Leech Ecotin-like Factor
Trypsin and Factor Xa inhibitor with broad-spectrum serine protease activity.
Доклинические / механистические данныеLast updated: 2026-05-26 · Reviewed by ASH Editorial Board
Mechanistic Evidence Box
Preclinical / mechanistic- Page type
- Compound profile
- Evidence type
- Trypsin and Factor Xa inhibitor with broad-spectrum serine protease activity.
- Evidence level
- In vitro
- Drug vs leech
- Purified natural compound
- Safety domains
- Bleeding
Clinical translation limit
This factor's in vitro inhibition of trypsin and Factor Xa does not establish clinical efficacy. No FDA-approved derivative exists. Mechanism is preclinical/biochemical only.
Molecular Profile
- Category
- Proteinase Inhibitor
- Evidence tier
- Preclinical
- Molecular weight
- 16,000 Da
- Source species
- Hirudo medicinalis
Biological Targets
- → trypsin family serine proteases
- → Factor Xa
External Resources
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