American Society of Hirudotherapy

Kounis syndrome due to hirudotherapy (leech therapy) in emergency department; a case report

Case report published in Turkish journal of emergency medicine (2018)

Last Updated: March 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Safety & Infection ControlClinical TrialsÇakmak T et al. · Turkish journal of emergency medicine, 2018

Abstract

Kounis Syndrome is the development of acute coronary syndrome (ACS) because of allergic reactions; allergens, such as foods, insect venom, iodine contrast agent or drugs can cause this syndrome. Hirudotherapy (leech therapy) is increasingly used as a useful therapeutic option in a variety of medical and surgical procedures, and potential complications related to this therapy include Aeromonas species infections, bleeding, anemia and allergic reactions. Here, we present a patient diagnosed as Type 1 Kounis Syndrome after using hirudotherapy for her knee aches. 41-year-old woman admitted to emergency department with sudden onset of face edema, shortness of breath and chest pain complaints and diagnosed as an allergic reaction and anaphylaxis due to leech therapy. Kounis Syndrome should be considered in acute coronary syndrome patients who were admitted to emergency department with anaphylaxis clinic.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeCase ReportsJournal Article

Summary

Kounis Syndrome is the development of acute coronary syndrome (ACS) because of allergic reactions; allergens, such as foods, insect venom, iodine contrast agent or drugs can cause this syndrome.

Why This Matters for Hirudotherapy

Informs safety protocols and infection prevention strategies for clinical leech therapy.

Citation

Kounis syndrome due to hirudotherapy (leech therapy) in emergency department; a case report.

Çakmak T et al. · Turkish journal of emergency medicine, 2018

Added to ASH library: March 18, 2026 · Site last updated: March 18, 2026

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Kounis syndrome due to hirudotherapy (leech therapy) in emergency department; a case report | ASH