American Society of Hirudotherapy

Medical leech therapy in Ayurveda and biomedicine - A review

Review article published in Journal of Ayurveda and integrative medicine (2020)

Last Updated: November 1, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Narrative reviewClinical LiteratureGenomics & ProteomicsSafety & Infection ControlSingh S, Rajoria K · Journal of Ayurveda and integrative medicine, 2020

Abstract

Medicinal leech therapy or Hirudino therapy have roots back in ancient civilization. It was a prevalent form of therapy in various ailments. The novel Ayurveda text Sushruta Samhita devoted a complete chapter on hirudino therapy. In the early 20th century this therapy had a major setback due to origin and evolution of antibiotics. There was a discontinuity in the flow of knowledge about this therapy. Then, resumed and revived after few recent decades, due to its contribution in reconstructive surgeries. During this period, the research work on various aspects have been conducted. The present paper summarizes the various aspects of medicinal leech therapy both from Ayurveda text and the present knowledge and to enable the fraternity to use the both source for benefits of humankind.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal ArticleReview

Summary

This review traces medicinal leech therapy from ancient practice through the Sushruta Samhita and its twentieth-century decline after antibiotics, to revival in reconstructive surgery, summarizing Ayurvedic and biomedical knowledge of the therapy.

Why This Matters for Hirudotherapy

This review summarizes medicinal leech therapy (hirudinotherapy) from both classical Ayurveda—particularly the Sushruta Samhita, which devotes a dedicated chapter to the practice—and modern biomedical perspectives, tracing its historical use, decline with the rise of antibiotics, and contemporary revival in reconstructive surgery. The review attempts to bridge traditional Ayurvedic knowledge with current biomedical understanding to encourage integrated use for patient benefit. However, as a review, it presents no new primary data, clinical outcomes, or mechanistic analyses of leech salivary components. The abstract does not indicate a systematic methodology or critical appraisal of sources, and its contribution is primarily historical and conceptual rather than providing quantitative evidence on efficacy or the molecular basis of leech therapy.

Citation

Reference (Vancouver style)

Singh SK, Rajoria K. Medical leech therapy in Ayurveda and biomedicine - A review. J Ayurveda Integr Med. 2020;11(4):554-564. doi:10.1016/j.jaim.2018.09.003. PMID: 30709686

Bibliographic details (authors, volume, pages, DOI) are taken from the PubMed record.

Added to ASH library: March 18, 2026 · Site last updated: November 1, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.