American Society of Hirudotherapy

Leech Me Alone! Atraumatic Hemarthrosis after Hirudotherapy

Case report published in Cureus (2020)

Last Updated: November 1, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Case reportClinical LiteratureSafety & Infection ControlCurcio J, Lloyd C · Cureus, 2020

Abstract

A 58-year-old male presented to the emergency department with a chief complaint of knee pain and swelling after performing hirudotherapy (leech therapy) approximately one week prior. Knee arthrocentesis demonstrated significant hemarthrosis. Hirudotherapy is being used for a broad array of reasons including treatment of osteoarthritis, to plastic and reconstructive surgery. Case reports and journal articles often discuss cutaneous reactions, bleeding, and infection as common adverse events. Intra-articular bleeding is not commonly mentioned. With hirudotherapy being utilized more as alternative therapy for osteoarthritis and joint pain, physicians should be aware of hemarthrosis as a possible adverse reaction.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeCase ReportsJournal Article

Summary

A 58-year-old man developed knee pain and swelling roughly one week after leech therapy, and arthrocentesis showed significant hemarthrosis; the authors warn that intra-articular bleeding, though rarely mentioned, is a possible adverse reaction to hirudotherapy.

Why This Matters for Hirudotherapy

This case report describes a 58-year-old male who presented with knee pain and swelling approximately one week after performing hirudotherapy, with arthrocentesis revealing significant hemarthrosis. The observation is directly relevant to the clinical practice of hirudotherapy—particularly its use as an alternative therapy for osteoarthritis—by identifying intra-articular bleeding as a potential adverse reaction. While existing literature often focuses on cutaneous reactions, localized bleeding, and infection, this case highlights the need for physicians to recognize deeper joint bleeding as a possible complication. However, because this is a single case report, it cannot establish the true incidence or prevalence of hemarthrosis following leech applications, nor does it provide mechanistic insights into how the leech salivary secretome might induce this specific complication.

Citation

Reference (Vancouver style)

Curcio J, Lloyd CM. Leech Me Alone! Atraumatic Hemarthrosis after Hirudotherapy. Cureus. 2020;12(2):e6915. doi:10.7759/cureus.6915. PMID: 32190470

Bibliographic details (authors, volume, pages, DOI) are taken from the PubMed record.

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This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.