American Society of Hirudotherapy

Leech Application-related Upper Gastrointestinal Bleeding: A Case Report

Case report published in Bulletin of emergency and trauma (2023)

Last Updated: November 1, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Case reportSafety & Infection ControlDolek U et al. · Bulletin of emergency and trauma, 2023

Abstract

Leech therapy (Hirudotherapy) is a method used in the treatment of many diseases since ancient times. Although many complications have been reported following the use of this method, no systemic life-threatening bleeding has yet been described. A-43-year-old male patient was diagnosed with upper gastrointestinal bleeding following leech application that he had received for infertility one week earlier. The complications of hirudotherapy typically spontaneously improve due to the local effects of this treatment. The most frequently reported complications are local infections, and less commonly allergies and prolonged local bleeding can occur. However, in this case report, we describe a life-threatening upper gastrointestinal bleeding as a new complication. Gastrointestinal bleeding appearing a week after leech therapy does not necessarily mean that leeches caused gastrointestinal bleeding in this case. Nevertheless, considering the development time of gastrointestinal bleeding, it can be deduced that it was possibly due to hirudotherapy. Patients should be informed about alarming symptoms that can indicate complications following leech application.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeCase ReportsJournal Article

Summary

A 43-year-old man developed life-threatening upper gastrointestinal bleeding one week after leech application for infertility; the authors caution that although causality is uncertain given the timing, it may be a hirudotherapy complication, and patients should be warned about alarming symptoms.

Why This Matters for Hirudotherapy

This case report describes a 43-year-old male who developed upper gastrointestinal bleeding one week after receiving leech therapy for infertility, which the authors propose as a newly recognized, potentially life-threatening complication of hirudotherapy. The report documents a serious adverse event temporally associated with leech application and underscores the importance of informing patients about alarming symptoms that may arise after treatment. However, as a single case report, it cannot establish causation, and the authors themselves note that the bleeding does not necessarily mean leeches were responsible.

Citation

Reference (Vancouver style)

Dolek UC, Ozdemir S, Babayeva K, Gol M. Leech Application-related Upper Gastrointestinal Bleeding: A Case Report. Bull Emerg Trauma. 2023;11(1):47-50. doi:10.30476/BEAT.2023.97246.1403. PMID: 36818053

Bibliographic details (authors, volume, pages, DOI) are taken from the PubMed record.

Added to ASH library: March 18, 2026 · Site last updated: November 1, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.