A clinical trial for evaluation of leech application in the management of Vicarcikā (Eczema)
Research article published in Ancient science of life (2014)
Abstract
BACKGROUND: Skin diseases are among the most common health problems worldwide and are associated with a considerable burden. Eczema is such a skin ailment which cause psychological, social and financial burden on the patient and their families. Management of eczema with antibiotics, antihistamines, steroids etc., are available but even after their use relapses, recurrences and other complications are very common. AIM: The aim of this study was to assess the efficacy of leech application in the management of vicarcikā (Eczema) with standard clinical parameters viz. Eczema Area and Severity Index (EASI) score, SCORing of Atopic Dermatitis (SCORAD) Index and Dermatology Life Quality Index (DLQI). MATERIALS AND METHODS: An open labeled clinical trial study without control group was conducted with 27 patients having the classical symptoms of vicarcikā (Eczema), selected as per the inclusion and exclusion criteria from outpatient department and inpatient department sections of Shalya Department, S.V. Ayurvedic Hospital, Tirupati. Minimum four sittings of leech application were carried out with 7 days interval. Pre- and post-treatment evaluation of the patient was done with Eczema Area and Severity Index (EASI) score, SCORing of Atopic Dermatitis (SCORAD) Index and Dermatology Life Quality Index (DLQI). STATISTICAL ANALYSIS: Analysis of the data was done with Student's paired t-test. RESULTS: The total EASI score showed considerable reduction up to 54.45% (P < 0.01) and the SCORAD Index significantly reduced by 55% (P < 0.01). The life quality of the patient calculated by DLQI improved significantly by 62.36% (P < 0.01). CONCLUSION: Leech application gives significant relief for the symptoms of eczema. The life quality of the patient also improved significantly after leech therapy. No adverse reactions were reported during the entire course of study.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Summary
In an open-label trial, 27 patients with vicarcikā (eczema) received at least four leech applications; EASI scores fell up to 54.45%, SCORAD by 55% and quality-of-life (DLQI) improved 62.36%, all P < 0.01, with no adverse reactions.
Why This Matters for Hirudotherapy
This study examined the efficacy of leech application in managing vicarcikā (eczema) using standardized clinical measures — the Eczema Area and Severity Index (EASI), SCORing of Atopic Dermatitis (SCORAD) Index, and Dermatology Life Quality Index (DLQI) — in 27 patients who received a minimum of four leech application sessions at seven-day intervals. It is directly relevant to hirudotherapy, as it reports prospective clinical outcome data indicating statistically significant reductions in eczema severity (EASI ~54%, SCORAD ~55%) and improved quality of life (DLQI ~62%) with no adverse reactions observed during the study. However, as the abstract explicitly states this was an open-label trial without a control group, observed improvements cannot be confidently attributed to leech therapy alone over natural disease fluctuation or placebo effects; the modest sample and single-arm design warrant confirmation through controlled comparative studies before broader clinical conclusions can be drawn.
Citation
Reference (Vancouver style)
Shankar KM, Rao SD, Umar SN, Gopalakrishnaiah V. A clinical trial for evaluation of leech application in the management of Vicarcikā (Eczema). Anc Sci Life. 2014;33(4):236-241. doi:10.4103/0257-7941.147432. PMID: 25593404
Bibliographic details (authors, volume, pages, DOI) are taken from the PubMed record.
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