Intelligente Bibliothek
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RCTs
52Leech therapy for symptomatic treatment of knee osteoarthritis: results and implications of a pilot study
GRADE niedrigAndereya S, Stanzel S, Maus U, Mueller-Rath R, Mumme T, Miltner O (2006) · Alternative Therapies in Health and Medicine
Effectiveness of leech therapy in osteoarthritis of the thumb carpometacarpal joint: a randomized controlled trial
GRADE niedrigMichalsen A, Lüdtke R, Cesur Ö, Afra D, Musial F, Baecker M, Dobos GJ (2008) · Pain
Leech therapy versus topical diclofenac for thumb carpometacarpal osteoarthritis: a randomized pilot study
GRADE niedrigAndereya S, Stanzel S, Maus U, Mueller-Rath R (2008) · Zeitschrift für Orthopädie und Unfallchirurgie
Leech therapy for chronic non-specific low back pain: a randomized controlled trial
GRADE niedrigHohmann CD, Stange R, Steckhan N, Robens S, Ostermann T, Paetow A, Michalsen A (2018) · Deutsches Ärzteblatt International
Leech therapy versus compression stockings for symptomatic varicose veins: open-label randomized controlled trial
GRADE niedrigKalender ME, Comez G, Sevinc A, Dirier A, Camci C (2014) · Phlebology
Medicinal leech therapy on head and neck patients: a review and case series of finger and digit replantation salvage
GRADE niedrigElyassi AR, Terres J, Rowshan HH (2014) · Journal of Oral and Maxillofacial Surgery
Effects of leech therapy on knee osteoarthritis: a randomized clinical trial in an Iranian population
GRADE niedrigKhoshnevisan A, Sahebkar A, Mohammadpour AH, Mosaffa-Jahromi M (2022) · Journal of Traditional and Complementary Medicine
Leech therapy in chronic shoulder pain: a randomized pilot study
GRADE niedrigMüller IM, Stange R, Heider U, Uehleke B, Cesur Ö, Michalsen A (2010) · Forschende Komplementärmedizin
Leech therapy for postherpetic neuralgia: a single-blind pilot trial
GRADE niedrigMueller IM, Stange R, Michalsen A (2012) · Schmerz (Berlin, Germany)
Leech therapy in chronic myofascial temporomandibular disorder: a randomized pilot trial
GRADE niedrigCesur Ö, Stange R, Michalsen A, Lüdtke R (2019) · Journal of Oral Rehabilitation
Leech therapy for postoperative pain and swelling after knee arthroscopy: a randomized controlled trial
GRADE niedrigBishaw AM, El-Sayed M, Hassan H, Ibrahim M (2020) · Egyptian Rheumatology and Rehabilitation
Effectiveness of leech therapy in chronic lateral epicondylitis: a randomized controlled trial
GRADE niedrigBäcker M, Lüdtke R, Afra D, Cesur Ö, Langhorst J, Fink M, Bachmann J, Dobos GJ, Michalsen A (2011) · The Clinical Journal of Pain
Randomised controlled trial with medical leeches for osteoarthritis of the knee
GRADE niedrigStange R, Moser C, Hopfenmueller W, Mansmann U, Buehring M, Uehleke B (2012) · Complementary Therapies in Medicine
Medicinal leeches and the microsurgeon: a four-year study, clinical series and risk benefit review
GRADE niedrigWhitaker IS, Josty IC, Hawkins S, Azzopardi E, Naderi N, Graf J, Damaris L, Lineaweaver WC, Kon M (2011) · Microsurgery
Efficacy and safety of topical hirudin (Hirudex): a double-blind, placebo-controlled study
GRADE niedrigStamenova PK, Marchetti T, Simeonov I (2001) · European Review for Medical and Pharmacological Sciences
Comparisons of medicinal leech therapy with venous catheterization in the treatment of venous congestion of the sural flap
GRADE niedrigMozafari N, Ghazisaidi MR, Hosseini SN, Abdolzadeh M (2010) · Microsurgery
Chemical and mechanical alternatives to leech therapy: a systematic review and critical appraisal
GRADE niedrigAzzopardi EA, Whitaker IS, Rozen WM, Naderi N, Kon M (2011) · Journal of Reconstructive Microsurgery
Conservative treatment of thumb base osteoarthritis: a systematic review
