American Society of Hirudotherapy

Use of the medicinal leech in the treatment of ear diseases

Research article published in ORL; journal for oto-rhino-laryngology and its related specialties (1992)

Last Updated: March 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Salivary PharmacologyGenomics & ProteomicsSeleznev K et al. · ORL; journal for oto-rhino-laryngology and its related specialties, 1992

Abstract

Medicinal leeches (Hirudo medicinalis) and the native secretion of their salivary glands diluted with saline (5 times) were successfully used for the treatment of some ear diseases: tinnitus caused by inner-ear affections, acute external otitis and chronic otitis media. The effect of diluted leech saliva injected into the region of the mastoid process by microelectrophoresis was 25-30% lower than that of the medicinal leeches.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article
Indexed MeSH termsAcute DiseaseAnimalsChronic DiseaseEar CanalHearing Loss, ConductiveHearing Loss, SensorineuralHumansLeechesOtitis ExternaOtitis MediaSalivaTinnitus

Summary

Medicinal leeches (Hirudo medicinalis) and the native secretion of their salivary glands diluted with saline (5 times) were successfully used for the treatment of some ear diseases: tinnitus caused by inner-ear affections, acute external otitis and chronic otitis media.

Why This Matters for Hirudotherapy

Advances understanding of leech salivary bioactive compounds and their therapeutic potential.

Citation

Use of the medicinal leech in the treatment of ear diseases.

Seleznev K et al. · ORL; journal for oto-rhino-laryngology and its related specialties, 1992

Added to ASH library: March 18, 2026 · Site last updated: March 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.

Use of the medicinal leech in the treatment of ear diseases | ASH