Ronald A. Sherman
Estadounidense · Investigación
American physician-researcher whose reviews documented the modern revival of maggot debridement therapy and its mechanisms, and who co-edited work on biotherapy that includes hirudotherapy.
Perfil
- Nacionalidad
- American
- Época
- Contemporánea
- Campo principal
- Investigación
Afiliaciones institucionales
- BioTherapeutics, Education and Research (BTER) Foundation, Irvine, California (PubMed affiliations 2009, 2014)
Contribuciones clave
- Sole author of the 2009 review in the Journal of Diabetes Science and Technology describing the renaissance of maggot therapy eighty years after William Baer's work, attributing it to reliable access to a perishable medical device, simplified application, low-cost production and modern dressings that minimise the risk of escaping maggots (PMID 20144365).
- Reported that dozens of laboratories worldwide, served by overnight couriers, had made medicinal maggots readily available, and that studies show fears of patient non-acceptance to be unfounded (PMID 20144365).
- Sole author of the 2014 review in Evidence-Based Complementary and Alternative Medicine examining the three mechanisms attributed to medicinal maggots — debridement, disinfection and hastened wound healing — on the basis of controlled clinical studies and laboratory investigations (PMID 24744812).
- Concluded that clinical and laboratory data strongly support effective and efficient debridement, while clinical evidence for hastened wound healing remains meagre, and proposed using medicinal maggots as a 'maintenance debridement' modality beyond the point of gross debridement (PMID 24744812).
Importancia para la hirudoterapia
Ronald A. Sherman is an American researcher affiliated with the BioTherapeutics, Education and Research (BTER) Foundation in Irvine, California (PubMed affiliations 2009 and 2014), whose reviews trace the modern revival of maggot therapy. Writing in the Journal of Diabetes Science and Technology in 2009, he placed the field eighty years after William Baer presented his work treating bone and soft-tissue infections with live maggots, and attributed the treatment's renaissance to technological advances: reliable access to a perishable medical device, simplified application, low-cost production and modern dressings that minimise the risk of escaping maggots. He noted that dozens of laboratories worldwide, supported by overnight courier services, had made medicinal maggots readily available, and that studies show fears of patient non-acceptance to be unfounded (PMID 20144365). In a 2014 review in Evidence-Based Complementary and Alternative Medicine he examined the three mechanisms attributed to medicinal maggots — debridement, disinfection and hastened wound healing — drawing on controlled clinical studies and laboratory investigations of maggot–host interactions at the cellular and molecular level. He concluded that clinical and laboratory data strongly support effective and efficient debridement, whereas clinical evidence for hastened healing remains meagre, with laboratory studies and small replicated clinical studies suggesting that maggots promote tissue growth during and shortly after their presence on the wound, and he proposed employing maggots as a 'maintenance debridement' modality beyond the point of gross debridement (PMID 24744812). His relevance to hirudotherapy lies in the biotherapy field he helped organise; ASH's statements about his editorial and society roles remain subject to ongoing source verification.
Publicaciones clave
- Maggot therapy takes us back to the future of wound care: new and improved maggot therapy for the 21st century · Journal of Diabetes Science and Technology (2009) · PMID 20144365
- Mechanisms of maggot-induced wound healing: what do we know, and where do we go from here? · Evidence-Based Complementary and Alternative Medicine (2014) · PMID 24744812
- Maggot debridement therapy: a comprehensive review · Wound Repair and Regeneration (2007)
Investigación influenciada
Compuestos y áreas de investigación que se remontan a las contribuciones de esta figura:
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