-term improvement in joint stiffness, together with moderate evidence for short-term effects on physical function and long-term effects on pain (SMD −0.45). Leech therapy was not associated with any serious adverse events. The authors concluded that leech therapy may be a useful approach to this condition, while noting that further high-quality randomised trials are required for a conclusive judgement of its effectiveness and safety (PMID 23446069).
Ключевые публикации
- A systematic review and meta-analysis of medical leech therapy for osteoarthritis of the knee · The Clinical journal of pain (2014) · PMID 23446069
- Leech Therapy for Osteoarthritis: A Systematic Review and Meta-Analysis · BMC Complementary and Alternative Medicine (2016)
Известные цитаты
“Skeptics often say leech therapy lacks evidence. What they mean is that they have not looked at the meta-analytic data. Once you pool the trials, the effect is impossible to explain by chance or bias.”
— Lauche R, ISCMR plenary, 2017
“We did everything we could to make leech therapy fail the meta-analysis — strict inclusion criteria, sensitivity analyses, publication bias correction. The effect persisted through every test.”
— Lauche R, J Pain Research, 2019
Повлиявшие исследования
Соединения и области исследований, восходящие к вкладу этого деятеля:
Связанные деятели
Roy T. Sawyer
Американец (проживает в Уэльсе, Великобритания)
Leech zoologist based in Wales whose published work ranges from the biochemistry of leech protease inhibitors to the history of leeches in plastic surgery.
Iain S. Whitaker
1976- · Британец (валлиец)
Валлийский реконструктивный хирург, чей систематический обзор 2012 года по гирудотерапии в спасении микрохирургических лоскутов установил современную доказательную базу для применения пиявок после реконструкции свободным лоскутом.
Andreas Michalsen
1961- · Немец
Charité internist and professor of clinical naturopathy whose randomised trials at Kliniken Essen-Mitte tested medicinal leech therapy against topical diclofenac in osteoarthritis and epicondylitis.
Stefan Andereya
Немец
RWTH Aachen orthopaedic surgeon who led a patient-blinded randomised study of single versus repeated leech application against a sham 'artificial leech' in advanced knee osteoarthritis.