American Society of Hirudotherapy

Use of heparin cream for venous congestion in the extended reverse metacarpal artery flap

Case report published in Arch Plast Surg (2022)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Research reportClinical TrialsTatar et al. · Archives of plastic surgery, 2022

Abstract

Finger dorsum defects are a challenging situation. Many reconstruction methods are used in these defects. Extended reverse dorsal metacarpal artery (RDMA) flap is used in dorsal finger reconstruction. Venous congestion in this flap is most important cause of flap failure. In this case, we presented a case in which we used heparin cream due to development of venous congestion in our patient who underwent an extended RDMA flap. A 24-year-old female patient presented to the emergency department with a defect of dorsal of left-hand fourth finger. Defect was covered with an extended RDMA flap. On postoperative first day, venous congestion was observed, and heparin cream was applied three times a day on flap. The signs of venous congestion were regressed. Tissue healed as a result of superficial epidermolysis and skin grafting. No functional limitation was observed in sixth-month postoperative control. Venous congestion is the most important cause of flap failure of extended RDMA flaps. Generally, subcutaneous heparin administration and leech therapy are used. In our case, heparin was applied as a cream instead of subcutaneously, and flap healing was observed as a result of superficial epidermolysis. Heparin cream application can also be used as a treatment option in flaps with venous congestion.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article

Summary

Extended reverse metacarpal artery flap venous congestion managed with heparin cream as alternative to leech therapy.

Why This Matters for Hirudotherapy

This case report describes a 24-year-old female who developed venous congestion in an extended reverse dorsal metacarpal artery (RDMA) flap used to cover a dorsal finger defect; topical heparin cream applied three times daily led to regression of congestion, with healing via superficial epidermolysis and skin grafting. The abstract explicitly notes that subcutaneous heparin and leech therapy are generally used for venous congestion in such flaps, making the article tangentially relevant to ASH by acknowledging leech therapy as a standard treatment modality for flap venous congestion. However, the study itself concerns an alternative (heparin cream) to leech therapy rather than evaluating leeching directly, and reports only a single case with no comparative or controlled data.

Citation

Use of heparin cream for venous congestion in the extended reverse metacarpal artery flap.

Tatar et al. · Archives of plastic surgery, 2022

Added to ASH library: May 27, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.