American Society of Hirudotherapy

The use of medicinal leeches in microsurgery

Research article published in Blood coagulation & fibrinolysis (1991)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Narrative reviewDrug DevelopmentValauri FA et al. · Blood coagulation & fibrinolysis, 1991

Abstract

Medicinal leeches have been used to treat a variety of ailments for thousands of years. During the past decade the leech has become valuable for salvaging surgically uncorrectable venous insufficiency which is occasionally encountered after microsurgical free flap and replantation procedures. Leech anatomy and physiology are reviewed. Indications and the technique for application of medicinal leeches is discussed, as well as potential complications of leeching.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeHistorical ArticleJournal ArticleReview
Indexed MeSH termsAmputation, TraumaticAnimalsBloodlettingEarFinger InjuriesHistory, 18th CenturyHistory, 19th CenturyHistory, 20th CenturyHistory, AncientHumansLeechesMicrosurgery

Summary

The use of medicinal leeches in microsurgery.

Why This Matters for Hirudotherapy

This historical review discussed the use of medicinal leeches over thousands of years for a variety of ailments and their contemporary role in microsurgery. The abstract notes that over the past decade, leeches have become valuable for salvaging surgically uncorrectable venous insufficiency encountered after microsurgical free flap and replantation procedures. The review covers leech anatomy and physiology, indications and technique for application, and potential complications of leeching. This article is directly relevant to the American Society of Hirudotherapy as it outlines clinical indications and practical methodology for therapeutic leeching in reconstructive surgery, providing a foundational overview for medical professionals.

Citation

The use of medicinal leeches in microsurgery

Valauri FA et al. · Blood coagulation & fibrinolysis, 1991

Added to ASH library: May 27, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.