Titration of Bivalirudin Infusion in the Pediatric Cardiac Catheterization Laboratory: A Case Report
Case report published in A&A Pract (2019)
Abstract
Bivalirudin is a direct thrombin inhibitor that is used as a procedural anticoagulant during percutaneous coronary interventions and cardiac surgery for patients with heparin-resistant thrombosis or heparin-induced thrombocytopenia. There is a robust literature describing its safety and efficacy in adults; however, its use in the pediatric population is relatively rare, with dosing extrapolated from adult data. In this case report, we describe a 4-year-old with complex congenital heart disease and history of heparin-induced thrombocytopenia who required bivalirudin dose uptitration during cardiac catheterization.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Summary
Case report of 4-year-old with complex congenital heart disease and HIT requiring bivalirudin uptitration during cardiac catheterization with successful procedural completion.
Why This Matters for Hirudotherapy
This case report describes a 4-year-old patient with complex congenital heart disease and a history of heparin-induced thrombocytopenia who required bivalirudin dose uptitration during cardiac catheterization. The abstract notes the paucity of pediatric literature and that dosing is largely extrapolated from adult data. The abstract describes bivalirudin as a direct thrombin inhibitor but does not mention hirudin, leeches, or any leech-derived compound, so no defensible hirudotherapy link exists. This is a single case report involving one patient, does not involve leeches or hirudotherapy, and provides no generalizable dosing conclusions.
Citation
Titration of Bivalirudin Infusion in the Pediatric Cardiac Catheterization Laboratory: A Case Report.
Streiff A et al. · A&A practice, 2019
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