American Society of Hirudotherapy

Management of flaps with compromised venous outflow in head and neck microsurgical reconstruction

Narrative review published in Microsurgery (2002)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Narrative reviewClinical TrialsKubo T, Yano K, Hosokawa K · Microsurgery, 2002

Abstract

Microvascular tissue transfer has become an indispensable procedure for head and neck reconstruction. Although remarkable progress has been made technically, anastomosed vessel occlusion is still a serious complication. Even with technically skilled microsurgeons, anastomosed vessel occlusion occurs because the technique is not the sole prophylaxis against thrombosis in microsurgery. Therefore, to minimize the possibility of an unfavorable result in microsurgery, microsurgeons must be familiar with management options for a vascular compromised flap. Most investigators have agreed that venous obstruction occurs more often than arterial obstruction. Here, we reviewed the published literature on the salvage of venous compromised flaps from the viewpoints of surgical correction, including reanastomosis and catheter thrombectomy, and nonsurgical procedures, such as a medicinal leech, hyperbaric oxygen, and thrombolytic therapy.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal ArticleReview
Indexed MeSH termsAnastomosis, SurgicalHead and Neck NeoplasmsHumansMicrosurgeryPostoperative ComplicationsPlastic Surgery ProceduresSurgical FlapsVenous Insufficiency

Summary

Reviews surgical (reanastomosis, catheter thrombectomy) and nonsurgical (medicinal leech, hyperbaric oxygen, thrombolytics) options for venous-compromised flaps in head and neck reconstruction.

Why This Matters for Hirudotherapy

This review of the published literature surveys options for salvaging venous-compromised flaps in head and neck microsurgical reconstruction, noting that venous obstruction is more common than arterial and covering both surgical correction (reanastomosis, catheter thrombectomy) and nonsurgical measures, among them medicinal leeches, hyperbaric oxygen, and thrombolytic therapy. For ASH it places leech therapy within the recognized reconstructive-surgery toolkit for venous congestion, the indication for which hirudotherapy is most established in mainstream surgical practice. The caveat is that this is a narrative review summarizing others' reports rather than primary or comparative data, so it documents leeches as one accepted salvage option without quantifying their relative effectiveness.

Citation

Management of flaps with compromised venous outflow in head and neck microsurgical reconstruction.

Kubo T, Yano K, Hosokawa K · Microsurgery, 2002

Added to ASH library: May 26, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.