American Society of Hirudotherapy

Learning microvascular anastomosis: Analysis of practice patterns.

Research article published in Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia (2021)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Randomized controlled trialClinical TrialsMokhtari et al. · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021

Abstract

Performing a successful microsurgical vascular anastomosis (MVA) is challenging and requires lots of practice. However, the most efficient practice protocol is yet to be found. We aimed to compare and analyze two major practice patterns for fine motor tasks as applied to learning MVA: distributed and mass practice protocols. Ten neurosurgeons with comparable experience in microsurgery (but no experience in vascular anastomosis) were randomized to practice MVA either using a distributed (1 session/day) or a mass practice (6 sessions/day) protocol. A total of 24 sessions of practice and 2 recall test sessions were given. Anastomosis score, time to complete a single stitch and the total time to complete an anastomosis were recorded. Mass practice protocol caused a clear fatigue effect observed toward the end of each mass practice trial block. Statistical comparison using one-way analysis of variance showed significantly higher anastomosis scores and shorter times to place a single stitch as well as to complete the anastomosis in distributed practice group for the last 3 acquisition practice trials, and the 2 recall tests (p < 0.05). The relative advantage of the distributed practice protocol could be attributed to forgetting/spacing effect. Although mass practice protocol resulted in worse performance, it still showed a gradual improvement trend in performance from beginning to the end. Therefore, certain adjustments to a mass practice protocol (such as increasing the number of practice blocks) could potentially lead to an eventual performance level comparable to a distributed protocol. This point is a subject of further investigation.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal ArticleRandomized Controlled Trial
Indexed MeSH termsAnastomosis, SurgicalClinical CompetenceHumansLearningMicrosurgeryNeurosurgeonsSimulation Training

Summary

Learning microvascular anastomosis: Analysis of practice patterns.

Why This Matters for Hirudotherapy

This small randomized study compared distributed (1 session/day) versus mass (6 sessions/day) practice protocols for learning microsurgical vascular anastomosis in ten neurosurgeons, finding that the distributed-practice group achieved significantly higher anastomosis scores and faster stitch and completion times on the final acquisition trials and both recall tests (p<0.05). It is relevant to hirudotherapy because microvascular/reconstructive surgery is the principal modern clinical setting for medicinal leeching: leeches are applied to relieve venous congestion in flaps, replants, and free-tissue transfers whose survival depends on the quality of exactly these anastomoses. Better surgical training therefore sits upstream of the salvage scenarios where hirudotherapy is deployed. Honest caveat: this is a preliminary skills-acquisition trial with only ten participants and no patient outcomes, and it does not study leeches or hirudotherapy at all, only the training of the surgery they support.

Citation

Learning microvascular anastomosis: Analysis of practice patterns.

Mokhtari et al. · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021

Added to ASH library: May 28, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.