American Society of Hirudotherapy

Medicinal Leech Therapy in Veterinary Medicine: A Retrospective Study

Research article published in Journal of the American Animal Hospital Association (2022)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Preclinical (animal)Clinical TrialsKermanian C, Buote N, Bergman P · Journal of the American Animal Hospital Association, 2022

Abstract

The objective of this study was to report the clinical indications, outcomes, and complications associated with medicinal leech therapy (MLT) in dogs and cats. Medical records (2012-2016) of client-owned dogs (n = 9) and cats (n = 3) treated with MLT at one institution were retrospectively reviewed. Retrieved data included the signalment, indications, physical examination findings, laboratory results, methods of leeching, outcomes, and complications associated with MLT. Following MLT sessions, nine patients (75%) visibly showed clear improvement of the affected tissue. One patient (8%) was euthanized before complete healing owing to pulmonary parenchymal disease. Improvement or appearance of tissue following MLT was not recorded in two patients (17%). Results suggest that MLT may be a safe and effective treatment modality for venous congestion and necrosis in compromised skin flaps and wounds with success in resolving 75% of the lesions in this study. This study is suggestive of the value of MLT when more conventional treatment methods fail in dogs and cats. A data collection form was created for veterinarians to use with the goal of obtaining standardized, objective MLT data for future studies.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article
Indexed MeSH termsCatsDogsAnimalsLeechingRetrospective StudiesCat DiseasesDog DiseasesSurgical Flaps

Summary

The objective of this study was to report the clinical indications, outcomes, and complications associated with medicinal leech therapy (MLT) in dogs and cats.

Why This Matters for Hirudotherapy

This retrospective study examined clinical indications, outcomes, and complications of medicinal leech therapy (MLT) in 12 client-owned dogs and cats (2012–2016) at a single veterinary institution, reporting visible tissue improvement in 75% of patients treated for venous congestion and necrosis in compromised skin flaps and wounds. The study is directly relevant to hirudotherapy, providing clinical outcome data on leech use in a veterinary setting and proposing a standardized data collection form to encourage prospective, objective MLT data gathering in future veterinary practice. For ASH's domain, it extends the evidence base for medicinal leech applications beyond human medicine and highlights the importance of systematic documentation of leeching methods, complications, and tissue response. However, the study is limited by its small sample size (n = 12), single-institution design, and retrospective nature, which preclude definitive efficacy conclusions; the authors themselves frame results as suggestive rather than conclusive, and controlled comparative trials would be needed to validate these preliminary veterinary outcomes.

Citation

Medicinal Leech Therapy in Veterinary Medicine: A Retrospective Study.

Kermanian C, Buote N, Bergman P · Journal of the American Animal Hospital Association, 2022

Added to ASH library: March 18, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.