American Society of Hirudotherapy

Salvage of pedicled anterolateral thigh flap for closure of a massive full-thickness abdominal wall defect using modified Perez protocol for chemical leeching - a case report

Case report published in J Surg Case Rep (2026)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Case reportClinical TrialsSafety & Infection ControlBabalola OF et al. · Journal of surgical case reports, 2026

Abstract

The aim of this case report is to spotlight the effectiveness of the Perez protocol for chemical leeching in rescuing a large pedicled anterolateral thigh fasciocutaneous flap endangered by diffuse venous congestion. A review of the case file, clinical photographs, radiological, and histopathological studies of the patient was conducted. Venous congestion was detected on the 2nd postoperative day in a 51-year-old woman who had pedicled anterolateral thigh flap coverage of a massive post-tumour resection full-thickness abdominal wall defect. The Perez protocol was initiated immediately and continued for 14 days. A slight modification of the dosage was necessitated by the volume of flap tissue involved. Partial salvage of the flap was achieved by the 14th postoperative day with no visceral exposure. The residual granulation on the flap was resurfaced with a meshed split-thickness skin graft. We affirmed the reliability of Perez's protocol as a reliable guide for managing flap venous congestion.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeCase ReportsJournal Article

Summary

Case of a 51-year-old woman whose pedicled anterolateral thigh flap covering a massive abdominal wall defect developed diffuse venous congestion on postoperative day 2; chemical leeching via the modified Perez protocol over 14 days achieved partial flap salvage.

Why This Matters for Hirudotherapy

Documents a non-biological (chemical leeching) alternative when live leeches are unavailable — relevant context for ASH product positioning.

Citation

Salvage of pedicled anterolateral thigh flap for closure of a massive full-thickness abdominal wall defect using modified Perez protocol for chemical leeching - a case report.

Babalola OF et al. · Journal of surgical case reports, 2026

Added to ASH library: May 27, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.