American Society of Hirudotherapy

Successful salvage of venous thrombosis of a free flap by creation of a venocutaneous fistula.

Research article published in Journal of reconstructive microsurgery (2011)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Case reportClinical TrialsJones et al. · Journal of reconstructive microsurgery, 2011

Abstract

This report describes the creation of a venocutaneous fistula to salvage a free fibular osteocutaneous flap compromised by extensive venous thrombosis. This technique has previously been described for salvage of digital replants, but this is the first report of a venocutaneous fistula being used to salvage a free flap. A 21-year-old woman underwent a 9-cm resection of the distal left tibia for an aneurysmal bone cyst. A contralateral right fibular osteocutaneous free flap was used for reconstruction. On postoperative day 2, the skin paddle showed evidence of venous congestion. Reexploration demonstrated extensive thrombosis throughout the entire venous system of the flap. The venae comitantes were transected as far back as possible and brought to the surface of the skin through two small stab wounds to allow venous egress. After a short course of heparin and dextran, the skin flap healed uneventfully and both osteosynthesis sites consolidated. A venocutaneous fistula provides a path of relatively low resistance for venous outflow, improving the arterial inflow-venous outflow balance for a short time until neovascularization and collateral venous channels develop. The venocutaneous fistula technique may be considered for salvage of free flaps compromised by extensive venous thrombosis.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeCase ReportsJournal Article
Indexed MeSH termsArteriovenous Shunt, SurgicalFemaleFollow-Up StudiesFracture Fixation, IntramedullaryFractures, ClosedFree Tissue FlapsHumansMagnetic Resonance ImagingRadiographyPlastic Surgery ProceduresRecovery of FunctionReoperation

Summary

Successful salvage of venous thrombosis of a free flap by creation of a venocutaneous fistula.

Why This Matters for Hirudotherapy

Jones et al. (2011, J. Reconstr. Microsurg.) report a single case in which a free fibular osteocutaneous flap, compromised by extensive venous thrombosis after distal-tibia reconstruction in a 21-year-old woman, was salvaged by creating a venocutaneous fistula — bringing the transected venae comitantes to the skin surface to provide low-resistance venous outflow until neovascularization developed — with the flap healing after a short course of heparin and dextran. This is directly relevant to the clinical niche where hirudotherapy is used, since medicinal leeches are an established adjunct for relieving venous congestion in failing flaps and replants; the paper describes an alternative surgical egress technique addressing the same arterial-inflow/venous-outflow imbalance that leech therapy targets, useful context for ASH's flap-salvage evidence map. Honest caveats: this is a single case report (lowest level of evidence, not generalizable), it describes a surgical fistula rather than leech therapy, and leeches are not the intervention studied here.

Citation

Successful salvage of venous thrombosis of a free flap by creation of a venocutaneous fistula.

Jones et al. · Journal of reconstructive microsurgery, 2011

Added to ASH library: May 28, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.