Flap infection associated with medicinal leeches in reconstructive surgery: two new drug-resistant organisms
Bibbo C, Fritsche T, Stemper M, Hall M (2013) · Journal of Reconstructive Microsurgery · n=2
Характеристика исследования
- Дизайн
- two-case report with management protocol review (Marshfield Clinic, Wisconsin)
- Размер выборки (n)
- 2
- Вмешательство
- Standard leech therapy in reconstructive surgery patients with subsequent identification of two new multidrug-resistant organisms causing flap infection
- Компаратор
- Standard Aeromonas hydrophila-targeted prophylactic regimens (proven inadequate for these strains)
- Первичная конечная точка
- Identification of novel resistant organisms and clinical management protocol
- Основной результат
- Two new multidrug-resistant organisms identified from medicinal leech therapy resulting in flap infection; suspected leech-borne infection evaluation and management protocol presented
- Длительность наблюдения
- Postoperative infection course
- PMID
- 23599212
Ключевые выводы
- Two new multidrug-resistant organisms identified
- Beyond traditional Aeromonas hydrophila coverage
- Comorbidities: arthropathy, obesity (morbid)
- Management protocol for suspected leech-borne resistant infections
- Supports antibiogram-guided empiric therapy
Ограничения
- Only 2 cases - cannot characterize population resistance
- Single institution experience
- Specific organisms not detailed in abstract
- Underlying comorbidities may select for resistant flora
- Cannot recommend universal protocol changes
Клиническое значение
Bibbo 2013 documents two novel multidrug-resistant organisms from medicinal leech therapy and provides clinical management protocol. For US clinicians under K040187, the case report highlights the need for individualized microbiologic evaluation in suspected leech-borne infections, particularly in patients with significant comorbidities (obesity, joint disease).
Связанные исследования
Infections Associated with Treatment with Hirudo medicinalis - Report of Two Cases and Review of the Literature
Reese K, Gümbel D, Seifert J, Daeschlein G, Napp M, Ekkernkamp A (2015)
The role of leech water sampling in choice of prophylactic antibiotics in medical leech therapy
Wilmer A, Slater K, Yip J, Carr N, Grant J (2013)
Low-Level Antimicrobials in the Medicinal Leech Select for Resistant Pathogens That Spread to Patients
Beka L, Fullmer MS, Colston SM, Nelson MC, Talagrand-Reboul E, Walker P, Ford B, Whitaker IS, Lamy B, Gogarten JP, Graf J (2018)
Infection following Leech Therapy for the Treatment of Nipple-Areola Complex Congestion after Breast Reduction: A Case Report
Torresetti M, Peltristo B, Taddei FMJ, Di Benedetto G (2024)