GRADE niedrigSpaans AJ, van Minnen LP, Kon M, Schuurman AH, Schreuders AR, Vermeulen GM (2015) · The Journal of Hand Surgery
Prophylactic versus reactive leech therapy for venous congestion after fingertip replantation: A retrospective comparative study and literature review
GRADE niedrigKameda Y, Motomiya M, Watanabe N, Ota M, Iwasaki N (2025) · JPRAS Open
Standardized protocol for artery-only fingertip replantation
GRADE niedrigBuntic RF, Brooks D (2010) · The Journal of Hand Surgery
Determining the appropriate number and duration of leech therapy in congested tissues using tissue spectrophotometry and laser Doppler flowmetry
GRADE niedrigRothenberger J, Petersen W, Schaller HE, Held M (2016) · Wound Repair and Regeneration
Comparison of the effectiveness of medicinal leech and TENS therapy in the treatment of primary osteoarthritis of the knee: a randomized controlled trial
GRADE niedrigIsik M, Ugur M, Yakisan RS, Sari T, Yilmaz N (2017) · Zeitschrift für Rheumatologie
Efficacy and Safety of Hirudotherapy for Improving Sperm Quality Parameters in Male Infertility: A Randomized Controlled Trial
GRADE niedrigAbtahi-Forooshani MS, Roozbehani S, Fatemi M, Noori A (2026) · Health Science Reports
Antimicrobial prophylaxis during Hirudo medicinalis therapy: a multicenter study
GRADE niedrigKruer RM, Barton CA, Roberti G, Gilbert B, McMillian WD (2014) · Journal of Reconstructive Microsurgery
Management of complications and compromised free flaps following major head and neck surgery
GRADE niedrigKucur C, Durmus K, Uysal IO, Old M, Agrawal A, Arshad H, Teknos TN, Ozer E (2015) · European Archives of Oto-Rhino-Laryngology
Current concepts in salvage procedures for failing microvascular flaps: is there a superior technique? Insights from a systematic review of the literature
GRADE niedrigTroeltzsch M, Troeltzsch M, Probst FA, Ristow O, Ehrenfeld M, Otto S (2016) · International Journal of Oral and Maxillofacial Surgery
The Use of Medicinal Leeches for the Treatment of Venous Congestion in Replanted or Revascularized Digits
GRADE niedrigArami A, Gurevitz S, Palti R, Menachem S, Berelowitz M, Yaffe B (2018) · Journal of Hand Surgery (American Volume)
The efficacy of arterial only microsurgical nasal replantation: a systematic review
GRADE niedrigSecanho MS, Rajaram R, de Menezes Neto BF, Cavale N, Ng SK, Neto AAP (2024) · ANZ Journal of Surgery
Microbiota Dynamics: A Key Factor in Hirudotherapy-Related Infections?
GRADE niedrigKarasartova D, Arslan-Akveran G, Sensoz S, Mumcuoglu KY, Taylan-Ozkan A (2025) · Microorganisms
Effects of hirudotherapy on liver functions, lipid profile, and insulin sensitivity in rats with metabolic syndrome
GRADE niedrigBilden A, Kocak S, Yildiz HT, Cakir F, Kahraman M, Cicek M (2026) · BMC Complementary Medicine and Therapies
Investigation of the therapeutic effects of medicinal leech treatment on lower extremity ischemia-reperfusion injury
GRADE niedrigUnal K, Samur B, Sharif A, Ibrahimkhanli L, Yumusak N (2026) · Journal of Complementary & Integrative Medicine
Leeches and hand surgery: history, physiology, and a scoping review
GRADE niedrigChabridon AI, Coquerel-Beghin D, Leger M, Baamir A, Bazeli A, Auquit-Auckbur I (2026) · Hand Surgery and Rehabilitation
Analysis of antibiotic resistant infections associated with hirudotherapy
GRADE niedrigBrauer PR, Saadah M, Fritz MA, Wu SS, Lamarre ED (2024) · American Journal of Otolaryngology
Applications of leech therapy in medicine: a systematic review
GRADE niedrigHosseini M, Jadidi A, Derakhshan Barjoei MM, Salehi M (2024) · Frontiers in Medicine
The Use of Medicinal Leeching in Breast Surgery: A Systematic Review
GRADE niedrigRajaram R, Cevik J, Bhindi N, Seth I, Rozen WM (2024) · Journal of Clinical Medicine
A Systematic Review of Complementary and Alternative Veterinary Medicine: Miscellaneous Therapies
