Stroke After Transcatheter Aortic Valve Replacement: Incidence, Definitions, Etiologies and Management Options
Review published in Journal of cardiothoracic and vascular anesthesia (2017)
Abstract
Neurologic complications after transcatheter aortic valve replacement are devastating. The etiologies of stroke in this setting are best addressed in an integrated fashion during each phase of the perioperative pathway. The conduct of this triphasic approach will continue to be refined to reduce the stroke risks even further, given the major focus on aspects such as embolic protection devices and valve thrombosis. This neurologic focus in transcatheter aortic valve replacement has transformed the investigational approach to neurologic events in cardiovascular clinical trials, resulting in novel guidelines for the diagnosis and assessment of neurologic injury after cardiovascular interventions.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Summary
Neurologic complications after transcatheter aortic valve replacement are devastating.
Why This Matters for Hirudotherapy
This article addresses neurologic complications after transcatheter aortic valve replacement, emphasizing a triphasic perioperative approach to addressing stroke etiologies and noting the roles of embolic protection devices and valve thrombosis. It also discusses novel guidelines for the diagnosis and assessment of neurologic injury after cardiovascular interventions. There is no mention of leeches, hirudotherapy, hirudin, or leech-derived agents anywhere in the abstract. Consequently, this article has no defensible relevance to ASH's domain of hirudotherapy or the leech secretome, and is included only for completeness.
Citation
Stroke After Transcatheter Aortic Valve Replacement: Incidence, Definitions, Etiologies and Management Options
Patel PA et al. · Journal of cardiothoracic and vascular anesthesia, 2017
Added to ASH library: May 27, 2026 · Site last updated: June 18, 2026