Flap infection associated with medicinal leeches in reconstructive surgery: two new drug-resistant organisms
Bibbo C, Fritsche T, Stemper M, Hall M (2013) · Journal of Reconstructive Microsurgery · n=2
Perfil del estudio
- Diseño
- two-case report with management protocol review (Marshfield Clinic, Wisconsin)
- Tamaño de la muestra (n)
- 2
- Intervención
- Standard leech therapy in reconstructive surgery patients with subsequent identification of two new multidrug-resistant organisms causing flap infection
- Comparador
- Standard Aeromonas hydrophila-targeted prophylactic regimens (proven inadequate for these strains)
- Punto final primario
- Identification of novel resistant organisms and clinical management protocol
- Resultado primario
- Two new multidrug-resistant organisms identified from medicinal leech therapy resulting in flap infection; suspected leech-borne infection evaluation and management protocol presented
- Duración del seguimiento
- Postoperative infection course
- PMID
- 23599212
Hallazgos clave
- Two new multidrug-resistant organisms identified
- Beyond traditional Aeromonas hydrophila coverage
- Comorbidities: arthropathy, obesity (morbid)
- Management protocol for suspected leech-borne resistant infections
- Supports antibiogram-guided empiric therapy
Limitaciones
- Only 2 cases - cannot characterize population resistance
- Single institution experience
- Specific organisms not detailed in abstract
- Underlying comorbidities may select for resistant flora
- Cannot recommend universal protocol changes
Implicaciones clínicas
Bibbo 2013 documents two novel multidrug-resistant organisms from medicinal leech therapy and provides clinical management protocol. For US clinicians under K040187, the case report highlights the need for individualized microbiologic evaluation in suspected leech-borne infections, particularly in patients with significant comorbidities (obesity, joint disease).
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