GRADE niedrigBergh A, Lund I, Boström A, Hyytiäinen H, Asplund K (2021) · Animals
Impact of Bivalirudin on Ischemia/Reperfusion Injury in Patients with Reperfused STEMI Assessed by Cardiac Magnetic Resonance
GRADE niedrigZhang Y, Zou Z, Xu B, Chen B, Ge H, Ding S, Pu J (2024) · Pharmaceuticals
Safety of Bivalirudin Combined with Ticagrelor in the Emergency PCI in Patients with Acute ST-Segment Elevation Myocardial Infarction
GRADE niedrigWang ZD, Chen YX, Liu M, Li P, Liang XW, Zhu XZ, Xie WC, Liao W (2022) · Clinical and Applied Thrombosis/Hemostasis
Effect of Perioperative Antithrombotics on Head and Neck Microvascular Free Flap Survival After Anastomotic Revision
GRADE niedrigBishop JL, Vasudev M, Garcia N, Heslop G, Pham TT, Hicks MD, Chowdhury F, Grayson JW, Goddard JA, Tjoa T, Haidar Y, Thomas CM (2023) · Otolaryngology — Head and Neck Surgery (American Academy of Otolaryngology)
Prospective Randomized Pilot Study Comparing Bivalirudin Versus Heparin in Neonatal and Pediatric Extracorporeal Membrane Oxygenation
GRADE niedrigMcMichael A, Weller J, Li X, Hatton L, Zia A, Raman L (2024) · Pediatric Critical Care Medicine
Efficacy of Bivalirudin for Therapeutic Anticoagulation in COVID-19 Patients Requiring ECMO Support
GRADE niedrigTrigonis R, Smith N, Porter S, Anderson E, Jennings M, Kapoor R, Hage C, Moiz S, Garcia J, Rahman O (2021) · Journal of Cardiothoracic and Vascular Anesthesia
Bivalirudin versus heparin anticoagulation in patients receiving extracorporeal membrane oxygenation
GRADE niedrigHuang D, Guan Q, Qin J, Shan R, Wu J, Zhang C (2022) · Perfusion
Heparin-based versus bivalirudin-based anticoagulation in pediatric extracorporeal membrane oxygenation: A systematic review
GRADE niedrigValdes CA, Sharaf OM, Bleiweis MS, Jacobs JP, Mumtaz M, Sharaf RM, Jeng EI, Peek GJ (2023) · Frontiers in Medicine
Comparison of Bivalirudin Versus Heparin for Anticoagulation During Extracorporeal Membrane Oxygenation
GRADE niedrigHasegawa D, Sato R, Prasitlumkum N, Nishida K, Keaton B, Acquah SO, Im Lee Y (2022) · ASAIO Journal
Heparin Versus Bivalirudin for Anticoagulation in Adult Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-Analysis
GRADE niedrigWieruszewski PM, Macielak SA, Nei SD, Moman RN, Seelhammer TG, Nabzdyk CGS, Gerberi DJ, Mara KC, Hooten WM, Wittwer ED (2022) · ASAIO Journal
Bivalirudin or heparin for systemic anticoagulation during pediatric extracorporeal membrane oxygenation: Multicenter retrospective study
GRADE niedrigHamzah M, Seelhammer TG, Beshish AG, Byrnes J, Yabrodi M, Szadkowski A, Lutfi R, Andrijasevic N, Hock K, Worley S, Macrae DJ (2023) · Thrombosis Research
Is bivalirudin an alternative anticoagulant for extracorporeal membrane oxygenation (ECMO) patients? A systematic review and meta-analysis
GRADE niedrigLi DH, Sun MW, Zhang JC, Zhang C, Deng L, Jiang H (2021) · Thrombosis Research
Bivalirudin Monitoring in Pediatric Ventricular Assist Device and Extracorporeal Membrane Oxygenation: Analysis of Single-Center Retrospective Cohort Data 2018-2022
GRADE niedrigEngel ER, Perry T, Block M, Palumbo JS, Lorts A, Luchtman-Jones L (2024) · Pediatric Critical Care Medicine
Improved outcomes with pulsatile paracorporeal ventricular assist device support in children: A single-center experience
GRADE niedrigIaprintsev V, Fricke TA, Buratto E, Zubritskiy A, Perrier S, Eastaugh L, Barnes C, Sheridan B, Naimo PS, Brizard CP, Mathew J, Konstantinov IE (2025) · JTCVS Open
Burden of illness of non-hematopoietic stem cell transplant-related hepatic sinusoidal obstruction syndrome: A systematic review
GRADE niedrigFan L, Stewart F, Ruiz K, Devani D, Fusco N, Gill M, Amber V, Su W, Gangi A, Hanvesakul R (2024) · Heliyon
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