American Society of Hirudotherapy

VoronaGasyCodes: A Public Database of Mitochondrial Barcodes for Malagasy Birds

Research article published in Mol Ecol Resour (2025)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Preclinical (animal)Clinical TrialsReddy S et al. · Mol Ecol Resour, 2025

Abstract

Molecular tools are increasingly being used to survey the presence of biodiversity and their interactions within ecosystems. Indirect methods, like environmental DNA (eDNA) and invertebrate-derived DNA (iDNA), are dependent on sequence databases with accurate and sufficient taxonomic representation. These methods are increasingly being used in regions and habitats where direct detection or observations can be difficult for a variety of reasons. Madagascar is a biodiversity hotspot with a high proportion of endemic species, many of which are threatened or endangered. Here we describe a new resource, VoronaGasyCodes, a curated database of newly published genetic sequences from Malagasy birds. Our database is currently populated with six mitochondrial genes or DNA barcodes for 142 species including 70% of the birds endemic to the island and will be periodically updated as new data become available. We demonstrate the utility of our database with an iDNA study of leech blood meals where we successfully identified 77% of the hosts to species. These types of resources for characterising biodiversity are critical for insights into species distribution, discovery of new taxa, novel ecological connections and advancing conservation and restoration measures.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article
Indexed MeSH termsAnimalsMadagascarBirdsDNA Barcoding, TaxonomicDNA, MitochondrialBiodiversityDatabases, Genetic

Summary

Molecular tools are increasingly being used to survey the presence of biodiversity and their interactions within ecosystems.

Why This Matters for Hirudotherapy

This article describes the creation of VoronaGasyCodes, a curated public database of mitochondrial DNA barcodes for Malagasy birds, intended to advance biodiversity and conservation research. To demonstrate the database's utility, the authors successfully used it to identify host species from leech blood meals via invertebrate-derived DNA (iDNA). While this study highlights the use of leeches as ecological sampling tools for wildlife monitoring, it has no relevance to hirudotherapy or leech-based therapeutics. The research relies on leeches merely as a means of data collection for avian biodiversity and offers no insights into the leech secretome or clinical applications.

Citation

VoronaGasyCodes: A Public Database of Mitochondrial Barcodes for Malagasy Birds.

Reddy S et al. · Mol Ecol Resour, 2025

Added to ASH library: May 27, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.