American Society of Hirudotherapy

Stroke After Transcatheter Aortic Valve Replacement: Incidence, Definitions, Etiologies and Management Options

Review published in Journal of cardiothoracic and vascular anesthesia (2017)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Narrative reviewClinical LiteraturePatel PA et al. · Journal of cardiothoracic and vascular anesthesia, 2018

Abstract

Neurologic complications after transcatheter aortic valve replacement are devastating. The etiologies of stroke in this setting are best addressed in an integrated fashion during each phase of the perioperative pathway. The conduct of this triphasic approach will continue to be refined to reduce the stroke risks even further, given the major focus on aspects such as embolic protection devices and valve thrombosis. This neurologic focus in transcatheter aortic valve replacement has transformed the investigational approach to neurologic events in cardiovascular clinical trials, resulting in novel guidelines for the diagnosis and assessment of neurologic injury after cardiovascular interventions.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal ArticleReview
Indexed MeSH termsCognitionHumansIncidenceStrokeTranscatheter Aortic Valve Replacement

Summary

This review outlines the incidence, definitions, causes and management of stroke after transcatheter aortic valve replacement, arguing for an integrated perioperative approach covering each phase and shaped by embolic protection devices and valve thrombosis.

Context

This article addresses neurologic complications after transcatheter aortic valve replacement, emphasizing a triphasic perioperative approach to addressing stroke etiologies and noting the roles of embolic protection devices and valve thrombosis. It also discusses novel guidelines for the diagnosis and assessment of neurologic injury after cardiovascular interventions. There is no mention of leeches, hirudotherapy, hirudin, or leech-derived agents anywhere in the abstract.

Citation

Reference (Vancouver style)

Patel PA, Patel S, Feinman JW, Gutsche JT, Vallabhajosyula P, Shah R, et al. Stroke After Transcatheter Aortic Valve Replacement: Incidence, Definitions, Etiologies and Management Options. J Cardiothorac Vasc Anesth. 2018;32(2):968-981. doi:10.1053/j.jvca.2017.08.034. PMID: 29174745

Bibliographic details (authors, volume, pages, DOI) are taken from the PubMed record.

DOIPubMed

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