American Society of Hirudotherapy

Closed Genome Sequence of Aeromonas veronii Strain Hm21, an Isolate from the Medicinal Leech Hirudo verbana

Research article published in Microbiology resource announcements (2020)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Research reportSafety & Infection ControlClinical TrialsGraf J et al. · Microbiology resource announcements, 2020

Abstract

Aeromonas veronii strain Hm21 was isolated from the medicinal leech Hirudo verbana and is used for genetic studies. We present here the 4.71-Mbp genome with a 56-kb plasmid and identify the mutations present in strains commonly used for genetic engineering.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article

Summary

strain Hm21 was isolated from the medicinal leechand is used for genetic studies.

Why This Matters for Hirudotherapy

This genome announcement reports a closed 4.71-Mbp genome (plus a 56-kb plasmid) for Aeromonas veronii strain Hm21, isolated from the medicinal leech Hirudo verbana and used for genetic studies, and identifies mutations in strains commonly used for genetic engineering. This is directly relevant to hirudotherapy safety: Aeromonas is the well-known gut symbiont of medicinal leeches and the principal source of post-leech-therapy wound infections, so a high-quality reference genome supports understanding and surveillance of this clinically important organism. The caveat is that this is a brief genomic resource announcement, not a clinical or infection-outcome study; it provides a sequencing tool and identifies engineering-strain mutations but reports no patient data, infection rates, or treatment implications.

Citation

Closed Genome Sequence of Aeromonas veronii Strain Hm21, an Isolate from the Medicinal Leech Hirudo verbana

Graf J et al. · Microbiology resource announcements, 2020

Added to ASH library: May 27, 2026 · Site last updated: June 18, 2026

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