American Society of Hirudotherapy

The Use of Medicinal Leeches for the Treatment of Venous Congestion in Replanted or Revascularized Digits

Retrospective case series published in J Hand Surg Am (2018)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Research reportClinical LiteratureArami A et al. · The Journal of hand surgery, 2018

Abstract

PURPOSE: A noteworthy cause of failure in digital replantation is venous insufficiency. External bloodletting with medicinal leeches is a common treatment for venous insufficiency after distal digital replantations. The objective of this study was to evaluate the salvage rate of digits replanted proximal to the distal interphalangeal (DIP) joint that were treated with medicinal leeches for venous congestion. METHODS: We retrospectively reviewed the charts of patients with complete or incomplete digit amputation admitted between January, 2008 and April, 2014. We included all patients with venous congestion in one or more digits replanted or revascularized at the middle or proximal phalangeal level, who were treated with medicinal leeches. Treatment initiation and duration were based on clinical judgment. Demographic, therapy, and surgical data were collected. RESULTS: Of 145 patients with 205 digits that were replanted or revascularized, 25 digits were treated with medicinal leeches for venous congestion. Venous congestion was diagnosed later than 48 hours after operation in 24 of the 25 digits. Of the 25 digits, 11 survived (44.4%) (8 of 22 replanted digits and all 3 revascularized digits). No complications were recorded except for substantial blood loss requiring transfusion in one patient. CONCLUSIONS: External bloodletting with medical leeches might be less effective with late treatment or with a higher volume of congested tissue, as is characteristic of proximal finger replantation. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article
Indexed MeSH termsAdolescentAdultAmputation, TraumaticAnimalsChildChild, PreschoolFemaleFinger InjuriesFingersGraft SurvivalHumansLeechingMaleMiddle AgedReplantationRetrospective StudiesVenous InsufficiencyYoung Adult

Summary

Of 25 digits with venous congestion after replantation or revascularization at middle or proximal phalangeal level, medicinal leech treatment salvaged 11 (44.4%); the authors suggest it may be less effective when treatment is late or tissue volume is high.

Why This Matters for Hirudotherapy

This study retrospectively reviewed 25 digits replanted or revascularized proximal to the DIP joint that were treated with medicinal leeches for venous congestion, drawn from 145 patients with 205 digits over a six-year period. The overall survival rate was 44.4% (8 of 22 replanted digits and all 3 revascularized digits), with venous congestion diagnosed later than 48 hours postoperatively in 24 of 25 digits; one patient required transfusion for substantial blood loss. The study provides clinical outcome data for hirudotherapy in a specific surgical application. Caveats: the study is retrospective (explicitly stated) with therapeutic level IV evidence and no concurrent control group, and the authors themselves suggest leech therapy may be less effective with late treatment initiation or larger volumes of congested tissue.

Citation

Reference (Vancouver style)

Arami A, Gurevitz S, Palti R, Menachem S, Berelowitz M, Yaffe B. The Use of Medicinal Leeches for the Treatment of Venous Congestion in Replanted or Revascularized Digits. J Hand Surg Am. 2018;43(10):949.e1-949.e5. doi:10.1016/j.jhsa.2018.02.018. PMID: 29602653

Bibliographic details (authors, volume, pages, DOI) are taken from the PubMed record.

Added to ASH library: May 26, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.