Chinese herbal medicine for aspirin resistance: a systematic review of randomized controlled trials
Review published in Evidence-based complementary and alternative medicine : eCAM (2014)
Abstract
Aspirin resistance (AR) is a prevalent phenomenon and leads to significant clinical consequences, but the current evidence for effective interventional strategy is insufficient. The objective of this systematic review is thus to assess the efficacy and safety of Chinese herbal medicine (CHM) for AR. A systematical literature search was conducted in 6 databases until December 2012 to identify randomized controlled trials (RCTs) of CHM for AR. As a result, sixteen RCTs with a total of 1011 subjects were identified, suggesting that the interests of the medical profession and the public in the use of CHM for AR have grown considerably in the recent years. Tongxinluo capsule and Danshen-based prescriptions were the most frequently used herbal prescriptions, while danshen root, milkvetch root, Leech, and Rosewood were the most frequently used single herbs. Despite the apparent reported positive findings, it is premature to determine the efficacy and safety of CHM for the treatment of AR due to poor methodological quality and insufficient safety data. However, CHMs appeared to be well tolerated in all included studies. Thus, CHM as a promising candidate is worthy of improvement and development for further clinical AR trials. Large sample-size and well-designed rigorous RCTs are needed.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Resumen
Aspirin resistance (AR) is a prevalent phenomenon and leads to significant clinical consequences, but the current evidence for effective interventional strategy is insufficient.
Por qué esto importa para la hirudoterapia
Esta revisión sistemática de 16 ECA (1.011 sujetos) evaluó la medicina herbal china para la resistencia a la aspirina, identificando a la sanguijuela como una de las cuatro hierbas únicas más frecuentemente utilizadas junto con la raíz de danshen, la raíz de astrágalo y el palo de rosa, siendo el cápsula Tongxinluo y las preparaciones a base de Danshen las formulaciones más comunes. Para el ámbito de la ASH, esto proporciona evidencia indirecta de que los materiales derivados de sanguijuela se incorporan a formulaciones de la medicina tradicional china utilizadas en el contexto de la resistencia a la aspirina. Sin embargo, la sanguijuela aparece como un componente dentro de preparaciones complejas multi-herbales, por lo que no se pueden extraer conclusiones sobre la sanguijuela en concreto. La revisión concluyó que la evidencia global es prematura debido a la baja calidad metodológica y a datos insuficientes de seguridad, y no involucra hirudoterapia con sanguijuelas vivas ni compuestos aislados de sanguijuela.
Citación
Chinese herbal medicine for aspirin resistance: a systematic review of randomized controlled trials
Liu AJ et al. · Evidence-based complementary and alternative medicine : eCAM, 2014
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Añadido a la biblioteca ASH: May 27, 2026 · Última actualización del sitio: 18 de junio de 2026