American Society of Hirudotherapy

Leeches and hand surgery: history, physiology, and a scoping review

Scoping review published in Hand Surg Rehabil (2026)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Narrative reviewClinical TrialsSafety & Infection ControlChabridon AI et al. · Hand surgery & rehabilitation, 2026

Abstract

INTRODUCTION: Leech therapy or hirudotherapy has been part of the medical therapies and treatment for centuries. Their use decreased in the 19th century with the launch of asepsis and the great cholera epidemic in 1832. Later on, in 1980s, they were reintroduced in the management of post-operative venous congestion. Well known for free/pedicled flaps surgery, their use in hand surgery is more inconsistent. The purpose of this study was to review history, physiology of the leeches, and their use specifically in hand surgery. MATERIALS AND METHODS: The bibliography was compiled using the PubMed and Google Scholar databases from January 2004 to September 2024 using the PRISMA method. The keywords used were: "hirudotherapy," "leech therapy," and "hand surgery." Articles in English and French were selected. Reviews of other studies and researches were excluded. RESULTS: Among 55 documents screened, thirteen articles were selected. Most studies were americans, and they dated back to 2004 with the most recent article published in 2024. These were retrospective studies with follow-up periods ranging from 2 to 15 years. Leeches were used to reduce venous congestion in revascularizations and replantations. Leech treatment duration ranged from approximately 1-7 days. Application was once a day to each two hours. The most frequent complications linked to hirudotherapy were infection and anemia which required repeated transfusions. Its effectiveness appears to be around 50%. CONCLUSION: Hirudotherapy is a complementary therapy frequently used in hand surgery as a result of its effectiveness. In fact, it should be included as an integral part of the therapeutic approach in the event of venous congestion if surgery is insufficient.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal ArticleReview

Summary

Scoping review (PRISMA, 2004-2024) of 13 selected articles on hirudotherapy in hand surgery. Documents leech use in revascularizations and replantations with treatment durations of 1-7 days, effectiveness around 50%, and frequent complications (infection, anemia requiring transfusions).

Why This Matters for Hirudotherapy

This review examines the history, physiology, and clinical use of leech therapy specifically in hand surgery, screening 55 documents and selecting 13 articles from 2004–2024, most from American centers. Leeches were used to reduce venous congestion in revascularizations and replantations, with treatment durations of approximately 1–7 days and application frequencies ranging from once daily to every two hours. The most frequent complications were infection and anemia requiring repeated transfusions, with effectiveness reported at around 50%. The review concludes that hirudotherapy should be included as an integral part of the therapeutic approach for venous congestion when surgery is insufficient. For ASH's domain, this is directly relevant as a synthesis of hirudotherapy practice in a surgical subspecialty.

Citation

Leeches and hand surgery: history, physiology, and a scoping review.

Chabridon AI et al. · Hand surgery & rehabilitation, 2026

Added to ASH library: May 27, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.